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Article: Computed Tomographic Findings of Dental Disease and Secondary Diseases of the Head Area in Client-Owned Domestic Rabbits (

Borawski, Wojciech / Kiełbowicz, Zdzisław / Kubiak-Nowak, Dominika / Prządka, Przemysław / Pasternak, Gerard

Animals : an open access journal from MDPI

2024 Volume 14, Issue 8

Abstract: Domestic rabbits have teeth that grow throughout the animal's life and are prone to disease. Clinical signs of dental disease in domestic rabbits are non-specific, and, therefore, a definitive diagnosis usually requires additional methods. This study was ...

Abstract	Domestic rabbits have teeth that grow throughout the animal's life and are prone to disease. Clinical signs of dental disease in domestic rabbits are non-specific, and, therefore, a definitive diagnosis usually requires additional methods. This study was carried out on a group of 105 domestic rabbits aged 3 to 9 years. In total, 90 domestic rabbits with dental disease visible on CT images and other secondary diseases of the head area qualified for this study. Malocclusion was found in 57 (63.3%). Retrograde elongation of the tooth apices in the mandible was present in 39 (43.3%), and it was present in the maxilla in 48 (53%). Clinical tooth crowns were overgrown in 39 (43%). Dental abscesses were present in 54 (63%). Secondary to the presence of a dental abscess, osteomyelitis was found in 43 (79% of the animals with a dental abscess). Dental inflammatory resorption was found in 36 (40%). Secondary to dental disease, nasal cavity inflammation was found in 18 (20%). Otitis media was present in six (6.7%). The most common dental disease found in this study's animals was malocclusion secondary to abnormal clinical crown abrasion and abnormal tooth growth. In domestic rabbits, osteomyelitis is a common complication of dental abscesses. Computed tomography is an invaluable diagnostic method in the diagnosis of dental disease and secondary diseases of the head area, such as inflammation of the nasal cavities or otitis media, in pet rabbits.
Language	English
Publishing date	2024-04-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani14081160
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Article ; Online: A Novel Surgical Hybrid Approach to Neoplastic Lesions in the Distal Part of the Urethra: A Pilot Series of Clinical Cases

Prządka, Przemysław / Antończyk, Agnieszka / Liszka, Bartłomiej / Borawski, Wojciech / Dzimira, Stanisław / Kiełbowicz, Zdzisław / Gąsior, Ludwika

Animals. 2023 Mar. 16, v. 13, no. 6

2023

Abstract: All the surgical approaches described to date for the removal of distal urethral tumors have some technical difficulties that make these tumors difficult to treat. The article presents for the first time the treatment results of three female dogs, ... ...

Abstract	All the surgical approaches described to date for the removal of distal urethral tumors have some technical difficulties that make these tumors difficult to treat. The article presents for the first time the treatment results of three female dogs, diagnosed with transitional cell carcinomas of the distal urethra, operated with a newly developed hybrid surgical method—a combination of laparoscopy and open surgery. This technique uses vulvovaginectomy, combined with resection of the distal urethra and prepubic urethrostomy. All of the procedures were possible to perform, without the need to carry out a laparotomy conversion. Histopathology revealed transitional cell carcinoma in all cases, with a margin of healthy tissues maintained in two out of three cases, which meant reoperation of the urethrostomy site in the remaining one case. The mean survival time was nine months. Among minor complications, recurrent cystitis was found. After the first surgery, all dogs retained full control over urination immediately after recovery from anesthesia. In one case that required reoperation, complete urinary incontinence occurred after the second procedure. The present findings suggest that hybrid surgery can be used to treat distal urethral tumors. Qualification for surgery must be limited to bitches with tumors of the distal urethra and without metastases, without the possibility of using other surgical methods, and with the owner’s full acceptance of the risk of complications.
Keywords	anesthesia ; carcinoma ; cystitis ; females ; histopathology ; hybrids ; laparoscopy ; laparotomy ; resection ; risk ; urethra ; urinary incontinence ; urination
Language	English
Dates of publication	2023-0316
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13061074
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Article: A Novel Surgical Hybrid Approach to Neoplastic Lesions in the Distal Part of the Urethra: A Pilot Series of Clinical Cases.

