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Artikel ; Online: National taxation on sugar-sweetened beverages and its association with overweight, obesity, and diabetes.

Sassano, Michele / Castagna, Carolina / Villani, Leonardo / Quaranta, Gianluigi / Pastorino, Roberta / Ricciardi, Walter / Boccia, Stefania

The American journal of clinical nutrition

2024 Band 119, Heft 4, Seite(n) 990–1006

Abstract: Background: Consumption of sugar-sweetened beverages (SSBs) has been linked to several adverse health outcomes, thus many countries introduced taxation to reduce it.: Objectives: To summarize national SSB taxation laws and to assess their association ...

Abstract	Background: Consumption of sugar-sweetened beverages (SSBs) has been linked to several adverse health outcomes, thus many countries introduced taxation to reduce it. Objectives: To summarize national SSB taxation laws and to assess their association with obesity, overweight and diabetes. Methods: We conducted a systematic scoping review up to January 2022 on PubMed, Web of Science, Embase, and Google Search to identify taxes on SSBs. An interrupted time series analysis (ITSA) was conducted on 17 countries with taxation implemented in 2013 or before to evaluate the level and slope modifications in the rate of change of standardized prevalence rates of overweight, obesity, and diabetes. Random-effects meta-regression was used to assess whether year of entry into force of the law, national income, and tax design affected observed results. Results: We included 76 tax laws issued between 1940 and 2020 by 43 countries, which were heterogeneous in terms of tax design, amount, and taxed products. Among children and adolescents, ITSA showed level or slope reduction for prevalence of overweight and obesity in 5 (Brazil, Samoa, Palau, Panama, Tonga) and 6 (El Salvador, Uruguay, Nauru, Norway, Palau, Tonga) countries out of 17, respectively. No clear pattern of modification of results according to investigated factors emerged from the meta-regression analysis. Conclusions: Taxation is highly heterogeneous across countries in terms of products and design, which might influence its effectiveness. Our findings provide some evidence regarding a deceleration of the increasing prevalence rates of overweight and obesity among children occurring in some countries following introduction of taxation. PROSPERO registration number: CRD42021233309.
Mesh-Begriff(e)	Adolescent ; Child ; Humans ; Overweight/epidemiology ; Sugar-Sweetened Beverages/adverse effects ; Obesity/epidemiology ; Obesity/etiology ; Taxes ; Diabetes Mellitus ; Beverages/adverse effects
Sprache	Englisch
Erscheinungsdatum	2024-02-26
Erscheinungsland	United States
Dokumenttyp	Systematic Review ; Journal Article
ZDB-ID	280048-2
ISSN	1938-3207 ; 0002-9165
ISSN (online)	1938-3207
ISSN	0002-9165
DOI	10.1016/j.ajcnut.2023.12.013
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Polygenic risk prediction models for colorectal cancer: a systematic review.

Sassano, Michele / Mariani, Marco / Quaranta, Gianluigi / Pastorino, Roberta / Boccia, Stefania

BMC cancer

2022 Band 22, Heft 1, Seite(n) 65

Abstract: Background: Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is ... ...

Abstract	Background: Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to evaluate the improvement of discriminatory accuracy when adding SNPs to a prediction model with only traditional risk factors. Methods: We conducted a systematic review on prediction models incorporating multiple SNPs for CRC risk prediction. We tested whether a significant trend in the increase of Area Under Curve (AUC) according to the number of SNPs could be observed, and estimated the correlation between AUC improvement and number of SNPs. We estimated pooled AUC improvement for SNP-enhanced models compared with non-SNP-enhanced models using random effects meta-analysis, and conducted meta-regression to investigate the association of specific factors with AUC improvement. Results: We included 33 studies, 78.79% using genetic risk scores to combine genetic data. We found no significant trend in AUC improvement according to the number of SNPs (p for trend = 0.774), and no correlation between the number of SNPs and AUC improvement (p = 0.695). Pooled AUC improvement was 0.040 (95% CI: 0.035, 0.045), and the number of cases in the study and the AUC of the starting model were inversely associated with AUC improvement obtained when adding SNPs to a prediction model. In addition, models constructed in Asian individuals achieved better AUC improvement with the incorporation of SNPs compared with those developed among individuals of European ancestry. Conclusions: Though not conclusive, our results provide insights on factors influencing discriminatory accuracy of SNP-enhanced models. Genetic variants might be useful to inform stratified CRC screening in the future, but further research is needed.
Mesh-Begriff(e)	Adult ; Area Under Curve ; Asian People/genetics ; Case-Control Studies ; Clinical Decision Rules ; Colorectal Neoplasms/ethnology ; Colorectal Neoplasms/genetics ; Female ; Genetic Predisposition to Disease/ethnology ; Genetic Predisposition to Disease/genetics ; Genome-Wide Association Study ; Humans ; Male ; Middle Aged ; Multifactorial Inheritance/genetics ; Polymorphism, Single Nucleotide/genetics ; Risk Assessment ; Risk Factors ; White People/genetics
Sprache	Englisch
Erscheinungsdatum	2022-01-15
Erscheinungsland	England
Dokumenttyp	Journal Article ; Systematic Review
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-021-09143-2
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Use of oxygen-ozone therapy to improve the effectiveness of antibiotic treatment on infected arthroplasty: protocol for a superiority, open-label, multicentre, randomised, parallel trial.

