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  1. Article: Multi-source domain adaptation of social media data for disaster management.

    Khattar, Anuradha / Quadri, S M K

    Multimedia tools and applications

    2022  Volume 82, Issue 6, Page(s) 9083–9111

    Abstract: Labeled data scarcity at the time of an ongoing disaster has encouraged the researchers to use the labeled data from some previous disaster for training and transferring the knowledge to the current disaster task using Domain Adaptation (DA). However, ... ...

    Abstract Labeled data scarcity at the time of an ongoing disaster has encouraged the researchers to use the labeled data from some previous disaster for training and transferring the knowledge to the current disaster task using Domain Adaptation (DA). However, often labeled data from more than one previous disaster may be available. As all deep learning models are data-hungry and perform better if fed with more annotated data, it is advisable to use data from multiple sources for training a Deep Convolutional Neural Network (DCNN). One of the easiest ways is to simply combine the data from multiple sources and use it for training. However, this arrangement is not that straightforward. The models trained on the combined data from various sources do not perform well on the target, mainly due to distribution discrepancies between multiple sources. This has motivated us to explore the challenging area of multi-source domain adaptation for disaster management. The aim is to learn the domain invariant features and representations across the domains and transfer more related knowledge to solve the target task with improved accuracy than single-source or combined-source domain adaptation. This study proposes a Multi-Source Domain Adaptation framework for Disaster Management (MSDA-DM) to classify disaster images posted on social media based on unsupervised DA with adversarial training. The empirical results obtained confirm that the proposed model MSDA-DM performs better than single-source DA by up to 10.83% and combined-source DA by up to 5.06% in terms of F1-score for different sets of source and target disaster domains. We also compare our model with current state-of-the-art models. The main challenge of multi-source DA is the choice of the relevant sources taken for training since, unlike single-source DA that handles only source-target distribution drift, the multi-source DA network has to address both source-target and source-source distribution drifts.
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479928-5
    ISSN 1573-7721 ; 1380-7501
    ISSN (online) 1573-7721
    ISSN 1380-7501
    DOI 10.1007/s11042-022-13456-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: scJVAE: A novel method for integrative analysis of multimodal single-cell data.

    Wani, Shahid Ahmad / Khan, Sumeer Ahmad / Quadri, S M K

    Computers in biology and medicine

    2023  Volume 158, Page(s) 106865

    Abstract: The study of cellular decision-making can be approached comprehensively using multimodal single-cell omics technology. Recent advances in multimodal single-cell technology have enabled simultaneous profiling of more than one modality from the same cell, ... ...

    Abstract The study of cellular decision-making can be approached comprehensively using multimodal single-cell omics technology. Recent advances in multimodal single-cell technology have enabled simultaneous profiling of more than one modality from the same cell, providing more significant insights into cell characteristics. However, learning the joint representation of multimodal single-cell data is challenging due to batch effects. Here we present a novel method, scJVAE (single-cell Joint Variational AutoEncoder), for batch effect removal and joint representation of multimodal single-cell data. The scJVAE integrates and learns joint embedding of paired scRNA-seq and scATAC-seq data modalities. We evaluate and demonstrate the ability of scJVAE to remove batch effects using various datasets with paired gene expression and open chromatin. We also consider scJVAE for downstream analysis, such as lower dimensional representation, cell-type clustering, and time and memory requirement. We find scJVAE a robust and scalable method outperforming existing state-of-the-art batch effect removal and integration methods.
    MeSH term(s) Cluster Analysis ; Learning ; Sequence Analysis, RNA ; Gene Expression Profiling ; Single-Cell Analysis
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2023.106865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Thematic Analysis of Online Uveitis Support Groups.

    Rasheed, Haroon Adam / Rasheed, Yusuf Salman / Syed-Quadri, Shafee / Tsui, Edmund

    Ocular immunology and inflammation

    2023  , Page(s) 1–6

    Abstract: Purpose: To report the availability and activity of online uveitis support groups.: Methods: An online search was conducted for support groups for uveitis. Member count and activity were recorded. Posts and comments were graded along five themes: ... ...

    Abstract Purpose: To report the availability and activity of online uveitis support groups.
    Methods: An online search was conducted for support groups for uveitis. Member count and activity were recorded. Posts and comments were graded along five themes: emotional or personal story sharing, information seeking, offer of outside information, emotional support, and expressions of gratitude.
    Results: An online search resulted in 32 support groups for uveitis. Across all groups, there was a median membership of 725 (IQR 1410.5). Of the 32 groups, five were active and accessible at the time of study. In these five groups, 337 posts and 1406 comments were made within the past year. The most prevalent theme in posts consisted of information seeking (84%) while the most prevalent theme in comments consisted of emotion or personal story sharing (65%).
    Conclusions: Online uveitis support groups provide a unique space for emotional support, information sharing, and community building.
    Language English
    Publishing date 2023-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2178937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Why Are Patients With COVID-19 at Risk for Drug-Drug Interactions?

