Article ; Online: Dark Blood Contrast-Enhanced Brain MRI Using Echo-uT
Journal of magnetic resonance imaging : JMRI
2023
Abstract: Background: The widely used magnetization-prepared rapid gradient-echo (MPRAGE) sequence makes enhancing lesions and blood vessels appear bright after gadolinium administration. However, dark blood imaging using T1-weighted Sampling Perfection with ... ...
Abstract | Background: The widely used magnetization-prepared rapid gradient-echo (MPRAGE) sequence makes enhancing lesions and blood vessels appear bright after gadolinium administration. However, dark blood imaging using T1-weighted Sampling Perfection with Application optimized Contrast using different flip angle Evolution (T1 SPACE) can be advantageous since it improves the conspicuity of small metastases and leptomeningeal disease. As a potential alternative to T1 SPACE, we evaluated a new dark blood sequence called echo-uT Purpose: We compared the performance of echo-uT Study type: Retrospective, IRB approved. Subjects/phantom: Phantom to assess flow properties of echo-uT Field strength/sequences: 3 Tesla/MPRAGE, T1 SPACE, Dixon fid-uT Assessment: Flow phantom signal vs. velocity as a function of flip angle and sequence. Qualitative image assessment on 4-point scale. Quantitative evaluation of tumor-to-brain contrast, apparent contrast-to-noise ratio (aCNR), and vessel-to-brain aCNR. Statistical tests: Friedman and Mann-Whitney U tests. A P value <0.05 was considered statistically significant. Results: In the phantom, echo-uT Data conclusion: Volumetric dark blood contrast-enhanced brain MRI is feasible using echo-uT Evidence level: 3 TECHNICAL EFFICACY: Stage 1. |
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Language | English |
Publishing date | 2023-11-10 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 1146614-5 |
ISSN | 1522-2586 ; 1053-1807 |
ISSN (online) | 1522-2586 |
ISSN | 1053-1807 |
DOI | 10.1002/jmri.29124 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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