Prządka, Przemysław / Antończyk, Agnieszka / Liszka, Bartłomiej / Borawski, Wojciech / Dzimira, Stanisław / Kiełbowicz, Zdzisław / Gąsior, Ludwika

Animals : an open access journal from MDPI

2023 Volume 13, Issue 6

Abstract	All the surgical approaches described to date for the removal of distal urethral tumors have some technical difficulties that make these tumors difficult to treat. The article presents for the first time the treatment results of three female dogs, diagnosed with transitional cell carcinomas of the distal urethra, operated with a newly developed hybrid surgical method-a combination of laparoscopy and open surgery. This technique uses vulvovaginectomy, combined with resection of the distal urethra and prepubic urethrostomy. All of the procedures were possible to perform, without the need to carry out a laparotomy conversion. Histopathology revealed transitional cell carcinoma in all cases, with a margin of healthy tissues maintained in two out of three cases, which meant reoperation of the urethrostomy site in the remaining one case. The mean survival time was nine months. Among minor complications, recurrent cystitis was found. After the first surgery, all dogs retained full control over urination immediately after recovery from anesthesia. In one case that required reoperation, complete urinary incontinence occurred after the second procedure. The present findings suggest that hybrid surgery can be used to treat distal urethral tumors. Qualification for surgery must be limited to bitches with tumors of the distal urethra and without metastases, without the possibility of using other surgical methods, and with the owner's full acceptance of the risk of complications.
Language	English
Publishing date	2023-03-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13061074
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Article ; Online: Novel surgical approach to neoplastic lesions in the distal part of the urethra: A pilot cadaver study comparing open and hybrid techniques.

Prządka, Przemysław / Liszka, Bartłomiej / Antończyk, Agnieszka / Gąsior, Ludwika / Kiełbowicz, Zdzisław

Veterinary and comparative oncology

2022 Volume 20, Issue 1, Page(s) 336–345

Abstract: Tumours of the distal urethra in female dogs are often difficult to treat, and the surgical methods described thus far have technical limitations. This study aimed to present a novel approach to the surgical treatment of distal urethral tumours. This ... ...

Abstract	Tumours of the distal urethra in female dogs are often difficult to treat, and the surgical methods described thus far have technical limitations. This study aimed to present a novel approach to the surgical treatment of distal urethral tumours. This study used dog cadavers to evaluate the technical feasibility of surgically removing neoplastic lesions in the distal urethra and compared surgical outcomes of open surgery with those of hybrid surgery (combination of laparoscopy and open surgery). Open intact, open spayed, hybrid intact, and hybrid spayed dog cadaver groups underwent surgery (n = 6 per group). The novel surgical method was based on vulvovaginectomy (ovariohysterectomy in intact dogs), resection of the distal part of the urethra, and pre-pubic urethrostomy. Outcomes of interest included technical feasibility of each procedure, using both surgical techniques, wound length, time required to complete the procedure, and the incidence of intraoperative ureter and rectum injuries. Surgical technique and reproductive status affected operating time. Technique choice affected wound length; the surgical wound was longer in the open group than in the hybrid group. Macroscopic evaluation of the rectum did not reveal any damage to the wall. There was no evidence of ureter leakage or obstruction in any case. The present findings suggest that both open and hybrid surgery can be used to treat distal urethral tumours.
MeSH term(s)	Animals ; Cadaver ; Dog Diseases/pathology ; Dog Diseases/surgery ; Dogs ; Female ; Male ; Urethra/pathology ; Urethra/surgery ; Urethral Neoplasms/surgery ; Urethral Neoplasms/veterinary
Language	English
Publishing date	2022-01-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2129634-0
ISSN	1476-5829 ; 1476-5810
ISSN (online)	1476-5829
ISSN	1476-5810
DOI	10.1111/vco.12798
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Article: Novel surgical approach to neoplastic lesions in the distal part of the urethra: A pilot cadaver study comparing open and hybrid techniques

