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  1. Article: Kinetics of remnant liver volume and function after a major hepatectomy.

    Truant, Stéphanie / El Amrani, Mehdi / Pruvot, François-René

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 6, Page(s) 975–977

    Language English
    Publishing date 2023-11-08
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ASO Author Reflections: Usage of Single Photon Emission CT (SPECT) Hepatobiliary Scintigraphy to Detect the Impact of Chemotherapy-Associated Liver Injuries (CALI) on Liver Function Before a Major Hepatectomy.

    Truant, Stéphanie / Pruvot, François-René

    Annals of surgical oncology

    2020  Volume 27, Issue Suppl 3, Page(s) 882–883

    MeSH term(s) Hepatectomy ; Humans ; Liver/diagnostic imaging ; Radionuclide Imaging ; Radiopharmaceuticals ; Tomography, Emission-Computed, Single-Photon
    Chemical Substances Radiopharmaceuticals
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-08996-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Response to Comment on: "Liver Venous Deprivation or Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy? A Retrospective Multicentric Study": How to Choose a Way to Enhance the Growth of Future Liver Remnant in the Future.

    Truant, Stéphanie / Chébaro, Alexandre / Pruvot, Francois-René

    Annals of surgery

    2021  Volume 276, Issue 6, Page(s) e1116–e1117

    MeSH term(s) Humans ; Hepatectomy ; Portal Vein/surgery ; Retrospective Studies ; Liver/surgery ; Liver/physiology ; Hepatic Veins ; Ligation
    Language English
    Publishing date 2021-11-16
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Comment
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000005299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sarcopenia does not affect liver regeneration and postoperative course after a major hepatectomy. A prospective study on 125 patients using CT volumetry and HIDA scintigraphy.

    Fulbert, Maxence / El Amrani, Mehdi / Baillet, Clio / Lecolle, Katia / Ernst, Olivier / Louvet, Alexandre / Pruvot, François-René / Huglo, Damien / Truant, Stéphanie

    Clinics and research in hepatology and gastroenterology

    2024  Volume 48, Issue 5, Page(s) 102332

    Abstract: Background & objectives: Sarcopenia is a morbi-mortality risk factor in digestive surgery, though its impact after major hepatectomy (MH) remains unknown. This prospective pilot study investigated whether volume and function of a regenerating liver is ... ...

    Abstract Background & objectives: Sarcopenia is a morbi-mortality risk factor in digestive surgery, though its impact after major hepatectomy (MH) remains unknown. This prospective pilot study investigated whether volume and function of a regenerating liver is influenced by body composition.
    Methods: From 2011 to 2016, 125 consecutive patients had computed tomography and 99mTc-labelled-mebrofenin SPECT-scintigraphy before and after MH at day 7 and 1 month for measurements of liver volumes and functions. L3 vertebra muscle mass identified sarcopenia. Primary endpoint was the impact of sarcopenia on regeneration capacities (i.e. volume/function changes and post-hepatectomy liver failure (PHLF) rate). Secondary endpoint was 3-month morbi-mortality.
    Results: Sarcopenic patients (SP; N = 69) were significantly older than non-sarcopenic (NSP), with lower BMI and more malignancies, but with comparable liver function/volume at baseline. Postoperatively, SP showed higher rates of ISGLS_PHLF (24.6 % vs 10.9 %; p = 0.05) but with comparable rates of severe morbidity (23.2 % vs 16.4 %; p = 0.35), overall (8.7 % vs 3.6 %; p = 0.3) and PHLF-related mortality (8,7 % vs 1.8 %; p = 0.075). After matching on the extent of resection or using propensity score, regeneration and PHLF rates were similar.
    Conclusion: This prospective study using first sequential SPECT-scintigraphy showed that sarcopenia by itself does not affect liver regeneration capacities and short-term postoperative course after MH.
    Language English
    Publishing date 2024-04-02
    Publishing country France
    Document type Journal Article
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2024.102332
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  5. Article: Transplantation (rein, foie) et grossesse.

    Pruvot, François-René

    Bulletin de l'Academie nationale de medecine

    2013  Volume 197, Issue 8, Page(s) 1609–1618

    Abstract: Fertility returns quickly after kidney or liver transplantation in women of reproductive age, and most pregnancies are associated with good fetal and maternal outcomes. These pregnancies are nonetheless at a high risk of preterm delivery, preeclampsia, ... ...

