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Article ; Online: Study on a horizontal axial flow pump during runaway process with bidirectional operating conditions

Kan Kan / Qingying Zhang / Zhe Xu / Huixiang Chen / Yuan Zheng / Daqing Zhou / Maxima Binama

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 21

Abstract: Abstract The ultra-low head pump stations often have bidirectional demand of water delivery, so there is a risk of runaway accident occurring in both conditions. To analyze the difference of the runaway process under forward runaway condition (FRC) and ... ...

Abstract	Abstract The ultra-low head pump stations often have bidirectional demand of water delivery, so there is a risk of runaway accident occurring in both conditions. To analyze the difference of the runaway process under forward runaway condition (FRC) and backward runaway condition (BRC), the whole flow system of a horizontal axial flow pump is considered. The Shear-Stress Transport (SST) k–ω model is adopted and the volume of fluid (VOF) model is applied to simulate the water surface in the reservoirs. Meanwhile, the torque balance equation is introduced to obtain the real time rotational speed, then the bidirectional runaway process of the pump with the same head is simulated. In addition, the vortex transport equation and swirl number are proposed to reveal the flow characteristics during the runaway process. The results show that the runaway process can be divided into five stages: the drop, braking, rising, convergence and runaway stages, according to the changing law of torque curve. In the rising stage, the pressure difference on the blade surface continues to increase, which contributes to the abnormal torque increase. In this stage, the flow hits the pressure surface (PS) at a faster speed enlarging the pressure on PS, and the flow separation takes place on the suction surface (SS) weakening the pressure on SS. During the convergence and runaway stage, the pulsation amplitude of torque and axial force under FRC is obviously larger than those under BRC. This is because the rotation frequency of the vortex rope is the same as main pressure fluctuation frequency in impeller under FRC, which enhances the pulsation amplitude. Whereas the vortices are broken due to the inhibitive effect from guide vanes under BRC.
Keywords	Medicine ; R ; Science ; Q
Subject code	660
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The tibetan medicine Zuozhu-Daxi can prevent Helicobacter pylori induced-gastric mucosa inflammation by inhibiting lipid metabolism

Yanyan Shi / Jing Ning / Kelsang Norbu / Xingzi Hou / Huiling Zheng / Hejun Zhang / Wei Yu / Feng Zhou / Yuan Li / Shigang Ding / Qingying Zhang

Chinese Medicine, Vol 17, Iss 1, Pp 1-

2022 Volume 15

Abstract: Abstract Background Tibetan medicine has been used in clinical practice for more than 3800 years. Zuozhu-Daxi (ZZDX), a classic traditional Tibetan medicine, has been proved to be effective in the treatment of digestive diseases, such as chronic ... ...

Abstract	Abstract Background Tibetan medicine has been used in clinical practice for more than 3800 years. Zuozhu-Daxi (ZZDX), a classic traditional Tibetan medicine, has been proved to be effective in the treatment of digestive diseases, such as chronic gastritis, gastric ulcer, etc. Helicobacter pylori (H. pylori), one of the most common pathogenic microbes, is regarded as the most common cause of gastritis. Researching on the effects of ZZDX on H. pylori-induced gastric mucosa inflammation could provide more evidences on H. pylori treatment and promote the development of Tibetan medicine. This study aimed to explore whether ZZDX could rescue H. pylori-induced gastric mucosa inflammation and its mechanism. Methods Male C57BL/6 mice were infected with H. pylori, and orally treated with ZZDX to rescue gastric mucosa inflammation induced by H. pylori infection. Pathology of gastric mucosa inflammation was evaluated under microscopy by hematoxylin–eosin (HE) staining. The infection status of H. pylori was evaluated by immunohistochemical (IHC) staining. The reactive oxygen species (ROS) level in serum was evaluated using a detection kit. IL-1α, IL-6, and PGE2 expression levels in serum were measured using ELISA. IL-1α, IL-8, TNF-α, and NOD1 expression levels in gastric tissues were measured using real-time PCR. RNA sequencing and gene certification of interest were performed to explore the mechanisms in vivo and in vitro. Results The results showed that ZZDX could significantly inhibit H. pylori-induced gastric mucosa inflammation using HE staining. IL-1α, IL-6, and PGE2 expression levels in serum were significantly decreased after treatment with ZZDX. ZZDX treatment significantly decreased the mRNA expression of IL-8 induced by H. pylori infection in gastric tissues. Elovl4, Acot1 and Scd1 might be involved in the mechanisms of ZZDX treatment. However, the H. pylori infection status in the gastric mucosa was not reduced after ZZDX treatment. Conclusions ZZDX reversed gastric mucosal injury and alleviated gastric mucosa ...
Keywords	Tibetan medicine ; Zuozhu-Daxi ; Helicobacter pylori ; Gastric mucosal injury ; Gastric mucosal inflammation ; Other systems of medicine ; RZ201-999
Subject code	570
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Simultaneous remediation of As(III) and dibutyl phthalate (DBP) in soil by a manganese-oxidizing bacterium and its mechanisms

