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  1. AU="Radloff, R"
  2. AU="Rishi R. Agrawal"
  3. AU="Aldigun, Hazeez"
  4. AU="V. Balaji"
  5. AU="Hanache, Sarah"
  6. AU="Aziz Belkadi"
  7. AU="Weiying, Lu"
  8. AU="Hiroki Ishikawa"
  9. AU=Fischer Lorenz
  10. AU="Hooberman, B H"
  11. AU="Vaid, Nidhi"
  12. AU="Xiao Han"
  13. AU="Stuart G. Tangye"
  14. AU="Yao-Zhong Zhao"
  15. AU="Chern, Chang-Ming"
  16. AU="Floeter, Jens"
  17. AU="Wijnen, Petal"
  18. AU="Saravanamuthu, Pira"
  19. AU="Kalpana Deepa Priya Dorayappan"
  20. AU="Xiao, Hongkui"
  21. AU="Lali, Arvind M"
  22. AU="Kim, Hyojeong"
  23. AU="Nasseri, Saeed"
  24. AU="Kluge"
  25. AU="Bierbaumer, Lisa"
  26. AU="Rashid, Muhammad"
  27. AU="Huang, Chiun-Sheng"
  28. AU="Shevchuk, O O"
  29. AU="Mulvihill, Emily"
  30. AU="Gandhi, Adarsh"
  31. AU="Zhao, Chuanrui"
  32. AU="Shelley Wiart"
  33. AU="Lydia E. Wroblewski" AU="Lydia E. Wroblewski"
  34. AU="Paterson, Ross"
  35. AU="Alexander Marx"
  36. AU="Robinson, Jill"
  37. AU="Mitchell, Adam W M"
  38. AU="Ingham, Jesse R"

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  1. Konferenzbeitrag: Smart Health im Infektionsmanagement. Die Zukunft der evidenz-basierten Infektiologie?

    Radloff, Robert

    2021  , Seite(n) 21ebmPS–2–05

    Veranstaltung/Kongress 22. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin; Who cares? – EbM und Transformation im Gesundheitswesen; sine loco [digital]; Deutsches Netzwerk Evidenzbasierte Medizin e.V.; 2021
    Schlagwörter Medizin, Gesundheit
    Erscheinungsdatum 2021-02-23
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/21ebm059
    Datenquelle German Medical Science

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  2. Konferenzbeitrag: Turning data into cure and ethics first

    Radloff, Robert / Schmitt, Alexander

    2021  , Seite(n) 21ebmSYM–5–01

    Veranstaltung/Kongress 22. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin; Who cares? – EbM und Transformation im Gesundheitswesen; sine loco [digital]; Deutsches Netzwerk Evidenzbasierte Medizin e.V.; 2021
    Schlagwörter Medizin, Gesundheit
    Erscheinungsdatum 2021-02-23
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/21ebm129
    Datenquelle German Medical Science

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  3. Artikel: Opinion evaluation and affiliation.

    RADLOFF, R

    Journal of abnormal and social psychology

    2003  Band 62, Seite(n) 578–585

    Mesh-Begriff(e) Humans ; Psychology, Social
    Sprache Englisch
    Erscheinungsdatum 2003-10-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 3129-x
    ISSN 1939-1846 ; 0096-851X
    ISSN (online) 1939-1846
    ISSN 0096-851X
    DOI 10.1037/h0040412
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Determining the gluonic gravitational form factors of the proton.

    Duran, B / Meziani, Z-E / Joosten, S / Jones, M K / Prasad, S / Peng, C / Armstrong, W / Atac, H / Chudakov, E / Bhatt, H / Bhetuwal, D / Boer, M / Camsonne, A / Chen, J-P / Dalton, M M / Deokar, N / Diefenthaler, M / Dunne, J / El Fassi, L /
    Fuchey, E / Gao, H / Gaskell, D / Hansen, O / Hauenstein, F / Higinbotham, D / Jia, S / Karki, A / Keppel, C / King, P / Ko, H S / Li, X / Li, R / Mack, D / Malace, S / McCaughan, M / McClellan, R E / Michaels, R / Meekins, D / Paolone, Michael / Pentchev, L / Pooser, E / Puckett, A / Radloff, R / Rehfuss, M / Reimer, P E / Riordan, S / Sawatzky, B / Smith, A / Sparveris, N / Szumila-Vance, H / Wood, S / Xie, J / Ye, Z / Yero, C / Zhao, Z

    Nature

    2023  Band 615, Heft 7954, Seite(n) 813–816

    Abstract: The proton is one of the main building blocks of all visible matter in the ... ...

