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  1. Book ; Online: Estado nutricional y habilidades metalingüísticas en la infancia

    Egoavil-Victoria, Elsa / López-Robles, Zenón / Chipana-Loayza, Pierre / Sanchez-Cordova, Gloria / Bautista-Puente, Luis / Ticse-Alfaro, Dustin

    2023  

    Keywords Education ; estado nutricional ; educación inicial ; habilidades metalingüísticas
    Language Spanish
    Size 1 electronic resource (88 pages)
    Publisher Instituto Universitario de Innovación Ciencia y Tecnología Inudi Perú
    Publishing place Puno
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030612681
    ISBN 9786125069993 ; 6125069990
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Assessment of refractive window drying of physalis (Physalis peruviana L.) puree at different temperatures: drying kinetic prediction and retention of bioactive components

    Uribe, Elsa / Gómez-Pérez, Luis S. / Pasten, Alexis / Pardo, Catalina / Puente, Luis / Vega-Galvez, Antonio

    Journal of food measurement & characterization. 2022 Aug., v. 16, no. 4

    2022  

    Abstract: The aim of this study was to assess the refractive window™ drying (RW) on retention of bioactive components and drying kinetics of physalis (Physalis peruviana) puree at different temperatures (50, 60, 70, 80 and 90 °C). Freeze-drying (FD) was used as ... ...

    Abstract The aim of this study was to assess the refractive window™ drying (RW) on retention of bioactive components and drying kinetics of physalis (Physalis peruviana) puree at different temperatures (50, 60, 70, 80 and 90 °C). Freeze-drying (FD) was used as control. Drying kinetic was evaluated by mathematical modeling. Antioxidant potential (DPPH/ORAC), total phenolic content (TPC) and total flavonoid content (TFC) were determined using spectrophotometric techniques. The content of tocopherols and fatty acid profile were determined by HPLC and GC, respectively. The Midilli & Kucuk model obtained the best fit for drying kinetics and an activation energy of 29.46 kJ/mol was determined at 60 and 70 °C. Samples showed higher antioxidant capacity with better retention of TPC (174.73 ± 7.00 mg GAE/100 g and 184.20 ± 12.60 mg GAE/100 g) and TFC (119.68 ± 4.54 mg QE/100 g and 141.60 ± 5.47 mg QE/100 g). Similar values of tocopherol contents were found between RW and FD. Linoleic acid is the main polyunsaturated constituent detected. RW showed a great retention of bioactive components, making it an alternative to preserving food.
    Keywords Physalis peruviana ; activation energy ; antioxidant activity ; fatty acid composition ; flavonoids ; freeze drying ; linoleic acid ; measurement ; prediction ; tocopherols
    Language English
    Dates of publication 2022-08
    Size p. 2605-2615.
    Publishing place Springer US
    Document type Article
    ZDB-ID 2754612-3
    ISSN 2193-4134 ; 2193-4126
    ISSN (online) 2193-4134
    ISSN 2193-4126
    DOI 10.1007/s11694-022-01373-7
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Composition and biological effects of goldenberry byproducts: an overview.

    Nocetti, Diego / Núñez, Hipólito / Puente, Luis / Espinosa, Alejandra / Romero, Fernando

    Journal of the science of food and agriculture

    2020  Volume 100, Issue 12, Page(s) 4335–4346

    Abstract: Goldenberry is a wild fruit that has been widely used for centuries, mainly in folk medicine. Most studies of goldenberry have focused on the fruit, but new research has studied its byproducts, which were considered to be waste until recently. The main ... ...