Prządka, Przemysław / Liszka, Bartłomiej / Antończyk, Agnieszka / Gąsior, Ludwika / Kiełbowicz, Zdzisław

Veterinary and comparative oncology. 2022 Mar., v. 20, no. 1

2022

Abstract	Tumours of the distal urethra in female dogs are often difficult to treat, and the surgical methods described thus far have technical limitations. This study aimed to present a novel approach to the surgical treatment of distal urethral tumours. This study used dog cadavers to evaluate the technical feasibility of surgically removing neoplastic lesions in the distal urethra and compared surgical outcomes of open surgery with those of hybrid surgery (combination of laparoscopy and open surgery). Open intact, open spayed, hybrid intact, and hybrid spayed dog cadaver groups underwent surgery (n = 6 per group). The novel surgical method was based on vulvovaginectomy (ovariohysterectomy in intact dogs), resection of the distal part of the urethra, and pre‐pubic urethrostomy. Outcomes of interest included technical feasibility of each procedure, using both surgical techniques, wound length, time required to complete the procedure, and the incidence of intraoperative ureter and rectum injuries. Surgical technique and reproductive status affected operating time. Technique choice affected wound length; the surgical wound was longer in the open group than in the hybrid group. Macroscopic evaluation of the rectum did not reveal any damage to the wall. There was no evidence of ureter leakage or obstruction in any case. The present findings suggest that both open and hybrid surgery can be used to treat distal urethral tumours.
Keywords	cadaver ; dogs ; females ; hybrids ; laparoscopy ; rectum ; resection ; spaying ; ureter ; urethra
Language	English
Dates of publication	2022-03
Size	p. 336-345.
Publishing place	Blackwell Publishing Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	2129634-0
ISSN	1476-5829 ; 1476-5810
ISSN (online)	1476-5829
ISSN	1476-5810
DOI	10.1111/vco.12798
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Article: Clinical usefulness of the anaesthetic protocol using low doses of tiletamine – zolazepam combination in continuous rate infusion as a partial intravenous anaesthesia in bitches undergoing laparoscopic surgery

Kucharski, Paweł / Antończyk, Agnieszka / Prządka, Przemysław / Liszka, Bartłomiej / Lachowska, Sonia / Kiełbowicz, Zdzisław

Topics in companion animal medicine. 2022,

2022

Abstract: The objective of this study was to evaluate the clinical usefulness of the combination of tiletamine-zolazepam used in low doses as a continuous rate infusion in a partial intravenous anaesthesia protocol. Fifteen clinically healthy, different breed ... ...

Abstract	The objective of this study was to evaluate the clinical usefulness of the combination of tiletamine-zolazepam used in low doses as a continuous rate infusion in a partial intravenous anaesthesia protocol. Fifteen clinically healthy, different breed bitches weighing 25.08±10.39 kg were used in this study. After a food fast for at least 12h and water fast for 4 hours, the animals were premedicated with dexmedetomidine. After 15 min, the bolus of tiletamine-zolazepam combination was given as an. Induction of general anaesthesia, immediately followed by continuous intravenous infusion. The following parameters were measured immediately after the induction of general anaesthesia and lasted until the end of the surgery: electrocardiography (ECG), heart rate (HR), systolic, diastolic, and mean arterial blood pressure (SAP, DAP, MAP), body temperature (T) respiratory rate (RR) end tidal of CO₂ (EtCO₂). During the recovery period, pain level was evaluated as well as sedation assessment. Time for successful intubation after administration of the tiletamine-zolazepam combination was within 3 minutes. Heart rate was within reference values. Systolic, diastolic, and mean arterial blood pressure were also within the reference values. Internal body temperature showed a downward trend for a whole procedure time. During recovery, only 1 patient showed symptoms of pain and signs of dissociation. In summary, the partial intravenous protocol with the use of tiletamine-zolazepam combination and low anaesthetic gases concentration is clinically useful because of ensuring the correct level of anaesthesia and stability of intraoperative parameters as well as a good recovery period.
Keywords	anesthesia ; blood pressure ; body temperature ; carbon dioxide ; dexmedetomidine ; dissociation ; electrocardiography ; heart rate ; intravenous injection ; laparoscopy ; medicine ; pain ; patients ; pets ; respiratory rate ; sedation ; tiletamine
Language	English
Publishing place	Elsevier Inc.
Document type	Article
Note	Pre-press version
ISSN	1938-9736
DOI	10.1016/j.tcam.2022.100664
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Article: Lasers in the surgical treatment of canine prostatic neoplasia and selected tumours of the male reproductive system