Cascini, Fidelia / Franzini, Marianno / Andreoli, Arnaldo / Manzotti, Alfonso / Cadeddu, Chiara / Quaranta, Gianluigi / Gentili, Andrea / Ricciardi, Walter

BMJ open

2024 Band 14, Heft 1, Seite(n) e076739

Abstract: Introduction: Surgical site infections still remain a major public health challenge and have become an increasing universal risk, especially for the implantation of orthopaedic devices.Unfortunately, the discovery and increasingly widespread use ( ... ...

Abstract	Introduction: Surgical site infections still remain a major public health challenge and have become an increasing universal risk, especially for the implantation of orthopaedic devices.Unfortunately, the discovery and increasingly widespread use (especially the misuse) of antibiotics have led to the rapid appearance of antibiotic-resistant strains today; more and more infections are caused by microorganisms that fail to respond to conventional treatments.Oxygen-ozone therapy has been extensively used and studied for decades across various potential medical applications and has provided consistent effects with minimal side effects.This study aims to determine the superiority of oxygen-ozone therapy in combination with oral antibiotic therapy in patients with wound infections after an orthopaedic device implantation when compared with antibiotic therapy alone. Methods and analysis: This is an open-label, multicentre, randomised, parallel-group study that aims to assess the efficacy and safety of oxygen-ozone therapy in combination with oral antibiotic therapy to treat infections in patients (male or female aged ≥18 years) having undergone surgery for the implant of an orthopaedic device. Patients must have at least one (but no more than three) postoperative wounds in the site of surgery (ulcers, eschars and sores) and at least one symptom (pain, burning, redness and malodour) and at least one sign (erythema, local warmth, swelling and purulent secretion) of infection of at least moderate intensity (score ≥2) in the target lesion at the screening visit (patients with wounds without signs of localised infection or with undermining wounds will be excluded).Patients (n=186) will be recruited from five Italian hospitals and studied for 7 weeks. All will be assigned to one of the two treatment groups according to a web-based, centralised randomisation procedure and placed into either the (1) intervention: oxygen-ozone therapy 2-3 times a week for 6 weeks (for a maximum of 15 sessions) simultaneously with an appropriate oral antibiotic therapy prescribed at baseline or (2) control: oral antibiotic therapy prescribed at baseline.The primary outcome is the efficacy and superiority of the treatment (ozone and oral antibiotic therapies); secondary outcomes include the resolution of signs and symptoms, modifications in lesion size and the treatment's safety and tolerability. Ethics and dissemination: This study has been reviewed and approved by the responsible Independent Ethics Committee (IEC) of COMITATO ETICO CAMPANIA NORD, located at 'Azienda Ospedaliera San Giuseppe Moscati di Avellino'.After completion of the study, the project coordinator will prepare a draft manuscript containing the final results of the study on the basis of the statistical analysis. The manuscript will be derived by the co-authors for comments, and after revision, it will be sent to a major scientific journal. Findings will be disseminated via online and print media, events and peer-reviewed journals. Trial registration number: NCT04787575.
Mesh-Begriff(e)	Adolescent ; Adult ; Female ; Humans ; Male ; Anti-Bacterial Agents ; Arthroplasty ; Multicenter Studies as Topic ; Oxygen ; Ozone/therapeutic use ; Randomized Controlled Trials as Topic ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/prevention & control ; Treatment Outcome ; Equivalence Trials as Topic
Chemische Substanzen	Anti-Bacterial Agents ; Oxygen (S88TT14065) ; Ozone (66H7ZZK23N)
Sprache	Englisch
Erscheinungsdatum	2024-01-04
Erscheinungsland	England
Dokumenttyp	Clinical Trial Protocol ; Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-076739
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: La sicurezza alimentare nello “street food”: un’esperienza nella città di Roma.