    Abstract Goldenberry is a wild fruit that has been widely used for centuries, mainly in folk medicine. Most studies of goldenberry have focused on the fruit, but new research has studied its byproducts, which were considered to be waste until recently. The main objective of our study was to systematize the published information regarding the composition of goldenberry byproducts (calyces, leaves, seeds, and pomace) and their effects on biological systems. Goldenberry byproducts contain minerals, amino acids, withanolides, flavonoids, and essential fatty acids, thus representing good sources of these compounds. Some of their major biological effects include anti-inflammatory, antioxidant, antidiabetic, and antiproliferative effects. Information regarding their toxicity is also presented here. To determine the optimal dosage, further safety studies would be recommended to ensure the best health benefits of these compounds. The available evidence has demonstrated the nutritional value of different byproducts of goldenberry, suggesting them to be potential candidates for use in the cosmetic industry, in the preparation of functional foods, and in phytomedicine for the prevention and adjuvant treatment of some diseases. © 2020 Society of Chemical Industry.
    MeSH term(s) Amino Acids/chemistry ; Antioxidants/chemistry ; Fruit/chemistry ; Functional Food/analysis ; Nutritive Value ; Physalis/chemistry ; Plant Extracts/chemistry ; Seeds/chemistry
    Chemical Substances Amino Acids ; Antioxidants ; Plant Extracts
    Language English
    Publishing date 2020-05-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.10386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exploring the Importance of Differential Expression of Autophagy Markers in Term Placentas from Late-Onset Preeclamptic Pregnancies.

    Garcia-Puente, Luis M / García-Montero, Cielo / Fraile-Martinez, Oscar / Bujan, Julia / De León-Luis, Juan A / Bravo, Coral / Rodríguez-Benitez, Patrocinio / López-González, Laura / Díaz-Pedrero, Raul / Álvarez-Mon, Melchor / García-Honduvilla, Natalio / Saez, Miguel A / Ortega, Miguel A

    International journal of molecular sciences

    2024  Volume 25, Issue 4

    Abstract: Preeclampsia (PE) is a serious hypertensive disorder affecting 4-5% of pregnancies globally, leading to maternal and perinatal morbidity and mortality and reducing life expectancy in surviving women post-gestation. Late-onset PE (LO-PE) is a clinical ... ...

    Abstract Preeclampsia (PE) is a serious hypertensive disorder affecting 4-5% of pregnancies globally, leading to maternal and perinatal morbidity and mortality and reducing life expectancy in surviving women post-gestation. Late-onset PE (LO-PE) is a clinical type of PE diagnosed after 34 weeks of gestation, being less severe than the early-onset PE (EO-PE) variant, although both entities have a notable impact on the placenta. Despite the fact that most studies have focused on EO-PE, LO-PE does not deserve less attention since its prevalence is much higher and little is known about the role of the placenta in this pathology. Via RT-qPCR and immunohistochemistry methods, we measured the gene and protein expressions of several macroautophagy markers in the chorionic villi of placentas from women who underwent LO-PE (
    MeSH term(s) Pregnancy ; Female ; Humans ; Placenta/metabolism ; Transcription Factors/metabolism ; Autophagy/genetics ; Pre-Eclampsia/metabolism ; Case-Control Studies
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25042029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Composition and biological effects of goldenberry byproducts: an overview

    Nocetti, Diego / Núñez, Hipólito / Puente, Luis / Espinosa, Alejandra / Romero, Fernando

    Journal of the science of food and agriculture. 2020 Sept., v. 100, no. 12

    2020  

    Abstract: Goldenberry is a wild fruit that has been widely used for centuries, mainly in folk medicine. Most studies of goldenberry have focused on the fruit, but new research has studied its byproducts, which were considered to be waste until recently. The main ... ...

    Abstract Goldenberry is a wild fruit that has been widely used for centuries, mainly in folk medicine. Most studies of goldenberry have focused on the fruit, but new research has studied its byproducts, which were considered to be waste until recently. The main objective of our study was to systematize the published information regarding the composition of goldenberry byproducts (calyces, leaves, seeds, and pomace) and their effects on biological systems. Goldenberry byproducts contain minerals, amino acids, withanolides, flavonoids, and essential fatty acids, thus representing good sources of these compounds. Some of their major biological effects include anti‐inflammatory, antioxidant, antidiabetic, and antiproliferative effects. Information regarding their toxicity is also presented here. To determine the optimal dosage, further safety studies would be recommended to ensure the best health benefits of these compounds. The available evidence has demonstrated the nutritional value of different byproducts of goldenberry, suggesting them to be potential candidates for use in the cosmetic industry, in the preparation of functional foods, and in phytomedicine for the prevention and adjuvant treatment of some diseases. © 2020 Society of Chemical Industry
    Keywords adjuvants ; agriculture ; antioxidants ; calyx ; flavonoids ; fruits ; industry ; nutritive value ; pomace ; toxicity ; traditional medicine
    Language English
    Dates of publication 2020-09
    Size p. 4335-4346.
    Publishing place John Wiley & Sons, Ltd.
    Document type Article
    Note NAL-AP-2-clean ; REVIEW
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.10386
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Effects of drying methods on the characterization of fatty acids, bioactive compounds and antioxidant capacity in a thin layer of physalis (