He, Zhanfei / Jia Duo / Qingying Zhang / Xiangliang Pan / Zeya Li / Zhen Wei

Chemosphere. 2019 Apr., v. 220

2019

Abstract: Soils are experiencing increasing pollution with arsenic (As) and phthalate esters (PAEs), which is threatening human health. In this study, the feasibility of simultaneous remediation of soil As(III) and a PAE, dibutyl phthalate (DBP), by a manganese- ... ...

Abstract	Soils are experiencing increasing pollution with arsenic (As) and phthalate esters (PAEs), which is threatening human health. In this study, the feasibility of simultaneous remediation of soil As(III) and a PAE, dibutyl phthalate (DBP), by a manganese-oxidizing bacterium (MnOB) was evaluated. As immobilization and DBP degradation were simultaneously enhanced by MnOB addition. The effects of initial concentrations of As(III), DBP, and Mn(II), and moisture content on the removal of As(III) and DBP were investigated. The results indicated that there was a competitive interaction between As(III) and DBP removal, and 40 mg/kg of Mn(II) dosage and 20%–30% soil moisture content were recommended for optimal and simultaneous removal of As(III) and DBP. Microbial community analysis revealed that community structure and diversity were not changed significantly by MnOB addition. Taken together, the findings from this study indicated that DBP was degraded primarily by microorganisms, whereas As(III) was removed largely by biogenic Mn oxides and immobilized by adsorption onto Mg/Fe oxides and/or formation of metal arsenate precipitates/co-precipitates. This study offers a novel and high-efficiency strategy to remediate the combined contamination of As and PAEs in soils.
Keywords	adsorption ; arsenates ; arsenic ; bacteria ; community structure ; dibutyl phthalate ; human health ; iron oxides ; magnesium ; manganese ; manganese oxides ; microbial communities ; pollution ; remediation ; soil water content ; water content
Language	English
Dates of publication	2019-04
Size	p. 837-844.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2018.12.213
Database	NAL-Catalogue (AGRICOLA)

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Article: Microbiological and environmental significance of metal-dependent anaerobic oxidation of methane

He, Zhanfei / Geoffrey Michael Gadd / Hongwei Luo / Qingying Zhang / Xiangliang Pan / Yudong Feng

Science of the total environment. 2018 Jan. 01, v. 610-611

2018

Abstract: Anaerobic oxidation of methane (AOM) can be coupled to the reduction of sulfate, nitrate and nitrite, which effectively reduces methane emission into the atmosphere. Recently, metal-dependent AOM (metal-AOM, AOM coupled to metal reduction) was ... ...

Abstract	Anaerobic oxidation of methane (AOM) can be coupled to the reduction of sulfate, nitrate and nitrite, which effectively reduces methane emission into the atmosphere. Recently, metal-dependent AOM (metal-AOM, AOM coupled to metal reduction) was demonstrated to occur in both environmental samples and enrichment cultures. Anaerobic methanotrophs are capable of respiration using Fe(III) or Mn(IV), whether they are in the form of soluble metal species or insoluble minerals. Given the wide distribution of Fe(III)/Mn(IV)-bearing minerals in aquatic methane-rich environments, metal-AOM is considered to be globally important, although it has generally been overlooked in previous studies. In this article, we discuss the discovery of this process, the microorganisms and mechanisms involved, environmental significance and factors influencing metal-AOM. Since metal-AOM is poorly studied to date, some discussion is included on the present understanding of sulfate- and nitrate-AOM and traditional metal reduction processes using organic substrates or hydrogen as electron donors. Metal-AOM is a relatively new research field, and therefore more studies are needed to fully characterize the process. This review summarizes current studies and discusses the many unanswered questions, which should be useful for future research in this field.
Keywords	hydrogen ; iron ; manganese ; methane ; methane production ; methanotrophs ; minerals ; nitrates ; nitrites ; oxidation ; sulfates
Language	English
Dates of publication	2018-0101
Size	p. 759-768.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2017.08.140
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 949: Show issues

