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  1. Book ; Thesis: Rolle des TGF-beta Signalweges für die Aufrechterhaltung der Stammzellcharakteristik bei Karzinomstammzellen des Pankreas

    Gafarli, Samra / Rückert, Felix

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Samra Gafarli ; Referent: Herr Prof. Dr. med. Felix Rückert
    Language German
    Size 83 Seiten, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität zu Heidelberg, 2021
    HBZ-ID HT021406044
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2022 E 710 order for loan Magazin

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  2. Book ; Thesis: TGF-? pathway activity and the expression of SPARC and TSP-1 in pancratic versus biliary tract cancers

    Aghamaliyev, Ughur / Rückert, Felix

    2020  

    Institution Universität Heidelberg
    Author's details vorgelegt von Ughur Aghamaliyev ; Referent: Prof. Dr. med. Felix Rueckert
    Language English
    Size 68 Blätter, Diagramme, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021387921
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Analyse des Kurz- und Langzeitergebnisses nach Resektion von intrahepatischen und extrahepatischen cholangiozellulären Karzinomen

    Rahimli, Mirhasan / Rückert, Felix

    2019  

    Title variant Kurzzeitergebnisses
    Institution Universität Heidelberg
    Author's details vorgelegt von Mirhasan Rahimli ; Referent: Prof. Dr. med. Felix Rückert
    Language German
    Size 99 Blätter, Diagramme, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität zu Heidelberg, 2020
    HBZ-ID HT020907988
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 E 535 order for loan Magazin

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  4. Book ; Thesis: Analyse des histologischen Spektrums resezierter Lebermetastasen an der Chirurgischen Klinik der Universitätsmedizin Mannheim

    Zaltenbach, Benjamin / Rückert, Felix

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Benjamin Rouven Zaltenbach ; Referent: Prof. Dr. med. F. Rückert
    Language German
    Size 90 Blätter, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität zu Heidelberg, 2021
    HBZ-ID HT021406043
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2022 E 709 order for loan Magazin

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  5. Book ; Thesis: Bilirubin and PTEN/PI3K/AKT interactions on the proliferative and inflammatory signaling pathways in cholangiocytes

    Wang, Qikun / Rückert, Felix

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Qikun Wang ; Referent: Prof. Dr. med. Felix Rueckert
    Language English
    Size 58 Blätter, Diagramme, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2023
    HBZ-ID HT030626435
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
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  6. Book ; Online ; Thesis: Analyse der neuen ISGLS-Definition der postoperativen Leberblutung (PHH) – Relevanz und Anwendung in der Klinik

    Tesfazgi, Winta [Verfasser] / Rückert, Felix [Akademischer Betreuer]

    2022  

    Author's details Winta Tesfazgi ; Betreuer: Felix Rückert
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  7. Book ; Online ; Thesis: Potential Therapeutic Effect of Human Adipose-Derived Stem Cells on hypoxia in vitro and in vivo

    Zheng, Jiaxing [Verfasser] / Rückert, Felix [Akademischer Betreuer]

    2022  

    Author's details Jiaxing Zheng ; Betreuer: Felix Rückert
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  8. Book ; Online ; Thesis: Einfluss des metabolischen Status und postoperativer Pankreatitiden auf die Entwicklung postoperativer Pankreasfisteln

    Reeg, Alina [Verfasser] / Rückert, Felix [Akademischer Betreuer]

    2021  

    Author's details Alina Christina Reeg ; Betreuer: Felix Rückert
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  9. Article ; Online: Impact of spleen preservation on the incidence of postoperative pancreatic fistula after distal pancreatectomy: Is less more?

    Șandra-Petrescu, Flavius / Tzatzarakis, Emmanouil / Mansour Basha, Mamdouh / Rückert, Felix / Reissfelder, Christoph / Birgin, Emrullah / Rahbari, Nuh N

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

    2022  Volume 22, Issue 7, Page(s) 1013–1019

    Abstract: Background: Postoperative pancreatic fistula (POPF) remains a major complication after distal pancreatectomy (DP) with a significant impact on patients' quality of life. There is limited evidence that preservation of the spleen reduces the risk of POPF. ...

