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  1. AU="Puga, Marcelo Lourencini"
  2. AU="Sun, Ling-Ling"
  3. AU="Onwordi, Ellis Chika"

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  1. Article ; Online: Corrigendum to "Performance of microvesicles as biomarkers of clinical outcome in sepsis and trauma: A pilot study" [Biomed. Pharmacother. 146 (2022) 112490].

    Puga, Marcelo Lourencini / Menegueti, Mayra Gonçalves / Silvestrini, Marina Malheiros Araújo / de Souza Santos, Lorena Júnia / Ferraz-Nogueira, Raquel / Basile-Filho, Anibal / Teixeira-Carvalho, Andréa / Martins-Filho, Olindo Assis / Auxiliadora-Martins, Maria

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2022  Volume 153, Page(s) 113312

    Language English
    Publishing date 2022-06-24
    Publishing country France
    Document type Published Erratum
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2022.113312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Performance of microvesicles as biomarkers of clinical outcome in sepsis and trauma: A pilot study.

    Puga, Marcelo Lourencini / Menegueti, Mayra Gonçalves / Silvestrini, Marina Malheiros Araújo / de Souza Santos, Lorena Júnia / Ferreira-Nogueira, Raquel / Basile-Filho, Anibal / Teixeira-Carvalho, Andréa / Martins-Filho, Olindo Assis / Auxiliadora-Martins, Maria

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2021  Volume 146, Page(s) 112490

    Abstract: Sepsis remains one of the main causes of death in intensive care unit (ICU) worldwide, despite all technological and scientific advances. Microvesicles (MV) have become promising biomarkers for quick and accurate monitoring of several illnesses. The aim ... ...

    Abstract Sepsis remains one of the main causes of death in intensive care unit (ICU) worldwide, despite all technological and scientific advances. Microvesicles (MV) have become promising biomarkers for quick and accurate monitoring of several illnesses. The aim of this pilot study was to characterize and evaluate the performance of MV as biomarker of clinical outcome in septic and trauma patients. For this purpose, 39 subjects, both genders, aging from 18 to 85 years were included in three groups referred as Sepsis, Trauma and Healthy Control. Kinetic analysis of MV was carried out at four consecutive time points: admission (baseline)/T1, 24 h/T2, 72 h/T3 and outcome/T4 of discharge or death. At admission, an overall increase in total MV (Annexin V
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens, CD/immunology ; Biomarkers ; Cell-Derived Microparticles ; Critical Illness ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Prognosis ; Retrospective Studies ; Sepsis/blood ; Sepsis/immunology ; Wounds and Injuries/blood ; Wounds and Injuries/immunology ; Young Adult
    Chemical Substances Antigens, CD ; Biomarkers
    Language English
    Publishing date 2021-12-07
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2021.112490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Impact of a dental care intervention on the hospital mortality of critically ill patients admitted to intensive care units: A quasi-experimental study.

    Ribeiro, Isabella Lima Arrais / Bellissimo-Rodrigues, Wanessa Teixeira / Mussolin, Mariama Gentil / Innocentini, Lara Maria Alencar Ramos / Marangoni, Adriano Tadeu Dias / Macedo, Leandro Dorigan / Barbosa-Júnior, Francisco / de Souza, Hayala Cristina Cavenague / Menegueti, Mayra Gonçalves / Pereira, Ana Paula Sulino / Gaspar, Gilberto Gambero / Schmidt, André / Miranda, Carlos Henrique / Lovato, Wilson José / Puga, Marcelo Lourencini / Auxiliadora-Martins, Maria / Basile-Filho, Anibal / Bellissimo-Rodrigues, Fernando

    American journal of infection control

    2022  Volume 50, Issue 10, Page(s) 1156–1161

    Abstract: Background: We aimed to evaluate the impact of providing dental care to critically ill patients on their risk of death and ventilator-associated pneumonia (VAP).: Methods: A quasi-experimental study was conducted in 2 intensive care units (ICU) from ... ...

