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  1. Article: Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: Markers predicting immune-checkpoint inhibitor efficacy and immune-related adverse events.

    Jiang, Qiu-Yu / Xue, Ru-Yi

    World journal of gastrointestinal oncology

    2024  Volume 16, Issue 3, Page(s) 577–582

    Abstract: We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor (ICI) and the occurrence of immune-related adverse events (irAEs). The predictive potential of neutrophil-to-lymphocyte ratio (NLR) ...

    Abstract We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor (ICI) and the occurrence of immune-related adverse events (irAEs). The predictive potential of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in determining ICI effectiveness has been extensively investigated, while limited research has been conducted on predicting irAEs. Furthermore, the combined model incorporating NLR and PLR, either with each other or in conjunction with additional markers such as carcinoembryonic antigen, exhibits superior predictive capabilities compared to individual markers alone. NLR and PLR are promising markers for clinical applications. Forthcoming models ought to incorporate established efficacious models and newly identified ones, thereby constituting a multifactor composite model. Furthermore, efforts should be made to explore effective clinical application approaches that enhance the predictive accuracy and efficiency.
    Language English
    Publishing date 2024-04-03
    Publishing country China
    Document type Editorial
    ZDB-ID 2573696-6
    ISSN 1948-5204
    ISSN 1948-5204
    DOI 10.4251/wjgo.v16.i3.577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Opioids and opioid receptors in pain, addiction, and mood disorders.

    Qiu, Yu / Wang, Yu-Jun

    Frontiers in psychiatry

    2024  Volume 15, Page(s) 1382894

    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2024.1382894
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  3. Article ; Online: Granulomatous Reaction to Inappropriate Filler Used as Hyaluronic Acid in Face.

    Qiu, Yu / Xiang, Wenzhong

    Aesthetic plastic surgery

    2023  

    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Letter
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-023-03758-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1296: Show issues Location:
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  4. Article ; Online: Correlation of the pathological features of benign and malignant thyroid nodules with ultrasonic elastography parameters

    Qiu Yu

    Journal of Hainan Medical University, Vol 24, Iss 16, Pp 85-

    2018  Volume 88

    Abstract: Objective: To investigate the correlation of the pathological features of benign and malignant thyroid nodules with ultrasonic elastography parameters. Methods: A total of 176 patients with thyroid tumor who underwent thyroid tumor resection in this ... ...

    Abstract Objective: To investigate the correlation of the pathological features of benign and malignant thyroid nodules with ultrasonic elastography parameters. Methods: A total of 176 patients with thyroid tumor who underwent thyroid tumor resection in this hospital between September 2016 and February 2018 were chosen as the research subjects, the 119 patients with thyroid cancer were selected as thyroid cancer group and the 57 patients with thyroid adenoma were selected as thyroid adenoma group. The thyroid cancer-related proliferation gene and thyroid cancer-related invasion gene expression as well as ultrasonic strain ratio in tumor tissues were compared between the two groups, and Pearson test was used to evaluate the correlation between above malignant molecule expression and ultrasonic strain ratio. Results: Thyroid cancer-related proliferation genes FOXA1, YAP and TPX2 mRNA expression in lesion tissues of thyroid cancer group were higher than those of thyroid adenoma group whereas EGCG and PDCD4 mRNA expression were lower than those of thyroid adenoma group; thyroid cancer-related invasion genes BRD4, Twist1, FoxM1 and SIRT1 expression were higher than those of thyroid adenoma group whereas Wortmannin and HIC1 mRNA expression were lower than those of thyroid adenoma group; ultrasonic strain ratio was higher than that of thyroid adenoma group. The Pearson test showed that the proliferation gene and invasion gene expression in thyroid cancer tissues were directly correlated with the ultrasonic strain ratio level. Conclusion: Thyroid cancer-related proliferation gene and invasion gene expression are directly correlated with ultrasonic strain ratio level, and ultrasonic elastography can be the reliable means to judge benign and malignant thyroid nodules.
    Keywords Thyroid cancer ; Proliferation activity ; Invasion activity ; Ultrasonic elastography ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2018-08-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Correlation of TI-RADS grading with oncogene and invasion molecule expression in thyroid cancer lesions

    Qiu Yu

    Journal of Hainan Medical University, Vol 24, Iss 15, Pp 69-

    2018  Volume 72

    Abstract: Objective: To explore the correlation of TI-RADS grading with oncogene and invasion molecule expression in thyroid cancer lesions. Methods: Patients who were diagnosed with thyroid cancer in this hospital between January 2017 and January 2018 were ... ...