Tunikowska, Joanna / Prządka, Przemysław / Kiełbowicz, Zdzisław

Reproduction in domestic animals. 2020 July, v. 55 Suppl S2

2020

Abstract: Light‐based technologies are applied in various fields of medicine: for example optical diagnostics, light‐activated therapy and surgery. Although light‐based surgical procedures had hardly been a novelty, the revolutionizing moment for surgery came with ...

Abstract	Light‐based technologies are applied in various fields of medicine: for example optical diagnostics, light‐activated therapy and surgery. Although light‐based surgical procedures had hardly been a novelty, the revolutionizing moment for surgery came with the first use of light to cut tissue. Nowadays, surgical lasers are routinely used across numerous medical specialties, including gynaecology and urology. They are a part of the surgical treatment of benign prostatic hyperplasia, prostate carcinoma, penis carcinoma, genital skin lesions and orchidectomy. While in human urology lasers continue to establish their position as one of the standard surgical tools, veterinary patients are rarely treated with what here is still considered a technical innovation. However, through research on laser treatment of the prostate hyperplasia conducted on a canine model, veterinary medicine has gained a massive portion of data. It may prove beneficial for our clinical patients. In this review, we introduce the very principles of laser surgery as well as its current and future applications in oncologic surgery of the canine prostate gland and the male reproductive system.
Keywords	carcinoma ; castration ; diagnostic techniques ; dogs ; humans ; hyperplasia ; laser surgery ; medicine ; penis ; prostate gland ; prostatic neoplasms ; reproduction ; veterinary medicine
Language	English
Dates of publication	2020-07
Size	p. 32-37.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	NAL-light ; JOURNAL ARTICLE
ZDB-ID	1015187-4
ISSN	1439-0531 ; 0936-6768
ISSN (online)	1439-0531
ISSN	0936-6768
DOI	10.1111/rda.13614
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Article ; Online: Lasers in the surgical treatment of canine prostatic neoplasia and selected tumours of the male reproductive system.

Tunikowska, Joanna / Prządka, Przemysław / Kiełbowicz, Zdzisław

Reproduction in domestic animals = Zuchthygiene

2020 Volume 55 Suppl 2, Page(s) 32–37

Abstract: Light-based technologies are applied in various fields of medicine: for example optical diagnostics, light-activated therapy and surgery. Although light-based surgical procedures had hardly been a novelty, the revolutionizing moment for surgery came with ...

Abstract	Light-based technologies are applied in various fields of medicine: for example optical diagnostics, light-activated therapy and surgery. Although light-based surgical procedures had hardly been a novelty, the revolutionizing moment for surgery came with the first use of light to cut tissue. Nowadays, surgical lasers are routinely used across numerous medical specialties, including gynaecology and urology. They are a part of the surgical treatment of benign prostatic hyperplasia, prostate carcinoma, penis carcinoma, genital skin lesions and orchidectomy. While in human urology lasers continue to establish their position as one of the standard surgical tools, veterinary patients are rarely treated with what here is still considered a technical innovation. However, through research on laser treatment of the prostate hyperplasia conducted on a canine model, veterinary medicine has gained a massive portion of data. It may prove beneficial for our clinical patients. In this review, we introduce the very principles of laser surgery as well as its current and future applications in oncologic surgery of the canine prostate gland and the male reproductive system.
MeSH term(s)	Animals ; Dog Diseases/surgery ; Dogs ; Genital Neoplasms, Male/surgery ; Genital Neoplasms, Male/veterinary ; Laser Therapy/methods ; Laser Therapy/veterinary ; Male ; Prostatic Hyperplasia/surgery ; Prostatic Hyperplasia/veterinary ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/veterinary ; Urologic Surgical Procedures, Male/veterinary
Language	English
Publishing date	2020-02-03
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1015187-4
ISSN	1439-0531 ; 0936-6768
ISSN (online)	1439-0531
ISSN	0936-6768
DOI	10.1111/rda.13614
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical Usefulness of the Anaesthetic Protocol Using Low Doses of Tiletamine - Zolazepam Combination in Continuous Rate Infusion as a Partial Intravenous Anaesthesia in Bitches Undergoing Laparoscopic Surgery.

