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Article ; Online: Bioindustrial manufacturing readiness levels (BioMRLs) as a shared framework for measuring and communicating the maturity of bioproduct manufacturing processes.

Smanski, Michael J / Aristidou, Aristos / Carruth, Ryan / Erickson, John / Gordon, Mark / Kedia, Sandeep B / Lee, Kelvin H / Prather, Darcy / Schiel, John E / Schultheisz, Heather / Treynor, Thomas P / Evans, Steven L / Friedman, Douglas C / Tomczak, Melanie

Journal of industrial microbiology & biotechnology

2022  Volume 49, Issue 5

Abstract: Readiness level (RL) frameworks such as technology readiness levels and manufacturing readiness levels describe the status of a technology/manufacturing process on its journey from initial conception to commercial deployment. More importantly, they ... ...

Abstract Readiness level (RL) frameworks such as technology readiness levels and manufacturing readiness levels describe the status of a technology/manufacturing process on its journey from initial conception to commercial deployment. More importantly, they provide a roadmap to guide technology development and scale-up from a ''totality of system'' approach. Commercialization risks associated with too narrowly focused R&D efforts are mitigated. RLs are defined abstractly so that they can apply to diverse industries and technology sectors. However, differences between technology sectors make necessary the definition of sector specific RL frameworks. Here, we describe bioindustrial manufacturing readiness levels (BioMRLs), a classification system specific to bioindustrial manufacturing. BioMRLs will give program managers, investors, scientists, and engineers a shared vocabulary for prioritizing goals and assessing risks in the development and commercialization of a bioindustrial manufacturing process.
MeSH term(s) Industry ; Technology
Language English
Publishing date 2022-09-21
Publishing country Germany
Document type Journal Article
ZDB-ID 1482484-X
ISSN 1476-5535 ; 1367-5435
ISSN (online) 1476-5535
ISSN 1367-5435
DOI 10.1093/jimb/kuac022
Database MEDical Literature Analysis and Retrieval System OnLINE

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