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  1. Book ; Online: Neurology of Covid-19

    Priori, Alberto

    2021  

    Keywords Neurology & clinical neurophysiology ; Covid-19 ; Neurology ; Neurology of Covid-19 ; neuroimaging of Covid-19 ; Neuropathology of Covid-19 ; pathophysiology of Covid-19 ; pediatric Covid -19 ; neurophysiology of Covid-19 ; epilepsy of Covid-19 ; seizures of Covid-19 ; EEG of Covid-19 ; Psychiatry and psycology of Covid-19 ; Brainsystem and Covid-19
    Language 0|e
    Size 1 electronic resource (330 pages)
    Publisher Milano University Press
    Publishing place Milano
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021615508
    ISBN 979-12-80325-33-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Abracadabra. Il potere curativo delle parole tra mito, tradizioni e neuroscienze

    Muntoni, Cristina / Priori, Alberto

    2022  

    Keywords Sociology & anthropology ; word ; writing ; reading ; language ; cognition
    Language 0|i
    Size 1 Online-Ressource
    Publisher Milano University Press
    Publishing place Milano
    Document type Book ; Online
    Note Italian ; Open Access
    HBZ-ID HT021621872
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Towards chronic non-invasive stimulation: what can you learn from pain research?

    Bocci, Tommaso / Priori, Alberto

    Brain communications

    2023  Volume 5, Issue 4, Page(s) fcad193

    Abstract: This scientific commentary refers to 'Long-term analgesic effect of trans-spinal direct current stimulation compared to non-invasive motor cortex stimulation in complex regional pain syndrome, by ... ...

    Abstract This scientific commentary refers to 'Long-term analgesic effect of trans-spinal direct current stimulation compared to non-invasive motor cortex stimulation in complex regional pain syndrome, by Hodaj
    Language English
    Publishing date 2023-07-05
    Publishing country England
    Document type Journal Article
    ISSN 2632-1297
    ISSN (online) 2632-1297
    DOI 10.1093/braincomms/fcad193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: The frontiers of clinical research on transcranial direct current stimulation (tDCS) in Neuropsychiatry

    Ferrucci, Roberta / Boggio, Paulo S. / Fregni, Felipe / Brunoni, Andre R. / Priori, Alberto

    2015  

    Abstract: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation intervention that induces changes in cortical activity and excitability according to the parameters of stimulation. TDCS effects have been reported since the 1800s with ... ...

    Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation intervention that induces changes in cortical activity and excitability according to the parameters of stimulation. TDCS effects have been reported since the 1800s with the development of the galvanic cell, although more systematic research has been conducted only from 1950-1970 and then from 1998 onwards. At the present time, most tDCS studies have been conducted in healthy volunteers, proving the properties of tDCS as a technique that induces long-lasting, polarity-dependent changes on specific brain areas. In addition, some studies have applied tDCS in selected neuropsychiatric samples, as to investigate its therapeutic effects, obtaining mixed albeit mostly positive results.-

    Using tDCS in clinical practice could bring enormous gains for the treatment of several neuropsychiatric disorders, as tDCS is a portable, non-expensive and straightforward therapy, being therefore a putative candidate as an add-on or substitutive therapy for pharmacological treatments. However, there is still a gap between tDCS basic and clinical research, as it is still unknown whether and how the potent neuromodulatory effects observed after one tDCS session can be carried over for several weeks; therefore proving that tDCS is also a reliable clinical tool. In addition, another gap is observed in tDCS translational research, as results obtained from experimental animal models might not be fully generalizable to neuropsychiatric disorders in humans. Thus, advancing basic and experimental tDCS research as well as tailoring the optimal parameters of stimulation represents the frontiers of tDCS use in neuropsychiatry.-

