Article ; Online: Associations between Urinary Concentrations of Polycyclic Aromatic Hydrocarbons and Overactive Bladder in US Adults: Data from the National Health and Nutrition Examination Survey 2005-2016.
2024 Volume 108, Issue 2, Page(s) 137–145
Abstract: Introduction: Polycyclic aromatic hydrocarbons (PAHs) are a group of chemicals that can induce oxidative stress and related cytotoxicity. Whether urinary concentrations of PAHs have effects on overactive bladder (OAB) in the general population is still ... ...
| Abstract | Introduction: Polycyclic aromatic hydrocarbons (PAHs) are a group of chemicals that can induce oxidative stress and related cytotoxicity. Whether urinary concentrations of PAHs have effects on overactive bladder (OAB) in the general population is still unclear. This study investigated the associations between urinary PAHs and OAB. Methods: 7,146 adults aged over 20 who participated in the US National Health and Nutrition Examination Survey 2005-2016 were studied. The impact of the six PAHs on OAB was evaluated by multivariate logistic regression, and percent changes related to different quartiles of those six PAH levels were calculated. Confounders including age, logarithmic urinary creatinine, gender, race, body mass index, educational level, marriage, poverty income ratio, diabetes, hypertension, and metabolic syndrome were controlled. Results: There is a significant positive correlation between urinary concentrations of the six PAHs we include in the study and the occurrence of OAB. Furthermore, individuals with higher PAH levels also reported a more severe OAB symptom score (OABSS). Conclusions: Our findings revealed that adult men in the USA with higher urinary PAHs had a higher risk of OAB incidence. These findings suggest the importance of strong environmental regulation of PAHs to protect population health. However, the underlying mechanisms still need further exploration. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Adult ; Male ; Humans ; Polycyclic Aromatic Hydrocarbons/toxicity ; Polycyclic Aromatic Hydrocarbons/urine ; Nutrition Surveys ; Urinary Bladder, Overactive ; Diabetes Mellitus ; Metabolic Syndrome ; Biomarkers | |||||
| Chemical Substances | Polycyclic Aromatic Hydrocarbons ; Biomarkers | |||||
| Language | English | |||||
| Publishing date | 2024-01-12 | |||||
| Publishing country | Switzerland | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 204045-1 | |||||
| ISSN | 1423-0399 ; 0042-1138 | |||||
| ISSN (online) | 1423-0399 | |||||
| ISSN | 0042-1138 | |||||
| DOI | 10.1159/000536253 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Ui VI Zs.180: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.