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  1. Book ; Online: Activation and Suppression of Plant Immunity

    Fu, Zhengqing / Qu, Feng / Wang, Shui / Li, Yi / Mitchell, Thomas

    2020  

    Keywords Science: general issues ; Botany & plant sciences ; MAMP-triggered immunity ; effector-triggered immunity ; salicyclic acid ; reactive oxgen species
    Size 1 electronic resource (326 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230156
    ISBN 9782889632930 ; 2889632938
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Examining the joint coordination during dynamic balance learning using vector coding and statistical parametric mapping analyses.

    Kim, Sungmin / Qu, Feng / Wang, Yi / Lam, Wing-Kai

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1724

    Abstract: We aimed to examine the changes in balance performance, kinematic variables, and joint coordination of the lower extremities during the Y-balance learning task. Twenty female university students completed five consecutive blocks of Y-balance learning ... ...

    Abstract We aimed to examine the changes in balance performance, kinematic variables, and joint coordination of the lower extremities during the Y-balance learning task. Twenty female university students completed five consecutive blocks of Y-balance learning from days 3 to 7 (135 trials). Pre-tests and tests were performed on days 1 and 9. Maximum reach distance, peak joint angle, and joint coordination in the anterior (AL), posterolateral (PL), and posteromedial (PM) directions were measured to determine the efficacy of Y-balance performance. A repeated measures ANOVA was performed for the maximum reach distance across learning blocks to confirm whether learning had occurred. Our results indicated that the maximum reach distance on day 5 was longer than that on other learning days. The maximum reach distance significantly increased in the PL and PM directions after learning. The hip flexion (PL/PM), abduction (PM), internal rotation (PM), and external rotation (PL) angles increased after learning. The knee joint flexion angle increased in both AL and PL directions. Only the ankle dorsiflexion angle increased in the AL direction. Joint coordination indicated that the knee and hip joints performed simultaneously during internal rotation. Ankle-knee joint coordination was performed using dorsiflexion and flexion strategies. Statistical parametric mapping analysis indicated significant differences in the ankle sagittal plane in the AL direction, hip horizontal and hip/knee sagittal planes in the PL direction, and hip/knee sagittal and hip frontal/horizontal planes in the PM direction. These data suggest that the dynamic balance ability of the novice participants improved in relation to changes in coordination patterns after learning. The results of this study can be applied to other populations to improve their dynamic balance and prevent fall injuries.
    MeSH term(s) Humans ; Female ; Lower Extremity ; Knee Joint ; Movement ; Ankle Joint ; Range of Motion, Articular ; Biomechanical Phenomena ; Hip Joint
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44216-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Transformer-based 2D/3D medical image registration for X-ray to CT via anatomical features.

    Qu, Feng / Zhang, Min / Shi, Weili / He, Wei / Jiang, Zhengang

    The international journal of medical robotics + computer assisted surgery : MRCAS

    2024  Volume 20, Issue 1, Page(s) e2619

    Abstract: Background: 2D/3D medical image registration is one of the key technologies for surgical navigation systems to perform pose estimation and achieve accurate positioning, which still remains challenging. The purpose of this study is to introduce a new ... ...

    Abstract Background: 2D/3D medical image registration is one of the key technologies for surgical navigation systems to perform pose estimation and achieve accurate positioning, which still remains challenging. The purpose of this study is to introduce a new method for X-ray to CT 2D/3D registration and conduct a feasibility study.
    Methods: In this study, a 2D/3D affine registration method based on feature point detection is investigated. It combines the morphological and edge features of spinal images to accurately extract feature points from the images, and uses graph neural networks to aggregate anatomical features of different points to increase the local detail information. Meanwhile, global and positional information are extracted by the Swin Transformer.
    Results: The results indicate that the proposed method has shown improvements in both accuracy and success ratio compared with other methods. The mean target registration error value reached up to 0.31 mm; meanwhile, the runtime overhead was much lower, achieving an average runtime of about 0.6 s. This ultimately improves the registration accuracy and efficiency, demonstrating the effectiveness of the proposed method.
    Conclusions: The proposed method can provide more comprehensive image information and shows good prospects for pose estimation and achieving accurate positioning in surgical navigation systems.
    MeSH term(s) Humans ; X-Rays ; Algorithms ; Radiography ; Imaging, Three-Dimensional/methods ; Tomography, X-Ray Computed/methods ; Image Processing, Computer-Assisted/methods
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151860-9
    ISSN 1478-596X ; 1478-5951
    ISSN (online) 1478-596X
    ISSN 1478-5951
    DOI 10.1002/rcs.2619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6382: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Aptamer inhibitor selection of SpyCas9 through CE-SELEX.

    Yang, Ge / Wang, Huimin / Jiang, Guangyu / Zhao, Liping / Qu, Feng

    Talanta

    2024  Volume 273, Page(s) 125837

    Abstract: CRISPR/Cas9 is a natural immune system of archaea and bacteria, which has been widely used in gene editing. In order to better control and improve the accuracy and safety of the system, inhibitors for SpyCas9 as "switches" have been selected for several ... ...

