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  1. Article: Efficacy and safety profile of Glucagon-Like Peptide-1 Receptor Agonist in obese Type-2 diabetes patients from a private institution in Karachi.

    Qasim, Saeeda Fouzia / Ahsan, Tasnim / Ghaus, Saima / Imran, Paras

    Pakistan journal of medical sciences

    2023  Volume 39, Issue 4, Page(s) 1113–1118

    Abstract: Objective: To assess the effectiveness of GLP-1RAs in managing obese T2DM patients.: Methods: This prospective cohort analysis was conducted at Medicell Institute of Diabetes, Karachi, Pakistan; from July 2019 to July 2021. A total of 97 obese ... ...

    Abstract Objective: To assess the effectiveness of GLP-1RAs in managing obese T2DM patients.
    Methods: This prospective cohort analysis was conducted at Medicell Institute of Diabetes, Karachi, Pakistan; from July 2019 to July 2021. A total of 97 obese individuals >16 years of age with T2DM and IGT were initially enrolled, and 81 patients who showed up for the follow-up were prescribed one of the three GLP-1RAs available in Pakistan.
    Results: Out of 81 patients who showed up for the follow-up visit, 43 had received Liraglutide, 25 were taking Dulaglutide, and 13 had been prescribed IDegLira supplemented with oral hypoglycemic medications ± insulin. The mean age of the enrolled patients was 49.21(12.44) years, and there was female predominance (55.6%). Overall, there was a significant weight and BMI reduction among the patients treated with either of the GLP-1RAs (
    Conclusion: GLP-1RAs showed favorable weight and HbA1c reduction among patients of all three treatment groups.
    Language English
    Publishing date 2023-08-08
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.39.4.7353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Frequency of Metabolic Syndrome in Chronic Hepatitis C Patients: Findings From a Lower Middle Income Country.

    Qasim, Saeeda Fouzia / Jami, Ajmaal / Imran, Paras / Mushtaque, Romana / Khan, Rashid Naseem

    Cureus

    2020  Volume 12, Issue 12, Page(s) e11975

    Abstract: Introduction The world over, hepatitis C virus (HCV) engenders the risk of developing chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC). It has many extrahepatic manifestations, among which diabetes and metabolic syndrome (MetS) has been ... ...

    Abstract Introduction The world over, hepatitis C virus (HCV) engenders the risk of developing chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC). It has many extrahepatic manifestations, among which diabetes and metabolic syndrome (MetS) has been increasingly recognized and has become an active research field. The current study aimed to ascertain the frequency of MetS in chronic hepatitis C patients and to curb its long-term adverse outcomes. Methods  In our cross-sectional analysis, a total of 331 subjects diagnosed with chronic HCV were registered from June 2017 to November 2018 in two tertiary care hospitals of Karachi, Pakistan. Metabolic syndrome (MetS) was delineated following the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III). Categorical variables were compared by using the Chi-square test, and a significant P value was at the value of < 0.05. Results We found that adults of 40 - 49 years of age were the worst sufferers of hepatitis C. Out of the total 331 patients of hepatitis C, 97 (29.3%) cases were suffering from metabolic syndrome.  Conclusion Prevalence of MetS is substantial among HCV-infected individuals Therefore estimation of MetS in individuals with HCV infection is imperative and patients should be educated for lifestyle modification, diet, and weight control. However, we cannot generalized the results of our study as it was done in some tertiary care centres, so additional surveys are warranted to know the actual prevalence of MetS in our entire population.
    Language English
    Publishing date 2020-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.11975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lead toxicity in battery workers.

    Qasim, Saeeda Fouzia / Baloch, Malka

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2014  Volume 24 Suppl 3, Page(s) S284–6

    Abstract: Lead poisoning is a medical condition caused by increased levels of lead in the body. Routes of exposure include contaminated air, water, soil, food and consumer products. Occupational exposure is the main cause of lead poisoning in the adults. Two cases ...

    Abstract Lead poisoning is a medical condition caused by increased levels of lead in the body. Routes of exposure include contaminated air, water, soil, food and consumer products. Occupational exposure is the main cause of lead poisoning in the adults. Two cases of occupational lead poisoning in adult battery workers are hereby presented. Both male patients had initial non-specific symptoms of intermittent abdominal pain, fatigue and headache for 6 - 8 years. Later on, they developed psychosis, slurred speech, tremors of hands and initially underwent treatment for Parkinsonism and Wilson's disease because of clinical misdiagnosis. They were diagnosed with lead poisoning later and were treated successfully with lead chelator (CaNa2 EDTA).
    MeSH term(s) Abdominal Pain/chemically induced ; Abdominal Pain/etiology ; Adult ; Anemia/chemically induced ; Humans ; Lead/blood ; Lead Poisoning/blood ; Lead Poisoning/complications ; Lead Poisoning/diagnosis ; Male ; Occupational Diseases/blood ; Occupational Diseases/complications ; Occupational Diseases/diagnosis ; Occupational Exposure/adverse effects
    Chemical Substances Lead (2P299V784P)
    Language English
    Publishing date 2014-11
    Publishing country Pakistan
    Document type Case Reports ; Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 11.2014/JCPSP.S284S286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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