    Preskorn, Sheldon H / Quadri, Syeda

    Journal of psychiatric practice

    2020  Volume 26, Issue 6, Page(s) 485–492

    Abstract: The goal of this column is to provide information to health care professionals about drug-drug interactions (DDIs) and why DDIs are important to consider in those at serious risk of illness with Coronavirus Disease 2019 (COVID-19). Important ... ...

    Abstract The goal of this column is to provide information to health care professionals about drug-drug interactions (DDIs) and why DDIs are important to consider in those at serious risk of illness with Coronavirus Disease 2019 (COVID-19). Important considerations discussed in this column include the frequency and complexity of multiple medication use, particularly important for the older patient who often has multiple comorbid illnesses. The column covers the following issues: (1) Why patients at high risk for serious illness from COVID-19 are also at high risk for DDIs. (2) Application of results of pharmacoepidemiological studies to the population at risk for serious COVID-19 illness. (3) Mechanisms underlying DDIs, frequency and potential complexity of DDIs, and how DDIs can present clinically. (4) Methods for preventing or mitigating DDIs. (5) An introduction to the University of Liverpool drug interaction checker as a tool to reduce the risk of adverse DDIs while treating patients for COVID-19. Commentary is also provided on issues related to specific psychiatric and nonpsychiatric medications a patient may be taking. A subsequent column will focus on DDIs between psychiatric medications and emerging COVID-19 treatments, as a detailed discussion of that topic is beyond the scope of this column.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19/drug therapy ; Comorbidity ; Drug Interactions ; Drug-Related Side Effects and Adverse Reactions/prevention & control ; Humans ; Middle Aged ; Polypharmacy ; Risk ; Substance Abuse Detection/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2020-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2022726-7
    ISSN 1538-1145 ; 1527-4160
    ISSN (online) 1538-1145
    ISSN 1527-4160
    DOI 10.1097/PRA.0000000000000502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Robotics planning in minimally invasive surgery for adult degenerative scoliosis: illustrative case.

    Pennington, Zach / Brown, Nolan J / Quadri, Saif / Pishva, Seyedamirhossein / Kuo, Cathleen C / Pham, Martin H

    Journal of neurosurgery. Case lessons

    2023  Volume 5, Issue 10

    Abstract: Background: Minimally invasive surgical techniques are changing the landscape in adult spinal deformity (ASD) surgery, enabling surgical correction to be achievable in increasingly medically complex patients. Spinal robotics are one technology that have ...

    Abstract Background: Minimally invasive surgical techniques are changing the landscape in adult spinal deformity (ASD) surgery, enabling surgical correction to be achievable in increasingly medically complex patients. Spinal robotics are one technology that have helped facilitate this. Here the authors present an illustrative case of the utility of robotics planning workflow for minimally invasive correction of ASD.
    Observations: A 60-year-old female presented with persistent and debilitating low back and leg pain limiting her function and quality of life. Standing scoliosis radiographs demonstrated adult degenerative scoliosis (ADS), with a lumbar scoliosis of 53°, a pelvic incidence-lumbar lordosis mismatch of 44°, and pelvic tilt of 39°. Robotics planning software was utilized for preoperative planning of the multiple rod and 4-point pelvic fixation in the posterior construct.
    Lessons: To the authors' knowledge, this is the first report detailing the use of spinal robotics for complex 11-level minimally invasive correction of ADS. Although additional experiences adapting spinal robotics to complex spinal deformities are necessary, the present case represents a proof-of-concept demonstrating the feasibility of applying this technology to minimally invasive correction of ASD.
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE22520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Emissions of Trichloroethylene from Bedroom Furniture Set as a Source of Indoor Air Contamination

    Bingham, Q.G. / Lutes, C. / Grand, R. / Quadri, S. / Dollhopf, R. / Posavatz, N. / Birkett, E.

    Groundwater Monitoring & Remediation. 2023 Jan., v. 43, no. 1 p.78-83

    2023  

    Abstract: Shallow trichloroethene (TCE) groundwater and soil contamination associated with a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) Superfund Site in Michigan resulted in a vapor intrusion (VI) investigation of overlying ... ...

