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  1. AU="Qu, C"
  2. AU="Flett, Heather"
  3. AU="Shueh Lin Lim"
  4. AU="Schröder, Johann"
  5. AU=Butler Taylor
  6. AU="Yang, Fan"
  7. AU="Giacomo Frati"
  8. AU=Kokhaei P
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  10. AU="Salil Bhargava"
  11. AU="Jong-Eun Lee"
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  1. Buch ; Online: Facial Texture Super-Resolution by Fitting 3D Face Models

    Qu, Chengchao

    2018  

    Abstract: This book proposes to solve the low-resolution (LR) facial analysis problem with 3D face super-resolution (FSR). A complete processing chain is presented towards effective 3D FSR in real world. To deal with the extreme challenges of incorporating 3D ... ...

    Abstract This book proposes to solve the low-resolution (LR) facial analysis problem with 3D face super-resolution (FSR). A complete processing chain is presented towards effective 3D FSR in real world. To deal with the extreme challenges of incorporating 3D modeling under the ill-posed LR condition, a novel workflow coupling automatic localization of 2D facial feature points and 3D shape reconstruction is developed, leading to a robust pipeline for pose-invariant hallucination of the 3D facial texture
    Schlagwörter Electronic computers. Computer science
    Umfang 1 electronic resource (ix, 205 p. p.)
    Verlag KIT Scientific Publishing
    Erscheinungsort Verlagsort nicht ermittelbar
    Dokumenttyp Buch ; Online
    Anmerkung ENGLISH ; Open Access
    HBZ-ID HT020196286
    ISBN 9783731508281 ; 3731508281
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Artikel: Editorial: The tumor microenvironment and malignant properties in primary liver cancer.

    Qu, Chen

    Frontiers in oncology

    2023  Band 13, Seite(n) 1264439

    Sprache Englisch
    Erscheinungsdatum 2023-08-21
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1264439
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: The correlated influence of semantic types, L1 translation equivalents and language proficiency on EFL learners' production of polysemous words.

    Qu, Chunhong

    Frontiers in psychology

    2023  Band 14, Seite(n) 1162008

    Abstract: The current research investigated the influencing factors of the full mastery of L2 (English) polysemous words with a Chinese-English translation test. The concepts of "meaning" and "L2 equivalent" were strictly distinguished when designing the test. The ...

    Abstract The current research investigated the influencing factors of the full mastery of L2 (English) polysemous words with a Chinese-English translation test. The concepts of "meaning" and "L2 equivalent" were strictly distinguished when designing the test. The manipulation of variables came to a mixed design of 2 (semantic types: core meaning, periphery meaning) × 2 (types of L1 translation equivalents: dominant L1 translation equivalent, non-dominant L1 translation equivalent) × 2 (language proficiency: low proficiency, high proficiency). The results showed that: (1) The semantic types and L1 translation equivalents had significant influence on the production of polysemous words in that the core meanings and the dominant L1 translation equivalent helped the learners access the words quickly and produce them more efficiently; The dominant L1 translation equivalents could facilitate the production of the words presented with their periphery meanings; (2) On the whole, there was no significant difference of the productive competence between the two groups of participants. Comparatively, the high proficiency learners performed better in the production of words presented in their periphery meanings corresponding to non-dominant L1 translation equivalents. And they showed a less degree of dependence on L1 translation equivalents in the process of language production.
    Sprache Englisch
    Erscheinungsdatum 2023-12-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1162008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Regulation of Oxygen Tension as a Strategy to Control Chondrocytic Phenotype for Cartilage Tissue Engineering and Regeneration.

    Lammi, Mikko J / Qu, Chengjuan

    Bioengineering (Basel, Switzerland)

    2024  Band 11, Heft 3

    Abstract: Cartilage defects and osteoarthritis are health problems which are major burdens on health care systems globally, especially in aging populations. Cartilage is a vulnerable tissue, which generally faces a progressive degenerative process when injured. ... ...

    Abstract Cartilage defects and osteoarthritis are health problems which are major burdens on health care systems globally, especially in aging populations. Cartilage is a vulnerable tissue, which generally faces a progressive degenerative process when injured. This makes it the 11th most common cause of global disability. Conservative methods are used to treat the initial phases of the illness, while orthopedic management is the method used for more progressed phases. These include, for instance, arthroscopic shaving, microfracturing and mosaicplasty, and joint replacement as the final treatment. Cell-based implantation methods have also been developed. Despite reports of successful treatments, they often suffer from the non-optimal nature of chondrocyte phenotype in the repair tissue. Thus, improved strategies to control the phenotype of the regenerating cells are needed. Avascular tissue cartilage relies on diffusion for nutrients acquisition and the removal of metabolic waste products. A low oxygen content is also present in cartilage, and the chondrocytes are, in fact, well adapted to it. Therefore, this raises an idea that the regulation of oxygen tension could be a strategy to control the chondrocyte phenotype expression, important in cartilage tissue for regenerative purposes. This narrative review discusses the aspects related to oxygen tension in the metabolism and regulation of articular and growth plate chondrocytes and progenitor cell phenotypes, and the role of some microenvironmental factors as regulators of chondrocytes.
    Sprache Englisch
    Erscheinungsdatum 2024-02-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering11030211
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: [Predictive value of low-density lipoprotein cholesterol/remnant cholesterol coordination on cardiovascular and cerebrovascular events in elderly patients with hypertension].

