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Article ; Online: Gum drop technique with pericardial membrane for treating gingival recession - A case report.

P Rao, Abirami N / Rajaram, Vijayalakshmi / Mahendra, Jaideep / Dave, Pavithra H / Ambalavanan, N / Mahendra, Little

Indian journal of dental research : official publication of Indian Society for Dental Research

2024 Volume 34, Issue 3, Page(s) 320–322

Abstract: Introduction: Gingival recession was treated with gum drop technique (GDT) along with pericardial membrane, advanced platelet rich fibrin (A-PRF) and injectable platelet rich fibrin (i-PRF) in the defect sites for regeneration of soft tissue.: Patient ...

Abstract	Introduction: Gingival recession was treated with gum drop technique (GDT) along with pericardial membrane, advanced platelet rich fibrin (A-PRF) and injectable platelet rich fibrin (i-PRF) in the defect sites for regeneration of soft tissue. Patient concerns: Several 3-4 mm of recession sites in the maxillary right and left canine and premolar region. These sites were selected and divided into two groups: A and B based on the application with A-PRF and pericardium, respectively. Probing pocket depth (PPD), clinical attachment level (CAL), recession height (RH), recession width (RW) and keratinized tissue width (KTW) were assessed. The keratinized tissue width (KTW) was measured as the distance between the marginal gingiva and the mucogingival junction. Treatment: The defects were treated with the GDT following irrigation with i-PRF and followed up for 6 months. Both groups achieved significant root coverage which was stable even after 6 months post operatively. Keratinized tissue showed a 1 mm gain with pericardial membrane.
MeSH term(s)	Humans ; Gingival Recession/surgery ; Pericardium/surgery ; Platelet-Rich Fibrin
Language	English
Publishing date	2024-01-10
Publishing country	India
Document type	Case Reports
ZDB-ID	1354886-4
ISSN	1998-3603 ; 0970-9290
ISSN (online)	1998-3603
ISSN	0970-9290
DOI	10.4103/ijdr.ijdr_109_23
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Article ; Online: Advanced-Platelet Rich Fibrin Assisted Papilla Reconstruction by Modified Beagle’s Technique- A Novel Approach

Rajaram Vijayalakshmi / Ravi Sathyapriya / Prakash Prashanthi / Chellathurai Burnice

Journal of Clinical and Diagnostic Research, Vol 14, Iss 4, Pp ZD07-ZD

2020 Volume 09

Abstract: The loss of key papilla in an unaesthetic zone and the presence of a “black triangle” depicts the requirement for papillary reconstruction. The complete reconstruction of lost papilla is unpredictable; therefore, retention of papilla is very important ... ...

Abstract	The loss of key papilla in an unaesthetic zone and the presence of a “black triangle” depicts the requirement for papillary reconstruction. The complete reconstruction of lost papilla is unpredictable; therefore, retention of papilla is very important for aesthetics. There are many causes for loss of papillae and the establishment of “black triangle” between teeth. However, the most common cause is loss of periodontal support due to plaque-associated lesions. However, abnormaility in tooth shape, improper contours of the prosthetic restorations and traumatic oral hygienic procedures may also impact the interdental papilla. The loss of interdental papilla soft tissue causes difficulties in phonetics, aesthetic appearance and lateral food impaction. This case report deals with a variant method of Beagle’s technique 37-year-old systemically healthy male patient with the chief complaint of black space between the upper front teeth region, causing displeasing smile and food entrapment. Intraoral examination done with periodontal probe revealed the loss of 2 mm of interdental papilla. Patient was treated surgically with Advanced Platelet Rich Fibrin (A-PRF) membrane for papilla reconstruction in the upper anterior aesthetic zone.
Keywords	aesthetics ; black triangle ; interdental papilla ; Medicine ; R
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
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Article ; Online: Advanced Platelet-Rich Fibrin in Periosteal Inversion Technique for Root Coverage: A Case Report.

