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Article ; Online: Relationship between Financial Asset Allocation, Leverage Ratio, and Risk-Taking of Small- and Medium-Sized Enterprises in China

Qing Chen

Journal of Environmental and Public Health, Vol

Taking Environment-Related Industries as an Example

2022 Volume 2022

Abstract: With the improvement of environmental policies and industry requirements for enterprise production and management, small- and medium-sized enterprises in environment-related industries were also changing. It was known from the existing research that the ... ...

Abstract	With the improvement of environmental policies and industry requirements for enterprise production and management, small- and medium-sized enterprises in environment-related industries were also changing. It was known from the existing research that the investment allocation of assets of small- and medium-sized enterprises was closely related to risk and return, and the leverage ratio of enterprises affected the risk-taking level of enterprises. In the process of sustainable development, enterprises will inevitably bear certain risks, but excessive risk-taking will bring all kinds of uncertainty and bankruptcy risk to the expected income and future cash flow of enterprises. Therefore, taking small- and medium-sized enterprises in environment-related industries as an example, this paper put forward relevant assumptions by analyzing the interaction between the existing enterprise financial asset allocation, risk-taking level and leverage ratio. In order to facilitate empirical analysis, A-share listed companies in environment-related industries in Shanghai and Shenzhen stock exchanges, small- and medium-sized board and GEM listed companies in Shenzhen stock exchange from 2007 to 2019 were selected as research samples. These data came from the information open platform for small- and medium-sized enterprises in environment-related industries, the research reports of third-party consulting companies and CSMAR and Wind databases. The empirical results showed that the allocation of financial assets had a significant impact on the level of risk-taking, and there was a U-shaped relationship between them when other conditions remained unchanged. At the same time, the financial asset allocation of small- and medium-sized enterprises in Chinese environment-related industries had a significant impact on the enterprise leverage ratio. Under other conditions unchanged, there was a U-shaped relationship between the two. In addition, leverage played an intermediary role in the relationship between financial asset allocation and ...
Keywords	Public aspects of medicine ; RA1-1270
Subject code	332
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Two faces: IL-22 effects prevail over defense against metastasis.

Qing, Chen / Ghorani, Ehsan

Immunity

2023 Volume 56, Issue 1, Page(s) 6–8

Abstract: Interleukin-22 (IL-22) is a cytokine with pleotropic and opposing roles in physiological and pathological states. In this issue of Immunity, Giannou et al. and Briukhovetska et al. demonstrate how IL-22 is involved in promoting cancer metastasis ... ...

Abstract	Interleukin-22 (IL-22) is a cytokine with pleotropic and opposing roles in physiological and pathological states. In this issue of Immunity, Giannou et al. and Briukhovetska et al. demonstrate how IL-22 is involved in promoting cancer metastasis formation.
MeSH term(s)	Interleukins ; Cytokines ; Interleukin-22
Chemical Substances	Interleukins ; Cytokines
Language	English
Publishing date	2023-01-11
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	1217235-2
ISSN	1097-4180 ; 1074-7613
ISSN (online)	1097-4180
ISSN	1074-7613
DOI	10.1016/j.immuni.2022.12.013
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Article ; Online: Analysis of the miRNA-mRNA Regulatory Network Reveals the Biomarker Genes in the Progression of Myocardial Ischemic Reperfusion

Nini Li / Qing Chen

Journal of Healthcare Engineering, Vol

2022 Volume 2022

Abstract: Objective. Cardiac injury induced by myocardial ischemic reperfusion (MI/R) is still an intractable question in clinical, and it has been confirmed as a major reason for the development of cardiovascular disease. Bioinformatics analysis has been widely ... ...

