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  1. Article: [How I manage B cell lymphoma patients treated with CD19 specific CAR-T cell throughout whole-process management].

    Qian, W B / Liu, H

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2022  Volume 43, Issue 3, Page(s) 197–202

    MeSH term(s) Antigens, CD19 ; Humans ; Immunotherapy, Adoptive/adverse effects ; Lymphoma, B-Cell/etiology ; Lymphoma, B-Cell/therapy ; Receptors, Antigen, T-Cell ; T-Lymphocytes
    Chemical Substances Antigens, CD19 ; Receptors, Antigen, T-Cell
    Language Chinese
    Publishing date 2022-04-11
    Publishing country China
    Document type Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2022.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Characteristics and impact factors of SARS-CoV-2 infection in adult patients with relapsed/refractory B-cell non-Hodgkin lymphoma receiving chimeric antigen receptor T-cell therapy].

    Ge, T / Liu, H / Wang, Z H / Cao, Y / Zhang, Y C / Huang, L / Qian, W B / Zhou, X X

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2023  Volume 44, Issue 10, Page(s) 825–831

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Adult ; Middle Aged ; Receptors, Chimeric Antigen ; Retrospective Studies ; COVID-19/therapy ; SARS-CoV-2 ; Lymphoma, B-Cell/therapy ; Cell- and Tissue-Based Therapy
    Chemical Substances Receptors, Chimeric Antigen
    Language Chinese
    Publishing date 2023-11-15
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Efficacy and safety of fourth-generation CD19 CAR-T expressing IL7 and CCL19 along with PD-1 monoclonal antibody for relapsed or refractory large B-cell lymphoma].

    Yu, T / Liu, H / Lei, W / Chen, P P / Zhao, A Q / Yuan, X G / Gao, J M / Qian, W B

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2023  Volume 44, Issue 10, Page(s) 820–824

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Antibodies, Monoclonal/therapeutic use ; Antigens, CD19 ; Chemokine CCL19 ; Immunotherapy, Adoptive ; Interleukin-7 ; Lymphoma, Large B-Cell, Diffuse/therapy ; Programmed Cell Death 1 Receptor ; Receptors, Chimeric Antigen
    Chemical Substances Antibodies, Monoclonal ; Antigens, CD19 ; CCL19 protein, human ; cell-associated neurotoxicity ; Chemokine CCL19 ; Interleukin-7 ; Programmed Cell Death 1 Receptor ; Receptors, Chimeric Antigen
    Language Chinese
    Publishing date 2023-11-15
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Clinical characteristics and prognostic factors of 40 cases of primary systemic anaplastic large cell lymphoma].

    Chen, Y K / Yu, W J / Liu, H / Wei, J Y / Qian, W B / Jin, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2020  Volume 41, Issue 3, Page(s) 222–227

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Adult ; Aged ; Anaplastic Lymphoma Kinase ; Antineoplastic Combined Chemotherapy Protocols ; Cyclophosphamide ; Doxorubicin ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse ; Lymphoma, Large-Cell, Anaplastic ; Male ; Middle Aged ; Prednisone ; Prognosis ; Receptor Protein-Tyrosine Kinases ; Retrospective Studies ; Vincristine ; Young Adult
    Chemical Substances Vincristine (5J49Q6B70F) ; Doxorubicin (80168379AG) ; Cyclophosphamide (8N3DW7272P) ; Anaplastic Lymphoma Kinase (EC 2.7.10.1) ; Receptor Protein-Tyrosine Kinases (EC 2.7.10.1) ; Prednisone (VB0R961HZT)
    Language Chinese
    Publishing date 2020-04-13
    Publishing country China
    Document type Journal Article
    ISSN 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2020.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Efficacy and safety analysis of the zanubrutinib-based bridging regimen in chimeric antigen receptor T-cell therapy for relapsed/refractory diffuse large B-cell lymphoma].

    Lu, Y / Liu, H / Ye, S G / Zhou, L L / Luo, X / Dang, X Y / Yuan, X G / Qian, W B / Liang, A B / Li, P

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2023  Volume 44, Issue 10, Page(s) 813–819

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Middle Aged ; Receptors, Chimeric Antigen/therapeutic use ; Retrospective Studies ; Immunotherapy, Adoptive/adverse effects ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Cell- and Tissue-Based Therapy ; Antigens, CD19/adverse effects
    Chemical Substances Receptors, Chimeric Antigen ; cell-associated neurotoxicity ; zanubrutinib (AG9MHG098Z) ; Antigens, CD19
    Language Chinese
    Publishing date 2023-11-15
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Characterization and source identification of airborne trace metals in Singapore.