    Title translation Kidney or liver transplantation and pregnancy.
    Abstract Fertility returns quickly after kidney or liver transplantation in women of reproductive age, and most pregnancies are associated with good fetal and maternal outcomes. These pregnancies are nonetheless at a high risk of preterm delivery, preeclampsia, and low birthweight. Pregnancy has no specific impact on the graft if its function is stable prior to conception. Transplanted patients are at higher risk of death than the general population, and morbidity associated with the graft and related treatments may prevent transplanted women from caring normally for their children. Pregnancies in transplanted women must be managed by multidisciplinary teams.
    MeSH term(s) Adult ; Counseling ; Female ; Fertility ; Graft Survival ; Humans ; Infant, Newborn ; Kidney Transplantation/rehabilitation ; Liver Transplantation/rehabilitation ; Pregnancy ; Pregnancy Complications/epidemiology ; Pregnancy Complications/etiology ; Pregnancy Outcome/epidemiology ; Risk Factors
    Language French
    Publishing date 2013-11
    Publishing country Netherlands
    Document type English Abstract ; Journal Article
    ZDB-ID 213227-8
    ISSN 0001-4079
    ISSN 0001-4079
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  6. Article ; Online: Seuil d’activité minimale pour la chirurgie des cancers digestifs en France : quels sont les enjeux ?

    El Amrani, Mehdi / Turpin, Anthony / Pruvot, François-René

    Bulletin du cancer

    2019  Volume 106, Issue 6, Page(s) 512–513

    Title translation Minimum activity threshold for digestive cancer surgery in France: What are the issues?
    MeSH term(s) Cancer Care Facilities/organization & administration ; Cancer Care Facilities/statistics & numerical data ; Digestive System Neoplasms/surgery ; Digestive System Surgical Procedures/statistics & numerical data ; France ; Health Policy ; Humans ; Procedures and Techniques Utilization ; Prognosis
    Language French
    Publishing date 2019-05-15
    Publishing country France
    Document type Editorial
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2019.03.018
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  7. Article ; Online: Major hepatic resection: from volumetry to liver scintigraphy.

    Pruvot, François-René / Truant, Stéphanie

    HPB : the official journal of the International Hepato Pancreato Biliary Association

    2016  Volume 18, Issue 9, Page(s) 707–708

    MeSH term(s) Hepatectomy ; Humans ; Liver/diagnostic imaging ; Liver/surgery ; Liver Neoplasms ; Radionuclide Imaging
    Language English
    Publishing date 2016-08-30
    Publishing country England
    Document type Editorial
    ZDB-ID 2131251-5
    ISSN 1477-2574 ; 1365-182X
    ISSN (online) 1477-2574
    ISSN 1365-182X
    DOI 10.1016/j.hpb.2016.08.001
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  8. Article ; Online: Failure to rescue following proctectomy for rectal cancer: the additional benefit of laparoscopic approach in a nationwide observational study of 44,536 patients.

    El Amrani, Mehdi / Clement, Guillaume / Lenne, Xavier / Turpin, Anthony / Valibouze, Caroline / Rogosnitzky, Moshe / Theis, Didier / Pruvot, François-René / Zerbib, Philippe

    Surgical endoscopy

    2021  Volume 36, Issue 1, Page(s) 435–445

    Abstract: Background: There is growing evidence that failure to rescue (FTR) is an important factor of postoperative mortality (POM) after rectal cancer surgery and surgical approach modified post-operative outcomes. However, the impact of laparoscopy on FTR ... ...