    Abstract Background: We aimed to evaluate the impact of providing dental care to critically ill patients on their risk of death and ventilator-associated pneumonia (VAP).
    Methods: A quasi-experimental study was conducted in 2 intensive care units (ICU) from 2016 to 2019. The intervention consisted of implementing routine dental care, focusing on oral hygiene and periodontal treatment, at least 3 times a week, for patients admitted to the study units. In the pre-intervention period, routine oral hygiene was provided by the ICU nursing staff. The primary and secondary study outcomes were mortality, evaluated at the end of the ICU stay, and VAP incidence density, respectively. Data were analyzed using the ARIMA (autoregressive integrated moving average) time series model in R software.
    Results: During the intervention period, 5,147 dental procedures were performed among 355 patients. The time series showed that ICU mortality was 36.11%, 32.71%, and 32.30% within the 3 years before the intervention, and 28.71% during the intervention period (P = .015). VAP incidence density did not significantly change during the study period (P = .716).
    Conclusion: A dental care intervention focused on oral hygiene and periodontal treatment regularly provided by dentists to critically ill patients may decrease their risk of dying in the ICU. Randomized clinical trials should be performed to confirm these findings.
    Trial registration: WHO-affiliated Brazilian Clinical Trials Registry. RBR-4jmz36. Registered 7 October 2018, before first patient enrollment.
    MeSH term(s) Critical Illness ; Dental Care ; Hospital Mortality ; Humans ; Intensive Care Units ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/prevention & control
    Language English
    Publishing date 2022-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2022.01.022
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    In stock of ZB MED Cologne/Königswinter

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  4. Article: The Impact of Implementation of Bundle to Reduce Catheter-Related Bloodstream Infection Rates.

    Menegueti, Mayra Goncalves / Ardison, Kym Marcel Martins / Bellissimo-Rodrigues, Fernando / Gaspar, Gilberto Gambero / Martins-Filho, Olindo Assis / Puga, Marcelo Lourencini / Laus, Ana Maria / Basile-Filho, Anibal / Auxiliadora-Martins, Maria

    Journal of clinical medicine research

    2015  Volume 7, Issue 11, Page(s) 857–861

    Abstract: Background: The aim of the study was to investigate how control bundles reduce the rate of central venous catheter-associated bloodstream infections (CVC-BSIs) rates in critically ill patients.: Methods: This is a prospective before-and-after study ... ...

    Abstract Background: The aim of the study was to investigate how control bundles reduce the rate of central venous catheter-associated bloodstream infections (CVC-BSIs) rates in critically ill patients.
    Methods: This is a prospective before-and-after study designed to evaluate whether a set of control measures (bundle) can help prevent CVC-BSI. The bundles included a checklist that aimed to correct practices related to CVC insertion, manipulation, and maintenance based on guidelines of the Center for Disease Control and Prevention (CDC).
    Results: We examined 123 checklists before and 155 checklists after implementation of the training program. Compared with the pre-intervention period, CVC-BSI rates decreased. Hand hygiene techniques were used correctly. CVC-BSI incidence was 9.3 and 5.1 per 1,000 catheter-days before and after the training program, respectively.
    Conclusions: The implementation of a bundle and training program effectively reduces CVC-BSI rates.
    Language English
    Publishing date 2015-09-25
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2548987-2
    ISSN 1918-3011 ; 1918-3003
    ISSN (online) 1918-3011
    ISSN 1918-3003
    DOI 10.14740/jocmr2314w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Resuscitation fluid practices in Brazilian intensive care units: a secondary analysis of Fluid-TRIPS.

