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  1. Article ; Online: Challenges in the treatment and prevention of monkeypox infection; A comprehensive review.

    Nyame, Jennifer / Punniyakotti, Saranya / Khera, Kanav / Pal, Rashmi Saxena / Varadarajan, Nithya / Sharma, Prachi

    Acta tropica

    2023  Volume 245, Page(s) 106960

    Abstract: Human monkeypox (HMPX) is a zoonotic disease, literally meaning that it can be passed on from animals (non-primate) to human (primate). All the reported and recorded cases have been traced back either to international travel or import of African animals. ...

    Abstract Human monkeypox (HMPX) is a zoonotic disease, literally meaning that it can be passed on from animals (non-primate) to human (primate). All the reported and recorded cases have been traced back either to international travel or import of African animals. In the Unites states, sporadic monkeypox cases have been reported in specific over the past 50 years, starting its first identification in the Democratic Republic of the Congo (D.R.C.) in 1970. Due to its extreme versatility, this disease poses threat as a serious public health issue that needs to be monitored, researched and prevented. Data indicate that prior immunization with the smallpox vaccine is beneficial and may provide protection against the monkeypox virus. JYNNEOSTM is a live viral vaccine that has been approved to improve clinical manifestations of the infection. On the other hand, public ignorance about safety precaution towards monkeypox post-COVID is another challenge that needs to be overcome in tackling HMPX as a possible re-emergent infection. This review is a collation of the epidemiology, etiology, transmission, clinical features and treatment of human monkeypox (HMPX).
    MeSH term(s) Animals ; Humans ; Mpox (monkeypox)/epidemiology ; Mpox (monkeypox)/prevention & control ; COVID-19 ; Monkeypox virus ; Smallpox Vaccine ; Zoonoses/epidemiology ; Zoonoses/prevention & control
    Chemical Substances Smallpox Vaccine
    Language English
    Publishing date 2023-06-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210415-5
    ISSN 1873-6254 ; 0001-706X
    ISSN (online) 1873-6254
    ISSN 0001-706X
    DOI 10.1016/j.actatropica.2023.106960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A retrospective study on evaluation of anti-hypertensive drugs used in gestational hypertension.

    Prabahar, Kousalya / Katikam, Teja / Punniyakotti, Saranya / Devanandan, Praveen

    Pakistan journal of pharmaceutical sciences

    2019  Volume 32, Issue 1, Page(s) 213–215

    Abstract: To evaluate the anti-hypertensive drugs used in pregnancy induced hypertension and to determine the safety of the anti-hypertensive drugs administered in gestational hypertensive patients. Pregnancy induced hypertension are very common in women and if ... ...

    Abstract To evaluate the anti-hypertensive drugs used in pregnancy induced hypertension and to determine the safety of the anti-hypertensive drugs administered in gestational hypertensive patients. Pregnancy induced hypertension are very common in women and if unnoticed may lead to severe complications. The appropriate therapy is very much essential for the welfare of both the mother and the child. Hence this study was undertaken to identify the commonly used and safe drugs in pregnancy induced hypertension. This retrospective study was carried out in the Medical Records Department of a specialized gynecological hospital. Patient details - Name, Age, Sex, Occupation, Body Mass Index (BMI), Social History (SH), Past Medical History (PMH), Diagnosis, mother weight and BP, baby weight, specific anti-hypertensives given, outcome, complication in both mother and baby if any, duration of anti-hypertensive drug use, duration of hospital stay were all recorded in a proforma. Adverse Drug Reactions for anti-hypertensive drugs given were also noted. Nifedipine was the most common drug prescribed both in monotherapy and dual therapy. Adverse drug reaction was seen only in 2% of patients. Pregnancy induced hypertension is one of the riskiest conditions to occur during pregnancy. Dietary modification and lifestyle modification might help in controlling pre-eclampsia.
    MeSH term(s) Adult ; Antihypertensive Agents/adverse effects ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Drug-Related Side Effects and Adverse Reactions/etiology ; Female ; Humans ; Hypertension, Pregnancy-Induced/diagnosis ; Hypertension, Pregnancy-Induced/drug therapy ; Hypertension, Pregnancy-Induced/physiopathology ; Patient Safety ; Pregnancy ; Pregnancy Outcome ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Treatment Outcome ; Young Adult
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2019-02-01
    Publishing country Pakistan
    Document type Journal Article ; Observational Study
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Drug utilization evaluation of third generation cephalosporins using core drug use indicators.

    Kaliamoorthy, Kousalya / Sankaralingam, Ramalakshmi / Punniyakotti, Saranya / Janardhan, Vasantha / Cheekala, Umamaheswara Reddy

    Pakistan journal of pharmaceutical sciences

    2012  Volume 25, Issue 2, Page(s) 339–342

    Abstract: To evaluate the drug utilization of third generation cephalosporins using core drug use indicators in various wards of Sri Ramachandra Hospital. Third generation cephalosporins are the most commonly prescribed broad spectrum antibiotic even before the ... ...

    Abstract To evaluate the drug utilization of third generation cephalosporins using core drug use indicators in various wards of Sri Ramachandra Hospital. Third generation cephalosporins are the most commonly prescribed broad spectrum antibiotic even before the culture sensitivity results arrives. Hence this study was undertaken to study the drug utilization evaluation of third generation cephalosporins in the inpatient department of various wards of Sri Ramachandra Hospital. A prospective study was conducted between July 2009 and February 2010. Prescriptions of 364 patients containing third generation cephalosporins admitted in inpatient department of various wards of Sri Ramachandra Hospital, Chennai were collected and using WHO basic drug indicators, the utilization pattern were analyzed. The average number of drugs per prescription was found to be 7.89 on prescription analysis. Cefixime was the most frequently prescribed (32.69%) oral third generation cephalosporins, followed by cefotaxime (31.32%). Among IV third generation cephalosporins, cefotaxime was the most frequently prescribed injections (35.4%). Only 28.02% of drugs were prescribed by generic name. The results obtained represent the over all prescribing pattern of third generation cephalosporins in the Tertiary Care Teaching Hospital, Chennai.
    MeSH term(s) Adolescent ; Adult ; Aged ; Cephalosporins/therapeutic use ; Child ; Child, Preschool ; Drug Utilization Review ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged
    Chemical Substances Cephalosporins
    Language English
    Publishing date 2012-04
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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