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  1. Article ; Conference proceedings: Clinical case report: headache due to cerebrospinal fluid hypotension treated with caffeine

    Monteiro, Nicholas Pili / Souza, Vitor Reis de / de Quadros, Fernanda Silveira / Barea, Liselotte Menke / Scornavacca, Francisco

    Arquivos de Neuro-Psiquiatria

    2023  Volume 81, Issue S 01

    Event/congress SBN Conference 2022, Expo United Curitiba, 2022-11-09
    Language English
    Publishing date 2023-09-01
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 418916-4
    ISSN 1678-4227 ; 0004-282X
    ISSN (online) 1678-4227
    ISSN 0004-282X
    DOI 10.1055/s-0043-1774498
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: A novel DMD intronic alteration: a potentially disease-causing variant of an intermediate muscular dystrophy phenotype.

    Santin, Ricardo / Vieira, Igor Araujo / Nunes, Jean Costa / Benevides, Maria Luiza / Quadros, Fernanda / Brusius-Facchin, Ana Carolina / Macedo, Gabriel / Bertoni, Ana Paula Santin

    Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology

    2021  Volume 40, Issue 2, Page(s) 93–100

    Abstract: Pathogenic germline variants ... ...

    Abstract Pathogenic germline variants in
    MeSH term(s) Dystrophin/genetics ; Genetic Testing ; Humans ; Introns/genetics ; Muscular Dystrophy, Duchenne/genetics ; Mutation ; Phenotype
    Chemical Substances Dystrophin
    Language English
    Publishing date 2021-06-30
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 2102328-1
    ISSN 2532-1900 ; 1128-2460
    ISSN (online) 2532-1900
    ISSN 1128-2460
    DOI 10.36185/2532-1900-048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Preparation, structural, microstructural, mechanical and cytotoxic characterization of as-cast Ti-25Ta-Zr alloys.

    Kuroda, Pedro Akira Bazaglia / de Freitas Quadros, Fernanda / Sousa, Karolyne Dos Santos Jorge / Donato, Tatiani Ayako Goto / de Araújo, Raul Oliveira / Grandini, Carlos Roberto

    Journal of materials science. Materials in medicine

    2020  Volume 31, Issue 2, Page(s) 19

    Abstract: Titanium alloys have been widely used as biomaterials, especially for orthopedic prostheses and dental implants, but these materials have Young's modulus almost three times greater than human cortical bones. Because of this, new alloys are being produced ...

    Abstract Titanium alloys have been widely used as biomaterials, especially for orthopedic prostheses and dental implants, but these materials have Young's modulus almost three times greater than human cortical bones. Because of this, new alloys are being produced for the propose of decreasing Young's modulus to achieve a more balanced mechanical compatibility with the bone. In this paper, it is reported the development of Ti-25Ta alloys as a base material, in which was introduced zirconium, with concentration varying between 0 and 40 wt%, with the aim of biomedical applications. The alloys were prepared in an arc-melting furnace. The microstructural analysis was performed by x-ray diffraction as well as optical and scanning electron microscopy. Selected mechanical properties were analyzed by microhardness and Young's modulus measurements, and cytotoxicity analysis by indirect test. X-ray measurements revealed the presence of α″ phase in the alloy without zirconium; α″ + β phases for alloys with 10, 20, and 30 wt% of zirconium, and β phase only for the alloy with 40 wt% of zirconium. These results were corroborated by the microscopy results. The hardness of the alloy was higher than that of cp-Ti due to the actions of zirconium and tantalum as hardening agents. The Young's modulus decreases with high levels of zirconium due to the stabilization of the β phase. The cytotoxicity test showed that the extracts of studied alloys are not cytotoxic for osteoblast cells in short periods of culture.
    MeSH term(s) Alloys/chemistry ; Alloys/toxicity ; Animals ; Cell Survival ; Materials Testing ; Mice ; Osteoblasts/drug effects ; Tantalum/chemistry ; Titanium/chemistry ; Zirconium/chemistry
    Chemical Substances Alloys ; Tantalum (6424HBN274) ; Zirconium (C6V6S92N3C) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2020-01-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1031752-1
    ISSN 1573-4838 ; 0957-4530
    ISSN (online) 1573-4838
    ISSN 0957-4530
    DOI 10.1007/s10856-019-6350-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effect of Thermomechanical Treatments on the Phases, Microstructure, Microhardness and Young's Modulus of Ti-25Ta-Zr Alloys.

