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  1. Article ; Online: Prevalence Patterns of Body Contouring Procedures Among Injectable Glucagon-Like Peptide-1 Receptor Agonist Users.

    Toms, John A / O'Neill, Elizabeth / Wiegmann, Aaron L / Adepoju, Jubril / Raj, Mamtha S

    Aesthetic surgery journal

    2024  

    Abstract: Background: The introduction of injectable glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic and Wegovy has transformed weight loss in plastic surgery patients, often leading to excess skin and soft tissue amendable to body contouring ... ...

    Abstract Background: The introduction of injectable glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic and Wegovy has transformed weight loss in plastic surgery patients, often leading to excess skin and soft tissue amendable to body contouring procedures.
    Objectives: This project aims to examine the relationship between injectable GLP-1 receptor agonist use and the growing need for body contouring surgeries, focusing on trunk and extremity procedures.
    Methods: A retrospective analysis was conducted using the PearlDiver database, examining prescription data for Ozempic, Wegovy, and liraglutide, and correlating these with body contouring procedures across 30 U.S. states from 2011-2022. Multimodal statistics were used to compare surgery rates and assess dosage and time interval patterns among GLP-1 receptor agonist users and non-users.
    Results: Significant correlations between GLP-1 receptor agonist use (881 Ozempic, 59 Wegovy, and 4,655 liraglutide users) and increased body contouring surgeries were found. Ozempic showed weak correlations with brachioplasty (r = 0.23) and panniculectomy (r = 0.21), and Wegovy with breast procedures (r = 0.28), while liraglutide showed consistent correlations across surgeries. Time to surgery varied from 87 days (Wegovy) to 1,018 days (liraglutide), with higher surgery rates among users (p < 0.01) and dose-related differences, especially in Ozempic and Wegovy users.
    Conclusions: This study demonstrates a dose-dependent link between the use of GLP-1 receptor agonists and an increase in subsequent aesthetic body contouring surgeries, highlighting the need for surgeons to adapt to the merging of medicinal body transformation and aesthetic plastic surgery.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjae085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Abdominal Wall Reconstruction After Extirpation of a 140-Pound Primary Ovarian Mucinous Adenocarcinoma.

    Raj, Mamtha S / Pittala, Karthik / Wallace, Sean J / Wojcik, Randolph

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35542

    Abstract: Ovarian cancer is a feared diagnosis for women and clinicians alike. Ovarian mucinous adenocarcinoma is a unique subset of ovarian cancer. As a primary tumor, massive ovarian masses, and more specifically mucinous adenocarcinomas, have been infrequently ... ...

    Abstract Ovarian cancer is a feared diagnosis for women and clinicians alike. Ovarian mucinous adenocarcinoma is a unique subset of ovarian cancer. As a primary tumor, massive ovarian masses, and more specifically mucinous adenocarcinomas, have been infrequently reported in the medical literature. Team approaches to massive tumor extirpations are essential, as patients often require the expertise of various subspecialists including, but not limited to, gynecologic-oncologists, general surgeons, and plastic and reconstructive surgeons. Here we present a case of a 71-year-old woman with a massive, incapacitating pelvic mass, later found to be a primary ovarian mucinous adenocarcinoma. Once medically optimized, a multi-service team approach was utilized for tumor extirpation and abdominal wall reconstruction. Involved surgical services included Gynecologic-Oncology, General Surgery, and Plastic and Reconstructive Surgery. Exploratory laparotomy for tumor extirpation, hysterectomy, bilateral salpingo-oophorectomy, omentectomy, peritoneal stripping, bilateral inguinal lymphadenectomy, and appendectomy was performed. Extensively thin, devascularized, and attenuated abdominal wall fascia that was adherent to the tumor was removed. The abdominal wall defect was reconstructed and reinforced with inlay and overlays of biologic monofilament mesh. Inverted-T of the vertical and horizontal skin components was performed in a tailor-tacking fashion, assuring the maintenance and protection of the abdominal skin flap vascularity through utilizing the Huger Zones of perfusion. Pathology revealed a stage IA grade 2 mucinous adenocarcinoma of the ovary without evidence of metastasis. No adjuvant therapies were required. The tumor's weight was 140 pounds, and its dimensions were 63 x 41 x 40 cm. It is our hope that presenting this experience will raise awareness of this spectrum of diseases and allow for earlier diagnoses and treatments, as well as exemplify the virtues of a team-based approach in the successful extirpation and subsequent reconstruction of the abdominal wall and skin.
    Language English
    Publishing date 2023-02-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Delayed Thoracodorsal Artery Perforator Free Flap for Calcaneal Degloving Injury Reconstruction.

