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  1. Article ; Online: Modified Subtraction Coronary CT Angiography with a Two-Breathhold Technique: Image Quality and Diagnostic Accuracy in Patients with Coronary Calcifications.

    Guo, Weifeng / Tripathi, Pratik / Yang, Shan / Qian, Juying / Rai, Bimal / Zeng, Mengsu

    Korean journal of radiology

    2019  Volume 20, Issue 7, Page(s) 1146–1155

    Abstract: Objective: To evaluate a modified subtraction coronary computed tomography angiography (CCTA) technique with a two-breathhold approach in terms of image quality and stenosis grading of calcified coronary segments and in the detection of significant ... ...

    Abstract Objective: To evaluate a modified subtraction coronary computed tomography angiography (CCTA) technique with a two-breathhold approach in terms of image quality and stenosis grading of calcified coronary segments and in the detection of significant coronary stenosis in segments with severe calcification.
    Materials and methods: The institutional board approved this study, and all subjects provided written consent. A total of 128 patients were recruited into this trial, of which 32 underwent subtraction CCTA scans and invasive coronary angiography (ICA). The average Agatston score was 356 ± 145. In severely calcified coronary segments, the presence of significant (> 50%) stenosis was assessed on both conventional CCTA and subtraction CCTA images, and the results were finally compared with ICA findings as the gold standard.
    Results: For severely calcified segments, the image quality in conventional CCTA significantly improved from 2.51 ± 0.98 to 3.12 ± 0.94 in subtraction CCTA (
    Conclusion: This modified subtraction CCTA method showed lower misregistration and better image quality in patients with limited breathhold capability. In comparison with conventional CCTA, modified subtraction CCTA would allow stenosis regrading and improve the diagnostic accuracy in coronary segments with severe calcification.
    MeSH term(s) Aged ; Aged, 80 and over ; Breath Holding ; Computed Tomography Angiography/methods ; Coronary Angiography/methods ; Coronary Stenosis/diagnosis ; Coronary Stenosis/diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; ROC Curve ; Sensitivity and Specificity ; Severity of Illness Index ; Tomography, X-Ray Computed/methods ; Vascular Calcification/diagnosis ; Vascular Calcification/diagnostic imaging
    Language English
    Publishing date 2019-07-03
    Publishing country Korea (South)
    Document type Evaluation Study ; Journal Article
    ZDB-ID 2046981-0
    ISSN 2005-8330 ; 1229-6929
    ISSN (online) 2005-8330
    ISSN 1229-6929
    DOI 10.3348/kjr.2018.0845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5591: Show issues Location:
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  2. Article ; Online: Primary total knee arthroplasty using constrained condylar knee design for severe deformity and stiffness of knee secondary to post-traumatic arthritis.

    Rai, Saroj / Liu, Xianzhe / Feng, Xiaobo / Rai, Bimal / Tamang, Nira / Wang, Jing / Ye, Shunan / Yang, Shuhua

    Journal of orthopaedic surgery and research

    2018  Volume 13, Issue 1, Page(s) 67

    Abstract: Background: Key to a successful outcome of total knee arthroplasty (TKA) is to attain optimum alignment, adequate balance, and deformity correction. In primary TKA, this can be achieved efficiently by posterior stabilized (PS) design with or without the ...