    Kuroda, Pedro Akira Bazaglia / Quadros, Fernanda de Freitas / Araújo, Raul Oliveira de / Afonso, Conrado Ramos Moreira / Grandini, Carlos Roberto

    Materials (Basel, Switzerland)

    2019  Volume 12, Issue 19

    Abstract: Titanium and its alloys currently are used as implants, possessing excellent mechanical properties (more suited than stainless steel and Co-Cr alloys), good corrosion resistance and good biocompatibility. The titanium alloy used for most biomedical ... ...

    Abstract Titanium and its alloys currently are used as implants, possessing excellent mechanical properties (more suited than stainless steel and Co-Cr alloys), good corrosion resistance and good biocompatibility. The titanium alloy used for most biomedical applications is Ti-6Al-4V, however, studies showed that vanadium and aluminum cause allergic reactions in human tissues and neurological disorders. New titanium alloys without the presence of these elements are being studied. The objective of this study was to analyze the influence of thermomechanical treatments, such as hot-rolling, annealing and solution treatment in the structure, microstructure and mechanical properties of the Ti-25Ta-Zr ternary alloy system. The structural and microstructural analyses were performed using X-ray diffraction, as well as optical, scanning and transmission electron microscopy. The mechanical properties were analyzed using microhardness and Young's modulus measurements. The results showed that the structure of the materials and the mechanical properties are influenced by the different thermal treatments: rapid cooling treatments (hot-rolling and solubilization) induced the formation of α" and β phases, while the treatments with slow cooling (annealing) induced the formation of martensite phases. Alloys in the hot-rolled and solubilized conditions have better mechanical properties results, such as low elastic modulus, due to retention of the β phase in these alloys.
    Language English
    Publishing date 2019-09-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma12193210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Análise de tendências das taxas de mortalidade infantil e de seus fatores de risco na cidade de Porto Alegre, Rio Grande do Sul, Brasil, no período de 1996 a 2008.

    Hernandez, Alessandra Rivero / Silva, Clécio Homrich da / Agranonik, Marilyn / Quadros, Fernanda Maciel de / Goldani, Marcelo Zubaran

    Cadernos de saude publica

    2011  Volume 27, Issue 11, Page(s) 2188–2196

    Abstract: The aim of this article was to determine trends in infant mortality and related risk factors in Porto Alegre, Rio Grande do Sul State, Brazil. The study was based on data from a live birth and infant death registry for the years 1996 to 2008. Times ... ...

    Title translation Analysis of infant mortality trends and risk factors in Porto Alegre, Rio Grande do Sul State, Brazil, 1996-2008.
    Abstract The aim of this article was to determine trends in infant mortality and related risk factors in Porto Alegre, Rio Grande do Sul State, Brazil. The study was based on data from a live birth and infant death registry for the years 1996 to 2008. Times trends were analyzed for overall and partial infant mortality rates according to maternal schooling, number of prenatal visits, maternal age, number of live and dead children, sex of the newborn, type of delivery, birth weight, and type of hospital. Poisson regression was used to estimate the influence of socioeconomic status and other risk factors. The infant mortality rate dropped among mothers with less than 11 years of schooling. There were no significant changes among newborns of mothers with 12 or more years of schooling. Maternal socioeconomic status was the factor most closely associated with the reduction in infant mortality. Still, the downward trend failed to achieve its full potential, due to the increase in low birth weight.
    MeSH term(s) Brazil/epidemiology ; Educational Status ; Female ; Humans ; Infant ; Infant Mortality/trends ; Infant, Low Birth Weight ; Infant, Newborn ; Live Birth/epidemiology ; Risk Factors ; Socioeconomic Factors ; Urban Population
    Language Portuguese
    Publishing date 2011-10-29
    Publishing country Brazil
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1115730-6
    ISSN 1678-4464 ; 0102-311X
    ISSN (online) 1678-4464
    ISSN 0102-311X
    DOI 10.1590/s0102-311x2011001100012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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