    Puente, Luis / Vega-Gálvez, Antonio / Fuentes, Ivette / Stucken, Karina / Rodríguez, Angela / Pastén, Alexis

    Journal of food science and technology

    2020  Volume 58, Issue 4, Page(s) 1470–1479

    Abstract: ... Physalis ... ...

    Abstract Physalis peruviana
    Language English
    Publishing date 2020-07-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 242498-8
    ISSN 0975-8402 ; 0022-1155
    ISSN (online) 0975-8402
    ISSN 0022-1155
    DOI 10.1007/s13197-020-04659-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comparative study of the etiology of nosocomial bacteremic pneumonia in ventilated and non-ventilated patients: a 10-year experience in an institution.

    Bouza, Emilio / Guillen-Zabala, Helmuth / Rojas, Adriana / Cañada, Gabriela / Cercenado, Emilia / Sánchez-Carrillo, Carlos / Díez, Cristina / Puente, Luis / Muñoz, Patricia / Galar, Alicia

    Microbiology spectrum

    2023  Volume 11, Issue 6, Page(s) e0151723

    Abstract: Importance: This study on bacteremic nosocomial pneumonia (bNP) demonstrates the importance of this condition both in patients undergoing and not undergoing mechanical ventilation. ...

    Abstract Importance: This study on bacteremic nosocomial pneumonia (bNP) demonstrates the importance of this condition both in patients undergoing and not undergoing mechanical ventilation.
    MeSH term(s) Humans ; Cross Infection/drug therapy ; Staphylococcus aureus ; Anti-Bacterial Agents/therapeutic use ; Healthcare-Associated Pneumonia/epidemiology ; Healthcare-Associated Pneumonia/complications ; Healthcare-Associated Pneumonia/drug therapy ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/drug therapy ; Pneumonia, Ventilator-Associated/etiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01517-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain: A Retrospective Multicenter Study.

    Dávila, Ignacio / Puente, Luis / Quirce, Santiago / Arismendi, Ebymar / Díaz-Palacios, Miguel / Pereira-Vega, Antonio / de Diego, Alfredo / Rodriguez-Hermosa, Juan Luis / Cea-Calvo, Luis / Sánchez-Jareño, Marta / López-Cotarelo, Pilar / Domingo, Christian

    Lung

    2023  Volume 201, Issue 3, Page(s) 275–286

    Abstract: Purpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are ... ...

    Abstract Purpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are challenging to diagnose and manage, with substantial economic implications for healthcare systems.
    Methods: This retrospective multicenter non-interventional study aimed to characterize the profile and health resource consumption of patients with RCC or UCC who attended outpatient clinics at Spanish hospitals. Data were collected from medical records of patients with RCC or UCC for up to 3 years before study inclusion.
    Results: The patient cohort (n = 196) was representative of the chronic cough population (77.6% female, mean age 58.5 years). Two-thirds of patients (n = 126) had RCC. The most frequently visited doctors were pulmonologists (93.4% of patients) and primary care physicians (78.6%), with a mean of 5 visits per patient over three years' observation. The most common diagnostic tests were chest x-ray (83.7%) and spirometry with bronchodilation (77.0%). The most commonly prescribed treatments were proton pump inhibitors (79.6%) and respiratory medications (87.8%). Antibiotics were prescribed empirically to 56 (28.6%) patients. Differences between RCC or UCC groups related mainly to approaches used to manage cough-associated conditions (gastroesophageal reflux disease, asthma) in patients with RCC.
    Conclusion: RCC and UCC are responsible for high health resource utilization in Spanish hospitals. Specific treatments targeting the pathological processes driving chronic cough may provide opportunities to reduce the associated burden for patients and healthcare systems.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Cough/diagnosis ; Cough/etiology ; Cough/therapy ; Spain/epidemiology ; Carcinoma, Renal Cell ; Outpatients ; Quality of Life ; Ambulatory Care Facilities ; Hospitals ; Kidney Neoplasms ; Chronic Disease
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 6165-7
    ISSN 1432-1750 ; 0341-2040
    ISSN (online) 1432-1750
    ISSN 0341-2040
    DOI 10.1007/s00408-023-00620-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Absolute concentration robustness

