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  1. Article ; Online: Frequency and reliability of histologic subtype classification in invasive and in situ melanoma treated with Mohs micrographic surgery.

    Stull, Carolyn M / Nugent, Shannon T / Raj, Leela K / Sobanko, Joseph F / Shin, Thuzar M / Etzkorn, Jeremy R / Higgins, Harold W / Giordano, Cerrene N / McMurray, Stacy L / Walker, Joanna L / Miller, Christopher J

    Journal of the American Academy of Dermatology

    2023  Volume 88, Issue 5, Page(s) 1211–1214

    MeSH term(s) Humans ; Mohs Surgery ; Reproducibility of Results ; Melanoma/surgery ; Melanoma/pathology ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology ; Neoplasm Recurrence, Local/surgery
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Using Integra for Reconstruction of Facial Defects after Mohs Micrographic Surgery.

    Bascone, Corey M / Deitermann, Annika / Lin, Stephanie K / McGraw, J Reed / Raj, Leela K / Nugent, Shannon T / Wang, Leo / Broach, Robyn B / Miller, Christopher J / Kovach, Stephen J

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 12, Page(s) e5474

    Abstract: Background: We aimed to identify how Integra bilayer wound matrix has expanded facial reconstruction options after Mohs surgery due to its reliability in both single- and dual-stage reconstruction.: Methods: A retrospective review of patients ... ...

    Abstract Background: We aimed to identify how Integra bilayer wound matrix has expanded facial reconstruction options after Mohs surgery due to its reliability in both single- and dual-stage reconstruction.
    Methods: A retrospective review of patients undergoing Mohs surgery and alloplastic facial reconstruction with Integra between 2012 and 2022 was performed. Patients who underwent single-stage reconstruction and dual-stage reconstruction with skin graft with at least 90 days of follow-up were included.
    Results: One hundred thirty patients with a median age of 76 years were included. Basal cell carcinoma was the most common malignancy (39%). One hundred forty-two lesions were treated and reconstructed same-day with Integra. Lesions most commonly involved the nose (34%) and forehead (22%). The mean postoperative defect size was 26.9 cm
    Conclusions: Integra is a reliable outpatient reconstructive option for facial Mohs defects that can increase the threshold for autologous tissue harvesting and successfully reconstruct large defects of 26.6 cm
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Perianal and anal skin cancers treated with Mohs micrographic surgery and interdisciplinary care: Local recurrence rates and patient-reported outcomes.

    Nugent, Shannon T / Raj, Leela K / Aarons, Cary B / Saur, Nicole M / Kovach, Stephen J / Fischer, John P / Etzkorn, Jeremy R / Shin, Thuzar M / Giordano, Cerrene N / Higgins, H William / Walker, Joanna L / Miller, Christopher J

    Journal of the American Academy of Dermatology

    2023  Volume 89, Issue 6, Page(s) 1283–1285

    MeSH term(s) Humans ; Mohs Surgery ; Skin Neoplasms/surgery ; Skin ; Anus Neoplasms/surgery ; Patient Reported Outcome Measures ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies
    Language English
    Publishing date 2023-08-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.07.1034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A retrospective case series of Mohs micrographic surgery and interdisciplinary management of female genital skin cancers: Local recurrence rates and patient-reported outcomes.

    Nugent, Shannon T / Raj, Leela K / Latif, Nawar A / Cory, Lori / Tanyi, Janos L / Kovach, Stephen J / Fischer, John P / Fosnot, Joshua / Lin, Ines C / Etzkorn, Jeremy R / Shin, Thuzar M / Giordano, Cerrene N / Higgins, H William / Walker, Joanna L / Miller, Christopher J

    Journal of the American Academy of Dermatology

    2023  Volume 89, Issue 2, Page(s) 301–308

    Abstract: Background: Conventional excision of female genital skin cancers has high rates of local recurrence and morbidity. Few publications describe local recurrence rates (LRRs) and patient-reported outcomes (PROs) after Mohs micrographic surgery (MMS) for ... ...