Chellathurai, Burnice Nalina Kumari / Ganesh, Balaji / Rajaram, Vijayalakshmi

Clinical advances in periodontics

2020 Volume 10, Issue 4, Page(s) 181–185

Abstract: Introduction: The management of gingival recession associated with esthetic concerns and root hypersensitivity is challenging, and its sequelae is based on the assessment of etiological factors and the degree of tissue involvement. Procedures using ... ...

Abstract	Introduction: The management of gingival recession associated with esthetic concerns and root hypersensitivity is challenging, and its sequelae is based on the assessment of etiological factors and the degree of tissue involvement. Procedures using pedicle flaps, free soft tissue grafts, combination of pedicle flaps with grafts, barrier membranes, and the use of platelet concentrates are all effective for this purpose. The use of the third-generation platelet concentrate, advanced platelet-rich fibrin (A-PRF), has evolved as a promising regenerative material for root coverage procedure wherein it acts as a scaffold and also accelerates wound healing due to its dense fibrin meshwork. Case presentation: This case report, discusses treating an isolated maxillary Miller Class I recession in a 25-year-old male patient by a periosteal inversion method along with the A-PRF membrane. A partial thickness flap was reflected; periosteum was inverted; and an A-PRF membrane was placed over the denuded root surface which aided in enhanced regeneration; 100% root coverage was obtained as seen in follow-up visits. Conclusion: The periosteal inversion technique along with an A-PRF membrane seems to be a novel approach in managing an isolated Miller Class I maxillary gingival recession.
MeSH term(s)	Adult ; Esthetics, Dental ; Fibrin ; Gingival Recession/surgery ; Humans ; Male ; Platelet-Rich Fibrin ; Treatment Outcome
Chemical Substances	Fibrin (9001-31-4)
Language	English
Publishing date	2020-08-25
Publishing country	United States
Document type	Case Reports
ZDB-ID	2670204-6
ISSN	2163-0097 ; 2573-8046
ISSN (online)	2163-0097
ISSN	2573-8046
DOI	10.1002/cap.10119
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Article ; Online: Laterally Closed Tunnel Approach with A-PRF for Isolated Miller’s Class II Gingival Recession

Mary Jose Nisha / Nalina Kumari Burnice / Kumar S Ashok / Mahendra Jaideep / Rajaram Vijayalakshmi

Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp ZD05-ZD

A Case Report

2020 Volume 07

Abstract: The displacement of the gingival margin below the level of Cementoenamel Junction (CEJ) is referred to as gingival recession. The main indication to treat isolated gingival recession is to increase soft tissue thickness and stability to facilitate plaque ...

Abstract	The displacement of the gingival margin below the level of Cementoenamel Junction (CEJ) is referred to as gingival recession. The main indication to treat isolated gingival recession is to increase soft tissue thickness and stability to facilitate plaque control, improve the patient aesthetics and prevent further periodontal breakdown. Though various root coverage techniques are available with numerous regenerative materials, autologous material such as Advanced Plasma Rich Fibrin (A-PRF) along with latest approach by Laterally Closed Tunnel (LCT) technique has been used in present case report as a predictable approach for the treatment of isolated gingival recessions.
Keywords	advanced plasma rich fibrin ; periodontal regeneration ; root coverage ; Medicine ; R
Language	English
Publishing date	2020-02-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
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Article ; Online: A Comparison in Patient Comfort Using Conventional Syringe and Needleless Jet Anesthesia Technique in Periodontal Surgery—A Split-Mouth Randomized Clinical Trial

Preethi Shankar / Burnice Nalina Kumari Chellathurai / S. Ashok Kumar / Jaideep Mahendra / Maryam H. Mugri / Mohammed Sayed / Mohammad Almagbol / Mohammed Hussain Dafer Al Wadei / Rajaram Vijayalakshmi / Namasivayam Ambalavanan / A. Thirumal Raj / Shankargouda Patil

Medicina, Vol 58, Iss 278, p

2022 Volume 278

Abstract: Background and Objectives: Periodontal surgery requires local anesthetic coverage to alleviate patient discomfort. Needles and injections can engender feelings of fear and anxiety in individuals. This study aimed to assess the level of comfort and ... ...

