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  1. Book ; Conference proceedings: New insights in mechanical ventilation

    Quintel, Michael

    recent knowledge, limitations, and doubts

    (Medizinische Klinik, Intensivmedizin und Notfallmedizin ; Band 113, Supplement 1 (Februar 2018))

    2018  

    Event/congress Deutsches Smart Meeting (2017, FrankfurtamMain)
    Author's details guest editors: Prof. Dr. Michael Quintel, Prof. Dr. Luciano Gattinoni
    Series title Medizinische Klinik, Intensivmedizin und Notfallmedizin ; Band 113, Supplement 1 (Februar 2018)
    Collection
    Language English
    Size S30 Seiten, Illustrationen, Diagramme
    Publisher Springer Medizin
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Conference proceedings
    Note "... articles are based on lectures that were given during the last German Smart Meeting in January 2017 in Frankfurt"
    HBZ-ID HT019712058
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: "I feel how you feel": reflections about empathy in the relationship between ICU physicians and relatives.

    Quintel, Michael

    Intensive care medicine

    2017  Volume 43, Issue 11, Page(s) 1723–1724

    MeSH term(s) Emotions ; Empathy ; Humans ; Intensive Care Units ; Physicians
    Language English
    Publishing date 2017-07-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-017-4872-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neue intensivmedizinische Herausforderungen durch Klimawandel und globale Erderwärmung.

    Bein, T / Karagiannidis, C / Gründling, M / Quintel, M

    Der Anaesthesist

    2020  Volume 69, Issue 7, Page(s) 463–469

    Abstract: Background: In the last five decades a continuous increase in the average global temperature has been recorded. Furthermore, natural disasters (e.g. heat waves, severe storms, floods and large forest fires) are becoming more frequent. The impact of ... ...

    Title translation New challenges for intensive care medicine due to climate change and global warming.
    Abstract Background: In the last five decades a continuous increase in the average global temperature has been recorded. Furthermore, natural disasters (e.g. heat waves, severe storms, floods and large forest fires) are becoming more frequent. The impact of global warming and climate change on health involves an increase in respiratory, cardiovascular, renal and cognitive mental diseases. Furthermore, a change in the frequency and patterns of infectious diseases can also be observed in Europe.
    Material and methods: This article presents the most important studies that investigated diseases associated with the climate change, with special reference to those that represent a challenge for intensive care medicine.
    Results: Currently available epidemiological data and statistical extrapolations indicate that diseases resulting from the climate change (acute infection-related respiratory and intestinal diseases, exacerbation of pre-existing pulmonary lesions, heat-related dehydration, cerebral insults and myocardial infarction) are relevant for intensive care medicine. Particular emphasis is placed on a significant increase in acute kidney damage during heat waves. A previously unknown pattern of infectious diseases necessitates new knowledge and targeted management. In some studies, persisting mental impairments were registered during heat waves and natural disasters, e.g. posttraumatic stress disorder.
    Conclusion: Intensive care medicine must be prepared for the challenges due to global warming and climate change. Slow but continuous changes (e.g. rise in temperature) as well as acute changes (e.g. heat waves and natural disasters) will induce an increased need for intensive medical care services (e.g. an increase in the need for renal replacement procedures). Intensive care physicians will need to be familiar with the diagnostics and management of diseases associated with the climate change. An initiative of the specialist societies involved would be welcomed.
    MeSH term(s) Cardiovascular Diseases ; Climate Change ; Communicable Diseases ; Critical Care/trends ; Global Warming ; Humans ; Kidney Diseases ; Lung Diseases ; Mental Health
    Keywords covid19
    Language German
    Publishing date 2020-05-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 260-4
    ISSN 1432-055X ; 0003-2417
    ISSN (online) 1432-055X
    ISSN 0003-2417
    DOI 10.1007/s00101-020-00783-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: New insights in mechanical ventilation.

