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Article ; Online: Security and Privacy of Cloud- and IoT-Based Medical Image Diagnosis Using Fuzzy Convolutional Neural Network.

Deepika, J / Rajan, C / Senthil, T

Computational intelligence and neuroscience

2021 Volume 2021, Page(s) 6615411

Abstract: In recent times, security in cloud computing has become a significant part in healthcare services specifically in medical data storage and disease prediction. A large volume of data are produced in the healthcare environment day by day due to the ... ...

Abstract	In recent times, security in cloud computing has become a significant part in healthcare services specifically in medical data storage and disease prediction. A large volume of data are produced in the healthcare environment day by day due to the development in the medical devices. Thus, cloud computing technology is utilised for storing, processing, and handling these large volumes of data in a highly secured manner from various attacks. This paper focuses on disease classification by utilising image processing with secured cloud computing environment using an extended zigzag image encryption scheme possessing a greater tolerance to different data attacks. Secondly, a fuzzy convolutional neural network (FCNN) algorithm is proposed for effective classification of images. The decrypted images are used for classification of cancer levels with different layers of training. After classification, the results are transferred to the concern doctors and patients for further treatment process. Here, the experimental process is carried out by utilising the standard dataset. The results from the experiment concluded that the proposed algorithm shows better performance than the other existing algorithms and can be effectively utilised for the medical image diagnosis.
MeSH term(s)	Cloud Computing ; Computer Security ; Confidentiality ; Humans ; Neural Networks, Computer ; Privacy
Language	English
Publishing date	2021-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5265
ISSN (online)	1687-5273
ISSN	1687-5265
DOI	10.1155/2021/6615411
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Article: The Intercostal Chest Drain-the 'C S' Way…!

Rajan, C S

The Indian journal of surgery

2017 Volume 79, Issue 4, Page(s) 286–287

Language	English
Publishing date	2017-08
Publishing country	India
Document type	Editorial
ZDB-ID	138063-1
ISSN	0972-2068 ; 0019-5650
ISSN	0972-2068 ; 0019-5650
DOI	10.1007/s12262-017-1656-5
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Article: A Novel HM-HD-RFET Biosensor for Label-Free Biomolecule Detection.

Biswas, Arpita / Rajan, Chithraja / Samajdar, Dip Prakash

Journal of electronic materials

2022 Volume 51, Issue 11, Page(s) 6388–6396

Abstract: The mortality of people worldwide caused by COVID-19 has enhanced the research interest to design and develop power-efficient, low-cost, and sensitive biosensors to detect a wide range of biomolecules or foreign particles that can cause severe negative ... ...

Abstract	The mortality of people worldwide caused by COVID-19 has enhanced the research interest to design and develop power-efficient, low-cost, and sensitive biosensors to detect a wide range of biomolecules or foreign particles that can cause severe negative impact on humans. A novel Bio-RFET biosensor with hetero-material (HM) for source/channel and drain regions and hetero-dielectric (HD) is proposed, which acts as an
Language	English
Publishing date	2022-09-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2032868-0
ISSN	1543-186X ; 0361-5235
ISSN (online)	1543-186X
ISSN	0361-5235
DOI	10.1007/s11664-022-09872-5
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Book ; Online: Shaping Political Discourse using multi-source News Summarization

Rajan, Charles / Asnani, Nishit / Singh, Shreya

2023

Abstract: Multi-document summarization is the process of automatically generating a concise summary of multiple documents related to the same topic. This summary can help users quickly understand the key information from a large collection of documents. Multi- ... ...

Abstract	Multi-document summarization is the process of automatically generating a concise summary of multiple documents related to the same topic. This summary can help users quickly understand the key information from a large collection of documents. Multi-document summarization systems are more complex than single-document summarization systems due to the need to identify and combine information from multiple sources. In this paper, we have developed a machine learning model that generates a concise summary of a topic from multiple news documents. The model is designed to be unbiased by sampling its input equally from all the different aspects of the topic, even if the majority of the news sources lean one way.
Keywords	Computer Science - Computation and Language ; Computer Science - Computers and Society ; Computer Science - Information Retrieval ; Computer Science - Machine Learning
Publishing date	2023-12-18
Publishing country	us
Document type	Book ; Online
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Article: C S in Surgery, a Personal Perspective.

Rajan, C S

The Indian journal of surgery

2015 Volume 77, Issue Suppl 2, Page(s) 264–269

Abstract: This is a reflection of a 30-year career of a general surgeon, who has maintained a logbook of all his surgical work. Reading between the lines in this logbook, a number of essential qualities and traits needed for a successful career have been brought ... ...

Abstract	This is a reflection of a 30-year career of a general surgeon, who has maintained a logbook of all his surgical work. Reading between the lines in this logbook, a number of essential qualities and traits needed for a successful career have been brought out. All these have been grouped into a novel way, using the letters "C" and "S" to describe each of them. Success in surgery relate to the tripod of Common Sense, dealing with the Changing Scenario, and having Civic Sensibility. Each component of this tripod is further broken down into several entities, all with the letter "C" and "S," to finally give the benefits of such qualities to the surgeon, each of which also begins with the letters "C" and "S."
Language	English
Publishing date	2015-12
Publishing country	India
Document type	Journal Article
ZDB-ID	138063-1
ISSN	0972-2068 ; 0019-5650
ISSN	0972-2068 ; 0019-5650
DOI	10.1007/s12262-012-0790-3
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Article ; Online: Hepatocellular Carcinoma in the Absence of Cirrhosis in a Child With Inactive Chronic Hepatitis B Infection.

