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  1. Article: A Multimodal Exertional Test for concussion: a pilot study in healthy athletes.

    Pyndiura, Kyla L / Di Battista, Alex P / Richards, Doug / Reed, Nick / Lawrence, David W / Hutchison, Michael G

    Frontiers in neurology

    2024  Volume 15, Page(s) 1390016

    Abstract: Introduction: Exertional tests have become a promising tool to assist clinicians in the management of concussions, however require expensive equipment, extensive spaces, and specialized clinician expertise. As such, we developed a test with minimal ... ...

    Abstract Introduction: Exertional tests have become a promising tool to assist clinicians in the management of concussions, however require expensive equipment, extensive spaces, and specialized clinician expertise. As such, we developed a test with minimal resource requirements encompassing key elements of sport and physical activity. The purpose of this study was to pilot test the Multimodal Exertional Test (MET) protocol in a sample of healthy interuniversity athletes.
    Methods: The MET comprises four stages, each featuring three distinct tasks. The test begins with engaging in squats, alternating reverse lunges, and hip hinges (
    Results: Fourteen healthy interuniversity athletes (
    Conclusion: Among healthy athletes, the MET elicits an increase in average and maximum HR throughout the protocol without symptom provocation. Female athletes exhibit higher HRs during all four stages in comparison to male athletes.
    Language English
    Publishing date 2024-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1390016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A history of concussion is associated with minimal perturbations to heart rate variability in athletes.

    Pyndiura, Kyla L / Di Battista, Alex P / Hutchison, Michael G

    Brain injury

    2020  Volume 34, Issue 10, Page(s) 1416–1421

    Abstract: Purpose: To compare heart rate variability (HRV) in healthy male and female athletes with versus without a history of concussion.: Methods: A cross-sectional study of 113 healthy interuniversity athletes (n = 62 female; n = 51 male) across nine ... ...

    Abstract Purpose: To compare heart rate variability (HRV) in healthy male and female athletes with versus without a history of concussion.
    Methods: A cross-sectional study of 113 healthy interuniversity athletes (n = 62 female; n = 51 male) across nine sports from a single institution, participating within the first half of their respective athletic seasons. Concussion history was determined by self-report (males: yes = 20, no = 31; females: yes = 21, no = 41). HRV was measured over five-minute time intervals in both seated and supine positions. All analyses were adjusted for age.
    Results: No differences in HRV were observed in female athletes with versus without a history of concussion; male athletes with a history of concussion displayed a significantly lower mean RR in the seated position compared to athletes with no history of concussion.
    Conclusion: In the months-to-years following a concussion, HRV does not appear to be significantly perturbed. However, males with a history of concussion may have a slightly lower mean RR. Future studies evaluating HRV and concussion history should be mindful of the confounding influence of sex and age.
    MeSH term(s) Athletes ; Athletic Injuries/complications ; Brain Concussion/complications ; Cross-Sectional Studies ; Female ; Heart Rate ; Humans ; Male
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639115-1
    ISSN 1362-301X ; 0269-9052
    ISSN (online) 1362-301X
    ISSN 0269-9052
    DOI 10.1080/02699052.2020.1802661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Randomized controlled trial of early aerobic exercise following sport-related concussion: Progressive percentage of age-predicted maximal heart rate versus usual care.

    Hutchison, Michael G / Di Battista, Alex P / Lawrence, David W / Pyndiura, Kyla / Corallo, Danielle / Richards, Doug

    PloS one

    2022  Volume 17, Issue 12, Page(s) e0276336

    Abstract: Objective: To examine the effect of a readily accessible, structured aerobic exercise intervention on days to asymptomatic status and days to medical clearance compared to usual care exercise prescription in a cohort of adolescents and young adults ... ...

    Abstract Objective: To examine the effect of a readily accessible, structured aerobic exercise intervention on days to asymptomatic status and days to medical clearance compared to usual care exercise prescription in a cohort of adolescents and young adults following sport-related concussion (SRC).
    Methods: A longitudinal, randomized, non-blinded clinical trial consisting of a structured aerobic exercise protocol (SAEP) group and a usual care exercise prescription (UCEP) group. Participants in the SAEP group underwent an exercise protocol including 8 sessions over 11 days progressing in duration and intensity stepwise based on participants' age-predicted maximal heart rate. Symptom follow-ups were on days 7, 14, 21, and 28. The primary outcome measures of the study were days to asymptomatic status and days to medical clearance, while the secondary outcome measure was symptom severity on days 7, 14, 21, and 28.
    Results: 38 participants (SAEP, n = 20; UCEP, n = 19) were recruited and completed all follow-up appointments. Compared to the UCEP group, the SAEP had a faster time to asymptomatic status with 96% posterior probability. In addition, the SAEP group displayed an earlier time to medical clearance with 93% posterior probability. While symptom severity scores did not differ between groups at enrolment (SAEP symptom severity, 30; UCEP, 29), they were subsequently lower in the SAEP group at all assessments throughout the trial with 100% posterior probability.
    Conclusions: An aerobic exercise protocol based on percentages of age-predicted maximum heart rate is a safe and effective treatment for reducing symptoms and can be initiated during the first week following SRC.
    Trial registration: ClinicalTrials.gov, no. NCT02969824.
    Language English
    Publishing date 2022-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0276336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incidence of Remote Near-Point of Convergence in University Athletes After Sport-Related Concussion.

