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  1. AU="Prieto, Franklin"
  2. AU="Attwood, Matthew J"
  3. AU=Andellini Martina
  4. AU=Ilfeld Brian M
  5. AU="Manuel de Villena, Fernando Pardo"
  6. AU=Anand B S
  7. AU="Pandeya, Sarbesh R"
  8. AU="Parra Viviane M."
  9. AU="Anetsberger, Daniel"
  10. AU="Novizio, Nunzia"
  11. AU="Elizabeth Sweeney"
  12. AU="Carrigan, M"
  13. AU="Majid T Noghani"
  14. AU="Hanh, Bui Thi Bich"
  15. AU="Hyun Chul Song"
  16. AU="Cottraux, Jean"
  17. AU=Mauro Michael J
  18. AU="Labate, Demetrio"
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  1. Artikel ; Online: Perú un escenario posible para coinfección entre COVID-19 y dengue

    Correa-Prieto, Franklin Rouselbel

    Kasmera 48(1) e48131619

    2020  

    Abstract: Sr. Editor, la infección causada por SARS-Cov-2; llamada por la Organización Mundial de la Salud el 11 febrero del 2020 (1), enfermedad por COVID-19; ha sido declara actualmente como una pandemia por la OMS, afectando en este momento a 184 países, siendo ...

    Abstract Sr. Editor, la infección causada por SARS-Cov-2; llamada por la Organización Mundial de la Salud el 11 febrero del 2020 (1), enfermedad por COVID-19; ha sido declara actualmente como una pandemia por la OMS, afectando en este momento a 184 países, siendo una enfermedad emergente (2,3). Actualmente, hay 1.324.907 infectados con 73.703 decesos en el mundo (3,4). En Latinoamérica han superado 24.544 casos (4); siendo Perú uno de los primeros países latinoamericanos en adoptar medidas de contención a esta pandemia (5,6). Sin embargo, habiendo transcurrido veintidós (22) días de aislamiento social obligatorio, hasta la fecha se ha registrado 2561 casos en el territorio peruano, con 92 decesos, 387 hospitalizados y 89 pacientes en la Unidad de Cuidados Intensivos, con necesidad de ventilación mecánica (7). En la zona norte del país, se registra una creciente de los casos, como en los departamentos de Loreto, Piura y Tumbes (7); que además epidemiológicamente son endémicas para dengue, registrándose 4054 casos confirmados de dengue hasta la semana epidemiológica número cuatro, con 10 defunciones (8). Síntomas como fiebre, cefalea, dolor abdominal (9), son presentadas en ambas enfermedades (10); incluido lo que se consideraba característico del Dengue: la erupción maculo-papular (11), ha sido reportado en enfermedad por COVID-19. Además, los hallazgos laboratoriales son similares, pudiendo presentarse en ambas enfermedades: leucopenia, alteración de enzimas hepáticas y plaquetopenia. No obstante, se ha reportado la enfermedad por COVID-19 puede generar un falso positivo en el cribado para dengue (12), lo que implicaría, que los pacientes con sospecha de dengue, y con un falso positivo, sean estratificados como dengue sin signos de alarma y manejados de forma ambulatoria, permitiendo la propagación de la enfermedad por COVID-19, es en este punto donde radica la importancia de su similitud clínica. Además, el personal de Salud que maneja los pacientes con dengue, tiene un equipo de protección personal muy distinto al que se necesita para manejar pacientes con enfermedad por COVID-19. Se debe considerar que coinfecciones como las ya reportadas en Tailandia (13), tienen progresiones de espectro de gravedad de la enfermedad, a letalidad. A esto pueden sumarse, las comorbilidades que se han asociado a un espectro crítico y mortalidad, de las cuales la población peruana en los últimos años esta aumentando sus índices, siendo: enfermedades cardiovasculares, diabetes mellitus y cáncer (14). Hasta la fecha, a nivel de Latinoamérica, y en Perú no se ha reportado una coinfección entre el dengue y enfermedad por COVID-19; sin embargo, es importante que se enfoquen y dirijan medidas a estos escenarios eventuales y se desarrollen políticas de salud pública que permitan su prevención, y el desarrollo de protocolos de atención de estos probables escenarios clínicos, no contemplados en la normativa sanitaria vigente (15)
    Schlagwörter covid19
    Sprache Spanisch
    Erscheinungsdatum 2020-04-07
    Erscheinungsland eu
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel: [Geographic distribution of perinatal mortality due to congenital malformations in Colombia, 1999-2008: An analysis of vital statistics data].