    Abstract Objective: To explore the correlation of TI-RADS grading with oncogene and invasion molecule expression in thyroid cancer lesions. Methods: Patients who were diagnosed with thyroid cancer in this hospital between January 2017 and January 2018 were divided into TIRADS grade 4 group (n=54) and TI-RADS grade 5 group (n=56) according to TI-RADS grading. 50 patients who underwent surgery and were diagnosed with thyroid adenoma in this hospital during the same period were chosen as benign thyroid group. The differences in the expression of oncogenes and invasion molecules in lesion tissues were compared among the three groups. Results: Proto-oncogenes c-myc, c-erbB-2, RET and TRK mRNA expression in lesions of TI-RADS grade 4 group and TI-RADS grade 5 group were higher than those of benign thyroid group whereas tumor suppressor genes DPC4, p53, PTEN and HBB mRNA expression were lower than those of benign thyroid group; invasion molecules BCORL1, BRD4, STAT3, CD151, SATB1 and CXCR4 mRNA expression were higher than those of benign thyroid group whereas ST7L mRNA expression were lower than that of thyroid benign group. With the increase of TI-RADS grading, the changes in the expression of oncogenes and invasion molecules were aggravated. Conclusion: The changes in oncogene and invasion molecule expression were aggravated with the increase of TI-RADS grading of thyroid cancer, and the specific TI-RADS grading was positively correlated with tumor malignancy.
    Keywords Thyroid cancer ; TI-RADS grading ; Oncogene ; Invasion molecule ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2018-08-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Altered functional connectivity between the default mode network in primary angle-closure glaucoma patients.

    Tang, Qiu-Yu / Huang, Bing-Lin / Huang, Xin

    Neuroreport

    2024  Volume 35, Issue 3, Page(s) 129–135

    Abstract: Previous studies have recognized glaucoma as a neurodegenerative disease that causes extensive brain damage and is closely associated with cognitive function. In this study, we employed functional MRI to examine the intrinsic functional connectivity ... ...

    Abstract Previous studies have recognized glaucoma as a neurodegenerative disease that causes extensive brain damage and is closely associated with cognitive function. In this study, we employed functional MRI to examine the intrinsic functional connectivity patterns of the default mode network (DMN) in patients diagnosed with primary angle-closure glaucoma (PACG), exploring its association with cognitive dysfunction. A total of 34 patients diagnosed with PACG and 34 healthy controls (HC), who were matched in terms of sex, age, and education, were included in the control group. The posterior cingulate cortex (PCC) was selected as the region of interest to examine functional connectivity alterations. Compared with the HC group, functional connectivity was attenuated in left anterior cingulum cortex and left paracentral lobule between with PCC in the PACG group, the results are statistically significant. Our study revealed that patients with PACG exhibit weakened functional connectivity within the DMN. This finding suggests the presence of a neurological mechanism that is associated with both visual dysfunction and cognitive impairments in PACG patients. Furthermore, our study provides neuroimaging evidence that can aid in the exploration of spontaneous neurological alterations and facilitate a deeper investigation of alterations in the visual conduction pathways of PACG patients.
    MeSH term(s) Humans ; Neurodegenerative Diseases ; Glaucoma, Angle-Closure/diagnostic imaging ; Default Mode Network ; Neural Pathways/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Brain ; Brain Mapping
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1049746-8
    ISSN 1473-558X ; 0959-4965
    ISSN (online) 1473-558X
    ISSN 0959-4965
    DOI 10.1097/WNR.0000000000001995
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3118: Show issues Location:
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  7. Article ; Online: Effect of combining intrauterine cerebral blood flow changes with electrical activity on prognostic evaluation of brain injury.

