LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Preeti Thakur"
  2. AU="Wegmair, Lisa"
  3. AU="Sangpukdee, Aree"
  4. AU="Huang, Sequin"
  5. AU="Robin Kageyama"
  6. AU="Thapa Shrestha, Upendra"
  7. AU="Litvinovskaya, Raisa P"
  8. AU="MacDougall‐Shackleton, Elizabeth A."
  9. AU="Rajendram, Rathie"
  10. AU=Laxminarayan Ramanan
  11. AU="Perriman, Diana M"
  12. AU=Radich Jerald P
  13. AU="Velthuis, Birgitta"
  14. AU="Gibbs, Tom"
  15. AU=Mezzabotta Federica
  16. AU="Jalas, Sören"
  17. AU="Suma, Rache"
  18. AU="Calderón, Alejandro"
  19. AU="Demertzi, Vasiliki"
  20. AU="Leonidov, A"
  21. AU="Luo, Suxin"
  22. AU="Thompson, Charlotte A S"
  23. AU="Dubbel, Polly"
  24. AU="Ten Bosch, Nora"
  25. AU="Giménez-Arnau, Ana Maria"
  26. AU=Maul Robert W.
  27. AU="Ivn Prez-MaldonadoauthorLaboratorio de Toxicologa Molecular, Centro de Investigacin Aplicada en Ambiente y Salud (CIAAS), Coordinacin para la Innovacin y Aplicacin de la Ciencia y la Tecnologa (CIACYT), Universidad Autnoma de San Luis Potos, MexicoFacultad de Medicina, Universidad Autnoma de San Luis Potos, San Luis Potos, MexicoFacultad de Enfermera, Universidad Autnoma de Zacatecas, Mexico"
  28. AU="Hansen, Kristian Schultz"
  29. AU="Davenport, Bennett"

Suchergebnis

Treffer 1 - 10 von insgesamt 15

Suchoptionen

  1. Artikel ; Online: Metagenomics and Whole Genome Sequencing in Clinical Microbiology

    Preeti Thakur / Indira Verma

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 12, Pp 01-

    A Narrative Review

    2023  Band 04

    Abstract: The role of Whole Genome Sequencing (WGS) in clinical microbiology is increasing and is not restricted to molecular epidemiology alone. With the advent of third-generation sequencing technologies, its applications in infectious disease diagnostics have ... ...

    Abstract The role of Whole Genome Sequencing (WGS) in clinical microbiology is increasing and is not restricted to molecular epidemiology alone. With the advent of third-generation sequencing technologies, its applications in infectious disease diagnostics have further expanded to include the direct identification of microorganisms from primary clinical samples, prediction of antimicrobial resistance (including antiviral resistance) by detecting resistance genes, and detection of virulence genes. Untargeted metagenomic sequencing of clinical samples can provide a promising platform for the comprehensive diagnosis of infections. This article outlines the applications and scope of WGS and metagenomic sequencing in routine clinical microbiology, along with the challenges and practical issues in their implementation.
    Schlagwörter bioinformatics ; genomic library ; infectious disease ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  2. Artikel ; Online: False Positive Reaction to VDRL Test with Prozone Phenomenon in a Case of Lepromatous Leprosy

    Rohit Chawla / Preeti Thakur / Atul Mohan Kochhar / Sumeet Singla

    MAMC Journal of Medical Sciences, Vol 8, Iss 2, Pp 158-

    2022  Band 162

    Abstract: Abstract The venereal disease research laboratory (VDRL) test, a nontreponemal test for syphilis, may under a certain set of conditions give false positive results in patients who are not infected with Treponema pallidum. A false positive reaction is ... ...

    Abstract Abstract The venereal disease research laboratory (VDRL) test, a nontreponemal test for syphilis, may under a certain set of conditions give false positive results in patients who are not infected with Treponema pallidum. A false positive reaction is defined as a positive reaction to nontreponemal tests, and a negative reaction to treponemal tests, in the serum of a patient who has no history or clinical evidence of syphilis or other treponematosis. A prozone phenomenon in nontreponemal tests is seen largely with secondary syphilis due to high-titer samples that show nonreactive results unless the specimens are diluted. We report here perhaps the first case of lepromatous leprosy, which had a false positive reaction to the VDRL test with the prozone phenomenon. The case initially presented to the outpatient clinic with complaints of epistaxis with nasal stuffiness. The finding of septal perforation on nasal endoscopy is what led to the initial suspicion of syphilis and the subsequent syphilis workup. It was only when the false positive reaction to VDRL test with the prozone phenomenon was noted that the search for other causes was made, which eventually lead to the diagnosis of lepromatous leprosy.
    Schlagwörter false positive reaction ; lepromatous leprosy ; prozone phenomenon ; venereal disease research laboratory test ; Medicine ; R
    Thema/Rubrik (Code) 150
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel ; Online: Ultrasound Guided Paramedian versus Landmark Guided Midline Technique for Spinal AnaesthesiaA Randomised Clinical Trial

    Anil Kumar / Preeti Thakur / Rama Wason

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 12, Pp UC05-UC

    2020  Band 09

    Abstract: Introduction: Spinal anaesthesia has been traditionally performed using landmark guided technique. Ultrasound helps in identifying the insertion point, depth, as well as angle of the needle advancement by visualisation of the neuraxial structures, thus, ... ...