    Abstract Shallow trichloroethene (TCE) groundwater and soil contamination associated with a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) Superfund Site in Michigan resulted in a vapor intrusion (VI) investigation of overlying condominium units. Units with data suggesting a complete VI pathway received subslab depressurization systems (SSDs). Performance monitoring following the installation of an SSD at one unit indicated that the indoor air TCE concentrations remained elevated, despite pressure field extension tests that showed the system should effectively reduce VI from soil gas. Therefore, a cost‐efficient and incremental investigation was launched to identify other potential source(s) of TCE using a field‐portable gas chromatograph/mass spectrometer (GS/MS). The combination of room‐by‐room air sampling, potential VI entry point sampling, and emission tests of potential sources were used, which resulted in successfully identifying a bedroom furniture set as an indoor source of TCE for the unit. Although many common household products are recognized as indoor sources of TCE, emissions from finished furniture products have not been widely discussed in the VI literature. The findings of this study indicate that off gassing from furniture can lead to TCE concentrations in indoor air that exceed regulatory guidelines.
    Keywords air ; air pollution ; cost effectiveness ; furniture ; gas chromatography ; groundwater ; remediation ; soil air ; soil pollution ; spectrometers ; trichloroethylene ; vapors ; Michigan
    Language English
    Dates of publication 2023-01
    Size p. 78-83.
    Publishing place Wiley Periodicals, Inc.
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2181890-3
    ISSN 1745-6592 ; 1069-3629
    ISSN (online) 1745-6592
    ISSN 1069-3629
    DOI 10.1111/gwmr.12556
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Deep Diagnosis: A Real-Time Apple Leaf Disease Detection System Based on Deep Learning

    Iqbal Khan, Asif / Quadri, S.M.K / Banday, Saba / Latief Shah, Junaid

    Computers and electronics in agriculture. 2022 May 24,

    2022  

    Abstract: Diseases and pests are one of the major reasons for low productivity of apples which in turn results in huge economic loss to the apple industry every year. Early detection of apple diseases can help in controlling the spread of infections and ensure ... ...

    Abstract Diseases and pests are one of the major reasons for low productivity of apples which in turn results in huge economic loss to the apple industry every year. Early detection of apple diseases can help in controlling the spread of infections and ensure better productivity. However, early diagnosis and identification of diseases is challenging due to many factors like, presence of multiple symptoms on same leaf, non-homogeneous background, differences in leaf colour due to age of infected cells, varying disease spot sizes etc. In this study, we first constructed an expert-annotated apple disease dataset of suitable size consisting around 9000 high quality RGB images covering all the main foliar diseases and symptoms. Next, we propose a deep learning based apple disease detection system which can efficiently and accurately identify the symptoms. The proposed system works in two stages, first stage is a tailor-made light weight classification model which classifies the input images into diseased, healthy or damaged categories and the second stage (detection stage) processing starts only if any disease is detected in first stage. Detection stage performs the actual detection and localization of each symptom from diseased leaf images. The proposed approach obtained encouraging results, reaching around 88% of classification accuracy and our best detection model achieved mAP of 42%. The preliminary results of this study look promising even on small or tiny spots. The qualitative results validate that the proposed system is effective in detecting various types of apple diseases and can be used as a practical tool by farmers and apple growers to aid them in diagnosis, quantification and follow-up of infections. Furthermore, in future, the work can be extended to other fruits and vegetables as well.
    Keywords agriculture ; apples ; color ; data collection ; disease detection ; early diagnosis ; electronics ; financial economics ; foliar diseases ; industry ; leaves ; models
    Language English
    Dates of publication 2022-0524
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 395514-x
    ISSN 0168-1699
    ISSN 0168-1699
    DOI 10.1016/j.compag.2022.107093
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Why Are Patients With COVID-19 at Risk for Drug-Drug Interactions?

    PRESKORN, SHELDON H. / QUADRI, SYEDA

    Abstract: The goal of this column is to provide information to health care professionals about drug-drug interactions (DDIs) and why DDIs are important to consider in those at serious risk of illness with Coronavirus Disease 2019 (COVID-19). Important ... ...