    Huff, Mallorie L / Mansour, Ahmed M / Raj, Mamtha S / Allen, Robert J / Wallace, Sean J

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 3, Page(s) e4880

    Abstract: The thoracodorsal artery perforator (TDAP) flap has a long vascular pedicle that is ideal for lower extremity reconstruction, but it generally relies on the presence of a dominant septocutaneous perforator vessel. Surgical delay optimizes flap survival ... ...

    Abstract The thoracodorsal artery perforator (TDAP) flap has a long vascular pedicle that is ideal for lower extremity reconstruction, but it generally relies on the presence of a dominant septocutaneous perforator vessel. Surgical delay optimizes flap survival by creating relative ischemia to augment perforator vessels. In this report, we describe the use of a delayed free TDAP flap in the setting of an absent dominant perforator vessel for the reconstruction of a calcaneal degloving injury. A 22-year-old actively smoking patient with a body mass index of 33.5 presented with a nonhealing left heel wound with overlying necrotic changes after traumatic degloving injury. The entire weight-bearing portion of the calcaneal fat pad and the flanking regions were debrided. The TDAP flap was elevated, revealing three small thoracodorsal artery perforators. Given that a dominant perforator was absent, the flap was surgically delayed. Free-tissue transfer occurred 8 days later. This operation was conducted entirely in left lateral decubitus with simultaneous wound preparation and flap harvest. The flap was elevated on two perforators to elongate the pedicle's length and inset to cover exposed calcaneus and pad the heel. Six months postoperatively, the patient is doing well without flap compromise or ulceration. The TDAP flap is a versatile microsurgical tool, and surgical delay extends the utility of this flap when a dominant septocutaneous perforator is unavailable. Recipient site debridement may occur simultaneously with the TDAP delay procedure. Importantly, only one position is required for flap elevation, microsurgical anastomosis, and insetting, thus obviating intraoperative repositioning.
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An unusual cause of cervical kyphosis.

    Raj, Mamtha S / Schwab, Joseph H

    The spine journal : official journal of the North American Spine Society

    2017  Volume 17, Issue 2, Page(s) e7–e9

    Abstract: Background context: Acute fixed cervical kyphosis may be a rare presentation of conversion disorder, psychogenic dystonia, and potentially as a side effect from typical antipsychotic drugs. Haldol has been associated with acute dystonic reactions. In ... ...

    Abstract Background context: Acute fixed cervical kyphosis may be a rare presentation of conversion disorder, psychogenic dystonia, and potentially as a side effect from typical antipsychotic drugs. Haldol has been associated with acute dystonic reactions. In some cases, rigid deformities ensue. We are reporting a case of a fixed cervical kyphosis after the use of Haldol.
    Purpose: To present a case of a potential acute dystonic reaction temporally associated with Haldol ingestion leading to fixed cervical kyphosis.
    Study design: This is a case report.
    Methods: A patient diagnosed with bipolar disorder presented to the emergency room several times with severe neck pain and stiffness. The neck appeared fixed in flexion with extensive osteophyte formation over a 3-month period.
    Results: The patient's condition was resolved by a posterior-anterior-posterior surgical approach. It corrected the patient's cervical curvature from 88° to 5°.
    Conclusions: Acute dystonic reactions have the potential to apply enough pressure on bone to cause rapid osteophyte formation.
    MeSH term(s) Adult ; Antipsychotic Agents/adverse effects ; Antipsychotic Agents/therapeutic use ; Bipolar Disorder/drug therapy ; Cervical Vertebrae/diagnostic imaging ; Female ; Haloperidol/adverse effects ; Haloperidol/therapeutic use ; Humans ; Kyphosis/diagnosis ; Kyphosis/etiology ; Kyphosis/surgery
    Chemical Substances Antipsychotic Agents ; Haloperidol (J6292F8L3D)
    Language English
    Publishing date 2017-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2037072-6
    ISSN 1878-1632 ; 1529-9430
    ISSN (online) 1878-1632
    ISSN 1529-9430
    DOI 10.1016/j.spinee.2016.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Lower Extremity Soft Tissue Reconstruction Review Article.