    In this special edition, our aim is to gather studies that contribute to the proposal of using tDCS for the treatment and investigation of neuropsychiatric disorders. Desired studies include (but are not limited to) the following topics: (1) clinical trials using tDCS as a treatment for neuropsychiatric disorders. (2) original studies investigating optimal parameters for daily tDCS stimulation. (3) safety and tolerability of tDCS, including reports of unexpected and serious adverse effects. (4) comprehensive reviews of putative mechanisms of action of tDCS for neuropsychiatric disorders. (5) translational research, testing different protocols of stimulation in experimental animals. (6) modeling tDCS studies, including studies testing different tDCS devices and montages. (7) studies of cost-efficacy analysis. (8) development of appropriate study designs for tDCS. (9) development of novel employments of tDCS, such as portable, safe devices that allow domestic utilization.-
    Keywords Psychiatry ; Medicine (General)
    Size 1 electronic resource (210 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090210
    ISBN 9782889192878 ; 2889192873
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Reply to the letter "SARS-CoV-2 cannot unmask Parkinson's disease if there was none before infection".

    Calculli, Alessandra / Bocci, Tommaso / Priori, Alberto / Pisani, Antonio

    European journal of neurology

    2023  Volume 30, Issue 9, Page(s) 2948

    MeSH term(s) Humans ; SARS-CoV-2 ; Parkinson Disease ; COVID-19
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4738: Show issues Location:
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    Zs.MO 592: Show issues

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  6. Article ; Online: Future directions in the pathophysiological assessment of focal and generalized dystonias.

    Bocci, Tommaso / Priori, Alberto

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2021  Volume 132, Issue 12, Page(s) 3179–3180

    MeSH term(s) Dystonia ; Dystonic Disorders ; Humans
    Language English
    Publishing date 2021-09-27
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2021.09.002
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  7. Article: Amplitude and frequency modulation of subthalamic beta oscillations jointly encode the dopaminergic state in Parkinson's disease.

    Averna, Alberto / Marceglia, Sara / Priori, Alberto / Foffani, Guglielmo

    NPJ Parkinson's disease

    2022  Volume 8, Issue 1, Page(s) 131

    Abstract: Brain states in health and disease are classically defined by the power or the spontaneous amplitude modulation (AM) of neuronal oscillations in specific frequency bands. Conversely, the possible role of the spontaneous frequency modulation (FM) in ... ...

    Abstract Brain states in health and disease are classically defined by the power or the spontaneous amplitude modulation (AM) of neuronal oscillations in specific frequency bands. Conversely, the possible role of the spontaneous frequency modulation (FM) in defining pathophysiological brain states remains unclear. As a paradigmatic example of pathophysiological resting states, here we assessed the spontaneous AM and FM dynamics of subthalamic beta oscillations recorded in patients with Parkinson's disease before and after levodopa administration. Even though AM and FM are mathematically independent, they displayed negatively correlated dynamics. First, AM decreased while FM increased with levodopa. Second, instantaneous amplitude and instantaneous frequency were negatively cross-correlated within dopaminergic states, with FM following AM by approximately one beta cycle. Third, AM and FM changes were also negatively correlated between dopaminergic states. Both the slow component of the FM and the fast component (i.e. the phase slips) increased after levodopa, but they differently contributed to the AM-FM correlations within and between states. Finally, AM and FM provided information about whether the patients were OFF vs. ON levodopa, with partial redundancy and with FM being more informative than AM. AM and FM of spontaneous beta oscillations can thus both separately and jointly encode the dopaminergic state in patients with Parkinson's disease. These results suggest that resting brain states are defined not only by AM dynamics but also, and possibly more prominently, by FM dynamics of neuronal oscillations.
    Language English
    Publishing date 2022-10-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819218-7
    ISSN 2373-8057
    ISSN 2373-8057
    DOI 10.1038/s41531-022-00399-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Movement disorders and neuropathies: overlaps and mimics in clinical practice.

    Gentile, Francesco / Bertini, Alessandro / Priori, Alberto / Bocci, Tommaso

    Journal of neurology

    2022  Volume 269, Issue 9, Page(s) 4646–4662

    Abstract: Movement disorders as well as peripheral neuropathies are extremely frequent in the general population; therefore, it is not uncommon to encounter patients with both these conditions. Often, the coexistence is coincidental, due to the high incidence of ... ...