    Abstract Background: Postoperative pancreatic fistula (POPF) remains a major complication after distal pancreatectomy (DP) with a significant impact on patients' quality of life. There is limited evidence that preservation of the spleen reduces the risk of POPF. Therefore, we aimed to investigate the impact of splenectomy on perioperative outcome.
    Methods: Data from patients who underwent DP for malignant and benign disease at our institution between 2004 and 2021 were reviewed. Patients were grouped according to spleen preservation (SP-DP) and splenectomy (DPS). Intraoperative parameters and postoperative outcomes were compared between groups. Univariable and multivariable analyses were used to investigate factors that influence the occurrence of clinically relevant (cr)POPF.
    Results: A total of 199 patients were included, of whom 61 (30.7%) patients underwent SP-DP. Patients who underwent SP-DP had a significantly lower rate of crPOPF (p = 0.022), shorter hospital stay (p = 0.003), and less readmissions (p = 0.012). On multivariate analysis, obesity (OR 2.88, p = 0.021), benign lesions (OR 2.35, p = 0.018), postoperative acute pancreatitis (OR 2.53, p = 0.028), and splenectomy (OR 2.83, p = 0.011) were independent risk factors associated with the onset of crPOPF.
    Discussion: Preservation of the spleen reduces the risk of crPOPF in patients undergoing distal pancreatectomy for benign and malignant disease.
    MeSH term(s) Humans ; Pancreatectomy/adverse effects ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/etiology ; Pancreatic Fistula/prevention & control ; Spleen ; Incidence ; Quality of Life ; Acute Disease ; Pancreatic Neoplasms/pathology ; Retrospective Studies ; Pancreatitis/complications ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control ; Postoperative Complications/etiology
    Language English
    Publishing date 2022-08-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2056680-3
    ISSN 1424-3911 ; 1424-3903
    ISSN (online) 1424-3911
    ISSN 1424-3903
    DOI 10.1016/j.pan.2022.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5553: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Impact of intraoperative margin clearance on survival following pancreatoduodenectomy for pancreatic cancer: a systematic review and meta-analysis.

    Birgin, Emrullah / Rasbach, Erik / Téoule, Patrick / Rückert, Felix / Reissfelder, Christoph / Rahbari, Nuh N

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 22178

    Abstract: The use of intraoperative margin revision to achieve margin clearance in patients undergoing pancreatoduodenectomy for pancreatic cancer is controversial. We performed a systematic review and meta-analysis to summarize the evidence of intraoperative ... ...

    Abstract The use of intraoperative margin revision to achieve margin clearance in patients undergoing pancreatoduodenectomy for pancreatic cancer is controversial. We performed a systematic review and meta-analysis to summarize the evidence of intraoperative margin revisions of the pancreatic neck and its impact on overall survival (OS). Nine studies with 4501 patients were included. Patient cohort was stratified in an R0R0-group (negative margin on frozen and permanent section), R1R0-group (revised positive margin on frozen section which turned negative on permanent section), and R1R1-group (positive margin on frozen and permanent section despite margin revision). OS was higher in the R1R0-group (HR 0.83, 95% CI 0.72-0.96, P = 0.01) compared to the R1R1-group but lower compared to the R0R0-group (HR 1.20; 95% CI 1.05-1.37, P = 0.008), respectively. Subgroup analyses on the use of different margin clearance definitions confirmed an OS benefit in the R1R0-group compared to the R1R1-group (HR 0.81; 95% CI 0.65-0.99, P = 0.04). In conclusion, intraoperative margin clearance of the pancreatic neck margin is associated with improved OS while residual tumor indicates aggressive tumor biology. Consensus definitions on margin terminologies, clearance, and surgical techniques are required.
    MeSH term(s) Biopsy ; Female ; Humans ; Intraoperative Period ; Male ; Margins of Excision ; Neoplasm Grading ; Neoplasm Staging ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/methods ; Prognosis ; Proportional Hazards Models ; Treatment Outcome
    Language English
    Publishing date 2020-12-17
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-79252-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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