Abstract	Background and Objectives: Periodontal surgery requires local anesthetic coverage to alleviate patient discomfort. Needles and injections can engender feelings of fear and anxiety in individuals. This study aimed to assess the level of comfort and anxiety in patients during the administration of local anesthesia using needleless jet anesthesia (JA) when compared to a conventional syringe (CS) in periodontal surgery. Method and Materials: 60 sites were designated for injection in a split-mouth design in 30 subjects who required periodontal surgery. Local anesthesia was administered in two appointments scheduled one week apart using either a JA system or a CS. The Visual Analogue Scale (VAS), Verbal Rating Scale (VRS), and Beck’s anxiety inventory were used to report the pain and anxiety levels while injecting local anesthesia. Statistical analysis of the results was performed using the Shapiro–Wilks test and Paired t-test. Results: Patients reported greater comfort with JA. The VAS and VRS values were statistically significant—( p = 0.003) and ( p = 0.001), respectively. Patients showed fear and were nervous about receiving a local anesthetic using a CS. A few subjects experienced lingering pain with the CS, whereas greater comfort and no lingering soreness were reported post-operatively at the site of JA administration. Conclusions: This study provides the first comprehensive assessment of using JA for periodontal surgical procedures. Lower pain scores were consistently observed with the use of jet injectors. Patients were at ease and reported lesser anxiety and greater comfort with jet injectors, making it ideally suited for providing local anesthesia in periodontal surgery.
Keywords	jet injections ; local anesthesia ; periodontal debridement ; Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Platelet Rich Fibrin in double lateral sliding bridge flap procedure for gingival recession coverage: An original study.

Rajaram, Vijayalakshmi / Thyegarajan, Ramakrishnan / Balachandran, Ashwath / Aari, Geetha / Kanakamedala, Anilkumar

Journal of Indian Society of Periodontology

2016 Volume 19, Issue 6, Page(s) 665–670

Abstract: Background: Gingival recession is a common occurrence in periodontal disease leading to an unaesthetic appearance of the gingiva. The effect of platelet-rich fibrin (PRF), when used along with double lateral sliding bridge flap (DLSBF), remains unknown. ...

Abstract	Background: Gingival recession is a common occurrence in periodontal disease leading to an unaesthetic appearance of the gingiva. The effect of platelet-rich fibrin (PRF), when used along with double lateral sliding bridge flap (DLSBF), remains unknown. The aim of this study is to evaluate the effect of PRF in conjunction with DLSBF for multiple gingival recessions. Materials and methods: Twenty systemically healthy individuals exhibiting Grade II gingival recession on their mandibular central incisors were recruited in this study. These patients were randomly assigned into two groups: DLSBF and PRF + DLSBF. The clinical parameters that were evaluated in this study were gingiva recession height, gingiva recession width, width of keratinized gingiva, clinical attachment level, and probing depth. PRF was procured from the patient's blood at the time of the surgery and used for the procedure. The follow-up was performed at 12 and 24 weeks postsurgery. Results: Statistically significant difference was observed between the clinical parameters at baseline and 12 and 24 weeks within the groups. There was no statistically significant difference, between the groups. Mean root coverage (RC) was 80% ±29.1% in the DLSBF group and 78.8% ±37.6% in the DLSBF + PRF group with no statistically significant difference. Conclusion: From the results obtained in this study, the addition of PRF to DLSBF gives no additional benefits to the clinical parameters measured in RC.
Language	English
Publishing date	2016-02-01
Publishing country	India
Document type	Journal Article
ZDB-ID	2545458-4
ISSN	0975-1580 ; 0972-124X
ISSN (online)	0975-1580
ISSN	0972-124X
DOI	10.4103/0972-124X.164764
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Article: Treatment of gingival recession by coronally advanced flap in conjunction with platelet-rich fibrin or resin-modified glass-ionomer restoration: A clinical study.