    Abstract Background: Conventional excision of female genital skin cancers has high rates of local recurrence and morbidity. Few publications describe local recurrence rates (LRRs) and patient-reported outcomes (PROs) after Mohs micrographic surgery (MMS) for female genital skin cancers.
    Objective: To evaluate LRRs, PROs, and interdisciplinary care after MMS for female genital skin cancers.
    Methods: A retrospective case series was conducted of female genital skin cancers treated with MMS between 2006 and 2021 at an academic center. The primary outcome was local recurrence. Secondary outcomes were PROs and details of interdisciplinary care.
    Results: Sixty skin cancers in 57 patients were treated with MMS. Common diagnoses included squamous cell cancer (n = 26), basal cell cancer (n = 12), and extramammary Paget disease (n = 11). Three local recurrences were detected with a mean follow-up of 61.1 months (median: 48.8 months). Thirty-one patients completed the PROs survey. Most patients were satisfied with MMS (71.0%, 22/31) and reported no urinary incontinence (93.5%, 29/31). Eight patients were sexually active at follow-up and 75.0% (6/8) experienced no sexual dysfunction. Most cases involved interdisciplinary collaboration 71.7% (43/60).
    Limitations: Limitations include the retrospective single-center design, heterogeneous cohort, and lack of preoperative function data.
    Conclusions: Incorporating MMS into interdisciplinary teams may help achieve low LRRs and satisfactory function after genital skin cancer surgery.
    MeSH term(s) Humans ; Female ; Mohs Surgery ; Retrospective Studies ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/surgery ; Skin Neoplasms/surgery ; Genitalia, Female/surgery
    Language English
    Publishing date 2023-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.02.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interdisciplinary Management of Extramammary Paget's Disease Using Mohs Micrographic Surgery With Frozen Section Cytokeratin-7 Immunostains.

    Bittar, Julie M / Bittar, Peter G / Nugent, Shannon T / Raj, Leela K / Neal, Donald E / Dany, Mohammed / Wan, Marilyn T / Sharkey, John / Etzkorn, Jeremy R / Sobanko, Joseph F / Shin, Thuzar M / Kovach, Stephen / Kovell, Robert C / Latif, Nawar / Miller, Christopher J

    Urology

    2022  Volume 166, Page(s) 164–169

    Abstract: Objective: To describe local recurrence rates and patient-reported outcomes when Mohs micrographic surgery with cytokeratin-7 immunostains (MMS-CK7) is included in the interdisciplinary management of extramammary Paget's disease (EMPD) METHODS: A ... ...

    Abstract Objective: To describe local recurrence rates and patient-reported outcomes when Mohs micrographic surgery with cytokeratin-7 immunostains (MMS-CK7) is included in the interdisciplinary management of extramammary Paget's disease (EMPD) METHODS: A retrospective study was conducted of EMPD treated with MMS-CK7 as part of an interdisciplinary team at an academic medical center between 2009 and 2016. Local recurrence rates and patient-reported outcomes were determined by record review and patient surveys.
    Results: Twenty tumors in 19 patients were treated using MMS-CK7. After MMS-CK7 defined clear microscopic margins, 75% (15/20) of tumors underwent excision or reconstruction by a surgical colleague. Internal malignancy screening was performed by multiple specialties in 17 patients, with 1 associated malignancy of prostate cancer detected. No local recurrence was detected with a mean follow-up of 75.2 months. Most patients were satisfied with appearance (18/19, 95%) and function (16/19, 84%) after surgery.
    Conclusion: Interdisciplinary teams that include MMS-CK7 can treat EMPD with low local recurrence rates, high patient satisfaction, and thorough internal malignancy screening.
    MeSH term(s) Frozen Sections ; Humans ; Keratin-7 ; Male ; Margins of Excision ; Mohs Surgery ; Neoplasm Recurrence, Local/pathology ; Paget Disease, Extramammary/diagnosis ; Paget Disease, Extramammary/surgery ; Retrospective Studies
    Chemical Substances Keratin-7
    Language English
    Publishing date 2022-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2022.04.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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