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  1. Conference proceedings ; Online: Morning Keynote Session; Visy's Contribution to Food Security

    Pratt, Anthony

    2015  

    Abstract: Possibly Australia’s greatest contribution to global food security is through the production and export of safe, nutritious, sustainablyproduced food, to meet the rising demand across Asia and beyond. We need to promote, protect and extend Australia’s ... ...

    Abstract Possibly Australia’s greatest contribution to global food security is through the production and export of safe, nutritious, sustainablyproduced food, to meet the rising demand across Asia and beyond. We need to promote, protect and extend Australia’s reputation as a high quality, safe food supplier. Visy supports its food industry customers to do well, which will fuel Australia’s capacity to feed 200 million people directly. We can also help feed a further 800 million with the application of our skills, R&D and business services. Supporting our food customers revitalises the food processing sector and tackles food waste by protecting food from deteriorating, which could double the effective calorie delivery from the current level of agricultural production. Reducing food waste by better packaging that extends food shelf life also adds value to our customers and hence to society. Applying business know-how, in collaborative partnership with researchers and farming practitioners, is an important key to achieving this goal.
    Keywords Agricultural and Food Policy ; Food Consumption/Nutrition/Food Safety ; Food Security and Poverty
    Language English
    Publishing country us
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Adult liver transplantation: A UK clinical guideline - part 1: pre-operation.

    Millson, Charles / Considine, Aisling / Cramp, Matthew E / Holt, Andrew / Hubscher, Stefan / Hutchinson, John / Jones, Kate / Leithead, Joanna / Masson, Steven / Menon, Krish / Mirza, Darius / Neuberger, James / Prasad, Raj / Pratt, Anthony / Prentice, Wendy / Shepherd, Liz / Simpson, Ken / Thorburn, Doug / Westbrook, Rachel /
    Tripathi, Dhiraj

    Frontline gastroenterology

    2020  Volume 11, Issue 5, Page(s) 375–384

    Abstract: Liver transplantation is a highly successful treatment for all types of liver failure, some non-liver failure indications and liver cancer. Most referrals come from secondary care. This first part of a two-part guideline outlines who to refer, and how ... ...

    Abstract Liver transplantation is a highly successful treatment for all types of liver failure, some non-liver failure indications and liver cancer. Most referrals come from secondary care. This first part of a two-part guideline outlines who to refer, and how that referral should be made, including patient details and additional issues such as those relevant to alcohol and drug misuse. The process of liver transplant assessment involves the confirmation of the diagnosis and non-reversibility, an evaluation of comorbidities and exclusion of contraindications. Finally, those making it onto the waiting list require monitoring and optimising. Underpinning this process is a need for good communication between patient, their carers, secondary care and the liver transplant service, synchronised by the transplant coordinator. Managing expectation and balancing the uncertainty of organ availability against the inevitable progression of underlying liver disease requires sensitivity and honesty from all healthcare providers and the assessment of palliative care needs is an integral part of this process.
    Language English
    Publishing date 2020-02-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2521857-8
    ISSN 2041-4137
    ISSN 2041-4137
    DOI 10.1136/flgastro-2019-101215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6880: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Adult liver transplantation: UK clinical guideline - part 2: surgery and post-operation.

    Millson, Charles / Considine, Aisling / Cramp, Matthew E / Holt, Andrew / Hubscher, Stefan / Hutchinson, John / Jones, Kate / Leithead, Joanna / Masson, Steven / Menon, Krish / Mirza, Darius / Neuberger, James / Prasad, Raj / Pratt, Anthony / Prentice, Wendy / Shepherd, Liz / Simpson, Ken / Thorburn, Doug / Westbrook, Rachel /
    Tripathi, Dhiraj

    Frontline gastroenterology

    2020  Volume 11, Issue 5, Page(s) 385–396

    Abstract: Survival rates for patients following liver transplantation exceed 90% at 12 months and approach 70% at 10 years. Part 1 of this guideline has dealt with all aspects of liver transplantation up to the point of placement on the waiting list. Part 2 ... ...

