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  1. Article ; Online: En guide till koagulationsanalys med viskoelastiska instrument.

    Ulfsdotter Nilsson, Caroline / Radulovic, Vladimir / Jeppsson, Anders / Strandberg, Karin

    Lakartidningen

    2023  Volume 120

    Abstract: Viscoelastic hemostasis analyses (VHA) are a complement in the evaluation of hemostasis in patients with major bleeding. The analysis measures viscoelastic changes in whole blood and the results give an overview of several components of hemostasis. VHA ... ...

    Title translation Analysis with viscoelastic hemostatic assays - a guide.
    Abstract Viscoelastic hemostasis analyses (VHA) are a complement in the evaluation of hemostasis in patients with major bleeding. The analysis measures viscoelastic changes in whole blood and the results give an overview of several components of hemostasis. VHA can be used to optimize fibrinogen levels, platelet and plasma substitution. The main clinical evidence supporting this strategy is in trauma, obstetric bleeding, heart and liver surgery, where algorithms based on VHA results facilitate individualized therapy. VHA measurement is of limited value to exclude treatment with anticoagulants and platelet inhibitors. Quality control aspects are also more cumbersome since whole blood with limited sustainability is used. Newer, more automated versions of the instruments have increased the reproducibility. The main advantage of VHA is the fast turn-around time and their role in guiding treatment in an emergency situation with bleeding.
    MeSH term(s) Humans ; Hemostatics/therapeutic use ; Reproducibility of Results ; Thrombelastography/methods ; Hemostasis ; Blood Coagulation Tests ; Hemorrhage/therapy ; Blood Coagulation Disorders
    Chemical Substances Hemostatics
    Language Swedish
    Publishing date 2023-04-06
    Publishing country Sweden
    Document type English Abstract ; Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
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  2. Article: Radiation Response of Large-Area 4H-SiC Schottky Barrier Diodes.

    Bernat, Robert / Knežević, Tihomir / Radulović, Vladimir / Snoj, Luka / Makino, Takahiro / Ohshima, Takeshi / Capan, Ivana

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 6

    Abstract: We report on the effects of large-area 4H-SiC Schottky barrier diodes on the radiation response to ionizing particles. Two different diode areas were compared: 1 mm × 1 mm and 5 mm × 5 mm. ...

    Abstract We report on the effects of large-area 4H-SiC Schottky barrier diodes on the radiation response to ionizing particles. Two different diode areas were compared: 1 mm × 1 mm and 5 mm × 5 mm.
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16062202
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  3. Article ; Online: Hemostatic effects of a dextran-based priming solution for cardiopulmonary bypass: A secondary analysis of a randomized clinical trial.

    Barbu, Mikael / Kolsrud, Oscar / Radulovic, Vladimir / Dellgren, Göran / Björk, Kerstin / Thorén, Anders / Pivodic, Aldina / Ricksten, Sven-Erik / Jeppsson, Anders

    Thrombosis research

    2023  Volume 223, Page(s) 139–145

    Abstract: Introduction: Intravascular fluids administered to patients may influence hemostasis. In patients undergoing cardiac surgery with cardiopulmonary bypass, the heart-lung machine is primed with 1300 ml of fluid. We assessed postoperative coagulation and ... ...

    Abstract Introduction: Intravascular fluids administered to patients may influence hemostasis. In patients undergoing cardiac surgery with cardiopulmonary bypass, the heart-lung machine is primed with 1300 ml of fluid. We assessed postoperative coagulation and platelet function in patients randomized to two different priming solutions, one colloid-based (dextran 40) and one crystalloid-based.
    Materials and methods: Eighty-four elective cardiac surgery patients were randomized to either a dextran-based prime or Ringer's acetate with added mannitol. Blood samples were collected before, and 2 and 24 h after cardiopulmonary bypass. Coagulation was assessed by standard coagulation tests and rotational thromboelastometry. Platelet function was assessed with impedance aggregometry. Bleeding volumes and transfusion requirements were recorded.
    Results: Comparing the groups 2 h after bypass, the dextran group showed lower hemoglobin concentration, hematocrit, platelet count, and fibrinogen concentration, and higher INR and aPTT, as well as longer clot formation time (+41 ± 21 % vs. +8 ± 18 %, p < 0.001) and a larger reduction in fibrinogen-dependent clot strength (-37 ± 12 % vs. -7 ± 20 %, p < 0.001). Adenosine diphosphate-dependent platelet activation was reduced in the dextran group but not in the crystalloid group 2 h after bypass (-14 ± 29 % vs. -1 ± 41 %, p = 0.041). No significant between-group differences in hemostatic variables remained after 24 h, and no significant differences in perioperative bleeding volumes, re-explorations for bleeding, or transfusion rates were observed.
    Conclusions: Compared to a crystalloid solution, a dextran-based prime had measurable negative impact on hemostatic variables but no detectable increase in bleeding volume or transfusion requirements in cardiac surgery patients.
    MeSH term(s) Humans ; Hemostatics ; Cardiopulmonary Bypass ; Dextrans ; Hemostasis ; Fibrinogen ; Crystalloid Solutions
    Chemical Substances Hemostatics ; Dextrans ; Fibrinogen (9001-32-5) ; Crystalloid Solutions
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2023.01.028
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 863: Show issues Location:
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  4. Article ; Online: Maternal and neonatal outcomes in carriers of haemophilia A and B: A Swedish Medical Birth Register study.