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Article: Structurally diverse glycoconjugated volatile compounds from Oxytropis falcata Bunge

Wang, Shanshan / Hong Liang / Pengfei Tu / Qingying Zhang / Sheng Que / Xiaojing Zhang

Phytochemical Society of Europe Phytochemistry letters. 2018 Oct., v. 27

2018

Abstract: A phytochemical investigation on the whole plant of Oxytropis falcata Bunge yielded 16 glycoconjugated compounds with structurally diverse volatile aglycones but similar sugars. Of these, five were previously undescribed compounds with different volatile ...

Abstract	A phytochemical investigation on the whole plant of Oxytropis falcata Bunge yielded 16 glycoconjugated compounds with structurally diverse volatile aglycones but similar sugars. Of these, five were previously undescribed compounds with different volatile aglycones but same glucuronic acid (1 → 2) glucosyl moiety, including three octanol glucuronic acid (1 → 2) glucosides (1–3), one acyclic monoterpenoid glucuronic acid (1 → 2) glucoside (4), and one 4-phenyl-butan-2-ol glucuronic acid (1 → 2) glucoside (5), and 11 were biological related known glucoconjugated volatile compounds (6–16) isolated from genus Oxytropis for the first time. The structures of these compounds were determined by extensive spectroscopic analysis of MS, 1D and 2D NMR data. The absolute configurations of aglycones and sugar residues were assigned via enzymatic hydrolysis and subsequently comparison of the specific rotations. This is the first report of such structurally diverse glycoconjugated volatile compounds from O. falcata, which might be regarded as the precursor of free volatile compounds, and presents scientific evidences for better clarifying the volatile compositions of this medicinal plant and genus Oxytropis.
Keywords	chemical constituents of plants ; enzymatic hydrolysis ; glucosides ; glucuronic acid ; medicinal plants ; moieties ; monoterpenoids ; nuclear magnetic resonance spectroscopy ; octanol ; Oxytropis ; spectral analysis ; volatile compounds
Language	English
Dates of publication	2018-10
Size	p. 143-147.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	1874-3900
DOI	10.1016/j.phytol.2018.07.015
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Oxytrodiflavanone A and Oxytrochalcoflavanones A,B

Yang Liu / Norbo Kelsang / Jianghai Lu / Yingtao Zhang / Hong Liang / Pengfei Tu / Dexin Kong / Qingying Zhang

Molecules, Vol 24, Iss 8, p

New Biflavonoids from Oxytropis chiliophylla

2019 Volume 1468

Abstract: Three previously undescribed biflavonoids, oxytrodiflavanone A ( 1 ), and oxytrochalcoflavanones A,B ( 2 , 3 ), were isolated from the aerial part of Oxytropis chiliophylla , together with their putative biosynthetic monomers, i.e., (2 S )-5,7- ... ...

Abstract	Three previously undescribed biflavonoids, oxytrodiflavanone A ( 1 ), and oxytrochalcoflavanones A,B ( 2 , 3 ), were isolated from the aerial part of Oxytropis chiliophylla , together with their putative biosynthetic monomers, i.e., (2 S )-5,7-dihydroxyflavanone ( 4 ), (2 S )-7-hydroxyflavanone ( 5 ), and 2′,4′-dihydroxychalcone ( 6 ). The structures of these compounds were elucidated by a combination analysis of spectroscopic data. The cytotoxic activities of all the isolated compounds against PC-3 human prostate cancer cell line are also presented.
Keywords	Oxytropis chiliophylla ; Oxytropis ; biflavonoids ; Organic chemistry ; QD241-441
Language	English
Publishing date	2019-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Rhamnocitrin glycosides from Oxytropis chiliophylla

