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  1. Article: "Innovation and translation of biological and biomaterial treatment for challenging musculoskeletal disorders".

    Qin, Ling

    Journal of orthopaedic translation

    2023  Volume 42, Page(s) A1–A2

    Language English
    Publishing date 2023-11-11
    Publishing country Singapore
    Document type Editorial
    ZDB-ID 2747531-1
    ISSN 2214-031X
    ISSN 2214-031X
    DOI 10.1016/j.jot.2023.10.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Conference proceedings: Proceedings of the IVth International Chestnut Symposium

    Qin, Ling

    Beijing, China, September 25 - 28, 2008

    (Acta horticulturae ; 844)

    2009  

    Institution International Society for Horticultural Science / Chestnuts Working Group
    Event/congress International Chestnut Symposium (4, 2008, Peking)
    Author's details ISHS Section Nuts and Mediterranean Climate Fruits, ISHS Working Group on Chestnuts. Convener: Qin Ling
    Series title Acta horticulturae ; 844
    Collection
    Language English
    Size 468 S. : Ill., graph. Darst., Kt.
    Publisher ISHS
    Publishing place Leuven
    Publishing country Belgium
    Document type Book ; Conference proceedings
    HBZ-ID HT016163942
    ISBN 978-90-6605-672-5 ; 90-6605-672-X
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Book: Advanced bioimaging technologies in assessment of the quality of bone and scaffold materials

    Qin, Ling

    techniques and applications

    2007  

    Author's details Ling Qin ... ed
    Keywords Bewegungsapparat ; Krankheit ; Knochen ; Knorpel ; Bildgebendes Verfahren
    Subject Bone ; Bones ; Os ; Knochengewebe ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Bewegungsorgan ; Stützapparat ; Haltungsapparat ; Bildgebendes Diagnoseverfahren ; Diagnostik ; Bilddiagnostik ; Bildgebende Methode ; Medical Imaging ; Medizinische Bildgebung ; Bildgebende Diagnostik ; Bildgebende Verfahren ; Imaging ; Knorpelgewebe ; Cartilago
    Language English
    Size XV, 700 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT015258695
    ISBN 978-3-540-45454-0 ; 3-540-45454-3
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Commentary: "Evolutionary course of the femoral head osteonecrosis: Histopathological - radiologic characteristics and clinical staging systems".

    Qin, Ling

    Journal of orthopaedic translation

    2021  Volume 31, Page(s) 139

    Language English
    Publishing date 2021-12-22
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2747531-1
    ISSN 2214-031X
    ISSN 2214-031X
    DOI 10.1016/j.jot.2021.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Splenic Infarct with Polysplenia Syndrome

    Qin Ling Zhu / Wenjun Zhu

    Journal of the Belgian Society of Radiology, Vol 106, Iss

    2022  Volume 1

    Abstract: A rare case of spontaneous splenic infarction with polysplenia is presented. The diagnosis was made by confirmed by enhanced computed tomography (CT), which showed multiple spleens in the left abdomen and one of the spleen showing low attenuation areas ... ...

    Abstract A rare case of spontaneous splenic infarction with polysplenia is presented. The diagnosis was made by confirmed by enhanced computed tomography (CT), which showed multiple spleens in the left abdomen and one of the spleen showing low attenuation areas representing infarct. Polysplenia syndrome is a rare entity associated with heterotaxy syndromes. Radiological examinations help the diagnosis by identifying infarcts in the spleen and other abnormal organs in the chest and abdomen. Teaching Point: We report a rare case of polysplenic syndrome with splenic infarction.
    Keywords polysplenia syndrome ; isomerism ; abdominal computed tomography ; splenic infarction ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Ubiquity Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Splenic Infarct with Polysplenia Syndrome.

    Zhu, Qin Ling / Zhu, Wenjun

    Journal of the Belgian Society of Radiology

    2022  Volume 106, Issue 1, Page(s) 60

    Abstract: A rare case of spontaneous splenic infarction with polysplenia is presented. The diagnosis was made by confirmed by enhanced computed tomography (CT), which showed multiple spleens in the left abdomen and one of the spleen showing low attenuation areas ... ...