    Abstract Survival rates for patients following liver transplantation exceed 90% at 12 months and approach 70% at 10 years. Part 1 of this guideline has dealt with all aspects of liver transplantation up to the point of placement on the waiting list. Part 2 explains the organ allocation process, organ donation and organ type and how this influences the choice of recipient. After organ allocation, the transplant surgery and the critical early post-operative period are, of necessity, confined to the liver transplant unit. However, patients will eventually return to their referring secondary care centre with a requirement for ongoing supervision. Part 2 of this guideline concerns three key areas of post liver transplantation care for the non-transplant specialist: (1) overseeing immunosuppression, including interactions and adherence; (2) the transplanted organ and how to initiate investigation of organ dysfunction; and (3) careful oversight of other organ systems, including optimising renal function, cardiovascular health and the psychosocial impact. The crucial significance of this holistic approach becomes more obvious as time passes from the transplant, when patients should expect the responsibility for managing the increasing number of non-liver consequences to lie with primary and secondary care.
    Language English
    Publishing date 2020-02-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2521857-8
    ISSN 2041-4137
    ISSN 2041-4137
    DOI 10.1136/flgastro-2019-101216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6880: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis.

    Ghosh, Alok / Pratt, Anthony T / Soma, Shivatheja / Theriault, Sarah G / Griffin, Aaron T / Trivedi, Prachi P / Gohil, Vishal M

    Human molecular genetics

    2016  Volume 25, Issue 4, Page(s) 660–671

    Abstract: Biogenesis of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain, is a complex process facilitated by several assembly factors. Pathogenic mutations were recently reported in one such assembly factor, COA6, and our ... ...

    Abstract Biogenesis of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain, is a complex process facilitated by several assembly factors. Pathogenic mutations were recently reported in one such assembly factor, COA6, and our previous work linked Coa6 function to mitochondrial copper metabolism and expression of Cox2, a copper-containing subunit of CcO. However, the precise role of Coa6 in Cox2 biogenesis remained unknown. Here we show that yeast Coa6 is an orthologue of human COA6, and like Cox2, is regulated by copper availability, further implicating it in copper delivery to Cox2. In order to place Coa6 in the Cox2 copper delivery pathway, we performed a comprehensive genetic epistasis analysis in the yeast Saccharomyces cerevisiae and found that simultaneous deletion of Coa6 and Sco2, a mitochondrial copper metallochaperone, or Coa6 and Cox12/COX6B, a structural subunit of CcO, completely abrogates Cox2 biogenesis. Unlike Coa6 deficient cells, copper supplementation fails to rescue Cox2 levels of these double mutants. Overexpression of Cox12 or Sco proteins partially rescues the coa6Δ phenotype, suggesting their overlapping but non-redundant roles in copper delivery to Cox2. These genetic data are strongly corroborated by biochemical studies demonstrating physical interactions between Coa6, Cox2, Cox12 and Sco proteins. Furthermore, we show that patient mutations in Coa6 disrupt Coa6-Cox2 interaction, providing the biochemical basis for disease pathogenesis. Taken together, these results place COA6 in the copper delivery pathway to CcO and, surprisingly, link it to a previously unidentified function of CcO subunit Cox12 in Cox2 biogenesis.
    MeSH term(s) Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Copper/metabolism ; Cyclooxygenase 2/biosynthesis ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Electron Transport Complex IV/biosynthesis ; Electron Transport Complex IV/genetics ; Electron Transport Complex IV/metabolism ; Humans ; Mitochondria/metabolism ; Mitochondrial Diseases/genetics ; Mitochondrial Diseases/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Mutation ; Phenotype ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
    Chemical Substances Carrier Proteins ; Mitochondrial Proteins ; SCO2 protein, S cerevisiae ; SCO2 protein, human ; Saccharomyces cerevisiae Proteins ; Copper (789U1901C5) ; Cyclooxygenase 2 (EC 1.14.99.1) ; PTGS2 protein, human (EC 1.14.99.1) ; cytochrome C oxidase subunit II (EC 1.9.3.-) ; COX6B1 protein, human (EC 1.9.3.1) ; Electron Transport Complex IV (EC 1.9.3.1)
    Language English
    Publishing date 2016-02-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1108742-0
    ISSN 1460-2083 ; 0964-6906
    ISSN (online) 1460-2083
    ISSN 0964-6906
    DOI 10.1093/hmg/ddv503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Online ; Thesis: On Generalized Signal Waveforms for Satellite Navigation

    Ávila Rodríguez, José Ángel [Verfasser] / Hein, Günter W. [Akademischer Betreuer] / Eissfeller, Bernd [Akademischer Betreuer] / Pratt, Anthony R. [Akademischer Betreuer]

    2008  

    Author's details José Ángel Ávila Rodríguez. Universität der Bundeswehr München, Fakultät für Luft- und Raumfahrttechnik. Gutachter: Günter W. Hein ; Bernd Eissfeller ; Anthony R. Pratt. Betreuer: Günter W. Hein
    Keywords Naturwissenschaften ; Science
    Subject code sg500
    Language English
    Publisher Universitätsbibliothek der Universität der Bundeswehr München
    Publishing place Neubiberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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