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  1. Article: Potential Uses of

    Subramanian, Murukesan / Selvaraj, Kishore Kumar / Jagannathan, Raghunathan / Rajendran, Swaminathan / Rajendran, Deepika / Madapusi, Balaji Thodur

    Journal of pharmacy & bioallied sciences

    2023  Volume 15, Issue Suppl 1, Page(s) S40–S45

    Abstract: Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned ... ...

    Abstract Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned areas of orthodontics.
    Language English
    Publishing date 2023-07-05
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.jpbs_74_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparative Evaluation of Gingival Depigmentation by Scalpel, Electrosurgery, and Laser: A 14 Months' Follow-up Study.

    Jagannathan, Raghunathan / Rajendran, Swaminathan / Balaji, Thodur Madapusi / Varadarajan, Saranya / Sridhar, Lakshmi Priya

    The journal of contemporary dental practice

    2020  Volume 21, Issue 10, Page(s) 1159–1164

    Abstract: Aim and objective: The aim of the study was to compare three different techniques using scalpel, electrosurgery, and laser for gingival depigmentation in terms of pain, discomfort, duration of procedure, wound healing, and repigmentation.: Materials ... ...

    Abstract Aim and objective: The aim of the study was to compare three different techniques using scalpel, electrosurgery, and laser for gingival depigmentation in terms of pain, discomfort, duration of procedure, wound healing, and repigmentation.
    Materials and methods: Thirty patients in the age range of 24-38 years were briefed about the surgical procedure and an informed consent was obtained and they were randomly allocated into three groups of 10 individuals (5 males and 5 females) each: those undergoing depigmentation with scalpel (group I), electrosurgery (group II), and diode lasers (Biolase) (group III). Individuals of all three groups were asked to describe the level of pain and discomfort by using the visual analog scale (VAS) 2 hours, 24 hours, and 1 week postoperatively. Further, the groups were compared based on duration of procedure, wound healing, and repigmentation at the end of 14 months.
    Results: All the groups showed a decrease in the pain levels, which was statistically highly significant 1 week postoperatively when compared 24 hours postoperatively. There was a statistically significant difference in the pain levels between the scalpel, electrosurgery, and lasers groups after 24 hours (
    Conclusion: The rising concern for esthetic demand of an individual requires the removal of hyperpigmented gingival areas to create a confident and pleasing smile, which could be easily attained by using laser.
    Clinical significance: Laser is an effective and fast tool that causes less pain, discomfort, faster healing, and delayed repigmentation compared with scalpel or electrosurgery for gingival depigmentation.
    MeSH term(s) Adult ; Electrosurgery ; Esthetics, Dental ; Female ; Follow-Up Studies ; Gingiva ; Humans ; Laser Therapy ; Male ; Young Adult
    Language English
    Publishing date 2020-10-01
    Publishing country India
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1526-3711
    ISSN (online) 1526-3711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Thermoreversible

    Rajendran, Swaminathan / Kumar, K Sathesh / Ramesh, S / Rao, Suresh Ranga

    International journal of pharmaceutical investigation

    2017  Volume 7, Issue 2, Page(s) 101–106

    Abstract: Objective: The aim of this : Subjects and methods: Preformulation studies (Fourier transform infrared and differential scanning calorimetry) to assess the interaction between SMV and MC and PM were performed before gel formulation. Keeping the ... ...

    Abstract Objective: The aim of this
    Subjects and methods: Preformulation studies (Fourier transform infrared and differential scanning calorimetry) to assess the interaction between SMV and MC and PM were performed before gel formulation. Keeping the concentration of SMV at 2.2%, the concentration of PM and MC was altered to formulate
    Results: The preformulation studies showed that there is no interaction between the polymer and drug based on the rheological studies of different formulation, the formulation. F8 gels at 37°C and attains a viscosity of 4150 cps.
    Conclusions: PM 25% and MC 5% formed an ideal thermosensitive injectable gel at 37°C for subgingival delivery of SMV and also show controlled drug release for the period of 10 days
    Language English
    Publishing date 2017-04-08
    Publishing country India
    Document type Journal Article
    ISSN 2230-973X
    ISSN 2230-973X
    DOI 10.4103/jphi.JPHI_26_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Linking periodontitis and adverse pregnancy outcomes through CD14+ CD16+ monocytes.

    Jagannathan, Raghunathan / Balaji, Thodur Madapusi / Varadarajan, Saranya / Bhuvaneswari, B / Venkatakrishnan, C J / Lakshmi Priya, S / Rajendran, Swaminathan / Sayed, Mohammed E / Mugri, Maryam H / Patil, Shankargouda

    Medical hypotheses

    2021  Volume 153, Page(s) 110637

    Abstract: One of the prevalent medical issues that deserve global attention is adverse pregnancy outcomes and preterm low birth weight deliveries which have a significant impact on neonatal health. Periodontitis has been implicated as a significant risk factor for ...

    Abstract One of the prevalent medical issues that deserve global attention is adverse pregnancy outcomes and preterm low birth weight deliveries which have a significant impact on neonatal health. Periodontitis has been implicated as a significant risk factor for adverse effects in pregnancy. Elevated levels of periodontal pathogenic bacteria and proinflammatory cytokines which are pathognomonic features of periodontitis are believed to cause placental infection and premature rupture of the amniotic membrane consequently leading to preterm delivery. The role of CD14+CD16+ monocytes as a causal link between periodontitis and adverse pregnancy outcomes has not been researched so far, although an elevation of these cells has been independently demonstrated in both conditions. With the available background information, this hypothesis attempts to derive a mechanistic link between periodontitis and adverse pregnancy outcomes through the participation of CD14+CD16+ monocytes.
    MeSH term(s) Female ; Humans ; Infant, Newborn ; Monocytes ; Periodontitis ; Placenta ; Pregnancy ; Pregnancy Outcome ; Premature Birth
    Language English
    Publishing date 2021-06-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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