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  1. Article ; Online: An Approach for Measuring Complexity Degree of International Engineering Projects

    Qianqian Ju / Yankun Sun / Ran Chen

    Sustainability, Vol 15, Iss 9791, p

    2023  Volume 9791

    Abstract: With the increasing trend of globalization, countries actively join the international engineering market, increasing the complexity of projects. An appropriate method for assessing project complexity can help project managers recognize the current ... ...

    Abstract With the increasing trend of globalization, countries actively join the international engineering market, increasing the complexity of projects. An appropriate method for assessing project complexity can help project managers recognize the current situation and solve problems. However, existing complexity studies ignored the contribution of human element. The impact of human activities on the complexity of socio-economic systems is concerned in the Harmony Management Theory (HMT), therefore, this study proposed a complexity measurement based on the Harmony Management Theory. Firstly, an evaluation indicator system including three dimensions of organizational, technological, and environmental complexity is proposed through a literature review, Back-Propagation Neural Network-Decision Making Trial and Evaluation Laboratory (BP-DEMATEL) method, and Interval-valued intuitionistic Fuzzy Sets (IIFS) are used to calculate complexity scores. Then, a case study of Yawan high-speed railway project is conducted to verify the effectiveness of the proposed method. The main conclusions are as follows: (1) The complexity measurement based on harmony theory can be carried out from three aspects: Organization, technology, and environment. (2) The overall complexity performance of case project is 0.52, showing a medium level. (3) Technical complexity is the most important factor of the case project. The method proposed in this study can identify the influencing factors of complexity and calculate the comprehensive evaluation value of complexity. Based on the final quantified results, managers can formulate appropriate measures and match the project with appropriate resources so as to improve the performance of International Engineering Projects (IEPs).
    Keywords international engineering projects (IEPs) ; IEPs complexity (CIEPs) ; CIEPs measurement ; project management ; Harmony Management Theory (HMT) ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Value Proposition for Enabling Construction Project Innovation by Applying Building Information Modeling

    Hui Liu / Qianqian Ju / Na Zhao / Hujun Li / Miroslaw J. Skibniewski

    Computational Intelligence and Neuroscience, Vol

    2022  Volume 2022

    Abstract: Building information modeling (BIM) is evolving as a digital infrastructure model for innovation in the construction field. The innovation-enabling potential of BIM has been highly neglected in the literature. This study explores the innovative potential ...

    Abstract Building information modeling (BIM) is evolving as a digital infrastructure model for innovation in the construction field. The innovation-enabling potential of BIM has been highly neglected in the literature. This study explores the innovative potential of BIM, specifically its value in enabling construction innovation (CI). Through reflective research and a literature review, the relationship between BIM and CI is redefined, BIM-CI’s value spectrum and underlying mechanisms are mapped and their required resources and activities are illustrated. The results indicate that different BIM applications provide various proinnovation environments wherein CI may flourish. Extra attention should be paid to BIM-enabled systematic collaborative innovation and digital innovation ecosystems with BIM as the core infrastructure that integrates the physical space with cyberspace to accelerate radical innovation. This study extends BIM management research by considering digital innovation and providing a new perspective for CI management theory and practice. The results will provide academics with a solid point of departure for developing relevant research and serve as a reference for practitioners who intend to utilize BIM for efficient innovation in construction projects.
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571
    Subject code 690
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effect of MBSR, DBT and CBT on the hypertension patients with depression/anxiety

    Yan Zhang / Hailiang Zhang / Yong Zhang / Zijiao Yang / Lingling Wang / Weimin Pan / Runjing Dai / Qianqian Ju / Dong Ren / Shisan Bao / Jingchun Fan

    PLoS ONE, Vol 18, Iss 2, p e

    Protocol of a systematic review and Bayesian network meta-analysis.

    2023  Volume 0281469

    Abstract: Introduction Hypertension, one of the most common chronic diseases worldwide, usually requires lifetime managing blood pressure (BP) with medications. Due to quite large number of hypertension patients co-exist with depression and/or anxiety, and non- ... ...

    Abstract Introduction Hypertension, one of the most common chronic diseases worldwide, usually requires lifetime managing blood pressure (BP) with medications. Due to quite large number of hypertension patients co-exist with depression and/or anxiety, and non-cooperated with medical instruction, consequently management of BP is impaired with serious complications, resulting in compromised quality of life. Consequently quality of life of such patients is impaired with serious complications. Therefore, management of depression and/or anxiety is equally important as the treatment of hypertension. Depression and/or anxiety are independent risk factors of hypertension, which is supported by the finding that there is close correlation between hypertension are depression/or anxiety. Psychotherapy (non-drug treatment) maybe useful for hypertensive patients with depression and/or anxiety to improve their negative emotions. We aim to quantify the effective of psychological therapies in the management of hypertension patients with depression or anxiety, by comparing and ranking a network meta-analysis (NMA). Materials and methods Literature search for randomized controlled trials (RCTs) will be performed in five electronic databases from inception to December 2021, including PubMed, the Cochrane library, Embase, Web of Science, and China Biology Medicine disc (CBM). The search terms mainly include "hypertension", "mindfulness-based stress reduction" (MBSR), "cognitive behavioral therapy" (CBT) and "dialectical behavior therapy" (DBT). Cochrane Collaboration quality assessment tool will be used for the risk of bias assessment. A Bayesian network meta-analysis will be performed, using WinBUGS 1.4.3, and Stata 14 will be applied to draw the network diagram, while RevMan 5.3.5 will be used to produce funnel plot for assessing the risk of publication bias. Recommended rating, development and grade methodology will also be utilized to assess the quality of evidence. Results Effect of MBSR, CBT and DBT will be evaluated by traditional ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: TAK1 Phosphorylates RASSF9 and Inhibits Esophageal Squamous Tumor Cell Proliferation by Targeting the RAS/MEK/ERK Axis

    Hui Shi / Qianqian Ju / Yinting Mao / Yuejun Wang / Jie Ding / Xiaoyu Liu / Xin Tang / Cheng Sun

    Advanced Science, Vol 8, Iss 5, Pp n/a-n/a (2021)

    2021  

    Abstract: Abstract TGF‐β‐activated kinase 1 (TAK1), a serine/threonine kinase, is a key intermediate in several signaling pathways. However, its role in tumorigenesis is still not understood well. In this study, it is found that TAK1 expression decreases in ... ...

    Abstract Abstract TGF‐β‐activated kinase 1 (TAK1), a serine/threonine kinase, is a key intermediate in several signaling pathways. However, its role in tumorigenesis is still not understood well. In this study, it is found that TAK1 expression decreases in esophageal tumor tissues and cell lines. In vitro experiments demonstrate that proliferation of esophageal tumor cells is enhanced by knockdown of TAK1 expression and attenuated by elevated expression of TAK1. Using a subcutaneous tumor model, these observations are confirmed in vivo. Based on the results from co‐immunoprecipitation coupled with mass spectrometry, Ras association domain family 9 (RASSF9) is identified as a downstream target of TAK1. TAK1 phosphorylates RASSF9 at S284, which leads to reduced RAS dimerization, thereby blocking RAF/MEK/ERK signal transduction. Clinical survey reveals that TAK1 expression is inversely correlated with survival in esophageal cancer patients. Taken together, the data reveal that TAK1‐mediated phosphorylation of RASSF9 at Ser284 negatively regulates esophageal tumor cell proliferation via inhibition of the RAS/MEK/ERK axis.
    Keywords cell proliferation ; ERK ; esophageal squamous tumor ; MEK ; RASSF9 ; TAK1 ; Science ; Q
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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