    Abstract Background: Key to a successful outcome of total knee arthroplasty (TKA) is to attain optimum alignment, adequate balance, and deformity correction. In primary TKA, this can be achieved efficiently by posterior stabilized (PS) design with or without the sub-periosteal release. However, certain circumstances such as post-traumatic arthritis are often associated with severe deformities with a significant bone defect, stiffness, and instability. Such deformities are extremely difficult to balance with soft tissue release only and require additionally constrained prostheses even in primary TKA. In such situation, constrained condylar knee (CCK) design is the ultimate choice. This study primarily aimed to report on clinical outcome, regain of function, and complication of patients who underwent primary CCK-TKA for severe deformity of the knee secondary to post-traumatic arthritis. The secondary aim was to find out the mid-term prostheses survival.
    Methods: Between February 2007 and November 2013, 38 consecutive patients with post-traumatic arthritis of the knee received cemented primary CCK-TKA. Thirty-four patients (21 men and 13 women) who had a minimum of 3 years follow-up were included in this retrospective study. We used Knee Society Score (KSS), Hospital for Special Surgery (HSS) score, and roentgenographic evaluation form to assess the patients. Prostheses survival was assessed using Kaplan-Meier's survival analysis.
    Results: Patients were followed up for an average duration of 6.47 years. KSS knee score improved from 44 points (23-68) pre-operatively to 91 points (76-100) post-operatively [P < 0.001]. The average KSS functional score improved from 49 points (20-75) pre-operatively to 91 points (65-100) post-operatively [P < 0.001]. The average HSS score improved from 51 points (27-83) pre-operatively to 91 points (75-100) post-operatively [P < 0.001]. Similarly, the average ROM improved from 68.09° ± 35.99° (0°-120°) to 113.68° ± 8.90° (100°-130°) post-operatively [P < 0.001]. The average hip-knee-ankle (HKA) angle was 176.88° ± 14.48° (135°-199°) pre-operatively and 180.24° ± 1.77° (175°-184°) post-operatively. Radiolucencies were evident in 13 knees, mostly on the tibial side. Prostheses survival was 94.7% at a mean follow-up of 6.47 years.
    Conclusion: Despite severe deformity, instability, and stiffness at a relatively young age, mid-term follow-up of primary CCK-TKA in post-traumatic arthritis provides satisfactory clinical and functional outcomes with 94.7% prostheses survival. However, it is not without complication.
    MeSH term(s) Adult ; Aged ; Arthroplasty, Replacement, Knee/adverse effects ; Arthroplasty, Replacement, Knee/instrumentation ; Arthroplasty, Replacement, Knee/methods ; Female ; Follow-Up Studies ; Humans ; Joint Deformities, Acquired/diagnostic imaging ; Joint Deformities, Acquired/etiology ; Joint Deformities, Acquired/surgery ; Knee Injuries/complications ; Knee Joint/diagnostic imaging ; Knee Joint/physiopathology ; Knee Joint/surgery ; Knee Prosthesis/adverse effects ; Male ; Middle Aged ; Osteoarthritis, Knee/diagnostic imaging ; Osteoarthritis, Knee/etiology ; Osteoarthritis, Knee/surgery ; Prosthesis Design ; Prosthesis Failure ; Radiography ; Range of Motion, Articular ; Retrospective Studies ; Severity of Illness Index
    Language English
    Publishing date 2018-04-02
    Publishing country England
    Document type Journal Article
    ISSN 1749-799X
    ISSN (online) 1749-799X
    DOI 10.1186/s13018-018-0761-x
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  3. Article ; Online: A Single Bundle Anterior Cruciate Ligament Reconstruction (ACL-R) Using Hamstring Tendon Autograft and Tibialis Anterior Tendon Allograft: A Comparative Study.

    Rai, Saroj / Jin, Sheng-Yang / Rai, Bimal / Tamang, Nira / Huang, Wei / Liu, Xian-Zhe / Meng, Chun-Qing / Wang, Hong

    Current medical science

    2018  Volume 38, Issue 5, Page(s) 818–826

    Abstract: The main purpose of this study was to compare the clinical outcomes of patients undergoing a single bundle anterior cruciate ligament reconstruction (ACL-R) of using quadrupled hamstring (4HT) autografts and two-strand tibialis anterior (2TA) allografts, ...

    Abstract The main purpose of this study was to compare the clinical outcomes of patients undergoing a single bundle anterior cruciate ligament reconstruction (ACL-R) of using quadrupled hamstring (4HT) autografts and two-strand tibialis anterior (2TA) allografts, and to find out the rate of graft failure and possible causes. We hypothesized that there would be no difference in the clinical outcome, and graft failure would be associated with the use of small sized allograft in young active males with high demand of sports activities. We retrospectively evaluated 222 patients (male, n=167, female, n=55) undergoing ACL-R between January 2010 and July 2014. Of 222 patients, 115 were included in the 4HT autograft group and 107 patients in the 2TA allograft group. Inclusion criteria were primary unilateral ACL-R with a minor MCL (<grade II) injury with or without meniscus tear and had at least 2.5 years of follow-up. Subjective evaluation was performed using Tegner-Lysholm score, modified Cincinnati knee score, and IKDC knee form. Anteroposterior laxity was assessed using ADT and Lachman test whereas rotational laxity was assessed using pivot shift test. Similarly, functional assessment was performed using range of motion (ROM), Daniel's one-leg hop test, and overall IKDC score. Clinical outcomes were satisfactory and comparable in both groups with no statistically significant difference in all the respective parameters. No statistically significant difference was observed in graft re-rupture rate. However, most graft failures occurred in young active males with high demand of sports activities, graft size smaller than 8 mm, and use of allograft. An autograft with at least 8 mm diameter should be considered in a young active male with high demand of sports activities to avoid graft failure.<br />
    MeSH term(s) Adolescent ; Adult ; Allografts/transplantation ; Anterior Cruciate Ligament Injuries/physiopathology ; Anterior Cruciate Ligament Injuries/therapy ; Anterior Cruciate Ligament Reconstruction/methods ; Female ; Hamstring Tendons/physiopathology ; Hamstring Tendons/surgery ; Hamstring Tendons/transplantation ; Humans ; Knee/physiopathology ; Knee/surgery ; Male ; Middle Aged ; Quadruplets ; Rupture/physiopathology ; Rupture/surgery ; Tendons/physiopathology ; Tendons/surgery ; Tendons/transplantation ; Transplantation, Autologous ; Young Adult
    Language English
    Publishing date 2018-10-20
    Publishing country China
    Document type Journal Article
    ISSN 2523-899X
    ISSN (online) 2523-899X
    DOI 10.1007/s11596-018-1948-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Structure and vibrations of glutathione studied by vibrational spectroscopy and density functional theory.