Abstract	Objective. Cardiac injury induced by myocardial ischemic reperfusion (MI/R) is still an intractable question in clinical, and it has been confirmed as a major reason for the development of cardiovascular disease. Bioinformatics analysis has been widely used for revealing the pathogenic mechanism of diseases. This study attempted to identify the biomarkers and reveal the regulation mechanism of MI/R injury via bioinformatics analysis. Methods. The GSE67308 and GSE74951 were obtained from the GEO database. The datasets were analyzed with GEO2R tool, and the genes with \|logFC\| > 2 and p value <0.05 were identified as the differentially expressed genes (DEGs). The enrichment analysis of the DEGs was performed with the DAVID database and R language. Moreover, the protein-protein interaction (PPI) network of DEGs was performed with the STRING database and then visualized with Cytoscape. Result. The results showed that 195 downregulated mRNAs and 240 downregulated mRNAs were found in GSE67308, and 11 miRNAs were found in GSE7495. 152 common genes were screened in DEGs of GSE67308 and the targets of 11 miRNAs in GSE7495. Moreover, the enrichment analysis showed that the common genes were related with inflammatory response, immune response, PI3K/AKT, NF-κB, and TNF pathways. Besides, mmu-miR-92a-3p and mmu-miR-27b-3p were identified as the hubs miRNAs, and TNF, IL1B, and IFG1 were screened as the key nodes. Conclusion. This study established a miRNA-mRNA network for cardiac injury induced by MI/R and provided the evidence concerning the molecular mechanism of MI/R injury, which provided some reference for MI/R treatment.
Keywords	Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
Subject code	610
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Unexpected discovery of Clonorchis sinensis by common bile duct exploration

Ping Shao / Qing Chen

Clinical Case Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)

2022

Abstract: Abstract Coexisting choledocholithiasis and Clonorchis sinensis infection are relatively rare. We report a 39‐year‐old patient with choledocholithiasis who inadvertently found Clonorchis sinensis during common bile duct exploration. Our experience ... ...

Abstract	Abstract Coexisting choledocholithiasis and Clonorchis sinensis infection are relatively rare. We report a 39‐year‐old patient with choledocholithiasis who inadvertently found Clonorchis sinensis during common bile duct exploration. Our experience suggests that if preoperative imaging reveals nonspecific changes associated with choledocholithiasis, the possibility of biliary parasite infection should be suspected.
Keywords	choledocholithiasis ; Clonorchis sinensis ; Medicine ; R ; Medicine (General) ; R5-920
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Thesis: Tyrosine phosphorylation and regulation of Wnt co-receptor LRP6

Chen, Qing

2014

Author's details	[presented by Qing Chen]
Subject code	571.74
Language	English
Size	113 S. : Ill., graph. Darst.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Heidelberg, Univ., Diss., 2014
HBZ-ID	HT018444887
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2014 E 1511	order for loan	Magazin

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Article ; Online: Immersed Boundary Methods for Simulations of Biological Flows in Swimming and Flying Bio-Locomotion

Yuhang Zeng / Yan Wang / Dangguo Yang / Qing Chen

Applied Sciences, Vol 13, Iss 4208, p

A Review

2023 Volume 4208

Abstract: Biological flows in swimming and flying bio-locomotion usually involve intricate flexible or rigid structures that undergo large deformations and displacements, as well as rich mechanisms of bio-fluid interactions. Immersed boundary methods (IBMs) have ... ...

Abstract	Biological flows in swimming and flying bio-locomotion usually involve intricate flexible or rigid structures that undergo large deformations and displacements, as well as rich mechanisms of bio-fluid interactions. Immersed boundary methods (IBMs) have gained increasing prevalence in numerical investigations of such biological flow problems due to their simplicity and capability for simulating these problems on a Cartesian mesh, which does not require tedious grid-regeneration or mesh deformation processes. In recent years, the vigorous development of IBM variants has enriched numerical techniques for bionic simulations. This review focuses on the development of the IBM and its applications in the field of biological aerodynamics and hydrodynamics, including both diffuse and sharp interface IBMs. The fundamentals of the former are introduced in detail, and the hybrid Cartesian-IBM is briefly presented as one representative method of the latter. In particular, the velocity correction IBM is highlighted in the diffuse interface IBM due to its superiority in accurately satisfying no-slip boundary conditions. To shed light on the dynamic characteristics of flying and swimming behaviors with predefined or passive motion and deformation, some recent results from IBM applications are also presented. Finally, this review discusses some challenges and promising techniques in the research of bio-inspired motions based on the IBM.
Keywords	immersed boundary method ; biological flows ; swimming and flying ; fluid–structure interaction ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	612
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preparation of MnO 2 -Carbon Materials and Their Applications in Photocatalytic Water Treatment

Kun Fan / Qing Chen / Jian Zhao / Yue Liu

Nanomaterials, Vol 13, Iss 541, p

2023 Volume 541

Abstract: Water pollution is one of the most important problems in the field of environmental protection in the whole world, and organic pollution is a critical one for wastewater pollution problems. How to solve the problem effectively has triggered a common ... ...