    Qu, C / Qi, S Y / Li, X / Gao, H

    Zhonghua xin xue guan bing za zhi

    2023  Band 51, Heft 8, Seite(n) 844–850

    Abstract: Objective: ...

    Abstract Objective:
    Mesh-Begriff(e) Male ; Humans ; Aged ; Middle Aged ; Aged, 80 and over ; Cholesterol, LDL ; Prospective Studies ; Cholesterol ; Heart Failure ; Risk Factors ; Hypertension ; Stroke
    Chemische Substanzen Cholesterol, LDL ; Cholesterol (97C5T2UQ7J)
    Sprache Chinesisch
    Erscheinungsdatum 2023-08-16
    Erscheinungsland China
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20230107-00017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: MicroRNA Sensors Based on CRISPR/Cas12a Technologies: Evolution From Indirect to Direct Detection.

    Yu, Songcheng / Lei, Xueying / Qu, Chenling

    Critical reviews in analytical chemistry

    2024  , Seite(n) 1–17

    Abstract: MicroRNA (miRNA) has emerged as a promising biomarker for disease diagnosis and a potential therapeutic targets for drug development. The detection of miRNA can serve as a noninvasive tool in diseases diagnosis and predicting diseases prognosis. CRISPR/ ... ...

    Abstract MicroRNA (miRNA) has emerged as a promising biomarker for disease diagnosis and a potential therapeutic targets for drug development. The detection of miRNA can serve as a noninvasive tool in diseases diagnosis and predicting diseases prognosis. CRISPR/Cas12a system has great potential in nucleic acid detection due to its high sensitivity and specificity, which has been developed to be a versatile tool for nucleic acid-based detection of targets in various fields. However, conversion from RNA to DNA with or without amplification operation is necessary for miRNA detection based on CRISPR/Cas12a system, because dsDNA containing PAM sequence or ssDNA is traditionally considered as the activator of Cas12a. Until recently, direct detection of miRNA by CRISPR/Cas12a system has been reported. In this review, we provide an overview of the evolution of biosensors based on CRISPR/Cas12a for miRNA detection from indirect to direct, which would be beneficial to the development of CRISPR/Cas12a-based sensors with better performance for direct detection of miRNA.
    Sprache Englisch
    Erscheinungsdatum 2024-03-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2030019-0
    ISSN 1547-6510 ; 1040-8347
    ISSN (online) 1547-6510
    ISSN 1040-8347
    DOI 10.1080/10408347.2024.2329229
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Effects of accommodation on geometrical parameters of human lens: A systematic review and meta-analysis.

    Zhang, Guanghong / Jiang, Jun / Wei, Qian / Qu, Chao

    Heliyon

    2024  Band 10, Heft 8, Seite(n) e29298

    Abstract: Purpose: To investigate the effects of accommodation on the geometrical parameters of human lens.: Methods: Eight databases from inception to November 2023 were used for the literature search: CNKI, CBM, VIP, Wan-Fang, PubMed, Web of Science, EMBASE, ...

    Abstract Purpose: To investigate the effects of accommodation on the geometrical parameters of human lens.
    Methods: Eight databases from inception to November 2023 were used for the literature search: CNKI, CBM, VIP, Wan-Fang, PubMed, Web of Science, EMBASE, and the Cochrane Library. The Methodological Index for Non-randomized Studies was used to assess the risk of bias. The PRISMA were followed and the following outcomes were taken into consideration: lens diameter (LD), lens thickness (LT), anterior curvature radius (ACR), posterior curvature radius (PCR), lens center position (LCP), and total cross-sectional area (TCSA). This systematic review was registered on an international platform for registered systematic reviews and meta-analysis (INPLASY202260085).
    Results: A total of 19 studies were included. LT increased by 0.04 mm/D (18 studies; 95% confidence interval [CI], 0.03-0.06;
    Conclusions: Changes in LT, LD, ACR, PCR and LCP supported Helmholtz's theory. Different apparatuses or measurement methods influenced the measurement of lens geometrical parameters.
    Sprache Englisch
    Erscheinungsdatum 2024-04-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29298
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Recent Progress on Conversion of Lignocellulosic Biomass by MOF-Immobilized Enzyme.

    Tao, Juan / Song, Shengjie / Qu, Chen

    Polymers

    2024  Band 16, Heft 7

    Abstract: The enzyme catalysis conversion of lignocellulosic biomass into valuable chemicals and fuels showed a bright outlook for replacing fossil resources. However, the high cost and easy deactivation of free enzymes restrict the conversion process. ... ...

