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  1. Article ; Online: Electronic cigarette use among Italian smokers: patterns, settings, and adverse events.

    Gallus, Silvano / Borroni, Elisa / Liu, Xiaoqiu / Carrozzi, Laura / Dalla Pietra, Gianfranco / Eslami Varzaneh, Shokoofe / Harari, Sergio / Inciso, Giovanni / Martucci, Paola / Papale, Maria / Pistelli, Francesco / Polla, Biagio / Polo, Maria Francesca / Principe, Rosastella / Pulerà, Nolita / Raschi, Stefania / Sarzani, Riccardo / Serafini, Antonella / Odone, Anna /
    van den Brandt, Piet / Lugo, Alessandra

    Tumori

    2020  , Page(s) 300891620915784

    Abstract: Objective: Information is scanty on the patterns and settings of electronic cigarette use and on its possible adverse events. To fill the knowledge gap on these issues, we conducted a survey among ever-smokers attending smoking cessation services (SCS) ... ...

    Abstract Objective: Information is scanty on the patterns and settings of electronic cigarette use and on its possible adverse events. To fill the knowledge gap on these issues, we conducted a survey among ever-smokers attending smoking cessation services (SCS) in Italy.
    Methods: In 2016-2018, we enrolled 395 ever-smokers aged ⩾18 years who were current or former electronic cigarette users in 12 SCS from northern, central, and southern Italy.
    Results: In all, 12.4% of ever smokers were regular, 9.4% occasional, and 78.2% past users of electronic cigarettes. Of all users, 93.8% consumed electronic cigarettes with nicotine, 95.9% used refillable devices, and 76.6% purchased electronic cigarette devices or liquids in vape shops. The mean duration of use was 3.7 months and the mean number of puffs per day was 86. Among users, 71.5% used electronic cigarettes in at least 1 smoke-free indoor environment, 53.7% in workplaces, 49.5% in restaurants and bars, 33.5% in train/metro stations or airports, and 18.4% in public transports. The use of electronic cigarettes in smoke-free environments significantly decreased with age and increased with duration of use and nicotine dependence. In our sample, 47.1% reported at least 1 adverse event attributable to electronic cigarette use: 19.5% dry cough, 12.0% dry mouth, 7.6% throat or mouth irritation, and 6.8% sore throat.
    Conclusion: In Italy, most conventional cigarette smokers use electronic cigarettes where smoking conventional cigarettes is prohibited. About half of users reported 1 or more symptoms attributable to electronic cigarettes, despite the relatively short duration of use.
    Language English
    Publishing date 2020-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.1177/0300891620915784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mild/Moderate Asthma Network in Italy (MANI): a long-term observational study.

    Braido, Fulvio / Blasi, Francesco / Canonica, Giorgio Walter / Paggiaro, Pierluigi / Beghè, Bianca / Bonini, Matteo / Carpagnano, Giovanna Elisiana / Del Giacco, Stefano / Lavorini, Federico / Milanese, Manlio / Patella, Vincenzo / Santus, Pierachille / Contoli, Marco / Allegrini, Chiara / Baiardini, Ilaria / Bonzano, Laura / Caiaffa, Maria Filomena / Castelnuovo, Paolo / Corsico, Angelo Guido /
    Cosmi, Lorenzo / Costantino, Maria Teresa / Cottini, Marcello / Crimi, Nunzio / Crivellaro, Maria Angiola / D'Alò, Simona / Folletti, Ilenia / Fornari, Dario / Foschino-Barbaro, Maria Pia / Franceschini, Laura / Gargano, Domenico / Oliani, Kim Lokar / Maniscalco, Mauro / Melissari, Laura / Montagni, Marcello / Montuschi, Paolo / Murgia, Nicola / Pannofino, Alessandro / Papi, Alberto / Parente, Roberta / Pelaia, Girolamo / Pini, Laura / Puggioni, Francesca / Pulerà, Nolita / Resta, Onofrio / Ricciardi, Luisa / Ridolo, Erminia / Savi, Eleonora / Savoia, Francesca / Scala, Guglielmo / Senna, Gianenrico / Tripodi, Salvatore / Vatrella, Alessandro / Ventura, Maria Teresa / Viviano, Vittorio Maria / Yacoub, Mona-Rita

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2021  Volume 59, Issue 9, Page(s) 1908–1913

    Abstract: Objective: The prevalence of asthma in Italy is estimated to be around 4%; it affects approximately 2,000,000 citizens, and up to 80-90% of patients have mild-to-moderate asthma. Despite the clinical relevance of mild-to-moderate asthma, longitudinal ... ...

    Abstract Objective: The prevalence of asthma in Italy is estimated to be around 4%; it affects approximately 2,000,000 citizens, and up to 80-90% of patients have mild-to-moderate asthma. Despite the clinical relevance of mild-to-moderate asthma, longitudinal observational data are very limited, including data on disease progression (worsening vs. improvement), the response to treatment, and prognosis. Studies are needed to develop long-term, observational, real-life research in large cohorts. The primary outcomes of this study will be based on prospective observation and the epidemiological evolution of mild and moderate asthma. Secondary outcomes will include patient-reported outcomes, treatments over time, disease-related functional and inflammatory patterns, and environmental and life-style influences.
    Methods: This study, called the Mild/Moderate Asthma Network of Italy (MANI), is a research initiative launched by the Italian Respiratory Society and the Italian Society of Allergology, Asthma and Clinical Immunology. MANI is a cluster-based, real world, cross-sectional, prospective, observational cohort study that includes 20,000 patients with mild-to-moderate asthma. (ClinicalTrials.gov Identifier: NCT04796844).
    Results and conclusion: Despite advances in asthma care, several research gaps remain to be addressed through clinical research. This study will add important new knowledge about long-term disease history, the transferability of clinical research results to daily practice, the efficacy of currently recommended strategies, and their impact on the burden and evolution of the disease.
    Abbreviations: MANI:Mild/Moderate Asthma Network of ItalySANI:Severe Asthma Network ItalyGINA:Global Initiative for AsthmaSABA:short acting β2-agonistsICS:inhaled corticosteroidsCRF:Case Report Form.
    MeSH term(s) Administration, Inhalation ; Anti-Asthmatic Agents/therapeutic use ; Asthma/drug therapy ; Asthma/epidemiology ; Cross-Sectional Studies ; Disease Progression ; Humans ; Prospective Studies ; Quality of Life
    Chemical Substances Anti-Asthmatic Agents
    Language English
    Publishing date 2021-09-01
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2021.1968895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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