    Singh, Gurpreet / Dogra, Sukh Dev / Kaur, Sarvpreet / Tripathi, S K / Prakash, Satya / Rai, Bimal / Saini, G S S

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2015  Volume 149, Page(s) 505–515

    Abstract: The vibrational properties of glutathione have been investigated by infrared absorption and Raman spectroscopic techniques, and density functional theory calculations at the B3LYP/6-31+G(d,p) level. Assignments of all the experimentally observed ... ...

    Abstract The vibrational properties of glutathione have been investigated by infrared absorption and Raman spectroscopic techniques, and density functional theory calculations at the B3LYP/6-31+G(d,p) level. Assignments of all the experimentally observed vibrational bands have been done with the help of simulated vibrational spectra and potential energy distribution calculations of glutathione water cluster, which includes the effect of hydrogen bonding. Optimized molecular parameters of energy minimized structure have been compared with the available experimental values. Calculated molecular parameters of glutathione-water cluster match well with the experimental values. Some of the calculated molecular parameters and vibrational frequencies of vapor phase glutathione-water cluster suggest participation of some atoms of glutathione in hydrogen bonding. Experimentally observed UV-Visible absorption spectrum of glutathione has also been reported. Observed band at 203 nm has been assigned to electronic transitions calculated with time dependent density functional theory.
    MeSH term(s) Electrons ; Glutathione/chemistry ; Models, Molecular ; Molecular Conformation ; Quantum Theory ; Spectrophotometry, Ultraviolet ; Spectroscopy, Fourier Transform Infrared ; Spectrum Analysis, Raman ; Vibration
    Chemical Substances Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2015
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2015.04.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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    924/340: Show issues

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  5. Article ; Online: Vibrational and electronic spectroscopic studies of melatonin.

    Singh, Gurpreet / Abbas, J M / Dogra, Sukh Dev / Sachdeva, Ritika / Rai, Bimal / Tripathi, S K / Prakash, Satya / Sathe, Vasant / Saini, G S S

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2014  Volume 118, Page(s) 73–81

    Abstract: We report the infrared absorption and Raman spectra of melatonin recorded with 488 and 632.8 nm excitations in 3600-2700 and 1700-70 cm(-1) regions. Further, we optimized molecular structure of the three conformers of melatonin within density functional ... ...

    Abstract We report the infrared absorption and Raman spectra of melatonin recorded with 488 and 632.8 nm excitations in 3600-2700 and 1700-70 cm(-1) regions. Further, we optimized molecular structure of the three conformers of melatonin within density functional theory calculations. Vibrational frequencies of all three conformers have also been calculated. Observed vibrational bands have been assigned to different vibrational motions of the molecules on the basis of potential energy distribution calculations and calculated vibrational frequencies. Observed band positions match well with the calculated values after scaling except NH stretching mode frequencies. It is found that the observed and calculated frequencies mismatch of NH stretching is due to intermolecular interactions between melatonin molecules.
    MeSH term(s) Electrons ; Melatonin/chemistry ; Molecular Conformation ; Spectrophotometry, Infrared ; Spectrophotometry, Ultraviolet ; Spectrum Analysis, Raman ; Vibration
    Chemical Substances Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2014-01-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2013.08.077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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