    Abstract The proton is one of the main building blocks of all visible matter in the Universe
    Sprache Englisch
    Erscheinungsdatum 2023-03-29
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-023-05730-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Ultrafast photoinduced dynamics of halogenated cyclopentadienes: observation of geminate charge-transfer complexes in solution.

    Wolf, T J A / Schalk, O / Radloff, R / Wu, G / Lang, P / Stolow, A / Unterreiner, A-N

    Physical chemistry chemical physics : PCCP

    2013  Band 15, Heft 18, Seite(n) 6673–6683

    Abstract: The photoinduced dynamics of the fully halogenated cyclopentadienes C5Cl6 and C5Br6 have been investigated in solution and gas phase by femtosecond time-resolved spectroscopy. Both in solution and in gas phase, homolytic dissociation into a halogen ... ...

    Abstract The photoinduced dynamics of the fully halogenated cyclopentadienes C5Cl6 and C5Br6 have been investigated in solution and gas phase by femtosecond time-resolved spectroscopy. Both in solution and in gas phase, homolytic dissociation into a halogen radical and a C5X5 (X = Cl, Br) radical was observed. In liquid phase, solvent-dependent formation of charge transfer complexes between geminate radicals was observed for the first time. These complexes were found to be surprisingly stable and offered the opportunity to follow the dynamics of specific radical pairs. In the case of C5Cl6 in trichloroethanol, a reaction of the chlorine radical with molecules from the solvent cage was observed.
    Mesh-Begriff(e) Cyclopentanes/chemistry ; Gases/chemistry ; Halogenation ; Photoelectron Spectroscopy ; Quantum Theory ; Solutions/chemistry ; Ultraviolet Rays
    Chemische Substanzen Cyclopentanes ; Gases ; Solutions
    Sprache Englisch
    Erscheinungsdatum 2013-05-14
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/c3cp44295k
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The Thiamine diphosphate dependent Enzyme Engineering Database: a tool for the systematic analysis of sequence and structure relations.

    Widmann, Michael / Radloff, Robert / Pleiss, Jürgen

    BMC biochemistry

    2010  Band 11, Seite(n) 9

    Abstract: Background: Thiamine diphosphate (ThDP)-dependent enzymes form a vast and diverse class of proteins, catalyzing a wide variety of enzymatic reactions including the formation or cleavage of carbon-sulfur, carbon-oxygen, carbon-nitrogen, and especially ... ...

    Abstract Background: Thiamine diphosphate (ThDP)-dependent enzymes form a vast and diverse class of proteins, catalyzing a wide variety of enzymatic reactions including the formation or cleavage of carbon-sulfur, carbon-oxygen, carbon-nitrogen, and especially carbon-carbon bonds. Although very diverse in sequence and domain organisation, they share two common protein domains, the pyrophosphate (PP) and the pyrimidine (PYR) domain. For the comprehensive and systematic comparison of protein sequences and structures the Thiamine diphosphate (ThDP)-dependent Enzyme Engineering Database (TEED) was established.
    Description: The TEED http://www.teed.uni-stuttgart.de contains 12048 sequence entries which were assigned to 9443 different proteins and 379 structure entries. Proteins were assigned to 8 different superfamilies and 63 homologous protein families. For each family, the TEED offers multisequence alignments, phylogenetic trees, and family-specific HMM profiles. The conserved pyrophosphate (PP) and pyrimidine (PYR) domains have been annotated, which allows the analysis of sequence similarities for a broad variety of proteins. Human ThDP-dependent enzymes are known to be involved in many diseases. 20 different proteins and over 40 single nucleotide polymorphisms (SNPs) of human ThDP-dependent enzymes were identified in the TEED.
    Conclusions: The online accessible version of the TEED has been designed to serve as a navigation and analysis tool for the large and diverse family of ThDP-dependent enzymes.
    Mesh-Begriff(e) Amino Acid Sequence ; Databases, Protein ; Enzymes/chemistry ; Enzymes/genetics ; Humans ; Molecular Sequence Data ; Protein Engineering ; Protein Structure, Tertiary ; Sequence Alignment ; Sequence Analysis, Protein ; Thiamine Pyrophosphate/chemistry ; Thiamine Pyrophosphate/metabolism
    Chemische Substanzen Enzymes ; Thiamine Pyrophosphate (Q57971654Y)
    Sprache Englisch
    Erscheinungsdatum 2010-02-01
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041216-2
    ISSN 1471-2091 ; 1471-2091
    ISSN (online) 1471-2091
    ISSN 1471-2091
    DOI 10.1186/1471-2091-11-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Energiebewusste Bauleitplanung