    Gattinoni, L / Quintel, M

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2017  Volume 113, Issue Suppl 1, Page(s) 1

    MeSH term(s) Respiration, Artificial
    Language English
    Publishing date 2017-11-26
    Publishing country Germany
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-017-0393-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Is mechanical ventilation a cure for ARDS?

    Gattinoni, L / Quintel, M

    Intensive care medicine

    2016  Volume 42, Issue 5, Page(s) 916–917

    MeSH term(s) Humans ; Positive-Pressure Respiration ; Pulmonary Gas Exchange ; Respiration, Artificial/methods ; Respiratory Distress Syndrome, Adult/physiopathology ; Respiratory Distress Syndrome, Adult/therapy ; Tidal Volume
    Language English
    Publishing date 2016-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-016-4266-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Extrakorporale Membranoxygenierung (ECMO) im Erwachsenenalter.

    Meinhardt, J P / Quintel, M

    Intensivmedizin + Notfallmedizin : Organ der Deutschen und der Osterreichischen Gesellschaft fur internistische Intensivmedizin, der Sektion Neurologie der DGIM und der Sektion Intensivmedizin im Berufsverband Deutscher Internisten e.V

    2016  Volume 39, Issue 8, Page(s) 694–706

    Abstract: Despite ongoing discussions, ECMO (extracorporeal membrane oxygenation) has become an important part of treatment options in acute lung injury and ARDS (acute respiratory distress syndrome) even in adults. On the other hand, none of the two RCT ( ... ...

    Title translation Extracorporeal membrane oxygenation (ECMO) in adults.
    Abstract Despite ongoing discussions, ECMO (extracorporeal membrane oxygenation) has become an important part of treatment options in acute lung injury and ARDS (acute respiratory distress syndrome) even in adults. On the other hand, none of the two RCT (randomized controlled trial) studies resulted in reduced letality of the artificial lung therapy when compared to convention treatment. Both authors concluded, that ECMO is not recommended in ARDS. Meanwhile experience with ECMO in adults is extensive in various institutions worldwide, exceeding 1000 patients by the end of 2001. Growing experience and improved technical equipment reduce the rate of technical complications substantially. However, for different reasons ECMO incidence in adults is progressively decreasing in recent years.    Inclusion and exclusion criteria vary among different ECMO centers. Potential reversibility of lung injury and persisting life-threatening gas exchange disorder under maximal conventional therapy are commonly seen as requirements for ECMO therapy. ECMO criteria are Murray lung injury score >3.5 (chest x-ray, PaO
    Keywords covid19
    Language German
    Publishing date 2016-01-02
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 2636018-4
    ISSN 1435-1420 ; 2193-6226 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 1435-1420 ; 2193-6226
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00390-002-0343-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Vergleichende Untersuchung der Neuroleptanalgesie und der Elektrostimulationsanästhesie nach der 'Heidelberger Methode' bei vaginalen und abdominalen Hysterectomien

    Quintel, Michael

    1985  

    Size 123 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 1985 (Nicht f.d. Austausch)
    HBZ-ID HT002912978
    Database Catalogue ZB MED Medicine, Health

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  8. Article: A Potential Role of the Renin-Angiotensin-System for Disturbances of Respiratory Chemosensitivity in Acute Respiratory Distress Syndrome and Severe Acute Respiratory Syndrome.

    Hülsmann, Swen / Khabbazzadeh, Sepideh / Meissner, Konrad / Quintel, Michael

    Frontiers in physiology

    2021  Volume 11, Page(s) 588248

    Abstract: Acute respiratory distress syndrome (ARDS) represents an acute diffuse inflammation of the lungs triggered by different causes, uniformly leading to a noncardiogenic pulmonary edema with inhomogeneous densities in lung X-ray and lung CT scan and acute ... ...