    Abstract Introduction: Spinal anaesthesia has been traditionally performed using landmark guided technique. Ultrasound helps in identifying the insertion point, depth, as well as angle of the needle advancement by visualisation of the neuraxial structures, thus, increasing the probability of successful dural puncture. Aim: To compare the success rates of dural puncture at first attempt between Preprocedural Ultrasound (PUS) guided paramedian and landmark guided midline approach in spinal anaesthesia. Materials and Methods: This was a randomised clinical study, conducted at a Tertiary Care Hospital during May 2017-December 2018. Patients (n=110) undergoing lower limb orthopaedic surgery were randomly allocated into group US (PUS guided with paramedian approach) and group LM (landmark guided with midline approach), with 55 patients each. Number of attempts and passes, procedure time, any complication, periprocedural pain and patient satisfaction were noted. The correlation between quality of ultrasound view and success rate was also analysed using Fisher’s-exact test. Results: The success rate of dural puncture at first attempt was 89.09% in US group versus 76.36% in LM group, p>0.05. Total number of needle insertion attempts (1.31±0.63 in group LM, 1.11±0.31 in group US, p>0.05) were comparable. Total procedure time was higher (11.96±1.55 minutes) in US group as compared to LM group (3.26±0.68 minutes), p<0.001. Periprocedural pain score was significantly lower in US group with p<0.01. The patient satisfaction score was comparable in the two groups, p>0.05. Correlation between the quality of parasagittal oblique view and success rate of dural puncture was good, p<0.01. Conclusion: PUS guided paramedian approach does not significantly increase the success rate at first attempt as compared to midline landmark guided approach.
    Schlagwörter dural puncture ; parasagittal oblique view ; preprocedural ultrasound ; Medicine ; R
    Thema/Rubrik (Code) 616
    Sprache Englisch
    Erscheinungsdatum 2020-12-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  4. Artikel ; Online: MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

    C. Korin Bullen / Alok K. Singh / Stefanie Krug / Shichun Lun / Preeti Thakur / Geetha Srikrishna / William R. Bishai

    JCI Insight, Vol 8, Iss

    2023  Band 20

    Abstract: Host cytosolic sensing of Mycobacterium tuberculosis (M. tuberculosis) RNA by the RIG-I–like receptor (RLR) family perturbs innate immune control within macrophages; however, a distinct role of MDA5, a member of the RLR family, in M. tuberculosis ... ...

    Abstract Host cytosolic sensing of Mycobacterium tuberculosis (M. tuberculosis) RNA by the RIG-I–like receptor (RLR) family perturbs innate immune control within macrophages; however, a distinct role of MDA5, a member of the RLR family, in M. tuberculosis pathogenesis has yet to be fully elucidated. To further define the role of MDA5 in M. tuberculosis pathogenesis, we evaluated M. tuberculosis intracellular growth and innate immune responses in WT and Mda5–/– macrophages. Transfection of M. tuberculosis RNA strongly induced proinflammatory cytokine production in WT macrophages, which was abrogated in Mda5–/– macrophages. M. tuberculosis infection in macrophages induced MDA5 protein expression, accompanied by an increase in MDA5 activation as assessed by multimer formation. IFN-γ–primed Mda5–/– macrophages effectively contained intracellular M. tuberculosis proliferation to a markedly greater degree than WT macrophages. Further comparisons of WT versus Mda5–/– macrophages revealed that during M. tuberculosis infection MDA5 contributed to IL-1β production and inflammasome activation and that loss of MDA5 led to a substantial increase in autophagy. In the mouse TB model, loss of MDA5 conferred host survival benefits with a concomitant reduction in M. tuberculosis bacillary burden. These data reveal that loss of MDA5 is host protective during M. tuberculosis infection in vitro and in vivo, suggesting that M. tuberculosis exploits MDA5 to subvert immune containment.
    Schlagwörter Immunology ; Infectious disease ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag American Society for Clinical investigation
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  5. Artikel ; Online: Mannitol-fermenting and Tube Coagulase-negative Staphylococcal Isolates