Quaranta, Gianluigi / Nardone, Ida / Laurenti, Patrizia

Igiene e sanita pubblica

2016 Band 72, Heft 5, Seite(n) 429–441

Abstract: The Authors describe the results of inspections carried out in 22 street food outlets in the city of Rome, Italy, from 7 April to 28 May 2014. In general, structural requirements of outlets were met but some critical aspects related to hygiene, in ... ...

Titelübersetzung	Street food safety in Rome, Italy.
Abstract	The Authors describe the results of inspections carried out in 22 street food outlets in the city of Rome, Italy, from 7 April to 28 May 2014. In general, structural requirements of outlets were met but some critical aspects related to hygiene, in particular of instruments, surfaces and worktops, were identified. Results suggest the need to ensure compliance with sanitation requirements of this particular type of food outlet, in order to ensure food safety and, consequently, consumers' health.
Mesh-Begriff(e)	Checklist ; Food Safety ; Food Services/standards ; Rome
Sprache	Italienisch
Erscheinungsdatum	2016-09
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ISSN	0019-1639
ISSN	0019-1639
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: La sicurezza igienica del latte in polvere per la prima infanzia nella realtà ospedaliera.

Quaranta, Gianluigi / Posteraro, Brunella / Cambieri, Andrea / Berloco, Filippo / Vincenti, Sara / Turnaturi, Cinzia / Laurenti, Patrizia

Igiene e sanita pubblica

2019 Band 74, Heft 5, Seite(n) 433–442

Abstract: The authors present the results of a study whose aim was to assess the hygienic quality of powder and reconstituted milk for early childhood, in a University General Hospital in Rome, Italy. This procedure is an integral part of the systematic ... ...

Titelübersetzung	Hygienic safety of infant milk powder formulas in hospital setting.
Abstract	The authors present the results of a study whose aim was to assess the hygienic quality of powder and reconstituted milk for early childhood, in a University General Hospital in Rome, Italy. This procedure is an integral part of the systematic verification activities that the hospital Health Management department considers as a priority for patient safety. The absence of contamination in all tested samples confirms the suitability of adopted procedures to ensure a safe product, considering the increased vulnerability of newborns, especially if preterm.
Mesh-Begriff(e)	Female ; Food Contamination/prevention & control ; Food Safety ; Humans ; Hygiene ; Infant ; Infant Formula/standards ; Infant, Newborn ; Italy ; Male ; Rome
Sprache	Italienisch
Erscheinungsdatum	2019-02-19
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ISSN	0019-1639
ISSN	0019-1639
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Knowledge and beliefs about vaccination in pregnant women before and during the COVID-19 pandemic.

Bruno, Stefania / Nachira, Lorenza / Villani, Leonardo / Beccia, Viria / Di Pilla, Andrea / Pascucci, Domenico / Quaranta, Gianluigi / Carducci, Brigida / Spadea, Antonietta / Damiani, Gianfranco / Lanzone, Antonio / Federico, Bruno / Laurenti, Patrizia

Frontiers in public health

2022 Band 10, Seite(n) 903557

Abstract: Introduction: Vaccine hesitancy threatens the health of populations and challenges Public Health professionals. Strategies to reduce it aim to improve people's risk perception about vaccine-preventable diseases, fill knowledge gaps about vaccines and ... ...

Abstract	Introduction: Vaccine hesitancy threatens the health of populations and challenges Public Health professionals. Strategies to reduce it aim to improve people's risk perception about vaccine-preventable diseases, fill knowledge gaps about vaccines and increase trust in healthcare providers. During pregnancy, educational interventions can provide a proper knowledge about safety and efficacy of maternal and childhood vaccinations. Fighting hesitancy and clarifying doubts is fundamental during the COVID-19 pandemic, which may have affected people's knowledge and beliefs toward vaccination. This study aimed at assessing if the advent of the pandemic was associated with changes in pregnant women's knowledge and beliefs toward vaccination, and trust in healthcare services. Methods: A repeated cross-sectional study was conducted through self-reported questionnaires in a Roman teaching hospital, where educational classes about vaccinations are routinely held as part of a birthing preparation course. Data were collected on a sample of pregnant women before and during the pandemic. Free-of-charge flu vaccinations were offered to all course participants and adherence to flu vaccination was assessed. Results: The proportion of pregnant women reporting that vaccines have mild side effects and that are sufficiently tested increased from 78.6 to 92.0% ( Conclusions: The pandemic may have positively affected pregnant women's knowledge and opinions about vaccinations and trust in HCWs, despite a possible negative impact on their perceptions about NHS operators. This should inspire Public Health professionals to rethink their role as health communicators.
Mesh-Begriff(e)	COVID-19/prevention & control ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Influenza Vaccines ; Pandemics ; Pregnancy ; Pregnant Women ; State Medicine ; Vaccination
Chemische Substanzen	Influenza Vaccines
Sprache	Englisch
Erscheinungsdatum	2022-08-04
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.903557
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Idoneità igienico-sanitaria delle superfici e degli strumenti nella ristorazione collettiva: analisi di un’esperienza nella realtà ospedaliera.