    Olsson, Anna / Radulovic, Vladimir / Wennerholm, Ulla-Britt

    Haemophilia : the official journal of the World Federation of Hemophilia

    2019  Volume 26, Issue 1, Page(s) e14–e17

    MeSH term(s) Adult ; Female ; Hemophilia A/complications ; Hemophilia B/complications ; Humans ; Infant, Newborn ; Male ; Pregnancy ; Pregnancy Complications, Hematologic/physiopathology ; Pregnancy Outcome ; Sweden
    Language English
    Publishing date 2019-11-19
    Publishing country England
    Document type Letter
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.13884
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    Zs.MO 450: Show issues

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  5. Book ; Online: Distinguishing the EH1 and S1 defects in n-type 4H-SiC by Laplace DLTS

    Knežević, Tihomir / Brodar, Tomislav / Radulović, Vladimir / Snoj, Luka / Makino, Takahiro / Capan, Ivana

    2022  

    Abstract: We report on the low-energy electron and fast neutron irradiated 4H-SiC studied by deep-level transient spectroscopy (DLTS) and Laplace DLTS. Irradiations introduced two defects, Ec-0.4eV and Ec-0.7eV. They were previously assigned to carbon interstitial ...

    Abstract We report on the low-energy electron and fast neutron irradiated 4H-SiC studied by deep-level transient spectroscopy (DLTS) and Laplace DLTS. Irradiations introduced two defects, Ec-0.4eV and Ec-0.7eV. They were previously assigned to carbon interstitial (Ci) labeled as EH1/3 and silicon-vacancy (VSi) labeled as S1/2, for the low-energy electron and fast neutron irradiation, respectively. This work demonstrates how Laplace DLTS can be used as a useful tool for distinguishing the EH1 and S1 defects. We show that EH1 consists of a single emission line arising from the Ci(h), while S1 has two emission lines arising from the VSi(h) and VSi(k) lattice sites.
    Keywords Condensed Matter - Materials Science
    Publishing date 2022-08-24
    Publishing country us
    Document type Book ; Online
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  6. Article: 4H-SiC Schottky Barrier Diodes for Efficient Thermal Neutron Detection.

    Bernat, Robert / Bakrač, Luka / Radulović, Vladimir / Snoj, Luka / Makino, Takahiro / Ohshima, Takeshi / Pastuović, Željko / Capan, Ivana

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 17

    Abstract: In this work, we present the improved efficiency of 4H-SiC Schottky barrier diodes-based detectors equipped with the thermal neutron converters. This is achieved by optimizing the thermal neutron converter thicknesses. Simulations of the optimal ... ...

    Abstract In this work, we present the improved efficiency of 4H-SiC Schottky barrier diodes-based detectors equipped with the thermal neutron converters. This is achieved by optimizing the thermal neutron converter thicknesses. Simulations of the optimal thickness of thermal neutron converters have been performed using two Monte Carlo codes (Monte Carlo N-Particle Transport Code and Stopping and Range of Ions in Matter). We have used
    Language English
    Publishing date 2021-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14175105
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  7. Article: Sterilization of polypropylene membranes of facepiece respirators by ionizing radiation

    Pirker, Luka / Krajnc, Anja Pogačnik / Malec, Jan / Radulović, Vladimir / Gradišek, Anton / Jelen, Andreja / Remškar, Maja / Mekjavić, Igor B / Kovač, Janez / Mozetič, Miran / Snoj, Luka

    Journal of membrane science. 2021 Feb. 01, v. 619

    2021  

    Abstract: Ionizing radiation has been identified as an option for sterilization of disposable filtering facepiece respirators in situations where the production of the respirators cannot keep up with demand. Gamma radiation and high energy electrons penetrate ... ...

