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  1. Article ; Online: Are Doctors Unhealthy? Managing Cardiovascular Risks in Physicians

    Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    2023  

    Abstract: ... Not ... ...

    Abstract Not available
    Keywords Not available ; Medicine ; R
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Creating Health Professionals for the 21st Century

    Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    2023  

    Abstract: ... Not ... ...

    Abstract Not available
    Keywords Not available ; Medicine ; R
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Hypertension Control in India

    Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    Lessons from Jaipur Heart Watch

    2023  

    Abstract: ... Not ... ...

    Abstract Not Available
    Keywords Not Available ; Medicine ; R
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Strategies for Return to Normal Following COVID-19 Pandemic

    Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    2023  

    Abstract: ... Not ... ...

    Abstract Not Available
    Keywords Not Available ; Medicine ; R
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Challenges for Hypertension Control in India

    Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    2023  

    Keywords Medicine ; R
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Artificial Intelligence in Primary Healthcare

    Nishant Gupta / Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    Listening, Learning and Talking Computers

    2023  

    Abstract: ... Not ... ...

    Abstract Not Available
    Keywords Not Available ; Medicine ; R
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: To study demographic profile, risk stratification, and response to treatment in chronic myeloid leukemia patients

    Manish Chandey / Rajandeep Kaur / Rajeev Gupta / Gurinder Mohan

    APIK Journal of Internal Medicine, Vol 12, Iss 1, Pp 40-

    2024  Volume 45

    Abstract: Background: Chronic myeloid leukemia (CML) is the most common leukemia in India. The annual incidence of CML in India was originally reported to be 0.82.2 per 100,000 population. CML is a clonal disorder that is usually easily diagnosed by the ... ...

    Abstract Background: Chronic myeloid leukemia (CML) is the most common leukemia in India. The annual incidence of CML in India was originally reported to be 0.82.2 per 100,000 population. CML is a clonal disorder that is usually easily diagnosed by the Philadelphia chromosome. The approval of tyrosine kinase inhibitors has significantly reduced the mortality rate associated with CML and revolutionized treatment. Materials and Methods: Eighty patients diagnosed with CML were studied. Investigations were done and with European Treatment and Outcome Study (EUTOS) patients were stratified into low- and high-risk group and then treatment with Imatinib was given to all patients and molecular response was evaluated. Results: In the study population, out of 80 patients, 40 were female and 40 were male with M: F is 1:1. Out of total 80 patients', maximum patients (54) were in 31-60 years age group. Our study showed that the most common symptom of presentation is abdominal discomfort followed by fever. Out of total 80 patients, 25 (31.3%) patients had high EUTOS score and 55 (68.8%) patients had low EUTOS score. On 6 months' follow-up, 36.3% patients had complete molecular response, 16.3% patients had major molecular response and 47.5% patients had no molecular response, but on 12 months' follow-up, 71.3% patients had complete molecular response, 16.25% patients had major molecular response, and 12.5% patients had no molecular response. Conclusion: In this observational study, we found a significant correlation between EUTOS score and molecular response at 6 months and 12 months follow-up after Imatinib therapy.
    Keywords chronic myeloid leukemia ; european treatment and outcome study score ; response ; tyrosine kinase inhibitor ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Physical Activity and Cardiovascular Health

    Barkha Gupta / Sonali Sharma / Rajeev Gupta

    RUHS Journal of Health Sciences (2023)

    A Brief Review

    2023  

    Abstract: Focus has shifted from cardiovascular risk factors to cardiovascular health and physical fitness. Epidemiological studies have reported that poor cardiovascular health and low levels of physical fitness and physical inactivity are widespread globally, ... ...

    Abstract Focus has shifted from cardiovascular risk factors to cardiovascular health and physical fitness. Epidemiological studies have reported that poor cardiovascular health and low levels of physical fitness and physical inactivity are widespread globally, including India. Prospective studies have reported an inverse association of cardiovascular health, physical fitness, and physical activity with cardiovascular events and deaths. Physical fitness can be improved by regular physical activity and prospective studies have reported a dose-response effect. Guidelines recommend regular walking (>30 minutes/day, at least 5 days/week) and muscle-strengthening exercises (>15 minutes/day, 2 days/week). Regular exercise leads to improvement of fitness, improved quality of life, reduction in cardiometabolic risks, inflammation, blood pressure, dyslipidemias and obesity indices, better blood rheology, and decreased cardiovascular and all-cause morbidity and mortality. Multisectoral and multifactorial interventions are crucial in this regard and can be at the level of social determinants, populations, and individuals. Interventions include planned urbanization, healthy climate and healthy nutrition using target-oriented interventions. Population level interventions should use informational approaches, behavioral and social approaches, school-based strategies and environmental and policy approaches, while individual level interventions should focus on behavior change for promotion of physical activity. Use of technology is important.
    Keywords Cardiovascular disease ; physical activity ; physical fitness ; Medicine ; R
    Subject code 796
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Sonali Sharma on behalf of Rajasthan University of Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Healthcare worker-based opportunistic screening for familial hypercholesterolemia in a low-resource setting.