    Misnaza, Sandra Patricia / Roncancio, Claudia Patricia / Peña, Isabel Cristina / Prieto, Franklin Edwin

    Biomedica : revista del Instituto Nacional de Salud

    2016  Band 36, Heft 3, Seite(n) 359–367

    Abstract: Introduction: During 2012, 13% of the deaths worldwide in children under the age of 28 days were due to congenital malformations. In Colombia, congenital malformations are the second leading cause of infant mortality. Objective: To determine the ... ...

    Abstract Introduction: During 2012, 13% of the deaths worldwide in children under the age of 28 days were due to congenital malformations. In Colombia, congenital malformations are the second leading cause of infant mortality. Objective: To determine the geographical distribution of extended perinatal mortality due to congenital malformations in Colombia between 1999 and 2008. Materials and methods: We conducted a cross-sectional study. We revised all death certificates issued between 1999 and 2008. We defined perinatal mortality as fetal or non-fetal deaths within the first 28 days after delivery in children with body weight ≥500 grams, and congenital malformations according to ICD-10 diagnostic codes Q000 - Q999. The annual birth projection was used as the denominator. We defined high mortality areas due to congenital malformations as those in the 90th percentile. Results: We recorded 22,361 perinatal deaths due to congenital malformations. The following provinces exceeded the 90th perinatal mortality percentile: Antioquia, Caldas, Risaralda, Huila, Quindío, Bogotá, Valle del Cauca and Guainía. Among the municipalities, the highest perinatal mortality rates were found in Giraldo, Ciudad Bolívar, Riosucio, Liborina, Supía, Alejandría, Sopetrán, San Jerónimo, Santa Fe de Antioquia and Marmato (205.81 and 74.18 per 10.000 live births).The perinatal mortality rate due to malformations of the circulatory system was 28.1 per 10.000 live births, whereas the rates for central nervous system defects and chromosomal abnormalities were 13.7 and 7.0, respectively.
    Conclusions: The Andean region showed high perinatal mortality rates due to congenital malformations. There is an urgent need to identify possible risk factors of perinatal mortality and implement successive prevention programs in that particular region.
    Sprache Spanisch
    Erscheinungsdatum 2016-09-01
    Erscheinungsland Colombia
    Dokumenttyp Journal Article ; English Abstract
    ISSN 0120-4157
    ISSN 0120-4157
    DOI 10.7705/biomedica.v36i3.2867
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: [Titelangabe fehlt]

    Cala, Dorian Yisela / Falla, Jesús Dávida / Montalvo, Carlos Andrés / Misnaza, Sandra Patricia / Roncancio, Claudia Patricia / Peña, Isabel Cristina / Prieto, Franklin Edwin

    Biomedica : revista del Instituto Nacional de Salud

    2016  Band 36, Heft 3, Seite(n) 487–488

    Titelübersetzung Carta al editor "Áreas de alta mortalidad perinatal debida a anomalías congénitas: análisis de estadísticas vitales, Colombia, 1999-2008".
    Sprache Englisch
    Erscheinungsdatum 2016-09-01
    Erscheinungsland Colombia
    Dokumenttyp Journal Article
    ISSN 0120-4157
    ISSN 0120-4157
    DOI 10.7705/biomedica.v36i3.3619
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2, Colombia.

