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  1. Article ; Online: Personalized Dual Antiplatelet Therapy in Acute Coronary Syndromes: Striking a Balance Between Bleeding and Thrombosis.

    Shpigelman, Jonathan / Proshkina, Anastasia / Daly, Michael J / Cox, Dermot

    Current cardiology reports

    2023  Volume 25, Issue 7, Page(s) 693–710

    Abstract: Purpose of review: Dual antiplatelet therapy (DAPT)-aspirin in conjunction with a P2Y: Recent findings: The potent ... ...

    Abstract Purpose of review: Dual antiplatelet therapy (DAPT)-aspirin in conjunction with a P2Y
    Recent findings: The potent P2Y
    MeSH term(s) Humans ; Platelet Aggregation Inhibitors/adverse effects ; Acute Coronary Syndrome/drug therapy ; Purinergic P2Y Receptor Antagonists/therapeutic use ; Purinergic P2Y Receptor Antagonists/adverse effects ; Drug Therapy, Combination ; Aspirin/therapeutic use ; Hemorrhage/drug therapy ; Thrombosis/drug therapy ; Thrombosis/prevention & control ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome
    Chemical Substances Platelet Aggregation Inhibitors ; Purinergic P2Y Receptor Antagonists ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2055373-0
    ISSN 1534-3170 ; 1523-3782
    ISSN (online) 1534-3170
    ISSN 1523-3782
    DOI 10.1007/s11886-023-01892-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5524: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Time to ECG diagnosis delays inter-hospital transfer to revascularization in STEMI patients presenting to a regional emergency department: a five-year audit.

    Shpigelman, Jonathan / Proshkina, Anastasia / Roman, Marin / Maleady, Ken / Casserly, Ivan / Blake, Gavin / O'Boyle, Patrick / Saiva, Lavanya / Keelan, Edward / O'Neill, James / Daly, Michael

    Irish journal of medical science

    2024  

    Abstract: Background: Reducing the door-to-balloon time (D2BT) in ST-elevation myocardial infarction (STEMI) patients maximizes myocardial salvage and mitigates morbidity/mortality.: Aims: To assess the D2BT in STEMI patients requiring inter-hospital transfer ... ...

    Abstract Background: Reducing the door-to-balloon time (D2BT) in ST-elevation myocardial infarction (STEMI) patients maximizes myocardial salvage and mitigates morbidity/mortality.
    Aims: To assess the D2BT in STEMI patients requiring inter-hospital transfer for revascularization and identify any potential causes of delay.
    Methods: Consecutive patients presenting to the Connolly Hospital Blanchardstown (CHB) emergency department (ED) who were transferred to the Mater Misericordiae University Hospital in Dublin for primary percutaneous coronary intervention from January 2018 to October 2022 were identified in a regional database and their D2BTs calculated. D2BTs were further sub-categorized into key intervals to identify any potential causes of delay.
    Results: A total of 90 patients were included for analysis, with a median D2BT of 117.5 min (interquartile range [IQR]: 99.3-170.8 min) and 52.5% of patients achieving the ≤ 120 min target. Despite being the shortest interval considered, the time from arrival at the CHB ED to diagnostic electrocardiogram (ECG) was a substantial contributor to the overall delay to revascularization given its wide variability (median: 18.0 min; IQR: 9.0-46.8 min), with only 28.8% of patients achieving the ≤ 10 min target.
    Conclusions: Nearly half of the patients studied failed to achieve the overall target D2BT for revascularization. The time from arrival at the CHB ED to diagnostic ECG was identified as a substantial contributor to this failure, with a median time almost twice that of the target and a quarter of all patients spending longer than 46.8 min. These findings highlight a need to improve the implementation of ECG triage and interpretation in the ED.
    Language English
    Publishing date 2024-05-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-024-03705-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 323: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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