    Abstract Background: There is growing evidence that failure to rescue (FTR) is an important factor of postoperative mortality (POM) after rectal cancer surgery and surgical approach modified post-operative outcomes. However, the impact of laparoscopy on FTR after proctectomy for rectal cancer remains unknown. The aim of this study was to compare the rates of postoperative complications and FTR after laparoscopy vs open proctectomy for cancer.
    Methods: All patients who underwent proctectomy for rectal cancer between 2012 and 2016 were included. FTR was defined as the 90-day POM rate among patients with major complications. Outcomes of patients undergoing open or laparoscopic rectal cancer surgery were compared after 1:1 propensity score matching by year of surgery, hospital volume, sex, age, Charlson score, neoadjuvant chemotherapy, tumor localization and type of anastomosis.
    Results: Overall, 44,536 patients who underwent proctectomy were included, 7043 of whom (15.8%) developed major complications. The rates of major complications, POM and FTR were significantly higher in open compared to laparoscopic procedure (major complications: 19.2% vs 13.7%, p < 0.001; POM: 5.4% vs 2.3%, p < 0.001; FTR: 13.6% vs 8.3%, p < 0.001; respectively). After matching, open and laparoscopic groups were comparable. Multivariate analysis showed that age, Charlson score, sphincter-preserving procedure and surgical approach were predictive factors for FTR. Open proctectomy was found to be a risk factor for FTR (OR 1.342, IC95% [1.066; 1.689], p = 0.012) compared to laparoscopic procedure.
    Conclusion: When complications occurred, patients operated on by open proctectomy were more likely to die.
    MeSH term(s) Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Proctectomy/adverse effects ; Proctectomy/methods ; Propensity Score ; Rectal Neoplasms ; Rectum/surgery ; Retrospective Studies
    Language English
    Publishing date 2021-04-19
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-021-08303-6
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  9. Article: Management of the right hepatic artery in pancreaticoduodenectomy: a systematic review.

    El Amrani, Mehdi / Pruvot, François-René / Truant, Stéphanie

    Journal of gastrointestinal oncology

    2016  Volume 7, Issue 2, Page(s) 298–305

    Abstract: Background: The right hepatic artery (RHA) is the most common hepatic artery (CHA) variation. This variation may be problematic in pancreaticoduodenectomy (PD). We aimed to evaluate the impact of the RHA on postoperative and oncological outcomes.: ... ...

    Abstract Background: The right hepatic artery (RHA) is the most common hepatic artery (CHA) variation. This variation may be problematic in pancreaticoduodenectomy (PD). We aimed to evaluate the impact of the RHA on postoperative and oncological outcomes.
    Methods: The PubMed database was systematically searched for comparative studies reporting management of the RHA during PD for the years 1950-2014.
    Results: A total of 2,278 patients were analyzed, of whom 440 (19%) had a RHA. The most CHA variation was a replaced RHA. The conservative approach was the most frequently adopted (87%) and only 8% of patients had a sacrifice without reconstruction of the RHA. Postoperative mortality and overall morbidity were similar between patients with and without RHA. Despite the preservation of the RHA in most cases, the rates of microscopic positive margin were also comparable between two groups with no impact of RHA on survival rates.
    Conclusions: Postoperative and oncological outcomes seemed unaffected by the RHA in PD. Prospective studies are needed to evaluate its oncological impact.
    Language English
    Publishing date 2016-03-31
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.3978/j.issn.2078-6891.2015.093
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  10. Article: Primary squamous cell carcinoma of the peristomal skin of gastrostomy in a transplant patient: a first case report.

    Lailheugue, Aurore / Gibier, Jean-Baptiste / Lassailly, Guillaume / Truant, Stéphanie / Pruvot, François-René / El Amrani, Mehdi

    Journal of gastrointestinal oncology

    2019  Volume 10, Issue 3, Page(s) 573–576

    Abstract: Gastrostomy is commonly used to provide enteral nutrition when patient require a nutrition support due to not enough oral eating. Gastrostomy tube can lead to many complications; squamous cell carcinoma (SCC) is an extremely rare complication of the site ...

    Abstract Gastrostomy is commonly used to provide enteral nutrition when patient require a nutrition support due to not enough oral eating. Gastrostomy tube can lead to many complications; squamous cell carcinoma (SCC) is an extremely rare complication of the site of gastrostomy, it was described after several years of enteral nutrition or as part of a metastasis of head and neck tumors. We describe the case of a 60-year-old man heart-liver transplanted for hereditary amyloidosis. He required the setting of a gastrostomy-tube for enteral feeding and developed after only 18 months a SCC on the site of gastrostomy confirmed in the histologic report. The increased risk of SCC in transplant patients is due to immunosuppressive therapies, even though everolimus could reduce this risk. The pose of a gastrostomy is responsible of a chronic cutaneous inflammation, which is another risk factor for SCC. In these immunocompromised patients, gastrostomy or other chronic skin injury requires special monitoring, especially if the wound does not heal.
    Language English
    Publishing date 2019-06-05
    Publishing country China
    Document type Case Reports
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.21037/jgo.2019.01.05
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