Quaranta, Gianluigi / Bruno, Stefania / Turnaturi, Cinzia / Bresa, Benedetto / Mandolini, Alessandro / Boldrin, Antonella / Berloco, Filippo / Cambieri, Andrea / Laurenti, Patrizia

Igiene e sanita pubblica

2020 Band 76, Heft 2, Seite(n) 119–129

Abstract: The Authors present the results of an experience carried out in a University General Hospital, for the assessment of the sanitation of surfaces and instruments in the context of hospital refection. A specific procedure has been quarterly implemented in ... ...

Titelübersetzung	The assessment of the sanitation of surfaces and instruments in the context of hospital refection.
Abstract	The Authors present the results of an experience carried out in a University General Hospital, for the assessment of the sanitation of surfaces and instruments in the context of hospital refection. A specific procedure has been quarterly implemented in order to verify the correct execution of the sanitization procedures. In the time-period September 2016 - March 2020 Petri dishes and tampons were used in order to determine the following microbiological parameters and indicators: total bacterial load at 30 degrees C, Coliforms, Listeria monocytogenes, Salmonella spp, Staphylococcus aureus, Escherichia coli and mycetic load. Only 7 out of 82 sanitized surfaces (8.5% of the total) were found to be not complying, only for total bacterial load at 30 degrees C, mycetic load and Coliforms. The systematic application of this procedure and the results of the survey conducted, comforting as a whole, confirm the attention reserved to the hygienic level of surfaces, tools, equipment and utensils, in the context of the centralized catering service of the hospital, in which the Health Department, sharing with the UOC Hospital Hygiene the specific hygienic procedure, has always been at the forefront of the proposal of interventions, considering the increased susceptibility and vulnerability of the hospitalized patients.
Mesh-Begriff(e)	Hospitals, University/standards ; Humans ; Hygiene/standards ; Listeria monocytogenes ; Sanitation/standards
Sprache	Italienisch
Erscheinungsdatum	2020-09-02
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ZDB-ID	3031485-9
ISSN	0019-1639
ISSN	0019-1639
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Enhancement of Vaccination Attitude and Flu Vaccination Coverage among Pregnant Women Attending Birthing Preparation Course.

Bruno, Stefania / Carducci, Brigida / Quaranta, Gianluigi / Beccia, Viria / Di Pilla, Andrea / La Milia, Daniele Ignazio / Di Pumpo, Marcello / Carini, Elettra / Masini, Lucia / Tamburrini, Enrica / Spadea, Antonietta / Damiani, Gianfranco / Lanzone, Antonio / Laurenti, Patrizia

Vaccines

2021 Band 9, Heft 2

Abstract: Most vaccinations are recommended within the 15th month of life, in order to reduce risks and to protect children from the initial stages of their lives. A vaccination training session was carried out during the birthing preparation course, aimed at ... ...

Abstract	Most vaccinations are recommended within the 15th month of life, in order to reduce risks and to protect children from the initial stages of their lives. A vaccination training session was carried out during the birthing preparation course, aimed at increasing the attitude toward vaccination in maternal-child age. A questionnaire on vaccination awareness was administered before and after the training session and on-site flu vaccination was offered to women and their companions. The percentage of participants who consider the preparatory course a useful tool to obtain information about vaccines increases significantly from 30.34% at pre-intervention to 64.56% at post-intervention (
Sprache	Englisch
Erscheinungsdatum	2021-02-21
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines9020183
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: A management model for Hospital Hygiene Unit: evidence-based proactive surveillance of potential environmental sources of infection in order to prevent patient's risk.