    Yao, Juan / Zhang, Man / Qiu, Yu

    World neurosurgery

    2024  

    Abstract: Objectives: We sought to investigate the value of combining intrauterine cerebral blood flow changes with brain electrical activity examination in evaluating the prognosis of brain injury.: Methods: A total of 90 preterm infants were enrolled and ... ...

    Abstract Objectives: We sought to investigate the value of combining intrauterine cerebral blood flow changes with brain electrical activity examination in evaluating the prognosis of brain injury.
    Methods: A total of 90 preterm infants were enrolled and divided into two groups: the brain damaged preterm infants group (n=55) and the non-brain damaged preterm infants group (n=35).The diagnostic efficacy of combining intrauterine cerebral blood flow changes with EEG activity examination in predicting the prognosis of preterm infants with brain injury was evaluated usingT-test. Pearson linear correlation was applied to analyze the relationship between fetal intrauterine cerebral blood flow changes combined with electrical activity examination and the prognosis of brain injury.
    Results: Significant differences were seen in pulse index, S/D ratio, and other indexes between the two groups (P<0.05). The combined approach of intrauterine cerebral blood flow changes with EEG activity examination demonstrated significantly higher values for area under the curve (AUC), sensitivityand negative predictive value compared to using intrauterine cerebral blood flow changes or EEG activity examination alone (P<0.05). A positive correlation was found between fetal intrauterine cerebral blood flow and electrical activity examination (P<0.05).
    Summary: Combining the assessment of intrauterine cerebral blood flow changes with cerebral electrical activity examination proved beneficial in diagnosing the prognosis of brain injury and provided an important reference for early clinical intervention.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2024.04.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: The complete chloroplast genome of

    Yang, Guan-Song / Qiu, Yu / Yang, Zheng-An

    Mitochondrial DNA. Part B, Resources

    2024  Volume 9, Issue 4, Page(s) 557–562

    Abstract: Keteleeria ... ...

    Abstract Keteleeria evelyniana
    Language English
    Publishing date 2024-04-26
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2024.2345780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Research on Dongguan Mobile Phone Industry Development Status from the Patent Perspective

    Qiu Yu

    Zhishi guanli luntan, Vol 2, Iss 2, Pp 97-

    2017  Volume 109

    Abstract: Purpose/significance] Through the analysis of the patent of five Dongguan mobile phone industries, this paper aims at providing information references for the development of Dongguan mobile phone industry. [Method/process] This paper first introduced ... ...

    Abstract [Purpose/significance] Through the analysis of the patent of five Dongguan mobile phone industries, this paper aims at providing information references for the development of Dongguan mobile phone industry. [Method/process] This paper first introduced the basic information of the mobile phone industry in our country, selected Dongguan mobile phone industry patents as the research object, and analyzed overall development trend--the general situation and the trend of applicants, inventors and IPC classification, and the applicant form of IPC classification and IPC classification technical correlation. Finally, it pointed out the open questions, and put forward suggestions. [Result/conclusion] Based on the above analysis, this paper puts forward the following five suggestions for the development of Dongguan mobile phone industry: first, reinforcing the patent situation analysis of the mobile phone industry; second, establishing the mobile phone industry thematic database; third, enhancing the ability of enterprise technology research and development; fourth, supporting key enterprises; fifth, improving the mobile phone industry chain.
    Keywords mobile phone industry ; Dongguan ; patent ; intelligence analysiscitation analysis ; Bibliography. Library science. Information resources ; Z
    Subject code 380
    Language Chinese
    Publishing date 2017-03-01T00:00:00Z
    Publisher LIS Press
    Document type Article ; Online
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  10. Article: Formulation and Interpretation of International Diagnostic Guidelines for Blood-Stasis Syndrome.

    Qiu, Yu / Xu, Hao

    Chinese journal of integrative medicine

    2022  Volume 28, Issue 4, Page(s) 291–296

    MeSH term(s) Diagnosis, Differential ; Medicine, Chinese Traditional
    Language English
    Publishing date 2022-03-31
    Publishing country China
    Document type Editorial
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-022-2889-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5823: Show issues Location:
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