Ramireddy, Sudheer / Mahendra, Jaideep / Rajaram, Vijayalakshmi / Ari, Geetha / Kanakamedala, Anil Kumar / Krishnakumar, Dhanadivya

Journal of Indian Society of Periodontology

2017 Volume 22, Issue 1, Page(s) 45–49

Abstract: Aims: The aim of this study is to compare the outcome of coronally advanced flap (CAF) along with the use of platelet-rich fibrin (PRF) versus CAF in conjunction with a resin-modified glass-ionomer cement (RmGIC) for the management of Millers Class I ... ...

Abstract	Aims: The aim of this study is to compare the outcome of coronally advanced flap (CAF) along with the use of platelet-rich fibrin (PRF) versus CAF in conjunction with a resin-modified glass-ionomer cement (RmGIC) for the management of Millers Class I and Class II gingival recession coupled with noncarious cervical lesions (NCCLs). Materials and methods: Single and multiple Miller's Class I and Class II gingival recessions were chosen for the study. Twenty participants with total of 78 sites associated with NCCL bilaterally in the anterior and premolar region of maxilla were selected. Thirty-nine sites were treated with CAF and PRF and the remaining 39 sites were treated with CAF and RmGIC. Clinical parameters such as probing pocket depth, relative gingival recession, relative clinical attachment level, NCCL height, NCCL width, width of keratinized tissue, and keratinized tissue thickness were measured at baseline, 90 Results: Both the groups showed optimal root coverage, with statistical significant difference in thickness of keratinized gingiva in Group I when compared to Group II from baseline to 90 Conclusion: The use of PRF along with CAF showed increased thickness of the keratinized tissue and the utilization of RmGIC resulted in decreased DS. Hence, the combination of CAF and PRF or CAF and RmGIC could provide a better treatment option in the management of gingival recession that is of esthetic concern.
Language	English
Publishing date	2017-10-28
Publishing country	India
Document type	Journal Article
ZDB-ID	2545458-4
ISSN	0975-1580 ; 0972-124X
ISSN (online)	0975-1580
ISSN	0972-124X
DOI	10.4103/jisp.jisp_283_17
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Article ; Online: Use of Collagen Membrane in the Treatment of Periodontal Defects Distal to Mandibular Second Molars Following Surgical Removal of Impacted Mandibular Third Molars

C. Burnice Nalina Kumari / Thiagarajan Ramakrishnan / Pradeep Devadoss / Rajaram Vijayalakshmi / Khalid J. Alzahrani / Mazen A. Almasri / Manea Musa. Al-Ahmari / Hajar Saeed Al Dira / Malath Suhluli / Ashok Kumar Bhati / Zeeshan Heera Ahmad / A. Thirumal Raj / Shilpa Bhandi / Shankargouda Patil

Biology, Vol 10, Iss 1348, p

A Comparative Clinical Study

2021 Volume 1348

Abstract: The study aims to assess the efficacy of using collagen membrane in the treatment of distal periodontal defects of mandibular second molars following the removal of mesioangularly or horizontally impacted mandibular third molars surgically. Forty sites ... ...