    Radloff, Ralf

    1996  , Seite(n) 46–55

    Schlagwörter Energieeinsparung ; Umweltgerechtes Bauen ; Umweltvertraeglichkeit ; Bauleitplanung ; Bebauungsplan ; Klimaschutz ; Kommunalebene ; Baugesetzbuch ; Waermeschutzverordnung ; Staedtebau ; Energieverbrauch ; Waermedaemmung ; Waermeversorgung
    Sprache Deutsch
    Dokumenttyp Artikel
    Datenquelle OPAC und UmweltLIteraturDATenbank (ULIDAT) des Umweltbundesamtes (UBA)

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  8. Artikel: The reversion of temperature-sensitive mutants of encephalomyocarditis virus upon serial passage in three continuous cell lines.

    Radloff, R J

    The Journal of general virology

    1985  Band 66 Pt 2, Seite(n) 367–371

    Abstract: Several temperature-sensitive mutants of encephalomyocarditis virus were serially passed numerous times in HeLa, L929 and BHK-21 cells. The reversion of most of the mutants occurred most rapidly in BHK-21 cells and least rapidly in HeLa cells. ...

    Abstract Several temperature-sensitive mutants of encephalomyocarditis virus were serially passed numerous times in HeLa, L929 and BHK-21 cells. The reversion of most of the mutants occurred most rapidly in BHK-21 cells and least rapidly in HeLa cells.
    Mesh-Begriff(e) Animals ; Cell Line ; Cricetinae ; Encephalomyocarditis virus/genetics ; HeLa Cells/microbiology ; Humans ; Kidney ; Mesocricetus ; Mutation ; Species Specificity ; Temperature ; Virus Cultivation
    Sprache Englisch
    Erscheinungsdatum 1985-02
    Erscheinungsland England
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 219316-4
    ISSN 1465-2099 ; 0022-1317
    ISSN (online) 1465-2099
    ISSN 0022-1317
    DOI 10.1099/0022-1317-66-2-367
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Novel CYP2B6 enzyme variants in a Rwandese population: functional characterization and assessment of in silico prediction tools.

    Radloff, Robert / Gras, Alain / Zanger, Ulrich M / Masquelier, Cécile / Arumugam, Karthik / Karasi, Jean-Claude / Arendt, Vic / Seguin-Devaux, Carole / Klein, Kathrin

    Human mutation

    2013  Band 34, Heft 5, Seite(n) 725–734

    Abstract: Cytochrome P450 CYP2B6 is a highly polymorphic enzyme that metabolizes numerous drugs, pesticides, and environmental toxins. Sequence analysis of a Rwandese population identified eight functionally uncharacterized nonsynonymous variants c.329G>T (p.G110V) ...

    Abstract Cytochrome P450 CYP2B6 is a highly polymorphic enzyme that metabolizes numerous drugs, pesticides, and environmental toxins. Sequence analysis of a Rwandese population identified eight functionally uncharacterized nonsynonymous variants c.329G>T (p.G110V), c.341T>C (p.I114T), c.444G>T (p.E148D), c.548T>G (p.V183G), c.637T>C (p.F213L), c.758G>A (p.R253H), c.835G>C (p.A279P), and c.1459C>A (p.R487S), and five novel alleles termed CYP2B6*33 to CYP2B6*37 were assigned. Recombinant expression in COS-1 cells and functional characterization using the antidepressant bupropion and the antiretroviral efavirenz (EFV) as substrates demonstrated complete or almost complete loss-of-function for variants p.G110V, p.I114T, p.V183G, and p.F213L, whereas p.E148D, p.R253H, p.A279P, and p.R487S variants were functional. The data were used to assess the predictive power of eight online available functional prediction programs for amino-acid changes. Although none of the programs correctly predicted the functionality of all variants, substrate docking simulation analyses indicated similar conformational changes by all four deleterious mutations within the enzyme's active site, thus explaining lack of enzymatic function for both substrates. Because low-activity alleles of CYP2B6 are associated with impaired EFV metabolism and adverse drug response, these results are of potential utility for personalized treatment strategies in HIV/AIDS therapy.
    Mesh-Begriff(e) Aryl Hydrocarbon Hydroxylases/chemistry ; Aryl Hydrocarbon Hydroxylases/genetics ; Blotting, Western ; Cytochrome P-450 CYP2B6 ; Genetics, Population ; Haplotypes ; Humans ; Molecular Dynamics Simulation ; Mutation ; Oxidoreductases, N-Demethylating/chemistry ; Oxidoreductases, N-Demethylating/genetics ; Polymorphism, Single Nucleotide ; Rwanda
    Chemische Substanzen Aryl Hydrocarbon Hydroxylases (EC 1.14.14.1) ; CYP2B6 protein, human (EC 1.14.14.1) ; Cytochrome P-450 CYP2B6 (EC 1.14.14.1) ; Oxidoreductases, N-Demethylating (EC 1.5.-)
    Sprache Englisch
    Erscheinungsdatum 2013-05
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1126646-6
    ISSN 1098-1004 ; 1059-7794
    ISSN (online) 1098-1004
    ISSN 1059-7794
    DOI 10.1002/humu.22295
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering over a Range of Spin-0 Nuclei.