    Abstract CRISPR/Cas9 is a natural immune system of archaea and bacteria, which has been widely used in gene editing. In order to better control and improve the accuracy and safety of the system, inhibitors for SpyCas9 as "switches" have been selected for several years. The available inhibitors currently are all natural polypeptides inhibitors derived from phages, except one small molecule inhibitor. These natural inhibitors are challenging to obtain and are available in limited quantities, and the small molecule inhibitor is cytotoxic. Herein, we discover aptamers against the SpyCas9 protein, by coupling CE-SELEX within one-round pressure controllable selection strategy. One of the identified aptamers, Apt2, shows high affinity at the nanomolar level and leads for effective SpyCas9 enzymatic inhibition in vitro. It is predicted that Apt2 interacts with the HNH and RuvC domains of SpyCas9, competitively inhibiting the binding of substrate DNA to SpyCas9. The proposed aptamer inhibitor is the oligonucleotide inhibitor of SpyCas9, which has the potential in construction of the universal, simple and precise CRISPR-Cas9 system activity control strategy. Meanwhile, these aptamers could also be valuable tools for study of the functions of CRISPR/Cas9 and the related functional mechanisms.
    MeSH term(s) Gene Editing ; DNA/chemistry ; Bacterial Proteins/metabolism ; Aptamers, Nucleotide/metabolism ; Bacteriophages ; SELEX Aptamer Technique
    Chemical Substances DNA (9007-49-2) ; Bacterial Proteins ; Aptamers, Nucleotide
    Language English
    Publishing date 2024-03-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2024.125837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Quasispecies are constantly selected through virus-encoded intracellular reproductive population bottlenecking.

    Qu, Feng / Khemsom, Khwannarin / Perdoncini Carvalho, Camila / Han, Junping

    Journal of virology

    2024  Volume 98, Issue 4, Page(s) e0002024

    MeSH term(s) Quasispecies ; Viruses ; Genetic Variation ; Mutation ; Evolution, Molecular
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Letter
    ZDB-ID 80174-4
    ISSN 1098-5514 ; 0022-538X
    ISSN (online) 1098-5514
    ISSN 0022-538X
    DOI 10.1128/jvi.00020-24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 609: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The Effects of Hand Tremors on the Shooting Performance of Air Pistol Shooters with Different Skill Levels.

    Liu, Yu / Hu, Nijia / Sun, Mengzi / Qu, Feng / Zhou, Xinglong

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 8

    Abstract: Physiologic hand tremors are a critical factor affecting the aim of air pistol shooters. However, the extent of the effect of hand tremors on shooting performance is unclear. In this study, we aim to explore the relationship between hand tremors and ... ...

    Abstract Physiologic hand tremors are a critical factor affecting the aim of air pistol shooters. However, the extent of the effect of hand tremors on shooting performance is unclear. In this study, we aim to explore the relationship between hand tremors and shooting performance scores as well as investigate potential links between muscle activation and hand tremors. In this study, 17 male air pistol shooters from China's national team and the Air Pistol Sports Center were divided into two groups: the elite group and the sub-elite group. Each participant completed 40 shots during the experiment, with shooters' hand tremors recorded using three-axis digital accelerometers affixed to their right hands. Muscle activation was recorded using surface electromyography on the right anterior deltoid, posterior deltoid, biceps brachii (short head), triceps brachii (long head), flexor carpi radialis, and extensor carpi radialis. Our analysis revealed weak correlations between shooting scores and hand tremor amplitude in multiple directions (middle-lateral, ML: r
    MeSH term(s) Humans ; Tremor/physiopathology ; Male ; Electromyography ; Hand/physiology ; Hand/physiopathology ; Adult ; Firearms ; Young Adult ; Athletic Performance/physiology ; Muscle, Skeletal/physiopathology ; Muscle, Skeletal/physiology
    Language English
    Publishing date 2024-04-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24082438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: P3 and NIa-Pro of Turnip Mosaic Virus Are Independent Elicitors of Superinfection Exclusion.

    Nunna, Haritha / Qu, Feng / Tatineni, Satyanarayana

    Viruses

    2023  Volume 15, Issue 7

    Abstract: Superinfection exclusion (SIE) is an antagonistic interaction between identical or closely related viruses in host cells. Previous studies by us and others led to the hypothesis that SIE was elicited by one or more proteins encoded in the genomes of ... ...

    Abstract Superinfection exclusion (SIE) is an antagonistic interaction between identical or closely related viruses in host cells. Previous studies by us and others led to the hypothesis that SIE was elicited by one or more proteins encoded in the genomes of primary viruses. Here, we tested this hypothesis using Turnip mosaic virus (TuMV), a member of the genus
    MeSH term(s) Superinfection ; Potyvirus/genetics ; Potyviridae ; Plant Diseases ; Nicotiana
    Language English
    Publishing date 2023-06-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15071459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Advances of aptamer-based small-molecules sensors in body fluids detection.