Abstract	Water pollution is one of the most important problems in the field of environmental protection in the whole world, and organic pollution is a critical one for wastewater pollution problems. How to solve the problem effectively has triggered a common concern in the area of environmental protection nowadays. Around this problem, scientists have carried out a lot of research; due to the advantages of high efficiency, a lack of secondary pollution, and low cost, photocatalytic technology has attracted more and more attention. In the past, MnO 2 was seldom used in the field of water pollution treatment due to its easy agglomeration and low catalytic activity at low temperatures. With the development of carbon materials, it was found that the composite of carbon materials and MnO 2 could overcome the above defects, and the composite had good photocatalytic performance, and the research on the photocatalytic performance of MnO 2 -carbon materials has gradually become a research hotspot in recent years. This review covers recent progress on MnO 2 -carbon materials for photocatalytic water treatment. We focus on the preparation methods of MnO 2 and different kinds of carbon material composites and the application of composite materials in the removal of phenolic compounds, antibiotics, organic dyes, and heavy metal ions in water. Finally, we present our perspective on the challenges and future research directions of MnO 2 -carbon materials in the field of environmental applications.
Keywords	water pollution ; MnO 2 -carbon materials ; photocatalytic ; environmental applications ; Chemistry ; QD1-999
Subject code	333
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Digital Government Development, Local Governments’ Attention Distribution and Enterprise Total Factor Productivity

Enji Li / Qing Chen / Xinyan Zhang / Chen Zhang

Sustainability, Vol 15, Iss 2472, p

Evidence from China

2023 Volume 2472

Abstract: Building digital government is an important means for the government to improve the public service ability and optimize the business environment, which directly affects the production and operation activities of micro-enterprises. Based on the panel data ...

Abstract	Building digital government is an important means for the government to improve the public service ability and optimize the business environment, which directly affects the production and operation activities of micro-enterprises. Based on the panel data of listed enterprises and municipal government portal website performance in China, this paper empirically investigates the impact of digital government development on enterprise total factor productivity (TFP) and the moderating effect of the local government’s attention distribution. The research results showed that digital government development significantly improved the enterprise TFP, and this conclusion remained unchanged after a series of robustness tests using instrumental variables, one-stage lag of explained variables, and debiased machine learning models. We also found that the greater the pressure faced by local governments and the longer the chief officials’ tenure, the more attention local governments paid to building digital government, and the more obvious the role of digital government development in promoting enterprise TFP. Heterogeneity test results showed that the information disclosure, online service, and public participation all had a positive effect on enterprise TFP, while the user experience had no effect on it. Digital government development had a more obvious role in promoting enterprise TFP of central and western regions, non-SOEs, and technology-intensive enterprises. Moreover, reducing enterprise rent-seeking, attracting new enterprise entry, and increasing enterprise R&D investment are important mechanisms for digital government development to improve enterprise TFP.
Keywords	digital government development ; enterprise TFP ; attention distribution ; business environment ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	950
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of diet shift on the gut microbiota of the critically endangered Siberian Crane

Wenjuan Wang / Yafang Wang / Qing Chen / Huifang Ding

Avian Research, Vol 14, Iss , Pp 100108- (2023)

2023

Abstract: Wetlands worldwide have suffered from serious degradation and transformation, leading to waterbirds increasingly dependent on agricultural fields for feeding. Although gut microbiota is an essential component of host health, the impacts of agricultural ... ...