    Balasubramanian, R / Qian, W-B

    Journal of environmental monitoring : JEM

    2004  Volume 6, Issue 10, Page(s) 813–818

    Abstract: Airborne particulate trace metals have important health implications. As a consequence, their concentrations are increasingly monitored in many urban locations worldwide. In this study, fine atmospheric particles (PM(2.5)) were collected in Singapore ... ...

    Abstract Airborne particulate trace metals have important health implications. As a consequence, their concentrations are increasingly monitored in many urban locations worldwide. In this study, fine atmospheric particles (PM(2.5)) were collected in Singapore over a period of 83 consecutive days during 2000, and analysed to determine the concentration of trace elements using ICP-MS. Altogether, eighteen airborne trace metals were quantified: Al, Ag, Ba, Cd, Cr, Co, Cu, Fe, Ga, Li, Mn, Ni, Pb, Sr, Zn, V, Si, and Ti. While Li was the least abundant trace metal with a mean concentration of 0.2 ng m(-3), Zn showed the maximum mean concentration of 279.1 ng m(-3). Calculation of enrichment factors indicated that the elements Pb, Zn, Cd, V, Ni, Cr, and Cu were enriched by factors of 30 to 5000 relative to their natural abundance in crustal soil. The extent of metal pollution in the study area was assessed by comparing the measured concentrations to those reported in the literature for a selected number of urban sites in other parts of the world. Factor analysis was used to identify the major sources affecting particulate air pollution in Singapore. The sources that contribute to the loading of trace metal-bearing aerosols in the Singapore urban atmosphere include fuel oil-fired power plants, metal processing industry, land reclamation and construction activities, municipal solid waste incinerators, and traffic emissions.
    MeSH term(s) Acids ; Air Pollutants/analysis ; Cities ; Environmental Monitoring/statistics & numerical data ; Factor Analysis, Statistical ; Mass Spectrometry ; Metals/analysis ; Particle Size ; Singapore ; Spectrophotometry, Atomic ; Time Factors
    Chemical Substances Acids ; Air Pollutants ; Metals
    Language English
    Publishing date 2004-10
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 1453583-x
    ISSN 1464-0333 ; 1464-0325
    ISSN (online) 1464-0333
    ISSN 1464-0325
    DOI 10.1039/b407523d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Intermediate-high dose cytarabine consolidation therapy in younger adults with acute myeloid leukemia and favorable-intermediate cytogenetic risk: a retrospective study of 124 patients in a single Chinese hospital].

    Zhang, Y / Qian, J J / Wang, L / Yu, W J / Mao, L P / Tong, H Y / Meng, H T / Qian, W B / Jin, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2019  Volume 40, Issue 5, Page(s) 429–431

    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Consolidation Chemotherapy ; Cytarabine ; Cytogenetics ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Remission Induction ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Cytarabine (04079A1RDZ)
    Language Chinese
    Publishing date 2019-06-26
    Publishing country China
    Document type Journal Article
    ISSN 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2019.05.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Characterization and source identification of airborne trace metals in Singapore

    Balasubramanian, R / Qian, W-B

    Journal of environmental monitoring. 2004 Oct. 13, v. 6, no. 10

    2004  

    Abstract: Airborne particulate trace metals have important health implications. As a consequence, their concentrations are increasingly monitored in many urban locations worldwide. In this study, fine atmospheric particles (PM2.5) were collected in Singapore over ... ...

    Abstract Airborne particulate trace metals have important health implications. As a consequence, their concentrations are increasingly monitored in many urban locations worldwide. In this study, fine atmospheric particles (PM2.5) were collected in Singapore over a period of 83 consecutive days during 2000, and analysed to determine the concentration of trace elements using ICP-MS. Altogether, eighteen airborne trace metals were quantified: Al, Ag, Ba, Cd, Cr, Co, Cu, Fe, Ga, Li, Mn, Ni, Pb, Sr, Zn, V, Si, and Ti. While Li was the least abundant trace metal with a mean concentration of 0.2 ng m−3, Zn showed the maximum mean concentration of 279.1 ng m−3. Calculation of enrichment factors indicated that the elements Pb, Zn, Cd, V, Ni, Cr, and Cu were enriched by factors of 30 to 5000 relative to their natural abundance in crustal soil. The extent of metal pollution in the study area was assessed by comparing the measured concentrations to those reported in the literature for a selected number of urban sites in other parts of the world. Factor analysis was used to identify the major sources affecting particulate air pollution in Singapore. The sources that contribute to the loading of trace metal-bearing aerosols in the Singapore urban atmosphere include fuel oil-fired power plants, metal processing industry, land reclamation and construction activities, municipal solid waste incinerators, and traffic emissions.
    Keywords aerosols ; air pollution ; aluminum ; barium ; cadmium ; chromium ; cobalt ; copper ; emissions ; factor analysis ; fuels ; gallium ; incinerators ; industry ; iron ; land restoration ; lead ; lithium ; manganese ; municipal solid waste ; nickel ; particulates ; power plants ; silicon ; silver ; soil ; strontium ; titanium ; traffic ; urban areas ; vanadium ; zinc ; Singapore
    Language English
    Dates of publication 2004-1013
    Size p. 813-818.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 1453583-x
    ISSN 1464-0333 ; 1464-0325
    ISSN (online) 1464-0333
    ISSN 1464-0325
    DOI 10.1039/b407523d
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: [Prognostic significance of proteins expression by immunohistochemical method in diffuse large B cell lymphoma].