    Laiton-Donato, Katherine / Villabona-Arenas, Christian Julián / Usme-Ciro, José A / Franco-Muñoz, Carlos / Álvarez-Díaz, Diego A / Villabona-Arenas, Liz Stephany / Echeverría-Londoño, Susy / Cucunubá, Zulma M / Franco-Sierra, Nicolás D / Flórez, Astrid C / Ferro, Carolina / Ajami, Nadim J / Walteros, Diana Marcela / Prieto, Franklin / Durán, Carlos Andrés / Ospina-Martínez, Martha Lucia / Mercado-Reyes, Marcela

    Emerging infectious diseases

    2020  Band 26, Heft 12, Seite(n) 2854–2862

    Abstract: Coronavirus disease (COVID-19) in Colombia was first diagnosed in a traveler arriving from Italy on February 26, 2020. However, limited data are available on the origins and number of introductions of COVID-19 into the country. We sequenced the causative ...

    Abstract Coronavirus disease (COVID-19) in Colombia was first diagnosed in a traveler arriving from Italy on February 26, 2020. However, limited data are available on the origins and number of introductions of COVID-19 into the country. We sequenced the causative agent of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), from 43 clinical samples we collected, along with another 79 genome sequences available from Colombia. We investigated the emergence and importation routes for SARS-CoV-2 into Colombia by using epidemiologic, historical air travel, and phylogenetic observations. Our study provides evidence of multiple introductions, mostly from Europe, and documents >12 lineages. Phylogenetic findings validate the lineage diversity, support multiple importation events, and demonstrate the evolutionary relationship of epidemiologically linked transmission chains. Our results reconstruct the early evolutionary history of SARS-CoV-2 in Colombia and highlight the advantages of genome sequencing to complement COVID-19 outbreak investigations.
    Mesh-Begriff(e) COVID-19/epidemiology ; COVID-19/virology ; Colombia/epidemiology ; Genome, Viral ; Genomics/methods ; Humans ; Phylogeny ; Reproducibility of Results ; SARS-CoV-2/genetics
    Sprache Englisch
    Erscheinungsdatum 2020-11-20
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2612.202969
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Case-Case Comparison of Candida auris Versus Other Candida Species Bloodstream Infections: Results of an Outbreak Investigation in Colombia.

    Caceres, Diego H / Rivera, Sandra M / Armstrong, Paige A / Escandon, Patricia / Chow, Nancy A / Ovalle, Maria Victoria / Díaz, Jorge / Derado, Gordana / Salcedo, Soraya / Berrio, Indira / Espinosa-Bode, Andres / Varón, Carmen / Stuckey, Matthew J / Mariño, Adriana / Villalobos, Nohora / Lockhart, Shawn R / Chiller, Tom M / Prieto, Franklin E / Jackson, Brendan R

    Mycopathologia

    2020  Band 185, Heft 5, Seite(n) 917–923

    Abstract: Background: Candida auris is an emerging multidrug-resistant yeast that causes outbreaks in healthcare settings around the world. In 2016, clinicians and public health officials identified patients with C. auris bloodstream infections (BSI) in Colombian ...

    Abstract Background: Candida auris is an emerging multidrug-resistant yeast that causes outbreaks in healthcare settings around the world. In 2016, clinicians and public health officials identified patients with C. auris bloodstream infections (BSI) in Colombian healthcare facilities. To evaluate potential risk factors and outcomes for these infections, we investigated epidemiologic and clinical features of patients with C. auris and other Candida species BSI.
    Methods: We performed a retrospective case-case investigation in four Colombian acute care hospitals, defining a case as Candida spp. isolated from blood culture during January 2015-September 2016. C. auris BSI cases were compared to other Candida species BSI cases. Odds ratio (OR), estimated using logistic regression, was used to assess the association between risk factors and outcomes.
    Results: We analyzed 90 patients with BSI, including 40 with C. auris and 50 with other Candida species. All had been admitted to the intensive care unit (ICU). No significant demographic differences existed between the two groups. The following variables were independently associated with C. auris BSI: ≥ 15 days of pre-infection ICU stay (OR: 5.62, CI: 2.04-15.5), evidence of severe sepsis (OR: 3.70, CI 1.19-11.48), and diabetes mellitus (OR 5.69, CI 1.01-31.9).
    Conclusion: Patients with C. auris BSI had longer lengths of ICU stay than those with other candidemias, suggesting that infections are acquired during hospitalization. This is different from other Candida infections, which are usually thought to result from autoinfection with host flora.
    Mesh-Begriff(e) Adult ; Antifungal Agents/therapeutic use ; Candida/isolation & purification ; Candidemia/diagnosis ; Candidemia/drug therapy ; Candidemia/epidemiology ; Candidiasis/diagnosis ; Candidiasis/drug therapy ; Candidiasis/epidemiology ; Colombia/epidemiology ; Cross Infection/diagnosis ; Cross Infection/epidemiology ; Diabetes Complications/microbiology ; Diagnosis, Differential ; Disease Outbreaks ; Female ; Humans ; Infection Control ; Intensive Care Units ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sepsis/complications ; Sepsis/microbiology ; Treatment Outcome ; Young Adult
    Chemische Substanzen Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2020-08-29
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 391081-7
    ISSN 1573-0832 ; 0369-299X ; 0301-486X ; 0027-5530
    ISSN (online) 1573-0832
    ISSN 0369-299X ; 0301-486X ; 0027-5530
    DOI 10.1007/s11046-020-00478-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2

