Article ; Online: Computed tomography pulmonary angiography in acute pulmonary embolism: the effect of a computer-assisted detection prototype used as a concurrent reader.
2013 Volume 28, Issue 5, Page(s) 315–321
Abstract: Purpose: To assess the effect of computer-assisted detection (CAD) on diagnostic accuracy, reader confidence, and reading time when used as a concurrent reader for the detection of acute pulmonary embolism in computed tomography pulmonary angiography.!## ...
| Abstract | Purpose: To assess the effect of computer-assisted detection (CAD) on diagnostic accuracy, reader confidence, and reading time when used as a concurrent reader for the detection of acute pulmonary embolism in computed tomography pulmonary angiography. Materials and methods: In this institutional review board-approved retrospective study, 6 observers with varying experience evaluated 158 negative and 38 positive consecutive computed tomography pulmonary angiographies (mean patient age 60 y; 115 women) without and with CAD as a concurrent reader. Readers were asked to determine the presence of pulmonary embolism, assess their diagnostic confidence using a 5-point scale, and document their reading time. Results were compared with an independent standard established by 2 readers, and a third chest radiologist was consulted in case of discordant findings. Results: Using logistic regression for repeated measurements, we found a significant increase in readers' sensitivity (P<0.001) without loss of specificity (P=0.855) with the effects being reader dependent (P<0.001). Sensitivities varied from 68% to 100% without CAD and from 76% to 100% with CAD. A 2-way analysis of variance showed a small but significant decrease in reading time (P<0.001), with the duration varying between 24 and 208 seconds without CAD and between 17 and 196 seconds with CAD, and a significant increase in readers' confidence scores using CAD as a concurrent reader (P<0.001). Conclusions: CAD as a concurrent reader has the potential to increase readers' sensitivity and confidence with a decrease in reading time without loss of specificity. The differences between readers, however, require further evaluation of CAD as a concurrent reader in a larger trial before stronger conclusions can be drawn. |
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| MeSH term(s) | Acute Disease ; Angiography ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Pulmonary Embolism/diagnostic imaging ; Radiographic Image Interpretation, Computer-Assisted/methods ; Retrospective Studies ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods | |||||
| Language | English | |||||
| Publishing date | 2013-09 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 632900-7 | |||||
| ISSN | 1536-0237 ; 0883-5993 | |||||
| ISSN (online) | 1536-0237 | |||||
| ISSN | 0883-5993 | |||||
| DOI | 10.1097/RTI.0b013e3182870b97 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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