    Yu, W J / Cao, L H / Wang, J H / Wang, Z M / Qian, W B / Tong, H Y / Meng, H T / Mai, W Y / Mao, L P / Qian, J J / Jin, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2017  Volume 38, Issue 9, Page(s) 784–788

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols ; Cyclophosphamide ; Doxorubicin ; Humans ; Lymphoma, Large B-Cell, Diffuse ; Male ; Middle Aged ; Prognosis ; Proto-Oncogene Proteins c-bcl-2 ; Proto-Oncogene Proteins c-bcl-6 ; Retrospective Studies ; Rituximab ; Vincristine
    Chemical Substances Proto-Oncogene Proteins c-bcl-2 ; Proto-Oncogene Proteins c-bcl-6 ; Rituximab (4F4X42SYQ6) ; Vincristine (5J49Q6B70F) ; Doxorubicin (80168379AG) ; Cyclophosphamide (8N3DW7272P)
    Language Chinese
    Publishing date 2017-10-26
    Publishing country China
    Document type Journal Article
    ISSN 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2017.09.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Efficacy and safety analysis of different dose idarubicin plus cytarabine regimen as induction chemotherapy for young patients with de-novo acute myeloid leukemia].

    Zhang, Y / Yao, X M / Zhu, S L / Suo, S S / Mao, L P / Wei, J Y / Yu, W J / Mai, W Y / Tong, H Y / Meng, H T / Qian, W B / Jin, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2016  Volume 37, Issue 8, Page(s) 682–687

    Abstract: Objective: To compare the efficacy, safety and long-term prognosis between different dose idarubicin (IDA) combined with cytarabine (IA) as induction chemotherapy in newly diagnosed young patients of acute myeloid leukemia (AML).: Methods: A total of ...

    Abstract Objective: To compare the efficacy, safety and long-term prognosis between different dose idarubicin (IDA) combined with cytarabine (IA) as induction chemotherapy in newly diagnosed young patients of acute myeloid leukemia (AML).
    Methods: A total of 149 newly diagnosed young AML patients (APL excluded) between January 2009 to July 2014 was enrolled. According to the dose of IDA, the patients were divided into three groups, high standard- dose IA group (10- 12 mg · m (- 2) · d(- 1)), low standard-dose IA group (8-9 mg·m(-2)·d(-1)) and low-dose IA group (<8 mg·m(-2)·d(-1)). The efficacy, adverse effects and long- term prognosis among the three groups were compared.
    Results: Of them, 34 patients were in high standard-dose IA group, 53 in low standard-dose IA group and 62 in low-dose IA group. After one cycle of induction chemotherapy, the complete remission (CR) rate was 79.4%, 75.5% and 46.8%, the overall response (OR) rate was 97.1%, 94.3% and 64.5%, and the overall CR rate was 85.3%, 81.1% and 54.8%, respectively. Compared with low- dose IA group, high standard- dose IA group and low standard-dose IA group had significantly better result (P<0.05), but there was no significant difference between the latter two groups (P>0.05). Multivariate analysis also showed that standard-dose IA was favorable factor for induction chemotherapy (P<0.05). The adverse effects were similar in the three group, other than the lowest count of WBC (P=0.002). Low standard-dose IA can improve the OS compared to the low-dose IA (P=0.003), but EFS, RFS was similar in the three groups.
    Conclusions: For the newly diagnosed young(<55) AML patients, the standard-dose IA has better CR rate. The adverse effects were similar in the three groups. High-dose IA may improve the OS compared to the low-dose IA.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Cytarabine/administration & dosage ; Cytarabine/therapeutic use ; Dose-Response Relationship, Drug ; Humans ; Idarubicin/administration & dosage ; Idarubicin/therapeutic use ; Induction Chemotherapy/methods ; Leukemia, Myeloid, Acute/drug therapy ; Middle Aged ; Prognosis ; Remission Induction
    Chemical Substances Cytarabine (04079A1RDZ) ; Idarubicin (ZRP63D75JW)
    Language Chinese
    Publishing date 2016-08-24
    Publishing country China
    Document type Clinical Trial ; Journal Article
    ISSN 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2016.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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