Abstract	The study aims to assess the efficacy of using collagen membrane in the treatment of distal periodontal defects of mandibular second molars following the removal of mesioangularly or horizontally impacted mandibular third molars surgically. Forty sites in twenty patients with bilaterally impacted mandibular third molars (mesioangular or horizontal) were considered for the study. In 20 test sites (Group A), after surgical removal of the mandibular third molar, a resorbable collagen membrane barrier was placed on the distal aspect of the mandibular second molar to cover the post-surgical bone defect. In the other control 20 sites (Group B), the same surgical procedure was repeated without placing any membrane barrier. The clinical parameters recorded were Oral Hygiene Index Simplified (OHI-S), Probing pocket depth (PPD), Clinical attachment level (CAL), and radiographic assessment of alveolar bone level (ABL). OHI-S score of most of the patients was observed to be satisfactory. Group A was observed to achieve a statistically significant reduction in PPD, CAL, and ABL gain compared to Group B. The improvements indicated that the use of collagen membrane facilitates early wound stabilization and promotes primary closure of the defect. This recovery is achieved through its unique property to assist fibrinogenesis over osteoconduction. Further longitudinal studies are needed to confirm the present findings.
Keywords	collagen membrane ; extraction ; impacted ; mandibular third molar ; periodontal defect ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article: Protective effect of proanthocyanidins on endotoxin induced experimental periodontitis in rats.

Govindaraj, Jayamathi / Emmadi, Pamela / Deepalakshmi / Rajaram, Vijayalakshmi / Prakash, Geetha / Puvanakrishnan, Rengarajulu

Indian journal of experimental biology

2010 Volume 48, Issue 2, Page(s) 133–142

Abstract: The pathogenesis of periodontitis involves anaerobic oral bacteria as well as the host response to infection and several drugs have been developed which can curtail these deleterious effects. Proanthocyanidin, a novel flavanoid extracted from grape seeds, ...

Abstract	The pathogenesis of periodontitis involves anaerobic oral bacteria as well as the host response to infection and several drugs have been developed which can curtail these deleterious effects. Proanthocyanidin, a novel flavanoid extracted from grape seeds, has been shown to provide a significant therapeutic effect on endotoxin (Escherichia coli) induced experimental periodontitis in rats. In this study, protective action of different doses of proanthocyanidins was investigated in blood by assaying the reactive oxygen species such as hydrogen peroxide, superoxide anion, myeloperoxidase and lipid peroxides, lysosomal enzyme activities such as cathepsin B, cathepsin D, beta-glucuronidase and acid phosphatase, nonenzymatic antioxidants such as ascorbic acid, alpha-tocopherol, ceruloplasmin, reduced glutathione and antioxidant enzymes such as catalase, superoxide dismutase, glutathione peroxidase and glutathione-s-transferase. Experimental periodontitis rats showed a reduction in body weight and body weight gain could be noticed when they were administered proanthocyanidins. The levels of reactive oxygen species and lysosomal enzymes were found to increase whereas antioxidant levels were decreased significantly in experimental periodontitis. Proanthocyanidins at an effective dose of 30 mg/kg body weight, sc, for 30 days effected a decrease in serum reactive oxygen species, lipid peroxides, lysosomal enzymes, acute phase proteins and an increase in antioxidant levels. Histopathological evidence of experimental periodontitis showed cellular infiltration of inflammatory cells while proanthocyanidin treated groups demonstrated only scattered inflammatory cells and blood vessels. Thus, the results showed that dietary supplementation of proanthocyanidin enhanced the host resistance as well as the inhibition of the biological and mechanical irritants involved in the onset of gingivitis and the progression of periodontal disease.
MeSH term(s)	Acute-Phase Proteins/immunology ; Animals ; Antioxidants/metabolism ; Body Weight ; Endotoxins/immunology ; Endotoxins/toxicity ; Escherichia coli/chemistry ; Gingiva/drug effects ; Gingiva/immunology ; Gingiva/pathology ; Lipid Peroxidation ; Lysosomes/enzymology ; Male ; Periodontitis/chemically induced ; Periodontitis/drug therapy ; Periodontitis/immunology ; Proanthocyanidins/therapeutic use ; Rats ; Rats, Wistar ; Reactive Oxygen Species/metabolism
Chemical Substances	Acute-Phase Proteins ; Antioxidants ; Endotoxins ; Proanthocyanidins ; Reactive Oxygen Species
Language	English
Publishing date	2010-02
Publishing country	India
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	416061-7
ISSN	0975-1009 ; 0019-5189
ISSN (online)	0975-1009
ISSN	0019-5189
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