    Adhikari, D / Albataineh, H / Androic, D / Aniol, K / Armstrong, D S / Averett, T / Ayerbe Gayoso, C / Barcus, S / Bellini, V / Beminiwattha, R S / Benesch, J F / Bhatt, H / Bhatta Pathak, D / Bhetuwal, D / Blaikie, B / Boyd, J / Campagna, Q / Camsonne, A / Cates, G D /
    Chen, Y / Clarke, C / Cornejo, J C / Covrig Dusa, S / Dalton, M M / Datta, P / Deshpande, A / Dutta, D / Feldman, C / Fuchey, E / Gal, C / Gaskell, D / Gautam, T / Gericke, M / Ghosh, C / Halilovic, I / Hansen, J-O / Hauenstein, F / Henry, W / Horowitz, C J / Jantzi, C / Jian, S / Johnston, S / Jones, D C / Karki, B / Kakkar, S / Katugampola, S / Keppel, C E / King, P M / King, D E / Knauss, M / Kumar, K S / Kutz, T / Lashley-Colthirst, N / Leverick, G / Liu, H / Liyange, N / Malace, S / Mammei, J / Mammei, R / McCaughan, M / McNulty, D / Meekins, D / Metts, C / Michaels, R / Mihovilovic, M / Mondal, M M / Napolitano, J / Nikolaev, D / Rashad, M N H / Owen, V / Palatchi, C / Pan, J / Pandey, B / Park, S / Paschke, K D / Petrusky, M / Pitt, M L / Premathilake, S / Puckett, A J R / Quinn, B / Radloff, R / Rahman, S / Rathnayake, A / Reed, B T / Reimer, P E / Richards, R / Riordan, S / Roblin, Y / Seeds, S / Shahinyan, A / Souder, P A / Tang, L / Thiel, M / Tian, Y / Urciuoli, G M / Wertz, E W / Wojtsekhowski, B / Xiong, W / Yale, B / Ye, T / Zec, A / Zhang, W / Zhang, J / Zheng, X

    Physical review letters

    2022  Band 128, Heft 14, Seite(n) 142501

    Abstract: We report precision determinations of the beam-normal single spin asymmetries (A_{n}) in the elastic scattering of 0.95 and 2.18 GeV electrons off ^{12}C, ^{40}Ca, ^{48}Ca, and ^{208}Pb at very forward angles where the most detailed theoretical ... ...

    Abstract We report precision determinations of the beam-normal single spin asymmetries (A_{n}) in the elastic scattering of 0.95 and 2.18 GeV electrons off ^{12}C, ^{40}Ca, ^{48}Ca, and ^{208}Pb at very forward angles where the most detailed theoretical calculations have been performed. The first measurements of A_{n} for ^{40}Ca and ^{48}Ca are found to be similar to that of ^{12}C, consistent with expectations and thus demonstrating the validity of theoretical calculations for nuclei with Z≤20. We also report A_{n} for ^{208}Pb at two new momentum transfers (Q^{2}) extending the previous measurement. Our new data confirm the surprising result previously reported, with all three data points showing significant disagreement with the results from the Z≤20 nuclei. These data confirm our basic understanding of the underlying dynamics that govern A_{n} for nuclei containing ≲50 nucleons, but point to the need for further investigation to understand the unusual A_{n} behavior discovered for scattering off ^{208}Pb.
    Sprache Englisch
    Erscheinungsdatum 2022-04-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.128.142501
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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