    Laiton-Donato, Katherine / Franco-Munoz, Carlos / Alvarez-Diaz, Diego Alejandro / Ruiz-Moreno, Hector / Usme-Ciro, Jose / Prada, Diego / Reales, Jhonnatan / Corchuelo, Sheryll / Herrera-sepulveda, Maria / Naizaque, Julian / Santamaria, Gerardo / Rivera, Jorge / Rojas, Paola / Cardona Rios, Andres / Hernandez-Ortiz, Juan / Malo, Diana / Prieto, Franklin / Ruiz-Gomez, Fernando / Wiesner, Magdalena /
    Ospina-Martinez, Martha Lucia / Mercado-Reyes, Marcela

    medRxiv

    Abstract: The SARS-CoV-2 genetic diversification has a potential impact in the virus escape from natural infection- or vaccine-elicited neutralizing antibodies and higher transmissibility. Here we report the emergence of novel B.1.621 variant of interest with the ... ...

    Abstract The SARS-CoV-2 genetic diversification has a potential impact in the virus escape from natural infection- or vaccine-elicited neutralizing antibodies and higher transmissibility. Here we report the emergence of novel B.1.621 variant of interest with the insertion 145N in the N-terminal domain and amino acid change N501Y, E484K, and P681H in the Receptor Binding Domain of the Spike protein. Further studies in vitro biological assays and epidemiologic analysis will allow evaluating the public health impact of B.1.621 variant.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2021-05-10
    Verlag Cold Spring Harbor Laboratory Press
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2021.05.08.21256619
    Datenquelle COVID19

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  7. Artikel: Situación de las enfermedades de transmisión sexual, Colombia, 1976-2000.

    Acosta, Jacqueline / Prieto, Franklin / Rodríguez, David / Rueda, Carlos

    Biomedica : revista del Instituto Nacional de Salud

    2002  Band 22, Heft 1, Seite(n) 77–88

    Titelübersetzung The status of sexually transmitted diseases, Colombia, 1976-2000.
    Mesh-Begriff(e) Acquired Immunodeficiency Syndrome/epidemiology ; Acquired Immunodeficiency Syndrome/mortality ; Acquired Immunodeficiency Syndrome/transmission ; Age Distribution ; Anti-HIV Agents/therapeutic use ; Colombia/epidemiology ; Female ; HIV Infections/epidemiology ; HIV Infections/mortality ; HIV Infections/transmission ; Health Knowledge, Attitudes, Practice ; Health Surveys ; Hepatitis B/epidemiology ; Humans ; Male ; Prevalence ; Prisons/statistics & numerical data ; Sex Distribution ; Sexual Behavior ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/mortality ; Syphilis, Congenital/epidemiology ; Transfusion Reaction
    Chemische Substanzen Anti-HIV Agents
    Sprache Spanisch
    Erscheinungsdatum 2002-03
    Erscheinungsland Colombia
    Dokumenttyp Journal Article
    ISSN 0120-4157
    ISSN 0120-4157
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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