Wang, Jun / Hong Liang / Kewu Zeng / Norbo Kelsang / Pengfei Tu / Qingying Zhang / Yang Liu

Phytochemical Society of Europe Phytochemistry letters. 2017 Mar., v. 19

2017

Abstract: Repeated chromatography of the n-BuOH soluble fraction from ethanol extract of the aerial part of Oxytropis chiliophylla led to the isolation of six new rhamnocitrin glycosides, named oxychilioflavonosides A−F (1–6), together with eight known ... ...

Abstract	Repeated chromatography of the n-BuOH soluble fraction from ethanol extract of the aerial part of Oxytropis chiliophylla led to the isolation of six new rhamnocitrin glycosides, named oxychilioflavonosides A−F (1–6), together with eight known rhamnocitrin glycosides (7–14) of which six were isolated from the genus Oxytropis for the first time. The structures of these compounds were elucidated by extensive spectroscopic techniques and chemical methods. All isolated compounds were evaluated for their anti-inflammatory activity in lipopolysaccharide (LPS)-induced BV-2 microglial cells, and compound 11 showed potent inhibition on NO production with IC50 value of 9.91μM.
Keywords	aerial parts ; anti-inflammatory activity ; chromatography ; ethanol ; glycosides ; inhibitory concentration 50 ; lipopolysaccharides ; nitric oxide ; Oxytropis ; spectroscopy
Language	English
Dates of publication	2017-03
Size	p. 50-54.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	1874-3900
DOI	10.1016/j.phytol.2016.11.011
Database	NAL-Catalogue (AGRICOLA)

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Article: Cytotoxic oleanane triterpenoid saponins from Albizia julibrissin

Han, Qinghua / Hong Liang / Jingrong Cui / Pengfei Tu / Qingying Zhang / Xuda Wang / Yi Qian

Fitoterapia. 2017 Sept., v. 121

2017

Abstract: Bioassay-guided fractionation of the ethanolic extract of the stem bark of Albizia julibrissin led to the isolation of ten new oleanane-type triterpenoid saponins, julibrosides J37âJ46 (1â10), along with six known analogues (11â16). In addition, 11 ...

Abstract	Bioassay-guided fractionation of the ethanolic extract of the stem bark of Albizia julibrissin led to the isolation of ten new oleanane-type triterpenoid saponins, julibrosides J37âJ46 (1â10), along with six known analogues (11â16). In addition, 11 prosapogenins (17â27) were prepared by mild or strong alkaline hydrolysis of the total saponin. The structures of 1â27 were determined by spectroscopic and chemical means, and their cytotoxicities against four human cancer cell lines, BGC-823, A549, HCT-116, and HepG2 were evaluated. Compounds 5â16 exhibited significant inhibitory activity with IC50 values ranging from 2.59 to 9.30Î¼M, and 8 turned out to be the most active compound with all IC50 values <5Î¼M. A preliminary structure-activity relationship of these saponins clearly indicated that the outer monoterpenoid moiety (MTâ²) is a crucial substituent for cytotoxicity, and the linkage sites of the MTâ² unit greatly influenced the activity. It could also be inferred that the existence of 16-OH of the aglycone almost has no effect on cytotoxicity and the N-acetyl-glucosamine moiety at C-3 seems to enhance activity.
Keywords	active ingredients ; Albizia julibrissin ; alkaline hydrolysis ; anti-inflammatory activity ; bark ; cytotoxicity ; fractionation ; humans ; hydroxyl radicals ; inhibitory concentration 50 ; medicinal plants ; monoterpenoids ; neoplasms ; spectroscopy ; structure-activity relationships ; triterpenoid saponins
Language	English
Dates of publication	2017-09
Size	p. 183-193.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2017.07.015
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Azukisapogenol Triterpene Glycosides from Oxytropis chiliophylla Royle

Jun Wang / Hongshuai Yang / Yang Liu / Kelsang Norbo / Kewu Zeng / Mingbo Zhao / Hong Liang / Pengfei Tu / Qingying Zhang

Molecules, Vol 23, Iss 10, p

2018 Volume 2448

Abstract: Eight azukisapogenol triterpene glycosides, including five new compounds, oxychiliotriterpenosides A–E (1–5), two new methyl glucuronide derivatives that proved to be artifacts, oxychiliotriterpenoside E-glucuronic acid methyl ester (6) and myrioside B- ... ...