    Abstract The goal of this column is to provide information to health care professionals about drug-drug interactions (DDIs) and why DDIs are important to consider in those at serious risk of illness with Coronavirus Disease 2019 (COVID-19). Important considerations discussed in this column include the frequency and complexity of multiple medication use, particularly important for the older patient who often has multiple comorbid illnesses. The column covers the following issues: (1) Why patients at high risk for serious illness from COVID-19 are also at high risk for DDIs. (2) Application of results of pharmacoepidemiological studies to the population at risk for serious COVID-19 illness. (3) Mechanisms underlying DDIs, frequency and potential complexity of DDIs, and how DDIs can present clinically. (4) Methods for preventing or mitigating DDIs. (5) An introduction to the University of Liverpool drug interaction checker as a tool to reduce the risk of adverse DDIs while treating patients for COVID-19. Commentary is also provided on issues related to specific psychiatric and nonpsychiatric medications a patient may be taking. A subsequent column will focus on DDIs between psychiatric medications and emerging COVID-19 treatments, as a detailed discussion of that topic is beyond the scope of this column.
    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1097/pra.0000000000000502
    Database COVID19

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  9. Article: Aerococcus Urinae Endocarditis: A Case Report and Literature Review.

    Saeed Al-Asad, Khalid / Mazhar, Naveed / Srivastava, Shaurya / Quadri, Syed / Mitra, Subhashis

    Cureus

    2022  Volume 14, Issue 10, Page(s) e29853

    Abstract: A 75-year-old male, with a past medical history of chronic kidney disease stage 3 (CKD3) and a recent diagnosis of bilateral hydronephrosis and Foley catheter placement, presented to the emergency department for fever. Blood cultures grew Aerococcus ... ...

    Abstract A 75-year-old male, with a past medical history of chronic kidney disease stage 3 (CKD3) and a recent diagnosis of bilateral hydronephrosis and Foley catheter placement, presented to the emergency department for fever. Blood cultures grew Aerococcus urinae. Transthoracic echo (TTE) demonstrated thickened aortic valve leaflets with perforation, multiple echo densities, and severe aortic regurgitation. The patient developed decompensated congestive heart failure and cardiogenic shock. En route to surgery for emergent aortic valve replacement, the patient lost pulse and was resuscitated. The patient was subsequently transferred to the ICU where the family decided to initiate comfort care measures. This case highlights the importance and necessity of the prompt diagnosis and treatment of infective endocarditis and makes the reader aware of uncommon and rare organisms, such as Aerococcus urinae, as potential etiologies.
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 Recovery Patterns Across Alpha (B.1.1.7) and Delta (B.1.617.2) Variants of SARS-CoV-2.

    Kumar, Nitya / Quadri, Suha / AlAwadhi, Abdulla Ismaeel / AlQahtani, Manaf

    Frontiers in immunology

    2022  Volume 13, Page(s) 812606

    Abstract: Background: B.1.1.7 (alpha) and B.1.617.2 (delta) variants of concern for SARS-CoV-2 have been reported to have differential infectivity and pathogenicity. Difference in recovery patterns across these variants and the interaction with vaccination status ...

    Abstract Background: B.1.1.7 (alpha) and B.1.617.2 (delta) variants of concern for SARS-CoV-2 have been reported to have differential infectivity and pathogenicity. Difference in recovery patterns across these variants and the interaction with vaccination status has not been reported in population-based studies.
    Objective: The objective of this research was to study the length of stay and temporal trends in RT-PCR cycle times (Ct) across alpha and delta variants of SARS-CoV-2 between vaccinated and unvaccinated individuals.
    Methods: Participants consisted of patients admitted to national COVID-19 treatment facilities if they had a positive RT-PCR test for SARS-CoV-2, and analysis of variants was performed (using whole genome sequencing). Information on vaccination status, age, sex, cycle times (Ct) for four consecutive RT-PCR tests conducted during hospital stay, and total length of hospital stay for each participant were ascertained from electronic medical records.
    Results: Patients infected with the delta variant were younger (mean age = 35years vs 39 years for alpha, p<0.001) and had lesser vaccination coverage (54% vs 72% for alpha, p<0.001). RT-PCR Ct values were similar for both variants at the baseline test; however by the fourth test, delta variant patients had significantly lower Ct values (27 vs 29, p=0.05). Length of hospital stay was higher in delta variant patients in vaccinated (3 days vs 2.9 days for alpha variant) as well as in unvaccinated patients (5.2 days vs 4.4 days for alpha variant, p<0.001). Hazards of hospital discharge after adjusting for vaccination status, age, and sex was higher for alpha variant infections (HR=1.2, 95% CI: 1.01-1.41, p=0.029).
    Conclusion: Patients infected with the delta variant of SARS-CoV-2 were found to have a slower recovery as indicated by longer length of stay and higher shedding of the virus compared to alpha variant infections, and this trend was consistent in both vaccinated and unvaccinated patients.
    MeSH term(s) Adult ; Age Factors ; Bahrain/epidemiology ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Female ; Humans ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; Vaccination/statistics & numerical data
    Language English
    Publishing date 2022-02-14
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.812606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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