    Abstract Ionizing radiation has been identified as an option for sterilization of disposable filtering facepiece respirators in situations where the production of the respirators cannot keep up with demand. Gamma radiation and high energy electrons penetrate deeply into the material and can be used to sterilize large batches of masks within a short time period. In relation to reports that sterilization by ionizing radiation reduces filtration efficiency of polypropylene membrane filters on account of static charge loss, we have demonstrated that both gamma and electron beam irradiation can be used for sterilization, provided that the respirators are recharged afterwards.
    Keywords energy ; filtration ; gamma radiation ; irradiation ; polypropylenes
    Language English
    Dates of publication 2021-0201
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 194516-6
    ISSN 0376-7388
    ISSN 0376-7388
    DOI 10.1016/j.memsci.2020.118756
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    Z 78/706: Show issues

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  8. Article ; Online: The European Nuclear Experimental Educational Platform – ENEEP

    Radulović Vladimir / Jazbec Anže / Snoj Luka / Haščik Ján / Vrban Branislav / Čerba Štefan / Lüley Jakub / Osusky Filip / Sklenka Ľubomír / Miglierini Marcel / Novák Ondřej / Böck Helmuth / Cagnazzo Marcella / Villa Mario / Czifrus Szabolcs / Tormási Attila

    EPJ Web of Conferences, Vol 253, p

    Progress, Prospects and Remote Education Capabilities

    2021  Volume 10002

    Abstract: The European Nuclear Experimental Educational Platform – ENEEP is currently being established by five European educational and research organizations in the framework of a Horizon 2020 project, initiated in 2019. The ENEEP partner institutions are the ... ...

    Abstract The European Nuclear Experimental Educational Platform – ENEEP is currently being established by five European educational and research organizations in the framework of a Horizon 2020 project, initiated in 2019. The ENEEP partner institutions are the Jožef Stefan Institute (JSI, Slovenia), the Slovak University of Technology in Bratislava (STU, Slovak Republic), the Czech Technical University in Prague (CTU, Czech Republic), Technische Universität Wien (TU Wien, Austria) and the Budapest University of Technology and Economics (BME, Hungary). ENEEP is intended as an open educational platform, offering experimental hands-on education activities at the ENEEP partner facilities. ENEEP education activities will be offered in different formats (group and individual) and are targeted at university students at all educational levels and young professionals in the nuclear field. This paper gives an overview of the ENEEP project activities and the progress achieved thus far, highlighting the experimental capabilities which will be offered. In the first implementation phase, ENEEP will be based on a comprehensive set of experiments comprising the basics in Reactor Physics and Nuclear Engineering curricula, as well as more specific experiments focusing on particular aspects – investigated phenomena, types and working principles of detectors, etc. Subsequently, novel education activities will be introduced and implemented in ENEEP, following scientific development in nuclear science and technology and nuclear instrumentation detectors, stemming from research activities. Attention will be devoted to the development and optimization of remote education capabilities at the ENEEP partner institutions, of particular relevance during the current Covid-19 pandemic, which is responsible for major changes in education activities worldwide.
    Keywords experimental education activities ; nuclear science and technology ; remote capabilities ; Physics ; QC1-999
    Subject code 020
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
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  9. Article ; Online: Validation of absolute axial neutron flux distribution calculations with MCNP with 197Au(n,γ)198Au reaction rate distribution measurements at the JSI TRIGA Mark II reactor.

    Radulović, Vladimir / Štancar, Žiga / Snoj, Luka / Trkov, Andrej

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2014  Volume 84, Page(s) 57–65

    Abstract: The calculation of axial neutron flux distributions with the MCNP code at the JSI TRIGA Mark II reactor has been validated with experimental measurements of the (197)Au(n,γ)(198)Au reaction rate. The calculated absolute reaction rate values, scaled ... ...

    Abstract The calculation of axial neutron flux distributions with the MCNP code at the JSI TRIGA Mark II reactor has been validated with experimental measurements of the (197)Au(n,γ)(198)Au reaction rate. The calculated absolute reaction rate values, scaled according to the reactor power and corrected for the flux redistribution effect, are in good agreement with the experimental results. The effect of different cross-section libraries on the calculations has been investigated and shown to be minor.
    Language English
    Publishing date 2014-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2013.11.027
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    Ue I Zs.279: Show issues Location:
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  10. Article: Sterilization of polypropylene membranes of facepiece respirators by ionizing radiation.

    Pirker, Luka / Krajnc, Anja Pogačnik / Malec, Jan / Radulović, Vladimir / Gradišek, Anton / Jelen, Andreja / Remškar, Maja / Mekjavić, Igor B / Kovač, Janez / Mozetič, Miran / Snoj, Luka

    Journal of membrane science

    2020  Volume 619, Page(s) 118756

    Abstract: Ionizing radiation has been identified as an option for sterilization of disposable filtering facepiece respirators in situations where the production of the respirators cannot keep up with demand. Gamma radiation and high energy electrons penetrate ... ...

    Abstract Ionizing radiation has been identified as an option for sterilization of disposable filtering facepiece respirators in situations where the production of the respirators cannot keep up with demand. Gamma radiation and high energy electrons penetrate deeply into the material and can be used to sterilize large batches of masks within a short time period. In relation to reports that sterilization by ionizing radiation reduces filtration efficiency of polypropylene membrane filters on account of static charge loss, we have demonstrated that both gamma and electron beam irradiation can be used for sterilization, provided that the respirators are recharged afterwards.
    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 194516-6
    ISSN 0376-7388
    ISSN 0376-7388
    DOI 10.1016/j.memsci.2020.118756
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3272: Show issues Location:
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