Rajan, Charanya / Chiou, Fang Kuan / Merchant, Khurshid / Phua, Kong Boo

JPGN reports

2021 Volume 2, Issue 4, Page(s) e124

Abstract: Chronic hepatitis B infection has been identified as an important risk factor for developing hepatocellular carcinoma (HCC) especially in the presence of hepatitis and liver cirrhosis. However, here we describe an unusual case of a child with chronic ... ...

Abstract	Chronic hepatitis B infection has been identified as an important risk factor for developing hepatocellular carcinoma (HCC) especially in the presence of hepatitis and liver cirrhosis. However, here we describe an unusual case of a child with chronic hepatitis B infection who developed HCC in the absence of active hepatitis or cirrhosis. This case serves to highlight the importance of regular HCC surveillance for all children with chronic hepatitis B, regardless of presence or absence of hepatitis or cirrhosis.
Language	English
Publishing date	2021-09-23
Publishing country	United States
Document type	Case Reports
ISSN	2691-171X
ISSN (online)	2691-171X
DOI	10.1097/PG9.0000000000000124
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Article ; Online: N-of-1 Trials vs. Usual Care in Children With Hypertension: A Pilot Randomized Clinical Trial.

Samuel, Joyce P / Bell, Cynthia S / Samuels, Joshua A / Rajan, Celin / Walton, Adrienne K / Green, Charles / Tyson, Jon E

American journal of hypertension

2023 Volume 36, Issue 2, Page(s) 126–132

Abstract: Background: Blood pressure (BP) is often inadequately controlled in children treated for hypertension, and personalized (n-of-1) trials show promise for tailoring treatment choices. We assessed whether patients whose treatment choices are informed by an ...

Abstract	Background: Blood pressure (BP) is often inadequately controlled in children treated for hypertension, and personalized (n-of-1) trials show promise for tailoring treatment choices. We assessed whether patients whose treatment choices are informed by an n-of-1 trial have improved BP control compared to usual care. Methods: A randomized clinical trial was conducted in a pediatric hypertension clinic in Houston from April 2018 to September 2020. Hypertensive adolescents and young adults 10-22 years old were randomized 1:1 to a strategy of n-of-1 trial using ambulatory BP monitoring to inform treatment choice or usual care, with treatment selected by physician preference. The primary outcome was the proportion of patients with ambulatory BP control at 6 months in a Bayesian analysis. Results: Among 49 participants (23 randomized to n-of-1 trials and 26 to usual care), mean age was 15.6 years. Using skeptical priors, we found a 69% probability that n-of-1 trials increased BP control at 6 months (Bayesian odds ratio (OR) 1.24 (95% credible interval (CrI) 0.51, 2.97), and 74% probability using neutral informed priors (OR 1.45 (95% CrI 0.48, 4.53)). Systolic BP was reduced in both groups, with a 93% probability of greater reduction in the n-of-1 trial group (mean difference between groups = -3.6 mm Hg (95% CrI -8.3, 1.28). There was no significant difference in side effect experience or caregiver satisfaction. Conclusions: Among hypertensive adolescents and young adults, n-of-1 trials with ambulatory BP monitoring likely increased the probability of BP control. A large trial is needed to assess their use in clinical practice. Clinicaltrials.gov: NCT03461003. Clinical trial registry: ClinicalTrials.gov; NCT03461003.
MeSH term(s)	Adolescent ; Young Adult ; Humans ; Child ; Adult ; Pilot Projects ; Bayes Theorem ; Hypertension/diagnosis ; Hypertension/drug therapy ; Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/pharmacology
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2023-02-10
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	639383-4
ISSN	1941-7225 ; 1879-1905 ; 0895-7061
ISSN (online)	1941-7225 ; 1879-1905
ISSN	0895-7061
DOI	10.1093/ajh/hpac117
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Article ; Online: Clinical profile, referral trends, and real-world application of vibration-controlled transient elastography in children with non-alcoholic fatty liver disease in Singapore.

Chiou, Fang Kuan / Goh, Lynette / Ho, Christopher Wen Wei / Rajan, Charanya / Logarajah, Veena / Ng, Lay Queen / Phua, Kong Boo

JGH open : an open access journal of gastroenterology and hepatology

2023 Volume 8, Issue 1, Page(s) e13020

Abstract: Background and aim: Pediatric non-alcoholic fatty liver disease (NAFLD) is a progressive disorder that is increasing in incidence globally. The study aims to describe the clinical profile and longitudinal outcome, including the utility of vibration- ... ...