    Freitas, Flavio Geraldo Rezende de / Hammond, Naomi / Li, Yang / Azevedo, Luciano Cesar Pontes de / Cavalcanti, Alexandre Biasi / Taniguchi, Leandro / Gobatto, André / Japiassú, André Miguel / Bafi, Antonio Tonete / Mazza, Bruno Franco / Noritomi, Danilo Teixeira / Dal-Pizzol, Felipe / Bozza, Fernando / Salluh, Jorge Ibrahin Figueira / Westphal, Glauco Adrieno / Soares, Márcio / Assunção, Murillo Santucci César de / Lisboa, Thiago / Lobo, Suzana Margarete Ajeje /
    Barbosa, Achilles Rohlfs / Ventura, Adriana Fonseca / Souza, Ailson Faria de / Silva, Alexandre Francisco / Toledo, Alexandre / Reis, Aline / Cembranel, Allan / Rea Neto, Alvaro / Gut, Ana Lúcia / Justo, Ana Patricia Pierre / Santos, Ana Paula / Albuquerque, André Campos D de / Scazufka, André / Rodrigues, Antonio Babo / Fernandino, Bruno Bonaccorsi / Silva, Bruno Goncalves / Vidal, Bruno Sarno / Pinheiro, Bruno Valle / Pinto, Bruno Vilela Costa / Feijo, Carlos Augusto Ramos / Abreu Filho, Carlos de / Bosso, Carlos Eduardo da Costa Nunes / Moreira, Carlos Eduardo Nassif / Ramos, Carlos Henrique Ferreira / Tavares, Carmen / Arantes, Cidamaiá / Grion, Cintia / Mendes, Ciro Leite / Kmohan, Claudio / Piras, Claudio / Castro, Cristine Pilati Pileggi / Lins, Cyntia / Beraldo, Daniel / Fontes, Daniel / Boni, Daniela / Castiglioni, Débora / Paisani, Denise de Moraes / Pedroso, Durval Ferreira Fonseca / Mattos, Ederson Roberto / Brito Sobrinho, Edgar de / Troncoso, Edgar M V / Rodrigues Filho, Edison Moraes / Nogueira, Eduardo Enrico Ferrari / Ferreira, Eduardo Leme / Pacheco, Eduardo Souza / Jodar, Euzebio / Ferreira, Evandro L A / Araujo, Fabiana Fernandes de / Trevisol, Fabiana Schuelter / Amorim, Fábio Ferreira / Giannini, Fabio Poianas / Santos, Fabrício Primitivo Matos / Buarque, Fátima / Lima, Felipe Gallego / Costa, Fernando Antonio Alvares da / Sad, Fernando Cesar Dos Anjos / Aranha, Fernando G / Ganem, Fernando / Callil, Flavio / Costa Filho, Francisco Flávio / Dall Arto, Frederico Toledo Campo / Moreno, Geovani / Friedman, Gilberto / Moralez, Giulliana Martines / Silva, Guilherme Abdalla da / Costa, Guilherme / Cavalcanti, Guilherme Silva / Betônico, Gustavo Navarro / Reis, Hélder / Araujo, Helia Beatriz N / Hortiz Júnior, Helio Anjos / Guimaraes, Helio Penna / Urbano, Hugo / Maia, Israel / Santiago Filho, Ivan Lopes / Farhat Júnior, Jamil / Alvarez, Janu Rangel / Passos, Joel Tavares / Paranhos, Jorge Eduardo da Rocha / Marques, José Aurelio / Moreira Filho, José Gonçalves / Andrade, Jose Neto / Sobrinho, José Onofre de C / Bezerra, Jose Terceiro de Paiva / Alves, Juliana Apolônio / Ferreira, Juliana / Gomes, Jussara / Sato, Karina Midori / Gerent, Karine / Teixeira, Kathia Margarida Costa / Conde, Katia Aparecida Pessoa / Martins, Laércia Ferreira / Figueirêdo, Lanese / Rezegue, Leila / Tcherniacovsk, Leonardo / Ferraz, Leone Oliveira / Cavalcante, Liane / Rabelo, Ligia / Miilher, Lilian / Garcia, Lisiane / Tannous, Luana / Hajjar, Ludhmila Abrahão / Paciência, Luís Eduardo Miranda / Cruz Neto, Luiz Monteiro da / Bley, Macia Valeria / Sousa, Marcelo Ferreira / Puga, Marcelo Lourencini / Romano, Marcelo Luz Pereira / Nobrega, Marciano / Arbex, Marcio / Rodrigues, Márcio Leite / Guerreiro, Márcio Osório / Rocha, Marcone / Alves, Maria Angela Pangoni / Rosa, Maria Doroti / Dias, Mariza D'Agostino / Martins, Miquéias / Oliveira, Mirella de / Moretti, Miriane Melo Silveira / Matsui, Mirna / Messender, Octavio / Santarém, Orlando Luís de Andrade / Silveira, Patricio Júnior Henrique da / Vassallo, Paula Frizera / Antoniazzi, Paulo / Gottardo, Paulo César / Correia, Paulo / Ferreira, Paulo / Torres, Paulo / Silva, Pedro Gabrile M de Barros E / Foernges, Rafael / Gomes, Rafael / Moraes, Rafael / Nonato Filho, Raimundo / Borba, Renato Luis / Gomes, Renato V / Cordioli, Ricardo / Lima, Ricardo / López, Ricardo Pérez / Gargioni, Ricardo Rath de Oliveira / Rosenblat, Richard / Souza, Roberta Machado de / Almeida, Roberto / Narciso, Roberto Camargo / Marco, Roberto / Waltrick, Roberto / Biondi, Rodrigo / Figueiredo, Rodrigo / Dutra, Rodrigo Santana / Batista, Roseane / Felipe, Rouge / Franco, Rubens Sergio da Silva / Houly, Sandra / Faria, Sara Socorro / Pinto, Sergio Felix / Luzzi, Sergio / Sant'ana, Sergio / Fernandes, Sergio Sonego / Yamada, Sérgio / Zajac, Sérgio / Vaz, Sidiner Mesquita / Bezerra, Silvia Aparecida Bezerra / Farhat, Tatiana Bueno Tardivo / Santos, Thiago Martins / Smith, Tiago / Silva, Ulysses V A / Damasceno, Valnei Bento / Nobre, Vandack / Dantas, Vicente Cés de Souza / Irineu, Vivian Menezes / Bogado, Viviane / Nedel, Wagner / Campos Filho, Walther / Dantas, Weidson / Viana, William / Oliveira Filho, Wilson de / Delgadinho, Wilson Martins / Finfer, Simon / Machado, Flavia Ribeiro