    Abstract The enzyme catalysis conversion of lignocellulosic biomass into valuable chemicals and fuels showed a bright outlook for replacing fossil resources. However, the high cost and easy deactivation of free enzymes restrict the conversion process. Immobilization of enzymes in metal-organic frameworks (MOFs) is one of the most promising strategies due to MOF materials' tunable building units, multiple pore structures, and excellent biocompatibility. Also, MOFs are ideal support materials and could enhance the stability and reusability of enzymes. In this paper, recent progress on the conversion of cellulose, hemicellulose, and lignin by MOF-immobilized enzymes is extensively reviewed. This paper focuses on the immobilized enzyme performances and enzymatic mechanism. Finally, the challenges of the conversion of lignocellulosic biomass by MOF-immobilized enzyme are discussed.
    Sprache Englisch
    Erscheinungsdatum 2024-04-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16071010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Frequency-Aware Degradation Modeling for Real-World Thermal Image Super-Resolution.

    Qu, Chao / Chen, Xiaoyu / Xu, Qihan / Han, Jing

    Entropy (Basel, Switzerland)

    2024  Band 26, Heft 3

    Abstract: The supervised super-resolution (SR) methods based on simple degradation assumptions (e.g., bicubic downsampling) have unsatisfactory generalization ability on real-world thermal images. To enhance the SR effect of real-world sceneries, we introduce an ... ...

    Abstract The supervised super-resolution (SR) methods based on simple degradation assumptions (e.g., bicubic downsampling) have unsatisfactory generalization ability on real-world thermal images. To enhance the SR effect of real-world sceneries, we introduce an unsupervised SR framework for thermal images, incorporating degradation modeling and corresponding SR. Inspired by the physical prior that high frequency affects details and low frequency affects thermal contrast, we propose a frequency-aware degradation model, named TFADGAN. The model achieves image quality migration between thermal detectors of different resolutions by degrading different frequency components of the image from high-resolution (HR) to low-resolution (LR). Specifically, by adversarial learning with unpaired LR thermal images, the complex degradation processes of HR thermal images at low and high frequencies are modeled separately. Benefiting from the thermal characteristics mined from real-world images, the degraded images generated by TFADGAN are similar to LR thermal ones in terms of detail and contrast. Then, the SR model is trained based on the pseudo-paired data consisting of degraded images and HR images. Extensive experimental results demonstrate that the degraded images generated by TFADGAN provide reliable alternatives to real-world LR thermal images. In real-world thermal image experiments, the proposed SR framework can improve the peak signal-to-noise ratio (PSNR) and structural similarity degree (SSIM) by 1.28 dB and 0.02, respectively.
    Sprache Englisch
    Erscheinungsdatum 2024-02-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e26030209
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Prognostic value and potential mechanism of cellular senescence and tumor microenvironment in hepatocellular carcinoma: Insights from bulk transcriptomics and single-cell sequencing analysis.

    Qu, Chang / Wu, Qian / Lu, Jiongdi / Li, Fei

    Environmental toxicology

    2024  Band 39, Heft 5, Seite(n) 2512–2527

    Abstract: The high mortality rate and postoperative recurrence of hepatocellular carcinoma (HCC) contribute to the burden on society and healthcare. The prognostic value and underlying mechanisms of cellular senescence and tumor microenvironment (TME) in HCC ... ...

    Abstract The high mortality rate and postoperative recurrence of hepatocellular carcinoma (HCC) contribute to the burden on society and healthcare. The prognostic value and underlying mechanisms of cellular senescence and tumor microenvironment (TME) in HCC remain unclear. Bulk transcriptomic data were obtained from 368 HCC samples in The Cancer Genome Atlas-liver hepatocellular carcinoma cohort and 64 samples from the GSE116174 dataset. Single-cell RNA sequencing (scRNA-seq) data of HCC were obtained from the GSE149614 dataset, including 18 tumor samples from 10 patients. Prognosis-related cellular senescence genes and immune cells were identified through univariate analysis. Least absolute shrinkage and selection operator regression analysis was performed to construct the CellAge score and TME score, both of which were identified as independent prognostic factors for HCC based on multivariate Cox analysis. The combined CellAge and TME scores showed improved prognostic stratification for HCC patients, as confirmed by multivariate Cox analysis (p < .001). The gene set enrichment analysis (GSEA) revealed enrichment of the extracellular matrix receptor interaction signaling pathway in the group with high CellAge scores and low TME scores, which exhibited a worse prognosis. Single-cell sequencing results revealed higher expression activity of the cAMP response element modulator (CREM) extended transcription factor in HCC cells and most immune cells, indicating its involvement in TME remodeling. Finally, the tumor immune dysfunction and exclusion (TIDE) analysis demonstrated that the combined scores could predict the outcomes of immune therapy in patients with HCC. In conclusion, cellular senescence contributes to TME remodeling in HCC, and the developed CellAge and TME scores serve as independent prognostic factors and predictors of immune therapy in HCC.
    Mesh-Begriff(e) Humans ; Carcinoma, Hepatocellular/genetics ; Prognosis ; Liver Neoplasms/genetics ; Tumor Microenvironment/genetics ; Cellular Senescence/genetics ; Gene Expression Profiling
    Sprache Englisch
    Erscheinungsdatum 2024-01-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1463449-1
    ISSN 1522-7278 ; 1520-4081
    ISSN (online) 1522-7278
    ISSN 1520-4081
    DOI 10.1002/tox.24121
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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