Abstract	Background and aim: Pediatric non-alcoholic fatty liver disease (NAFLD) is a progressive disorder that is increasing in incidence globally. The study aims to describe the clinical profile and longitudinal outcome, including the utility of vibration-controlled transient elastography (VCTE), in children with NAFLD at a single tertiary liver unit in Singapore. Methods: Retrospective review of patients aged 0-18 years referred for NAFLD from 2003 to 2020 was conducted. Diagnosis was based on persistent elevation of alanine transaminase ≥2× the upper limit of normal in at-risk patients, and/or radiologic detection of hepatic steatosis, with the exclusion of other etiologies. VCTE-derived liver stiffness measurements (LSMs) ≤7.0 , 7.1-9.0, and ≥9.1 kPa were used to differentiate normal (F0-F1), significant fibrosis (F2), and advanced fibrosis (F3-F4), respectively. Results: The study included 210 patients (72.4% male, mean age 11.6 years). New cases increased from 1.7/1000 referrals in 2003-2008 to 12.7 and 24.5/1000 referrals in 2009-2014 and 2015-2020, respectively. Significant proportion had dyslipidemia (41.4%), impaired glucose tolerance/diabetes (IGT/DM, 26.7%), and hypertension (17.1%). Only 6.2% had resolution of NAFLD after a mean follow-up of 3.7 years. Based on VCTE ( Conclusion: Incidence of pediatric NAFLD has increased dramatically in Singapore. Based on LSM estimation, pediatric NAFLD may be associated with an increased risk of developing advanced fibrosis by late adolescence.
Language	English
Publishing date	2023-12-23
Publishing country	Australia
Document type	Journal Article
ISSN	2397-9070
ISSN (online)	2397-9070
DOI	10.1002/jgh3.13020
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Article ; Online: Mobility based key management technique for multicast security in mobile ad hoc networks.

Madhusudhanan, B / Chitra, S / Rajan, C

TheScientificWorldJournal

2015 Volume 2015, Page(s) 801632

Abstract: In MANET multicasting, forward and backward secrecy result in increased packet drop rate owing to mobility. Frequent rekeying causes large message overhead which increases energy consumption and end-to-end delay. Particularly, the prevailing group key ... ...

Abstract	In MANET multicasting, forward and backward secrecy result in increased packet drop rate owing to mobility. Frequent rekeying causes large message overhead which increases energy consumption and end-to-end delay. Particularly, the prevailing group key management techniques cause frequent mobility and disconnections. So there is a need to design a multicast key management technique to overcome these problems. In this paper, we propose the mobility based key management technique for multicast security in MANET. Initially, the nodes are categorized according to their stability index which is estimated based on the link availability and mobility. A multicast tree is constructed such that for every weak node, there is a strong parent node. A session key-based encryption technique is utilized to transmit a multicast data. The rekeying process is performed periodically by the initiator node. The rekeying interval is fixed depending on the node category so that this technique greatly minimizes the rekeying overhead. By simulation results, we show that our proposed approach reduces the packet drop rate and improves the data confidentiality.
Language	English
Publishing date	2015
Publishing country	United States
Document type	Journal Article
ISSN	1537-744X
ISSN (online)	1537-744X
DOI	10.1155/2015/801632
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Article: A comparison of clinical outcomes between vaccinated and vaccine-naive patients of COVID-19, in four tertiary care hospitals of Kerala, South India.

Balachandran, Sabarish / Moni, Merlin / Sathyapalan, Dipu T / Varghese, Prinoj / Jose, Manoj P / Murugan, Mithun R / Rajan, C / Saboo, Dhanraj / Nair, Sooraj S / Varkey, Reshmi Ann / Balachandran, Parvathy / Menon, Geetha R / Vasudevan, Beena K / Banerjee, Amitava / Janakiram, Chandrasekhar / Menon, Jaideep C

Clinical epidemiology and global health

2022 Volume 13, Page(s) 100971

Abstract: The problem considered: This multi-centric study analyzed data of COVID-19 patients and compared differences in symptomatology, management, and outcomes between vaccinated and vaccine-naive patients.: Methods: All COVID-19 positive individuals ... ...

Abstract	The problem considered: This multi-centric study analyzed data of COVID-19 patients and compared differences in symptomatology, management, and outcomes between vaccinated and vaccine-naive patients. Methods: All COVID-19 positive individuals treated as an in-or out-patient from the 1 Results: The analysis was of 1446 patients after exclusion of 156 with missing data of which males were 57.3% and females 42.7%. 346 were vaccinated; 189 received one dose and 157 both doses. Hospitalization was more in vaccinated (38.2% vs 27.4%); ICU admissions were less in vaccinated (3.5% vs 7.1%). More vaccinated were symptomatic (OR = 1.5); half less likely to be on non-invasive ventilation (OR = 0.5) while vaccine naive patients had 4.21 times the risk of death. Conclusion: Severe infection, duration of hospital stays, need for ventilation and death were significantly less among vaccinated when compared with vaccine naive patients.
Language	English
Publishing date	2022-01-19
Publishing country	India
Document type	Journal Article
ISSN	2452-0918
ISSN	2452-0918
DOI	10.1016/j.cegh.2022.100971
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