    Revista Brasileira de terapia intensiva

    2021  Volume 33, Issue 2, Page(s) 206–218

    Abstract: Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS.: Methods: This was a prospective, international, cross-sectional, observational ...

    Title translation Práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras: uma análise secundária do estudo Fluid-TRIPS.
    Abstract Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS.
    Methods: This was a prospective, international, cross-sectional, observational study in a convenience sample of intensive care units in 27 countries (including Brazil) using the Fluid-TRIPS database compiled in 2014. We described the patterns of fluid resuscitation use in Brazil compared with those in other countries and identified the factors associated with fluid choice.
    Results: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Brazil: 71.7% versus other countries: 56.4%, p < 0.001). In Brazil, the percentage of patients receiving crystalloid solutions was higher (97.7% versus 76.8%, p < 0.001), and 0.9% sodium chloride was the most commonly used crystalloid (62.5% versus 27.1%, p < 0.001). The multivariable analysis suggested that the albumin levels were associated with the use of both crystalloids and colloids, whereas the type of fluid prescriber was associated with crystalloid use only.
    Conclusion: Our results suggest that crystalloids are more frequently used than colloids for fluid resuscitation in Brazil, and this discrepancy in frequencies is higher than that in other countries. Sodium chloride (0.9%) was the crystalloid most commonly prescribed. Serum albumin levels and the type of fluid prescriber were the factors associated with the choice of crystalloids or colloids for fluid resuscitation.
    MeSH term(s) Brazil ; Critical Illness ; Cross-Sectional Studies ; Fluid Therapy ; Humans ; Intensive Care Units ; Isotonic Solutions ; Prospective Studies ; Rehydration Solutions ; Resuscitation
    Chemical Substances Isotonic Solutions ; Rehydration Solutions
    Language English
    Publishing date 2021-07-05
    Publishing country Brazil
    Document type Journal Article ; Observational Study
    ZDB-ID 2732162-9
    ISSN 1982-4335 ; 1982-4335
    ISSN (online) 1982-4335
    ISSN 1982-4335
    DOI 10.5935/0103-507X.20210028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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