    Hutchison, Michael G / Di Battista, Alex P / Pyndiura, Kyla / Blanc, Shirley / Quaid, Patrick T / Richards, Doug

    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

    2022  Volume 33, Issue 3, Page(s) 258–263

    Abstract: Objective: Near-point of convergence (NPC) testing is an attractive screening tool in the sport setting because it is rapid, requires few resources, and is easy to administer. Remote NPC has been reported after sport-related concussion (SRC), although ... ...

    Abstract Objective: Near-point of convergence (NPC) testing is an attractive screening tool in the sport setting because it is rapid, requires few resources, and is easy to administer. Remote NPC has been reported after sport-related concussion (SRC), although the incidence among a university-aged population is not well defined. The purpose of the study was to examine the incidence of remote NPC after SRC in a cohort of Canadian interuniversity athletes.
    Design: Cross-sequential.
    Setting: University.
    Participants: One hundred thirty-two university athletes [SRC, n = 68; musculoskeletal (MSK) injury, n = 64] were tested before the beginning of their competitive season and again after their injury.
    Independent variables: Healthy athletes measured preseason were compared with athletes after SRC or MSK injury using both longitudinal and cross-sectional designs.
    Main outcome measures: Remote NPC (pass/fail), measured at 6 cm or greater, repeated 3 times.
    Results: After SRC, 22% of athletes failed their test postinjury (95% CI, 14%-33%). Comparatively, in the MSK group, 3% of athletes failed their test postinjury (95% CI, 1%-7%). A direct comparison of both injury groups yielded a mean 19% higher prevalence of failed NPC tests after SRC versus MSK injury (95% CI, 10%-30%). There seems to be no relationship between reported symptom burden and NPC performance after SRC.
    Conclusion: Remote NPC occurs in approximately 1 of 5 athletes after SRC and is rarely observed after MSK injury.
    MeSH term(s) Humans ; Aged ; Athletic Injuries/epidemiology ; Athletic Injuries/diagnosis ; Incidence ; Universities ; Cross-Sectional Studies ; Canada ; Brain Concussion/epidemiology ; Brain Concussion/diagnosis ; Athletes
    Language English
    Publishing date 2022-12-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062530-6
    ISSN 1536-3724 ; 1050-642X
    ISSN (online) 1536-3724
    ISSN 1050-642X
    DOI 10.1097/JSM.0000000000001102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ten-Word List Performance in Healthy Athletes and Athletes at 3-to-5 Days Following Concussion.

    Hutchison, Michael G / Di Battista, Alex P / Pyndiura, Kyla L / Corallo, Danielle N / Lawrence, David W / Richards, Doug

    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

    2021  Volume 32, Issue 4, Page(s) e354–e360

    Abstract: Objective: Although the word recall component of the Sport Concussion Assessment Tool (SCAT) was updated from 5-to-10 words, its clinical utility across athletic populations remains unknown. The purpose of this study was to provide normative data on the ...

    Abstract Objective: Although the word recall component of the Sport Concussion Assessment Tool (SCAT) was updated from 5-to-10 words, its clinical utility across athletic populations remains unknown. The purpose of this study was to provide normative data on the SCAT-5 10-word test and examine its discriminative ability between healthy university level athletes and those with sport-related concussion (SRC).
    Design: Cross-sectional.
    Setting: University.
    Participants: Three hundred sixty-three (363, M = 220, F = 153) healthy athletes and 49 (M = 30, F = 19) athletes following SRC.
    Independent variable: Healthy athletes measured preseason were compared with athletes following an SRC (median = 4.0 days postinjury).
    Main outcome measure: Ten-word list performance from the SCAT-5.
    Results: There were no significant differences in either immediate ( P = 0.228, Cohen's D = 0.18) or delayed ( P = 0.908, Cohen's D = 0.02) recall tests between athletes with SRC and healthy athletes; the null findings extended to both the male and female subset comparisons. Among healthy athletes, females outperformed males on both immediate (mean difference = 1.0, P < 0.001) and delayed (mean difference = 0.5, P = 0.006) recall tasks.
    Conclusion: Concussion does not seem to impact immediate or delayed recall of the 10-word list in the subacute period following injury. Practitioners should be mindful of sex differences and the time point of administration following injury.
    MeSH term(s) Athletes ; Athletic Injuries/diagnosis ; Brain Concussion/diagnosis ; Cross-Sectional Studies ; Female ; Humans ; Male ; Neuropsychological Tests ; Universities
    Language English
    Publishing date 2021-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062530-6
    ISSN 1536-3724 ; 1050-642X
    ISSN (online) 1536-3724
    ISSN 1050-642X
    DOI 10.1097/JSM.0000000000000941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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