Abstract	Wetlands worldwide have suffered from serious degradation and transformation, leading to waterbirds increasingly dependent on agricultural fields for feeding. Although gut microbiota is an essential component of host health, the impacts of agricultural feeding on gut microbial community and pathogen transmission remain poorly understood. To fill this knowledge gap, we used 16S rRNA sequencing to characterize the fecal bacterial community of the Siberian Crane (Grus leucogeranus), a Critically Endangered species, that recently has shifted its foraging from largely Vallisneria tubers in Poyang Lake natural wetlands to crops (i.e., rice seeds and lotus rhizomes) in agricultural fields. We compared the bacterial communities between tuber foraging cranes and crop foraging cranes. Our results indicate that diet shift greatly modified the gut microbiota diversity, composition and function. Crop foraging cranes had higher microbiota diversity than tuber foraging cranes. The alteration in microbiota composition and function were correlated with change in food nutrition. Tuber (i.e., high in fiber) foraging cranes were enriched in Clostridiaceae with fiber digestion ability, and crop (i.e., high in carbohydrate) foraging cranes were enriched in bacterial taxa and functions related to carbohydrate metabolism. The flexibility of gut microbiota might enhance Siberian Cranes’ ability to adapt to novel diet and environment. However, many enriched families in crop foraging cranes were pathogenic bacteria, which might increase the susceptibility of cranes to pathogenic infection. Special caution should be taken to agricultural feeding waterbirds in Asia, where the widespread poultry-keeping in over-harvested rice fields might increase the transmission probability of pathogenetic bacteria among wild birds, domestic poultry and humans.
Keywords	Diet shift ; Pathogenic bacteria ; Poyang Lake ; Siberian Crane ; Vallisneria tuber ; Wetland degradation ; Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Efficacy and Safety of Bariatric Surgery in Dutch People Living with HIV: a Retrospective Matched Cohort Analysis.

Zino, Leena / Qing Chen, Rou / Deden, Laura / Hazebroek, Eric / Richel, Olivier / Colbers, Angela / Burger, David M

Obesity surgery

2024 Volume 34, Issue 5, Page(s) 1584–1589

Abstract: Purpose: Obesity is rising among people with HIV (PLWH), sparking interest in bariatric surgery (BS) for this group. Yet, large-scale comparative research on BS outcomes in PLWH is lacking.: Methods: We performed a retrospective, matched cohort ... ...

Abstract	Purpose: Obesity is rising among people with HIV (PLWH), sparking interest in bariatric surgery (BS) for this group. Yet, large-scale comparative research on BS outcomes in PLWH is lacking. Methods: We performed a retrospective, matched cohort analysis in PLWH and HIV uninfected controls. Subjects were retrieved from the Dutch Audit for Treatment of Obesity (DATO) registry. Matching (1:7 ratio) included age (± 5-years), sex, body-mass index (BMI) of ± 3 kg/m Results: Twenty-seven PLWH and 168 controls were included. At 1-year post-BS, 89% PLWH achieved ≥ 20%TWL, compared to 94% of controls (p = 0.4). Cumulative %TWL at 2-years post-BS were 82% and 92% in PLWH and controls, respectively (p = 0.2). Improvement rates in hypertension and type 2 diabetes mellitus were 50% and 86% in PLWH, versus 87% and 87% in controls. Full remission occurred in 20% and 71% of PLHIV, versus 49% and 44% of controls, respectively. No improvement or remission was observed for dyslipidaemia in PLHIV compared to 54% improvement and 29% remission in controls. Surgical complications were 0% in PLHIV and 13% (n = 21) in controls. Conclusion: Efficacy and safety outcomes of BS were similar between PLWH and controls except for the lack of improvement in dyslipidaemia in PLWH.
MeSH term(s)	Humans ; Retrospective Studies ; Obesity, Morbid/surgery ; Diabetes Mellitus, Type 2/surgery ; HIV ; Bariatric Surgery ; Obesity/surgery ; Cohort Studies ; HIV Infections/complications ; HIV Infections/epidemiology ; HIV Infections/surgery ; Dyslipidemias/epidemiology ; Dyslipidemias/surgery ; Dyslipidemias/complications ; Treatment Outcome ; European People
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-024-07126-3
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