Quaranta, Gianluigi / DI Pumpo, Marcello / LA Milia, Daniele Ignazio / Wachocka, Malgorzata / Pattavina, Fabio / Vincenti, Sara / Damiani, Gianfranco / Laurenti, Patrizia / Moscato, Umberto / Bruno, Stefania / Boninti, Federica / Tuti, Federica / Sezzatini, Romina

Journal of preventive medicine and hygiene

2021 Band 61, Heft 4, Seite(n) E628–E635

Abstract: Introduction: The aim of this study is to describe a proactive surveillance system of food, water and environmental surfaces, in order to avoid Healthcare-Associated Infections (HAIs) from hospital environment.: Methods: It is a retrospective ... ...

Abstract	Introduction: The aim of this study is to describe a proactive surveillance system of food, water and environmental surfaces, in order to avoid Healthcare-Associated Infections (HAIs) from hospital environment. Methods: It is a retrospective descriptive study. The surveillance system consists of two integrated phases: pre-analytic and post-analytic. The activities are distinguished in ordinary control activities, performed after scheduled and shared surveys, and compliance activities, performed when it is necessary to establish the adequacy of the destination use, for example opening a new ward. Results: A total of 1,470 Samples were collected and 539 Reports were generated across the five-year study period. Water for human consumption procedure: a statistically significant trend was found only in the total number of Samples collected (p < 0.001). Legionella spp. infection water risk procedure: all Samples and Reports, with the exception of Compliance Report Samples, showed a statistically significant trend (p < 0.001). Pseudomonas aeruginosa water risk procedure: only Ordinary Reports and Compliance Report Samples trend were statistically significant (p = 0.002 and p = 0.028 respectively). Effectiveness of surface sanitization procedure: no trend was statistically significant (p < 0.05). Hospital catering and food surfaces procedure: Samples and Reports yearly number was constant, no trend analysis was performed. HAIs prevalence was never over 5% in the hospital under study. Conclusions: This surveillance system of water, food and environmental surfaces represents an innovative way of approaching hospital safety for patients and personnel because it overcomes the limitations due to a classic approach limited to a laboratory analytic phase only, according to the best available scientific evidence.
Mesh-Begriff(e)	Cross Infection/epidemiology ; Cross Infection/prevention & control ; Hospitals ; Humans ; Hygiene ; Legionella/isolation & purification ; Legionellosis/prevention & control ; Pseudomonas Infections/prevention & control ; Pseudomonas aeruginosa/isolation & purification ; Retrospective Studies ; Water Microbiology
Sprache	Englisch
Erscheinungsdatum	2021-01-14
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ZDB-ID	1102926-2
ISSN	2421-4248 ; 1121-2233
ISSN (online)	2421-4248
ISSN	1121-2233
DOI	10.15167/2421-4248/jpmh2020.61.4.1587
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Idoneità igienico-sanitaria di alimenti e superfici in una mensa ospedaliera: un’esperienza in un Policlinico Universitario.

Quaranta, Gianluigi / Marruco, Roberta / Posteraro, Brunella / Cambieri, Andrea / Berloco, Filippo / Sezzatini, Romina / Boninti, Federica / Turnaturi, Cinzia / Laurenti, Patrizia

Igiene e sanita pubblica

2018 Band 73, Heft 6, Seite(n) 579–593

Abstract: The Authors present the results of a study performed during a time-period of two years, to evaluate the hygienic quality of ready-to-eat foods, prepared and served in a hospital catering service, and the microbiological status of food-contact surfaces. ... ...

Titelübersetzung	Hygienic suitability of food and food-contact surfaces in a hospital canteen: the experience of a University Hospital in Italy.
Abstract	The Authors present the results of a study performed during a time-period of two years, to evaluate the hygienic quality of ready-to-eat foods, prepared and served in a hospital catering service, and the microbiological status of food-contact surfaces. Food hygiene was evaluated using non-pathogenic indicator microorganisms. The study was part of the verification activities that the hospital Health Department considers as a priority in order to guarantee patient safety. Only one of 52 food samples tested was considered unsatisfactory; the examined surfaces were not fully satisfactory in one of four cases. The study results, although encouraging as a whole, especially with respect to the hygienic safety of food prepared and served in the hospital, confirm the need to continuously verify that the appropriate environmental sanitation procedures are applied, even in the case of outsourcing. Considering the increased susceptibility of hospitalized patients, this remains a priority in the hospital where the study was performed.
Mesh-Begriff(e)	Equipment Contamination/statistics & numerical data ; Food Handling/standards ; Food Microbiology/standards ; Food Service, Hospital/standards ; Hospitals, University ; Hygiene/standards ; Italy ; Sanitation/standards
Sprache	Italienisch
Erscheinungsdatum	2018-03-23
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ISSN	0019-1639
ISSN	0019-1639
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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