Kucharski, Paweł / Antończyk, Agnieszka / Prządka, Przemysław / Liszka, Bartłomiej / Lachowska, Sonia / Kiełbowicz, Zdzisław

Topics in companion animal medicine

2022 Volume 49, Page(s) 100664

Abstract: The objective of this study was to evaluate the clinical usefulness of the combination of tiletamine-zolazepam used in low doses as a continuous rate infusion in a partial intravenous anesthesia protocol. Fifteen clinically healthy, different breed ... ...

Abstract	The objective of this study was to evaluate the clinical usefulness of the combination of tiletamine-zolazepam used in low doses as a continuous rate infusion in a partial intravenous anesthesia protocol. Fifteen clinically healthy, different breed bitches weighing 25.08 ± 10.39 kg was used in this study. After a food fast for at least 12 hours and water fast for 4 hours, the animals were premedicated with dexmedetomidine. After 15 minutes, the bolus of tiletamine-zolazepam combination was given as an. Induction of general anesthesia, immediately followed by continuous intravenous infusion. The following parameters were measured immediately after the induction of general anesthesia and lasted until the end of the surgery: electrocardiography, heart rate, systolic arterial blood pressure, diastolic arterial blood pressure, mean arterial blood pressure, body temperature respiratory rate end tidal of CO
MeSH term(s)	Anesthesia, Intravenous/veterinary ; Anesthetics/pharmacology ; Animals ; Drug Combinations ; Heart Rate ; Laparoscopy/veterinary ; Pain/veterinary ; Tiletamine/pharmacology ; Zolazepam/pharmacology
Chemical Substances	Anesthetics ; Drug Combinations ; tiletamine, zolazepam drug combination ; Tiletamine (2YFC543249) ; Zolazepam (G1R474U58U)
Language	English
Publishing date	2022-04-08
Publishing country	United States
Document type	Journal Article
ISSN	1946-9837
ISSN (online)	1946-9837
DOI	10.1016/j.tcam.2022.100664
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Article ; Online: Altered Transcript Levels of

Wozniak, Jakub / Loba, Weronika / Wysocka, Alicja / Dzimira, Stanislaw / Przadka, Przemyslaw / Switonski, Marek / Nowacka-Woszuk, Joanna

Genes

2023 Volume 14, Issue 10

Abstract: Umbilical hernia (UH) and inguinal hernia (IH) are among the most common defects in pigs, affecting their welfare and resulting in economic losses. In this study, we aimed to verify the association of previously reported differences in transcript levels ... ...

Abstract	Umbilical hernia (UH) and inguinal hernia (IH) are among the most common defects in pigs, affecting their welfare and resulting in economic losses. In this study, we aimed to verify the association of previously reported differences in transcript levels of the
MeSH term(s)	Humans ; Swine/genetics ; Animals ; Hernia, Umbilical/genetics ; Hernia, Umbilical/veterinary ; Matrix Metalloproteinase 13/genetics ; Hernia, Inguinal ; Muscles ; Connective Tissue ; RNA, Messenger/genetics
Chemical Substances	Matrix Metalloproteinase 13 (EC 3.4.24.-) ; RNA, Messenger ; MMP13 protein, human (EC 3.4.24.-)
Language	English
Publishing date	2023-10-01
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14101903
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