    Mansour, Ahmed M / Jacobs, Aaron / Raj, Mamtha S / Lee, Frank G / Terrasse, Weston / Wallace, Sean J / Miller, Nathan F

    The Orthopedic clinics of North America

    2022  Volume 53, Issue 3, Page(s) 287–296

    Abstract: Reconstruction plays a valuable role in the management of lower extremity wounds for limb salvage. The goals of reconstruction are to improve function and quality of life, return to work, and pain reduction while providing a long-lasting durable ... ...

    Abstract Reconstruction plays a valuable role in the management of lower extremity wounds for limb salvage. The goals of reconstruction are to improve function and quality of life, return to work, and pain reduction while providing a long-lasting durable reconstruction. The plastics and reconstructive surgical approach in conjunction with the orthopedic or trauma team, referred often as the "orthoplastic" approach, can yield the best outcomes for patients. The following sections discuss reconstruction principles and techniques that can be applied broadly for lower extremity wounds secondary to trauma, infection, and tumor resection.
    MeSH term(s) Humans ; Limb Salvage/methods ; Lower Extremity/surgery ; Quality of Life ; Reconstructive Surgical Procedures/methods ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-05-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 417389-2
    ISSN 1558-1373 ; 0030-5898
    ISSN (online) 1558-1373
    ISSN 0030-5898
    DOI 10.1016/j.ocl.2022.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Non-surgical Management of Complex Refractory Pyoderma Gangrenosum With Negative Pressure Wound Therapy With Instillation.

    Lee, Frank G / Song, Ethan / Wallace, Sean J / Shaughnessy, Thomas J / Raj, Mamtha / Teixeira, Robert / Miles, Marshall G / Wojcik, Randolph

    Cureus

    2021  Volume 13, Issue 10, Page(s) e18951

    Abstract: Pyoderma gangrenosum (PG) is a rare skin disorder primarily treated with immunosuppression medication. We report a case of a large, chronic PG wound treated with adjunct negative pressure wound therapy with instillation and dwell time (NPWTi-d) using ... ...

    Abstract Pyoderma gangrenosum (PG) is a rare skin disorder primarily treated with immunosuppression medication. We report a case of a large, chronic PG wound treated with adjunct negative pressure wound therapy with instillation and dwell time (NPWTi-d) using nonadherent dressing (Mepitel) and reticular open-cell foam with through holes (ROCF-CC) with positive outcomes. The patient was a 62-year-old female with rheumatoid arthritis, Hashimoto's thyroiditis, lymphedema, and morbid obesity who presented with a 19.5 cm x 13.2 cm x 2.1 cm wound of three years duration on the right posterolateral lower extremity that successfully responded to a multimodality approach of immunosuppression and wound vac therapy. We conclude in our case that NPWTi-d with Mepitel and ROCF-CC enhanced the wound healing process, and we discuss NPWTi-d's potential role and benefit as an adjunctive therapy option for chronic and poorly controlled PG on patients taking concurrent immunosuppression.
    Language English
    Publishing date 2021-10-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.18951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Extrapleural Superficial Solitary Fibrous Tumor on the Posterior Shoulder: A Case Report and Review of the Literature.

    Wallace, Sean J / Teixeira, Robert / Miller, Nathan F / Raj, Mamtha / Sheikh, Hina / Sharma, Rohit

    Eplasty

    2018  Volume 18, Page(s) e31

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2018-10-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2412803-X
    ISSN 1937-5719
    ISSN 1937-5719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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