    Sonali Sharma / Ashish Khudiwal / Sonal Bhardwaj / Hemant Chaturvedi / Rajeev Gupta

    PLoS ONE, Vol 17, Iss 6, p e

    2022  Volume 0269605

    Abstract: Background & objective Heterozygous familial hypercholesterolemia (FHeH) is important risk factor for premature coronary artery disease (CAD). Strategies for its diagnosis and prevalence have not been well studied in India. We performed healthcare worker- ...

    Abstract Background & objective Heterozygous familial hypercholesterolemia (FHeH) is important risk factor for premature coronary artery disease (CAD). Strategies for its diagnosis and prevalence have not been well studied in India. We performed healthcare worker-based opportunistic screening to assess feasibility for determining its prevalence. Methods A healthcare worker was trained in use of Dutch Lipid Clinic Network (DLCN) criteria for diagnosis of FHeH. Successive eligible individuals (n = 3000 of 3450 screened) presenting to biochemistry laboratories of two hospitals for blood lipid measurements were evaluated for FHeH. Cascade screening or genetic studies were not performed. Descriptive statistics are reported. Results We included 2549 participants (men 1870, women 679) not on statin therapy. Health worker screened 25-30 individuals/day in 6-10 minutes each. The mean age was 46.2±11y. Variables of DLCN criteria were more in women vs men: family history 51.1 vs 35.6%, past CAD 48.2 vs 20.1%, arcus cornealis 1.1 vs 0.3%, tendon xanthoma 0.3 vs 0.1%, and LDL cholesterol 190-249 mg/dl in 8.5 vs 2.4%, 250-329 mg/dl in 0.7 vs 0% and ≥330 mg/dl in 0.3 vs 0% (p<0.01). Definite FHeH (DLCN score >8) was in 15 (0.59%, frequency 1:170) and probable FHeH (score 6-8) in 87 (3.4%, frequency 1:29). The prevalence was significantly greater in women, age <50y and in those with hypertension, diabetes and known CAD. Conclusions Healthcare worker-led opportunistic screening for diagnosis of FHeH using DLCN criteria is feasible in low-resource settings. The results show significant prevalence of clinically detected definite and probable FHeH in the population studied.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Challenges in management and prevention of ischemic heart disease in low socioeconomic status people in LLMICs

    Rajeev Gupta / Salim Yusuf

    BMC Medicine, Vol 17, Iss 1, Pp 1-

    2019  Volume 11

    Abstract: Abstract Background Cardiovascular diseases, principally ischemic heart disease (IHD), are the most important cause of death and disability in the majority of low- and lower-middle-income countries (LLMICs). In these countries, IHD mortality rates are ... ...

    Abstract Abstract Background Cardiovascular diseases, principally ischemic heart disease (IHD), are the most important cause of death and disability in the majority of low- and lower-middle-income countries (LLMICs). In these countries, IHD mortality rates are significantly greater in individuals of a low socioeconomic status (SES). Main text Three important focus areas for decreasing IHD mortality among those of low SES in LLMICs are (1) acute coronary care; (2) cardiac rehabilitation and secondary prevention; and (3) primary prevention. Greater mortality in low SES patients with acute coronary syndrome is due to lack of awareness of symptoms in patients and primary care physicians, delay in reaching healthcare facilities, non-availability of thrombolysis and coronary revascularization, and the non-affordability of expensive medicines (statins, dual anti-platelets, renin-angiotensin system blockers). Facilities for rapid diagnosis and accessible and affordable long-term care at secondary and tertiary care hospitals for IHD care are needed. A strong focus on the social determinants of health (low education, poverty, working and living conditions), greater healthcare financing, and efficient primary care is required. The quality of primary prevention needs to be improved with initiatives to eliminate tobacco and trans-fats and to reduce the consumption of alcohol, refined carbohydrates, and salt along with the promotion of healthy foods and physical activity. Efficient primary care with a focus on management of blood pressure, lipids and diabetes is needed. Task sharing with community health workers, electronic decision support systems, and use of fixed-dose combinations of blood pressure-lowering drugs and statins can substantially reduce risk factors and potentially lead to large reductions in IHD. Finally, training of physicians, nurses, and health workers in IHD prevention should be strengthened. Conclusion The management and prevention of IHD in individuals with a low SES in LLMICs are poor. Greater availability, ...
    Keywords Ischemic heart disease ; Cardiovascular diseases ; Risk factors ; Acute coronary syndrome ; Secondary prevention ; Primary prevention ; Medicine ; R
    Subject code 360 ; 610
    Language English
    Publishing date 2019-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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