    Chen, Li / Yang, Ge / Qu, Feng

    Talanta

    2023  Volume 268, Issue Pt 1, Page(s) 125348

    Abstract: The field of aptamer-based sensing has evolved considerably over the past three decades. The aptamer sensor-based detection of small-molecule targets in body fluids is designed for real-time or rapid, low-cost, non- or minimally invasive tracking and ... ...

    Abstract The field of aptamer-based sensing has evolved considerably over the past three decades. The aptamer sensor-based detection of small-molecule targets in body fluids is designed for real-time or rapid, low-cost, non- or minimally invasive tracking and diagnosis of human health status. It can be achieved by specifically monitoring biomarkers or metabolites excreted from various body fluids, including blood, urine, cerebrospinal fluid, saliva, ect. This article reviews a comprehensive collection of aptamer-based sensors for detecting small-molecule in various body fluids. A comparative analysis of aptamer features, emerging chemistry, advanced sensing materials, transduction techniques, and detection performance is conducted, and the strengths and pitfalls of each approach are discussed. Finally, the development process and application challenges of aptamer-based sensors in the detection of small-molecule in body fluids are presented and discussed.
    MeSH term(s) Humans ; Biosensing Techniques/methods ; Body Fluids/chemistry ; Saliva/chemistry ; Aptamers, Nucleotide/chemistry ; Biomarkers/analysis
    Chemical Substances Aptamers, Nucleotide ; Biomarkers
    Language English
    Publishing date 2023-10-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.125348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: P3 and NIa-Pro of Turnip Mosaic Virus Are Independent Elicitors of Superinfection Exclusion

    Nunna, Haritha / Qu, Feng / Tatineni, Satyanarayana

    Viruses. 2023 June 28, v. 15, no. 7 p.1459-

    2023  

    Abstract: Superinfection exclusion (SIE) is an antagonistic interaction between identical or closely related viruses in host cells. Previous studies by us and others led to the hypothesis that SIE was elicited by one or more proteins encoded in the genomes of ... ...

    Abstract Superinfection exclusion (SIE) is an antagonistic interaction between identical or closely related viruses in host cells. Previous studies by us and others led to the hypothesis that SIE was elicited by one or more proteins encoded in the genomes of primary viruses. Here, we tested this hypothesis using Turnip mosaic virus (TuMV), a member of the genus Potyvirus of the family Potyviridae, with significant economic consequences. To this end, individual TuMV-encoded proteins were transiently expressed in the cells of Nicotiana benthamiana leaves, followed by challenging them with a modified TuMV expressing the green fluorescent protein (TuMV-GFP). Three days after TuMV-GFP delivery, these cells were examined for the replication-dependent expression of GFP. Cells expressing TuMV P1, HC-Pro, 6K1, CI, 6K2, NIa-VPg, NIb, or CP proteins permitted an efficient expression of GFP, suggesting that these proteins failed to block the replication of a superinfecting TuMV-GFP. By contrast, N. benthamiana cells expressing TuMV P3 or NIa-Pro did not express visible GFP fluorescence, suggesting that both of them could elicit potent SIE against TuMV-GFP. The SIE elicitor activity of P3 and NIa-Pro was further confirmed by their heterologous expression from a different potyvirus, potato virus A (PVA). Plants systemicall
    Keywords Nicotiana benthamiana ; Potato virus A ; Turnip mosaic virus ; elicitors ; fluorescence ; genome ; green fluorescent protein ; heterologous gene expression ; superinfection
    Language English
    Dates of publication 2023-0628
    Publishing place MDPI AG
    Document type Article ; Online
    Note Resource is Open Access
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15071459
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Effect of high-level PM

    Liu, Yanyu / Li, Daojuan / Ren, Meng / Qu, Feng / He, Yutong

    Environmental science and pollution research international

    2023  Volume 30, Issue 34, Page(s) 82094–82106

    Abstract: Globally, air pollution is the fourth leading risk factor for death, while lung cancer (LC) is the leading cause of cancer-related death. The aim of this study was to explore the prognostic factors of LC and the influence of high fine particulate matter ( ...

    Abstract Globally, air pollution is the fourth leading risk factor for death, while lung cancer (LC) is the leading cause of cancer-related death. The aim of this study was to explore the prognostic factors of LC and the influence of high fine particulate matter (PM
    MeSH term(s) Humans ; Aged ; Air Pollutants/analysis ; Particulate Matter/analysis ; Air Pollution/analysis ; Lung Neoplasms/chemically induced ; China/epidemiology ; Cohort Studies ; Environmental Exposure/adverse effects
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2023-06-15
    Publishing country Germany
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28147-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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