Abstract	Eight azukisapogenol triterpene glycosides, including five new compounds, oxychiliotriterpenosides A–E (1–5), two new methyl glucuronide derivatives that proved to be artifacts, oxychiliotriterpenoside E-glucuronic acid methyl ester (6) and myrioside B-glucuronic acid methyl ester (7), and a known one, myrioside B (8), was isolated from the aerial part of Oxytropis chiliophylla Royle. Their structures were elucidated based on extensive spectroscopic analyses and chemical methods. Triterpene glycosides were first obtained from O. chiliophylla, and those containing a galactose unit (1, 2, 5 and 6) and diglucosidic or triglucosidic linkage at C-29 (1–4), were reported from Oxytropis species for the first time, which might be recognized as a chemotaxonomic feature of O. chiliophylla. All isolated compounds were evaluated for their anti-inflammatory activities against NO production using lipopolysaccharide (LPS)-induced RAW 264.7 cells, but no compounds showed potent inhibition on NO production.
Keywords	Oxytropis ; Oxytropis chiliophylla ; azukisapogenol triterpene glycosides ; anti-inflammatory activity ; Organic chemistry ; QD241-441
Language	English
Publishing date	2018-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Ambient air pollution and markers of fetal growth

Pi Guo / Yuliang Chen / Haisheng Wu / Jing Zeng / Zhisheng Zeng / Weiping Li / Qingying Zhang / Xia Huo / Wenru Feng / Jiumin Lin / Huazhang Miao / Yingxian Zhu

Environment International, Vol 135, Iss , Pp - (2020)

A retrospective population-based cohort study of 2.57 million term singleton births in China

2020

Abstract: Backgrounds: Evidence is scarce on the relation between maternal exposure to ambient air pollution during pregnancy and fetal growth in developing countries. Moreover, the current evidence is inconsistent. We aimed to investigate the association of ... ...

Abstract	Backgrounds: Evidence is scarce on the relation between maternal exposure to ambient air pollution during pregnancy and fetal growth in developing countries. Moreover, the current evidence is inconsistent. We aimed to investigate the association of trimester-specific exposure to air pollution with risk of being born small for gestational age (SGA) and birth weight-markers of fetal growth-among Chinese term births. Methods: This retrospective population-based cohort study consisted of 2,567,457 singleton term live-births from January 1, 2014 to December 31, 2017 across 123 Chinese districts and counties. Personal exposure to ambient air pollutants including carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), particulate matter with aerodynamic diameter < 2.5 μm (PM2.5), and PM10 was assigned using the inverse distance weighting spatial interpolation algorithm. Generalized estimating equations (GEE) logistic regression models were performed to estimate the associations between trimester-specific exposure to air pollution and risk of SGA or low birth weight (LBW), and GEE linear regression to examine the associations between the exposure and term birth weight, adjusting for maternal demographics, maternal cigarette smoking status during pregnancy, mode of delivery, gravidity, gestational age, year and month of conception, neonate’s sex, and meteorological factors. Stratified and sensitivity analyses were also performed. Results: When mother exposed to ambient air pollutants over the entire pregnancy, per IQR increment (0.122 mg/m3) in ambient CO concentrations was associated with higher risk of SGA (odds ratio (OR) = 1.04, 95% confidence interval (CI): 1.02, 1.05) and reduced birth weight among term births (−5.95 g, 95% CI: −8.01, −3.89). This association was also pronounced in the second and third trimesters. Term birth weight was negatively associated with per IQR increase of O3 (−3.52 g, 95% CI: −6.23, −0.81), PM2.5 (−5.93 g, 95% CI: −8.36, −3.49) and PM10 (−7.78 g, 95% CI: −10.41, ...
Keywords	Environmental sciences ; GE1-350
Subject code	333 ; 610
Language	English
Publishing date	2020-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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