    Abstract A rare case of spontaneous splenic infarction with polysplenia is presented. The diagnosis was made by confirmed by enhanced computed tomography (CT), which showed multiple spleens in the left abdomen and one of the spleen showing low attenuation areas representing infarct. Polysplenia syndrome is a rare entity associated with heterotaxy syndromes. Radiological examinations help the diagnosis by identifying infarcts in the spleen and other abnormal organs in the chest and abdomen.
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2834839-4
    ISSN 2514-8281
    ISSN 2514-8281
    DOI 10.5334/jbsr.2685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Glioblastoma patients' survival and its relevant risk factors during the pre- and post-COVID-19 pandemic: Real-world cohort study in the USA and China.

    Qin, Ling / Li, Haoyi / Zheng, Dao / Lin, Song / Ren, Xiaohui

    International journal of surgery (London, England)

    2024  

    Abstract: Background: Although the coronavirus disease 2019 (COVID-19) pandemic has exerted potential impact on patients with glioblastomas (GBMs), it remains unclear whether the survival and its related risk factors of GBM patients would be altered or not during ...

    Abstract Background: Although the coronavirus disease 2019 (COVID-19) pandemic has exerted potential impact on patients with glioblastomas (GBMs), it remains unclear whether the survival and its related risk factors of GBM patients would be altered or not during the period spanning from pre- to post- COVID-19 pandemic era. This study aimed to clarify the important issues above.
    Methods: Two observational cohorts were utilized, including the nationwide American cohort from the Surveillance, Epidemiology, and End-Results (SEER) and the Chinese glioblastoma cohort (CGC) at our institution during 2018-2020. Demographics, tumor features, treatment regimens and clinical outcomes were collected. Cox regression model, competing risk model, and subgroup and sensitivity analysis were used to dynamically estimate the survival and its relevant risk factors over different diagnosis years from the pre- (2018 and 2019) to post-COVID-19 (2020) pandemic. Causal mediation analysis was further adopted to explore the potential relationship between risk factors and mortality.
    Results: This study included 11321 GBM cases in SEER and 226 GBM patients in CGC, respectively. Instead of the diagnostic years of 2018-2020, the prognostic risk factors, such as advanced age, bilateral tumor and absence of comprehensive therapy (surgery combined with chemoradiotherapy), were identified to persistently affect GBM survival independently during the period from 2018 to 2020 in the SEER cohort (all P < 0.05). In CGC, lack of comprehensive therapy for GBM patients were restated as survival risk factors during the same timeframe. Causal mediation analysis showed that the effect of comprehensive therapy on all-cause mortality played a determinant role (direct effect value -0.227, 95% confidence interval -0.248 to -0.207), which was partially mediated by age (9.11%) rather than tumor laterality.
    Conclusions: As the timeframe shifted from pre- to post-COVID-19 pandemic, survival of GBM patients remained stable, yet advanced age, bilateral tumors, and passive treatment continuingly impacted GBM survival. It is necessary to optimize the comprehensive treatment for GBM patients even in the post-pandemic era.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000001224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Influence of Dyadic Coping Model on Anxiety and Depression Level and Treatment Compliance in Glaucoma Patients.

    Cheng, Jinming / Sun, Wenmin / Yu, Chaoxia / Zhang, Wenhong / Qin, Ling

    Alternative therapies in health and medicine

    2024  

    Abstract: Objective: To investigate the influence of the dyadic coping model on anxiety and depression levels and treatment compliance in glaucoma patients.: Methods: According to the random number table method, 80 glaucoma patients were assigned into an ... ...

    Abstract Objective: To investigate the influence of the dyadic coping model on anxiety and depression levels and treatment compliance in glaucoma patients.
    Methods: According to the random number table method, 80 glaucoma patients were assigned into an observation group and a control group, with 40 cases in each group are recruited from January 2021 to February 2022. Both groups received routine preoperative glaucoma care; in addition, the observation group received a 10-week dyadic coping model intervention. The dyadic coping model is a therapeutic approach that involves the collaborative efforts of both patients and their close partners or caregivers to cope with stressors and challenges related to the perioperative period. The baseline data questionnaires were collected before the intervention, and the outcome was evaluated 10 weeks later using the Anxiety and Depression Self-Rating Scale and the Treatment Compliance Scale.
    Results: After intervention, the treatment compliance of glaucoma in the observation group was significantly better than that in the control group, and the anxiety and depression level in the observation group was significantly lower than that in the control group (P < .05).
    Conclusion: The dyadic coping model intervention for glaucoma patients can successfully increase treatment compliance and lower anxiety and depression levels.
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Intestinal Microbiota Modulates the Antitumor Effect of Oncolytic Virus Vaccines in Colorectal Cancer.