    Abstract Acute respiratory distress syndrome (ARDS) represents an acute diffuse inflammation of the lungs triggered by different causes, uniformly leading to a noncardiogenic pulmonary edema with inhomogeneous densities in lung X-ray and lung CT scan and acute hypoxemia. Edema formation results in "heavy" lungs, inducing loss of compliance and the need to spend more energy to "move" the lungs. Consequently, an ARDS patient, as long as the patient is breathing spontaneously, has an increased respiratory drive to ensure adequate oxygenation and CO
    Language English
    Publishing date 2021-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2020.588248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Hemodynamic profiling by critical care echocardiography could be more accurate than invasive techniques and help identify targets for treatment.

    Schmidt, Stefan / Dieks, Jana-Katharina / Quintel, Michael / Moerer, Onnen

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 7187

    Abstract: In this prospective observational study, non-invasive critical care echocardiography (CCE) was used to obtain quantitative hemodynamic parameters in 107 intensive care unit (ICU) patients; the parameters were then visualized in a novel web graph approach ...

    Abstract In this prospective observational study, non-invasive critical care echocardiography (CCE) was used to obtain quantitative hemodynamic parameters in 107 intensive care unit (ICU) patients; the parameters were then visualized in a novel web graph approach to increase the understanding and impact of CCE abnormalities, as an alternative to thermodilution techniques. Visualizing the CCE hemodynamic data in six-dimensional web graph plots was feasible in almost all ICU patients. In 23.1% of patients, significant tricuspid regurgitation prevented correlation between thermodilution techniques and echocardiographic hemodynamics. Two parameters of longitudinal right ventricular function (TAPSE and S') did not correlate in ICU patients. Clinical surrogate parameters of hemodynamic compromise did not correlate with measured hemodynamics. 26.2% of the patients with mean arterial pressures above 60 mmHg had cardiac indices (CI) below 2.5 L min
    MeSH term(s) Critical Care/methods ; Echocardiography/methods ; Hemodynamics ; Humans ; Tricuspid Valve Insufficiency ; Ventricular Function, Right
    Language English
    Publishing date 2022-05-03
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-11252-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Association of Sex Differences with Mortality and Organ Dysfunction in Patients with Sepsis and Septic Shock.

    Mewes, Caspar / Runzheimer, Julius / Böhnke, Carolin / Büttner, Benedikt / Hinz, José / Quintel, Michael / Mansur, Ashham

    Journal of personalized medicine

    2023  Volume 13, Issue 5

    Abstract: Background: Despite recent advances in the clinical management and understanding of sepsis and septic shock, these complex clinical syndromes continue to have high mortality rates. The effect of sex on these diseases' mortality, clinical presentation ... ...

    Abstract Background: Despite recent advances in the clinical management and understanding of sepsis and septic shock, these complex clinical syndromes continue to have high mortality rates. The effect of sex on these diseases' mortality, clinical presentation and morbidity remains controversial. This study aimed to investigate the association of sex with mortality and organ dysfunction in patients with sepsis and septic shock.
    Methods: Prospectively enrolled patients with clinically defined sepsis and septic shock in three intensive care units at University Medical Center Göttingen, Germany, were investigated. The primary outcomes were 28- and 90-day mortality, while the secondary endpoints included the evaluation of organ dysfunction as measured by clinical scores and laboratory parameters.
    Results: A total of 737 septic patients were enrolled, including 373 in septic shock, 484 males, and 253 females. No significant differences in 28- and 90-day mortality were observed in the cohort. However, men with sepsis had significantly higher SOFA scores, SOFA respiratory and renal subscores, bilirubin and creatinine values, and lower weight-adapted urine outputs, indicating higher organ dysfunction compared to women.
    Conclusions: Our findings revealed notable differences in organ dysfunction between male and female patients, with males exhibiting more pronounced dysfunction across multiple clinical indicators. These results highlight the potential influence of sex on sepsis disease severity and suggest the need for tailored approaches in sepsis management according to patient sex.
    Language English
    Publishing date 2023-05-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13050836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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