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  1. Article ; Online: Waveform Plasticity under Entrainment to 12-h

    Abhilash, Lakshman / Ramakrishnan, Aishwarya / Priya, Srishti / Sheeba, Vasu

    Journal of biological rhythms

    2020  Volume 35, Issue 2, Page(s) 145–157

    Abstract: A crucial property of circadian clocks is the ability to regulate the shape of an oscillation over its cycle length (waveform) appropriately, thus enhancing Darwinian fitness. Many studies over the past decade have revealed interesting ways in which the ... ...

    Abstract A crucial property of circadian clocks is the ability to regulate the shape of an oscillation over its cycle length (waveform) appropriately, thus enhancing Darwinian fitness. Many studies over the past decade have revealed interesting ways in which the waveform of rodent behavior could be manipulated, one of which is that the activity bout bifurcates under environments that have 2 light/dark cycles within one 24-h day (LDLD). It has been observed that such unique, although unnatural, environments reveal acute changes in the circadian clock network. However, although adaptation of waveforms to different photoperiods is well studied, modulation of waveforms under LDLD has received relatively less attention in research on insect rhythms. Therefore, we undertook this study to ask the following questions: what is the extent of waveform plasticity that
    MeSH term(s) Animals ; Behavior, Animal ; Circadian Clocks/genetics ; Circadian Rhythm ; Drosophila melanogaster/genetics ; Drosophila melanogaster/physiology ; Evolution, Molecular ; Female ; Male ; Movement/radiation effects ; Nerve Net ; Neuronal Plasticity ; Neurons/physiology ; Photoperiod
    Language English
    Publishing date 2020-01-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 896387-3
    ISSN 1552-4531 ; 0748-7304
    ISSN (online) 1552-4531
    ISSN 0748-7304
    DOI 10.1177/0748730419899549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A potential screening method for epigenetic drugs: uncovering stress-induced gene silencing in

    Kaginkar, Snehal / Priya, Srishti / Sharma, Upnishad / D'Souza, Jacinta S / Sen, Subhojit

    Free radical research

    2021  Volume 55, Issue 5, Page(s) 533–546

    Abstract: Histone modifications and DNA methylation together govern promoter availability, thereby influencing gene expression. This study queries the unicellular chlorophyte, ...

    Abstract Histone modifications and DNA methylation together govern promoter availability, thereby influencing gene expression. This study queries the unicellular chlorophyte,
    MeSH term(s) Animals ; Chlamydomonas/genetics ; Epigenomics/methods ; Gene Silencing/immunology ; Mass Screening
    Language English
    Publishing date 2021-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1194130-3
    ISSN 1029-2470 ; 1071-5762
    ISSN (online) 1029-2470
    ISSN 1071-5762
    DOI 10.1080/10715762.2021.1876231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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