    Preeti Thakur / Charu Nayyar / Vibhor Tak / Karnika Saigal

    Journal of Laboratory Physicians, Vol 9, Iss 01, Pp 065-

    Unraveling the Diagnostic Dilemma

    2017  Band 066

    Schlagwörter Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2017-01-01T00:00:00Z
    Verlag Thieme Medical and Scientific Publishers Pvt. Ltd.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  6. Artikel ; Online: Shigella sonnei Sepsis in an Infant

    Charu Nayyar / Preeti Thakur / Vibhor Tak / Amitabh Singh

    Journal of Clinical and Diagnostic Research, Vol 11, Iss 5, Pp DD01-DD

    A Case Report

    2017  Band 02

    Abstract: Shigella bacteraemia is a complication of gastroenteritis caused by Shigella spp. which occurs mainly in immunocompromised children. Other risk factors may include young malnourished children, patients with chronic disease, post transplant patients etc. ... ...

    Abstract Shigella bacteraemia is a complication of gastroenteritis caused by Shigella spp. which occurs mainly in immunocompromised children. Other risk factors may include young malnourished children, patients with chronic disease, post transplant patients etc. We present a case of six-month-old infant who developed an episode of gastroenteritis caused by Shigella sonnei which was followed by septicaemia. The patient was managed well and he recovered. Shigella sonnei was isolated in both stool as well as blood culture. S.sonnei bacteraemia is a rare condition but we should always be vigilant. Blood cultures as well as stool cultures should be performed in patients presenting with acute febrile gastroenteritis, whether immunocompromised or not. This simple, early and prompt investigation may help in precise diagnosis, which will guide the clinician about appropriate intervention like antibiotic therapy and supportive care.
    Schlagwörter bacteraemia ; diarrhea ; six-month-old ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2017-05-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  7. Artikel ; Online: Stenotrophomonas maltophilia

    Charu Nayyar / Preeti Thakur / Vibhor Tak / Karnika Saigal

    Journal of Clinical and Diagnostic Research, Vol 11, Iss 1, Pp DC08-DC

    An Emerging Pathogen in Paediatric Population

    2017  Band 11

    Abstract: Introduction: Stenotrophomonas maltophilia (formerly Pseudomonas maltophilia/Xanthomonas maltophilia), a Gram- negative, non-fermenting bacillus, is being increasingly recognized as a threatening nosocomial pathogen, associated with significant mortality. ...

    Abstract Introduction: Stenotrophomonas maltophilia (formerly Pseudomonas maltophilia/Xanthomonas maltophilia), a Gram- negative, non-fermenting bacillus, is being increasingly recognized as a threatening nosocomial pathogen, associated with significant mortality. Aim: To determine the prevalence of infection, antimicrobial susceptibility pattern and clinical outcome of S. maltophilia in a paediatric population. Materials and Methods: This was a retrospective study conducted over a period of eight months, i.e., October 2015 to May 2016. All clinical samples received in the microbiology laboratory during the study period were processed using standard microbiological procedures. S. maltophilia isolates were selected. Antibiotic susceptibility was performed for levofloxacin and trimethoprim-sulphamethoxazole by Vitek 2C system (Biomerieux, France). Average length of stay and mortality caused by S. maltophilia infection was compared with age and sex matched controls without S. maltophilia infection. Results: A total of 16,234 clinical specimens were received in the microbiology laboratory in the study period, with 2,734 pathogenic bacteria isolated. A total of 1,339 (1.7% of total isolates) Gram-negative bacteria were isolated, out of which 414 were non-fermenters. Among the non-fermenters, 23 (5.5%) were S. maltophilia. Out of the 23 isolates, 15 (65.2%) were isolated from blood, 4 (17.3%) were isolated from urine and tracheal aspirate each. A total of 91.3% of strains were susceptible and 8.6% were resistant to trimethoprimsulphamethoxazole. Total 80% of strains were sensitive and 20% had intermediate susceptibility for levofloxacin. None of the strains were resistant to levofloxacin. Average length of stay of patients with S. maltophilia infection was found out to be 23.3 days as compared to 44.8 days in controls. The average mortality of patients with S. maltophilia infection was found to be same as that of controls (35.2%). Conclusion: S. maltophilia is becoming an important nosocomial pathogen and its isolation rate is ...
    Schlagwörter gram-negative ; levofloxacin ; trimethoprim-sulphamethoxazole ; Medicine ; R
    Thema/Rubrik (Code) 610 ; 630
    Sprache Englisch
    Erscheinungsdatum 2017-01-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  8. Artikel ; Online: Effectiveness of short-term aerobic exercise program on cardiovascular risk profile in moderate risk adults

    Vijay Pratap Singh / Preeti Thakur / Bidita Khandelwal

    CHRISMED Journal of Health and Research, Vol 2, Iss 1, Pp 38-

    A randomized controlled pilot study

    2015  Band 45

    Abstract: Background: According to World Health Report 2002, cardiovascular diseases (CVDs) will be the largest cause of death and disability by 2020 in India. In 2020, 2.6 million Indians are predicted to die due to coronary heart disease, which constitutes 54.1% ...