    Abstract Movement disorders as well as peripheral neuropathies are extremely frequent in the general population; therefore, it is not uncommon to encounter patients with both these conditions. Often, the coexistence is coincidental, due to the high incidence of common causes of peripheral neuropathy, such as diabetes and other age-related disorders, as well as of Parkinson disease (PD), which has a typical late onset. Nonetheless, there is broad evidence that PD patients may commonly develop a sensory and/or autonomic polyneuropathy, triggered by intrinsic and/or extrinsic mechanisms. Similarly, some peripheral neuropathies may develop some movement disorders in the long run, such as tremor, and rarely dystonia and myoclonus, suggesting that central mechanisms may ensue in the pathogenesis of these diseases. Although rare, several acquired or hereditary causes may be responsible for the combination of movement and peripheral nerve disorders as a unique entity, some of which are potentially treatable, including paraneoplastic, autoimmune and nutritional aetiologies. Finally, genetic causes should be pursued in case of positive family history, young onset or multisystemic involvement, and examined for neuroacanthocytosis, spinocerebellar ataxias, mitochondrial disorders and less common causes of adult-onset cerebellar ataxias and spastic paraparesis. Deep phenotyping in terms of neurological and general examination, as well as laboratory tests, neuroimaging, neurophysiology, and next-generation genetic analysis, may guide the clinician toward the correct diagnosis and management.
    MeSH term(s) Adult ; Dystonia ; Humans ; Parkinson Disease/complications ; Parkinson Disease/diagnosis ; Parkinson Disease/genetics ; Peripheral Nervous System Diseases/diagnosis ; Spinocerebellar Ataxias/genetics ; Tremor
    Language English
    Publishing date 2022-06-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-022-11200-0
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  9. Article ; Online: Neurology of cancer immunotherapy.

    De Grado, Amedeo / Cencini, Federica / Priori, Alberto

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2022  

    Abstract: Background: Immunotherapy is nowadays considered a mainstay of cancer treatment, dramatically affecting the disease-free survival rate in several aggressive malignancies. Unfortunately, cancer immunotherapy can also trigger life-threatening autoimmune ... ...

    Abstract Background: Immunotherapy is nowadays considered a mainstay of cancer treatment, dramatically affecting the disease-free survival rate in several aggressive malignancies. Unfortunately, cancer immunotherapy can also trigger life-threatening autoimmune neurological complications named "neurological adverse effects" (NAEs). NAEs can affect both the central nervous system (CNS), as in ipilimumab-related aseptic meningitis, and the peripheral nervous system (PNS), as in nivolumab-induced myasthenia gravis.
    Current evidence: The incidence of NAEs is highly variable, ranging from 2 to 4% using checkpoint inhibitors to 50% using blinatumomab. Looking at these numbers, it appears clear that neurologists will soon be called more and more frequently to decide upon the best therapeutic strategy for a patient receiving immunotherapy and experiencing a NAE. Most of them can be treated or reverted withholding the offending drug and adding IVIg, plasmapheresis, or steroids to the therapy. Sometimes, however, for oncological reasons, immunotherapy cannot be stopped so the neurologist needs to know what countermeasures have proven most effective. Moreover, patients with a pre-existing autoimmune neurological disease (AID), such as myasthenia gravis or multiple sclerosis, might need immunotherapy during their life, risking a severe worsening of their symptoms. In that setting, the neurologist needs to properly counsel patients about the risk of a therapy-related relapse.
    Conclusion: In this article, we describe the most frequently reported NAEs and aim to give neurologists a practical overview on how to deal with them.
    Language English
    Publishing date 2022-09-16
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-06297-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Technology for deep brain stimulation at a gallop.

    Priori, Alberto

    Movement disorders : official journal of the Movement Disorder Society

    2015  Volume 30, Issue 9, Page(s) 1206–1212

    MeSH term(s) Antiparkinson Agents/therapeutic use ; Deep Brain Stimulation/methods ; Deep Brain Stimulation/trends ; Electroencephalography ; Electromyography ; Evoked Potentials/physiology ; Humans ; Male ; Middle Aged ; Parkinson Disease/physiopathology ; Parkinson Disease/therapy ; Severity of Illness Index
    Chemical Substances Antiparkinson Agents
    Language English
    Publishing date 2015-08
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.26253
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    Zs.MO 238: Show issues

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