    Puente, Luis David García / Gross, Elizabeth / Harrington, Heather A / Johnston, Matthew / Meshkat, Nicolette / Millán, Mercedes Pérez / Shiu, Anne

    Algebra and geometry

    2023  

    Abstract: Motivated by the question of how biological systems maintain homeostasis in changing environments, Shinar and Feinberg introduced in 2010 the concept of absolute concentration robustness (ACR). A biochemical system exhibits ACR in some species if the ... ...

    Abstract Motivated by the question of how biological systems maintain homeostasis in changing environments, Shinar and Feinberg introduced in 2010 the concept of absolute concentration robustness (ACR). A biochemical system exhibits ACR in some species if the steady-state value of that species does not depend on initial conditions. Thus, a system with ACR can maintain a constant level of one species even as the environment changes. Despite a great deal of interest in ACR in recent years, the following basic question remains open: How can we determine quickly whether a given biochemical system has ACR? Although various approaches to this problem have been proposed, we show that they are incomplete. Accordingly, we present new methods for deciding ACR, which harness computational algebra. We illustrate our results on several biochemical signaling networks.

    Comment: 44 pages
    Keywords Mathematics - Algebraic Geometry ; Mathematics - Dynamical Systems ; Quantitative Biology - Molecular Networks ; 37N25 ; 92E20 ; 12D10 ; 37C25 ; 65H14 ; 14Q20
    Publishing date 2023-12-29
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Evaluation of the physical changes of different soluble fibres produced during an in vitro digestion

    Vera, Natalia / Laguna, Laura / Muñoz, Loreto A / Puente, Luis / Zura, Liliana

    Journal of functional foods. 2019 Aug. 13,

    2019  

    Abstract: Some dietary fibres, especially soluble, due to their ability to modify the physical properties of digestive content, are associated with positive physiological effects. In this study, the effect of digestion on apparent viscosity and fragmentation/ ... ...

    Abstract Some dietary fibres, especially soluble, due to their ability to modify the physical properties of digestive content, are associated with positive physiological effects. In this study, the effect of digestion on apparent viscosity and fragmentation/aggregation degree of different soluble fibres (guar gum, xanthan gum, pectin, and chia seed mucilage) were evaluated during in vitro digestion. All fibres showed pseudoplastic behaviour independent of the concentration and digestion stage, but xanthan gum and mucilage retained more viscosity compared with the other fibres. Particle size during digestion showed that pectin and guar gum had different degree of fragmentation at the intestinal level, while xanthan gum exhibited aggregation at the gastric stage and the chia mucilage remained unchanged during the digestion. The ability of xanthan gum and mucilage to conserve their structure and viscosity during digestion could help to modulate the digestive process, delay gastric emptying and enhance the functionality of foods.
    Keywords dietary fiber ; foods ; gastric emptying ; guar gum ; in vitro digestion ; intestines ; mucilages ; particle size ; pectins ; Salvia hispanica ; viscosity ; xanthan gum
    Language English
    Dates of publication 2019-0813
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2511964-3
    ISSN 1756-4646
    ISSN 1756-4646
    DOI 10.1016/j.jff.2019.103518
    Database NAL-Catalogue (AGRICOLA)

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