    Abstract Background: According to World Health Report 2002, cardiovascular diseases (CVDs) will be the largest cause of death and disability by 2020 in India. In 2020, 2.6 million Indians are predicted to die due to coronary heart disease, which constitutes 54.1% of all CVD deaths. Nearly half of these deaths are likely to occur in young and middle-aged individuals (30-69 years). We undertook this study with objectives to evaluate the cardiovascular risk profile in asymptomatic individuals with moderate risk factors and to understand the effect of the short-term (3 weeks) exercise over cardiovascular risk factors. Materials and Methods: A randomized controlled trial was conducted with a total of 34 subjects comprising of 17 subjects in each group. Subjects underwent biochemical tests like fasting lipid (total cholesterol [TC], triglyceride, high-density lipoproteins [HDLs], low-density lipoproteins [LDLs]) and fasting blood glucose. Other outcome measures were VO 2 max, body mass index and body fat % (BF%). Results: This study suggested that 3 weeks of moderate intensity aerobic training has a beneficial effect in lowering the cardiovascular risk profiles in adults with moderate risk factors. This training reduced TC, improves HDL, reduced LDL and improved aerobic capacity by improving VO 2 max and reducing BF%.
    Schlagwörter Aerobic exercise program ; risk profile ; VO 2 ; Medicine ; R ; Nursing ; RT1-120
    Thema/Rubrik (Code) 796
    Sprache Englisch
    Erscheinungsdatum 2015-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  9. Artikel ; Online: Efficacy of Cow Urine as Plant Growth Enhancer and Antifungal Agent

    Savita Jandaik / Preeti Thakur / Vikas Kumar

    Advances in Agriculture, Vol

    2015  Band 2015

    Abstract: The present study was conducted to determine antifungal activity of three different concentrations (5, 10, and 15%) of cow urine against three fungal pathogens (Fusarium oxysporum, Rhizoctonia solani, and Sclerotium rolfsii) isolated from infected plants ...

    Abstract The present study was conducted to determine antifungal activity of three different concentrations (5, 10, and 15%) of cow urine against three fungal pathogens (Fusarium oxysporum, Rhizoctonia solani, and Sclerotium rolfsii) isolated from infected plants of Methi and Bhindi that showed symptoms of damping off and wilting disease by poison food technique. The extent of growth of test fungi in plates poisoned with cow urine was lesser when compared with the control plates. Among these concentrations cow urine at 15% concentration was most effective. When the three fungal organisms were compared, maximum growth suppression was observed in Fusarium oxysporum (78.57%) at 15% concentration of cow urine followed by Rhizoctonia solani (78.37%) and Sclerotium rolfsii (73.84%). Finally we concluded that the cow urine has antifungal activities and the inhibitory activity can be used in the control of fungi. The nutritional effect of cow urine on plant growth was also tested with Trigonella foenum-graecum (Methi) and Abelmoschus esculentus (Bhindi) plants and the chlorophyll and protein content was also estimated.
    Schlagwörter Agriculture (General) ; S1-972
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2015-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  10. Artikel ; Online: Upper extremity constraint-induced movement therapy in infantile hemiplegia

    Selvam Ramachandran / Preeti Thakur

    Journal of Pediatric Neurosciences, Vol 6, Iss 1, Pp 29-

    2011  Band 31

    Abstract: Infantile hemiplegia is one of the clinical forms of cerebral palsy that refers to impaired motor function of one half of the body owing to contralateral brain damage due to prenatal, perinatal and postnatal causes amongst which vascular lesion is the ... ...

    Abstract Infantile hemiplegia is one of the clinical forms of cerebral palsy that refers to impaired motor function of one half of the body owing to contralateral brain damage due to prenatal, perinatal and postnatal causes amongst which vascular lesion is the most common causative factor. We report here the effects of constraint-induced movement therapy in a five-year-old female child with infantile hemiplegia on improvement of upper extremity motor skills.
    Schlagwörter Constraint-induced movement therapy ; infantile hemiplegia ; shaping ; Pediatrics ; RJ1-570 ; Medicine ; R ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245
    Sprache Englisch
    Erscheinungsdatum 2011-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang