LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 32

Search options

  1. Article ; Online: Efficacy of insulin in treating severe hypertriglyceridaemia in the third trimester of pregnancy

    Dong Zhou / Guoqiang Sun / Jing Hu / Quan Gan

    Frontiers in Medicine, Vol

    2022  Volume 9

    Abstract: This study aims to investigate the efficacy of insulin in treating severe hypertriglyceridaemia (HTG) during the third trimester of pregnancy. Women with severe HTG (TG ≥ 11.30 mmol/L) in the third trimester of pregnancy who received clinical examination ...

    Abstract This study aims to investigate the efficacy of insulin in treating severe hypertriglyceridaemia (HTG) during the third trimester of pregnancy. Women with severe HTG (TG ≥ 11.30 mmol/L) in the third trimester of pregnancy who received clinical examination and delivered in Hubei Maternal and Child Health Hospital from 01 January 2017 to 30 September 2021 were recruited. Patients with TG ≥ 11.30 mmol/L at 30–32 weeks of gestation were treated with a low-fat diet and insulin as the insulin treatment group. For the control group, patients with TGs of 5.65–11.30 mmol/L at 30–32 weeks of gestation who developed severe HTG (TG ≥ 11.30 mmol/L) before delivery were treated with a low-fat diet only. General maternal information, delivery, perinatal treatment and laboratory examination information were collected from electronic medical records and compared. We found that in the insulin treatment group, there were higher values of progestational body mass index (BMI) (Z = −2.281, P = 0.023), higher incidence of diabetes (χ2 = 20.618, P < 0.001) and higher incidence of fatty liver (χ2 = 4.333, P = 0.037) than in the control group but also a higher pregnancy weight gain compliance rate (χ2 = 4.061, P = 0.044). Laboratory examination before delivery revealed that compared with the control group, insulin treatment significantly decreased prenatal TG (Z = −10.392, P < 0.001), cholesterol (Z = −8.494, P < 0.001), low-density lipoprotein (Z = −3.918, P < 0.001), apolipoprotein A1 (t = 2.410, P = 0.019), cystatin (Z = −4.195, P < 0.001), incidence of hypocalcaemia (P = 0.036), and absolute number of lymphocytes (Z = −3.426, P = 0.001). Delivery outcomes were also improved in the insulin treatment group compared with the control group, including lower neonatal weight (Z = −2.200, P = 0.028), incidence of macrosomia (χ2 = 4.092, P = 0.043), gestational age (Z = −3.427, P = 0.001), and rate of intensive care unit (ICU) conversion (P = 0.014). In conclusion, insulin therapy for HTG in the third trimester of pregnancy ...
    Keywords insulin ; third trimester ; severe ; curative effect ; hypertriglyceridaemia ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Fault zone exploitation in geothermal reservoirs

    Kingsley Anyim / Quan Gan

    Advances in Geo-Energy Research, Vol 4, Iss 1, Pp 1-

    Production optimization, permeability evolution and induced seismicity

    2020  Volume 12

    Abstract: This study employs a coupled thermal-hydrological-mechanical model to investigate the permeability evolution and fault reactivation of a critically stressed fault in geothermal reservoir. The fracture permeability sensitivity analysis for permeabilities ... ...

    Abstract This study employs a coupled thermal-hydrological-mechanical model to investigate the permeability evolution and fault reactivation of a critically stressed fault in geothermal reservoir. The fracture permeability sensitivity analysis for permeabilities of the fault damage zone that hydro-mechanical processes have dominating control on permeability evolution and the associated timing of slip on the fault plane for high fracture permeability. The mode of thermal sweep in the reservoir is dominated by advection, as the high fracture permeability permitted higher velocity of fluid flow. For the condition of low fracture permeability, heat transfer process has pronounced control on permeability evolution and timing of slip due to heat conduction process. With reduction in fluid flow and hydromechanical effects, heat transfer in the reservoir is dominated by heat conduction, as the temperature difference between the fault zone and the country rock becomes negligible. For the intermediate fracture permeabilities, the induced thermal unloading due to conduction could prompt the onset of failure. Changing the locations of the injection well along the fault zone shows that shear failure on the fault/fracture plane occurs earlier for lower stress state and vice versa. The evolutions of production rate and power generation are also influenced by the stress state at the injection and production wells. The elevated pore pressures in the fault zone due to fluid injection causes distributed seismicity on the fault/fracture planes which all have moment magnitudes that are below 2.5.
    Keywords fault reactivation ; geothermal reservoirs ; production optimization ; permeability evolution ; induced seismicity ; Engineering geology. Rock mechanics. Soil mechanics. Underground construction ; TA703-712 ; Geophysics. Cosmic physics ; QC801-809 ; Commercial geography. Economic geography ; HF1021-1027
    Subject code 550
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Ausasia Science and Technology Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Location-scale portfolio selection with factor-recentered skew normal asset returns

    Quan Gan

    Journal of economic dynamics & control Vol. 48 , p. 176-187

    2014  Volume 48, Page(s) 176–187

    Author's details Quan Gan
    Keywords Portfolio selection ; Skew normal ; Certainty equivalent ; Non-monotonicity ; Factor model
    Language English
    Size graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam [u.a.]
    Document type Article
    ZDB-ID 717409-3
    ISSN 0165-1889
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Optimal selling mechanism, auction discounts and time on market

    Quan Gan

    Real estate economics : journal of the American Real Estate and Urban Economics Association Vol. 41, No. 2 , p. 347-383

    2013  Volume 41, Issue 2, Page(s) 347–383

    Author's details Quan Gan
    Keywords Immobilienmarkt ; Auktionstheorie ; Zeit ; Risikoaversion
    Language English
    Size graph. Darst.
    Publisher AREUEA
    Publishing place Bloomington, Ind
    Document type Article
    ZDB-ID 1234653-6 ; 2094119-5
    ISSN 1540-6229 ; 0270-0484 ; 1080-8620
    ISSN (online) 1540-6229
    ISSN 0270-0484 ; 1080-8620
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Analysis of the Underlying Mechanism of the Jiu Wei Zhen Xin Formula for Treating Generalized Anxiety Disorder Based on Network Pharmacology of Traditional Chinese Medicine

    Heng Shao / Quan Gan / Zhuangfei Chen / Shasha Zhu / Yanqing Zhu

    Evidence-Based Complementary and Alternative Medicine, Vol

    2022  Volume 2022

    Abstract: Currently, there are many effective pharmacological treatments for generalized anxiety disorder (GAD), formulated herbal granule is also an alternative way. Our research intends to construct a pharmacological network on genetic targets and pathways ... ...

    Abstract Currently, there are many effective pharmacological treatments for generalized anxiety disorder (GAD), formulated herbal granule is also an alternative way. Our research intends to construct a pharmacological network on genetic targets and pathways between Jiu Wei Zhen Xin Formula (JWZXF) and GAD. Through the TCMSP database, we collected the active ingredients of JWZXF and potential targets of the active ingredients. The GAD-related proteins collected from GeneCards database and DisGeNET database were combined. Component-target protein networks were constructed and visualized using Cytoscape 3.8.2 software to comprehensively clarify the relationships between ingredients, components, and targets. The intersection targets were imported into the STRING database, and the protein-protein interaction (PPI) network was constructed. We constructed and analyzed the visualized “drug-target-disease” network. Gene Ontology (GO) enrichment together with Kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis were conducted on the common target through R language. Forty-one effective components and 106 potential targets of JWZXF were found. There were top ten hub genes and multiple important signaling pathways involved in the treatment of GAD with the JWZXF. This study expounded the pharmacological actions and molecular mechanisms of the JWZXF in treating GAD from a holistic perspective. The potential pharmacological effects of the JWZXF are closely related to regulation because not only does it comprehensively analyze the possible mechanism of JWZXF treatment of GAD but it can also facilitate further in-depth research and provide a theoretical basis for the clinical expansion of its application.
    Keywords Other systems of medicine ; RZ201-999
    Subject code 570
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Hierarchical communication of chirality for aromatic oligoamide sequences

    Jiajia Zhang / Dan Luo / Chunmiao Ma / Lu Huang / Quan Gan

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 7

    Abstract: Communication of chirality at a molecular level is the fundamental for transmitting chirality information but one-step communication modes in many artificial systems limits further processing the chirality information. Here, the authors report chirality ... ...

    Abstract Communication of chirality at a molecular level is the fundamental for transmitting chirality information but one-step communication modes in many artificial systems limits further processing the chirality information. Here, the authors report chirality communication of aromatic oligoamide sequences within interpenetrated helicate architecture in a hierarchical manner.
    Keywords Science ; Q
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Does the probability of informed trading model fit empirical data?

    Quan Gan / Wang Chun Wei / Johnstone, David

    The financial review : the official publication of the Eastern Finance Association Vol. 52, No. 1 , p. 5-35

    2017  Volume 52, Issue 1, Page(s) 5–35

    Author's details Quan Gan, Wang Chun Wei, David Johnstone
    Keywords PIN ; dependence structure ; copula ; mixture model ; Rosenblatt's transformation ; goodness-of-fit test
    Language English
    Publisher Blackwell
    Publishing place Malden, Mass. [u.a.]
    Document type Article
    ZDB-ID 864322-2 ; 2068470-8
    ISSN 1540-6288 ; 0732-8516
    ISSN (online) 1540-6288
    ISSN 0732-8516
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Quantum plasmonics pushes chiral sensing limit to single molecules

    Chi Zhang / Huatian Hu / Chunmiao Ma / Yawen Li / Xujie Wang / Dongyao Li / Artur Movsesyan / Zhiming Wang / Alexander Govorov / Quan Gan / Tao Ding

    Nature Communications, Vol 15, Iss 1, Pp 1-

    a paradigm for chiral biodetections

    2024  Volume 8

    Abstract: Abstract Chiral sensing of single molecules is vital for the understanding of chirality and their applications in biomedicine. However, current technologies face severe limitations in achieving single-molecule sensitivity. Here we overcome these ... ...

    Abstract Abstract Chiral sensing of single molecules is vital for the understanding of chirality and their applications in biomedicine. However, current technologies face severe limitations in achieving single-molecule sensitivity. Here we overcome these limitations by designing a tunable chiral supramolecular plasmonic system made of helical oligoamide sequences (OS) and nanoparticle-on-mirror (NPoM) resonator, which works across the classical and quantum regimes. Our design enhances the chiral sensitivity in the quantum tunnelling regime despite of the reduced local E-field, which is due to the strong Coulomb interactions between the chiral OSs and the achiral NPoMs and the additional enhancement from tunnelling electrons. A minimum of four molecules per single-Au particle can be detected, which allows for the detection of an enantiomeric excess within a monolayer, manifesting great potential for the chiral sensing of single molecules.
    Keywords Science ; Q
    Subject code 539
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: 3D Cascaded Convolutional Networks for Multi-vertebrae Segmentation.

    Xia, Liu / Xiao, Liu / Quan, Gan / Bo, Wang

    Current medical imaging

    2020  Volume 16, Issue 3, Page(s) 231–240

    Abstract: Background: Automatic approach to vertebrae segmentation from computed tomography (CT) images is very important in clinical applications. As the intricate appearance and variable architecture of vertebrae across the population, cognate constructions in ... ...

    Abstract Background: Automatic approach to vertebrae segmentation from computed tomography (CT) images is very important in clinical applications. As the intricate appearance and variable architecture of vertebrae across the population, cognate constructions in close vicinity, pathology, and the interconnection between vertebrae and ribs, it is a challenge to propose a 3D automatic vertebrae CT image segmentation method.
    Objective: The purpose of this study was to propose an automatic multi-vertebrae segmentation method for spinal CT images.
    Methods: Firstly, CLAHE-Threshold-Expansion was preprocessed to improve image quality and reduce input voxel points. Then, 3D coarse segmentation fully convolutional network and cascaded finely segmentation convolutional neural network were used to complete multi-vertebrae segmentation and classification.
    Results: The results of this paper were compared with the other methods on the same datasets. Experimental results demonstrated that the Dice similarity coefficient (DSC) in this paper is 94.84%, higher than the V-net and 3D U-net.
    Conclusion: Method of this paper has certain advantages in automatically and accurately segmenting vertebrae regions of CT images. Due to the easy acquisition of spine CT images. It was proven to be more conducive to clinical application of treatment that uses our segmentation model to obtain vertebrae regions, combining with the subsequent 3D reconstruction and printing work.
    MeSH term(s) Adolescent ; Adult ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Male ; Neural Networks, Computer ; Radiographic Image Interpretation, Computer-Assisted/methods ; Spinal Injuries/diagnostic imaging ; Spine/diagnostic imaging ; Tomography, X-Ray Computed/methods ; Young Adult
    Language English
    Publishing date 2020-03-05
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/1573405615666181204151943
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Latitudinal- and height-dependent long-term climatology of propagating quasi-16-day waves in the troposphere and stratosphere

    Wentao Tang / Shaodong Zhang / Chunming Huang / Kaiming Huang / Yun Gong / Quan Gan

    Earth, Planets and Space, Vol 73, Iss 1, Pp 1-

    2021  Volume 16

    Abstract: Abstract The global amplitude of the westward propagating quasi-16-day waves (16DW) with wavenumber 1 (Q16W1), the strongest component of 16DW, are derived from the European Centre for Medium-Range Weather Forecasts ERA-Interim reanalysis temperature and ...

    Abstract Abstract The global amplitude of the westward propagating quasi-16-day waves (16DW) with wavenumber 1 (Q16W1), the strongest component of 16DW, are derived from the European Centre for Medium-Range Weather Forecasts ERA-Interim reanalysis temperature and zonal wind data sets from February 1979 to January 2018. In terms of temperature and zonal wind, strong climatologically average amplitudes of Q16W1 appear in the upper stratosphere at mid–high latitudes in both hemispheres, and the wave amplitude is stronger in the Northern Hemisphere (NH) than in the Southern Hemisphere (SH). Multivariate linear regression is separately applied to calculate the responses of the Q16W1 temperature and zonal wind amplitudes to the QBO (quasi-biennial oscillation), ENSO (El Niño-Southern Oscillation), solar activity and linear trends of the Q16W1 amplitude. The QBO signatures of the Q16W1 temperature and zonal wind amplitudes are mainly located in the stratosphere. The Q16W1 has significant QBO responses at low latitudes. In addition, only the temperature amplitude presents a larger QBO signature in its strongest climatological amplitude region. No significant responses to ENSO and solar activity are observed in temperature and zonal wind amplitudes. The linear trends of the monthly mean Q16W1 temperature and zonal wind amplitude are generally positive, especially in the mid-upper stratosphere. The trend is asymmetric about the equator and significantly stronger in the NH than in the SH. The seasonal variation in the trend of the temperature amplitude is studied and illustrated to be stronger in winter and weaker in spring and autumn. Further investigation suggests that the background and local instability trends contribute most of the increasing trend of the Q16W1 amplitude. In winter in both hemispheres, a weakening trend of eastward zonal wind provides more favourable background wind for Q16W1 upward propagation, in autumn and winter in the NH and in spring, autumn and winter in the SH, and the increasing trend of local ...
    Keywords Quasi-16-day waves ; Long-term trend ; Geography. Anthropology. Recreation ; G ; Geodesy ; QB275-343 ; Geology ; QE1-996.5
    Subject code 551
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top