    Chen, Xia / Wang, Guanjun / Qin, Ling / Hu, Bing / Li, Jun

    Digestive diseases and sciences

    2024  Volume 69, Issue 4, Page(s) 1228–1241

    Abstract: Background: Immunotherapies, such as oncolytic viruses, have become powerful cancer treatments, but only some patients with cancer can benefit from them, especially those with advanced-stage cancer, and new therapeutic strategies are needed to ... ...

    Abstract Background: Immunotherapies, such as oncolytic viruses, have become powerful cancer treatments, but only some patients with cancer can benefit from them, especially those with advanced-stage cancer, and new therapeutic strategies are needed to facilitate extended survival. The intestinal microbiota may contribute to colorectal cancer (CRC) carcinogenesis and the response to immunotherapy. However, whether and how the intestinal microbiota modulates the effects of oncolytic virus vaccines (OVVs) in CRC remain to be investigated.
    Methods: We generated an MC38-gp33 CRC mouse model and treated it with OVV-gp33 in early and advanced stages. Probiotics, fecal microbiota transplantation (FMT), and antibiotics (ABX) were administered to regulate the microbial composition of CRC mice at an advanced stage. The tumor growth rate and survival time of the mice were recorded; 16S rDNA sequencing was used to analyze the microbial composition and flow cytometry was used to detect T-cell subset activity.
    Results: OVV-gp33 treatment inhibited tumor growth and prolonged survival in the early stage of CRC but did not have a significant effect on the advanced stage of CRC. Moreover, 16S rDNA sequence analysis and flow cytometry showed significant differences in intestinal microbiota composition, microbial metabolites, and T-cell subsets in early and advanced-stage CRC. Probiotic and FMT treatment significantly enhanced the antitumor effect of OVV in the advanced stage of CRC with an increased abundance of activated CD8
    Conclusions: These results indicate that the intestinal microbiota and microbial metabolites play an important role in the antitumor effect of OVV in CRC. Furthermore, altering the intestinal microbiota composition can modulate the antitumor and immunomodulatory effects of OVV in CRC.
    MeSH term(s) Humans ; Animals ; Mice ; Oncolytic Viruses/genetics ; Gastrointestinal Microbiome/physiology ; CD8-Positive T-Lymphocytes/metabolism ; Colorectal Neoplasms/pathology ; DNA, Ribosomal/pharmacology
    Chemical Substances DNA, Ribosomal
    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-024-08346-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: 8例散发儿童肉毒中毒的临床特点及神经电生理分析.

    Peng, Qin-Ling / Wang, Ping / Hu, Nan

    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

    2023  Volume 25, Issue 9, Page(s) 936–940

    Abstract: Objectives: To study the clinical and neuroelectrophysiological features of botulism in children.: Methods: A retrospective analysis was conducted on the clinical data of eight children who were diagnosed with botulism in the Department of Neurology, ...

    Title translation Clinical and neuroelectrophysiological features of botulism in children: an analysis of eight sporadic cases.
    Abstract Objectives: To study the clinical and neuroelectrophysiological features of botulism in children.
    Methods: A retrospective analysis was conducted on the clinical data of eight children who were diagnosed with botulism in the Department of Neurology, Hunan Children's Hospital, from August 2015 to October 2022.
    Results: All eight children were found to have symmetrical cranial nerve palsy and flaccid paralysis of the extremities, with a descending pattern. Seven children presented with respiratory muscle paralysis. Electrophysiological examinations revealed decreased compound muscle action potential (CMAP) amplitudes in 5 children, increased CMAP amplitudes exceeding 40.0% in 6 children during high-frequency repetitive nerve stimulation, and short duration, low amplitude, and polyphasic motor unit action potentials in 4 children.
    Conclusions: The main clinical features of botulism in children include symmetric, descending flaccid paralysis starting from cranial nerves, with the possibility of respiratory muscle paralysis. Electrophysiological abnormalities associated with it include decreased CMAP amplitudes, increased CMAP amplitudes during high-frequency repetitive nerve stimulation, and short duration, low amplitude, and polyphasic motor unit action potentials.
    Language Chinese
    Publishing date 2023-09-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1008-8830
    ISSN 1008-8830
    DOI 10.7499/j.issn.1008-8830.2304019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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