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Article ; Online: High-throughput virtual screening and molecular dynamics simulation reveals NPC170742 a novel chalconoid compound as a potential inhibitor of D-glycero-D-manno-heptose-1,7-bisphosphate 7-phosphatase in

Rajendran, Vijayakumar / Ponnuraj, Karthe

Journal of biomolecular structure & dynamics

2023 , Page(s) 1–11

Abstract: Helicobacter ... ...

Abstract	Helicobacter pylori
Language	English
Publishing date	2023-09-18
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2023.2259483
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Article ; Online: Isolation, identification of pathogenic Acanthamoeba from drinking and recreational water sources in Saudi Arabia

Rajendran Vijayakumar

Journal of Advanced Veterinary and Animal Research, Vol 5, Iss 4, Pp 439-

2018 Volume 444

Abstract: Objective: The present study was conducted to isolate and identify the Acanthamoeba species from various water sources such as drinking water, tap water, swimming pool, and other recreational water. Materials and methods: During the study period, 57 ... ...

Abstract	Objective: The present study was conducted to isolate and identify the Acanthamoeba species from various water sources such as drinking water, tap water, swimming pool, and other recreational water. Materials and methods: During the study period, 57 water samples were collected from various sources such as tap water, drinking water, swimming pool, and recreational water. All samples were processed and cultured on non-nutrient agar medium (NNA) with Escherichia coli overlay for the isolation of Acanthamoeba species. Organism identified based on the microscopic morphology of cyst and trophozoites forms. The pathogenicity of Acanthamoeba was analyzed by thermotolerance and osmotolerance assays. Results: Acanthamoeba were detected in 10 out of 57 (17.5%) examined water samples. The high percentage of positivity was observed in bore well water stored in tanks (37.5%) and in recreational water samples (26.7%). All processed drinking water samples were free from Acanthamoeba. Based on pathogenicity test assays, four (40%) were pathogenic and three (30%) were non-pathogenic. The observed frequency of Acanthamoeba spp. was compared with available literature worldwide. Conclusion: This study is the first report showing the distribution of Acanthamoeba in various water sources in the central region of Saudi Arabia and confirms that the high percentage presence of pathogenic strains in recreational water could threat contact lens wearers. Further research works are required to identify the prevalence of pathogenic Acanthamoeba from various water sources in Saudi Arabia. [J Adv Vet Anim Res 2018; 5(4.000): 439-444]
Keywords	Acanthamoeba ; cysts ; drinking water ; non-nutrient agar ; swimming pool ; trophozoites ; Veterinary medicine ; SF600-1100
Subject code	500
Language	English
Publishing date	2018-12-01T00:00:00Z
Publisher	Network for the Veterinarians of Bangladesh
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Environmental, economic, and performance assessment of solar air heater with inclined and winglet baffle

Rajendran, Vijayakumar / Singaraj, Karthik / Rajarathinam, Jayavenkatesh

Environ Sci Pollut Res. 2023 Feb., v. 30, no. 6 p.14337-14352

2023

Abstract: To investigate the solar air heater’s (SAH) effectiveness, experiments are conducted using flat plate and artificially roughened plate in terms of inclined and winglet baffles over the collector surface. This proposed system collector plate is made up of ...

Abstract	To investigate the solar air heater’s (SAH) effectiveness, experiments are conducted using flat plate and artificially roughened plate in terms of inclined and winglet baffles over the collector surface. This proposed system collector plate is made up of inclined and winglet ribs and serves as an artificial roughness generator. Air stream of 0.01, 0.02, and 0.03 kg/s are used in the experiment. To determine the improvement in the proposed work, these experimental results are compared with flat plate SAH. This proposed work offers a greater efficiency, useful energy gain, and lower top heat loss than a conventional SAH. At 0.03 kg/s system efficiency and useful energy gain reach their peak. Experimental day’s average efficiency of a SAH with inclined and winglet baffles is 30.8%, 52.7%, and 72.9%, respectively, for the examined cases, and it is 11%, 13.8%, and 22.2% more effective than a flat surface SAH. For the investigated air flow rates, the proposed system gains 36.2%, 24.2%, and 28.9% more energy than flat plate SAH. Substantial reductions in top losses of up to 8.48%, 7.28%, and 7.27% have been reported at the specified flow rates, respectively. Energy metrics and economic study performed show the payback time, production factor, life cycle conversion efficiency, and economic values of the proposed SAH are optimum.
Keywords	air flow ; energy ; heat ; roughness ; solar heaters
Language	English
Dates of publication	2023-02
Size	p. 14337-14352.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-23213-3
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Article ; Online: Effect of graphene nanopaint on performance of solar air heater attached with inclined and winglet baffles.

Dharmaraj, Santhosh Kumar / Ramasubbu, Harichandran / Rajendran, Vijayakumar / Ravichandran, Praveenkumar

Environmental science and pollution research international

2023 Volume 30, Issue 37, Page(s) 87330–87342

Abstract: Solar air heater is widely used for drying and industrial processing application. Different artificial roughened surfaces and coatings over the absorber plates are used to improve their performance of solar air heater by increasing absorption and heat ... ...

Abstract	Solar air heater is widely used for drying and industrial processing application. Different artificial roughened surfaces and coatings over the absorber plates are used to improve their performance of solar air heater by increasing absorption and heat transfer. In this proposed work, the graphene-based nanopaint is prepared by wet chemical and ball milling method and the prepared graphene nanopaint is characterized using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The prepared graphene-based nanopaint is coated on the absorber plate by conventional coating method. The thermal performance of the solar air heater coated with traditional black paint and graphene nanopaint is evaluated and compared. The day's maximum energy gain by the graphene-coated solar air heater is 972.84 W, whereas traditional black paint is only 808.02 W. The average energy gain of graphene nanopaint is 655.85 W, which is 12.9% higher than the traditional black paint. The maximum thermal efficiency for solar air heater coated with graphene nanopaint is 81%. Also the average thermal efficiency of graphene-coated solar air heater is 72.5%, which has a 13.24% higher average thermal efficiency when compared to conventional black paint-coated solar air heater. The average top heat loss for solar air heater coated with graphene nanopaint is 8.48% lower than solar air heater with traditional black paint.
MeSH term(s)	Graphite/chemistry ; Sunlight ; Hot Temperature ; Desiccation ; Paint
Chemical Substances	Graphite (7782-42-5)
Language	English
Publishing date	2023-07-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-28646-y
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Article ; Online: Environmental, economic, and performance assessment of solar air heater with inclined and winglet baffle.

Rajendran, Vijayakumar / Singaraj, Karthik / Rajarathinam, Jayavenkatesh

Environmental science and pollution research international

2022 Volume 30, Issue 6, Page(s) 14337–14352

Abstract: To investigate the solar air heater's (SAH) effectiveness, experiments are conducted using flat plate and artificially roughened plate in terms of inclined and winglet baffles over the collector surface. This proposed system collector plate is made up of ...

Abstract	To investigate the solar air heater's (SAH) effectiveness, experiments are conducted using flat plate and artificially roughened plate in terms of inclined and winglet baffles over the collector surface. This proposed system collector plate is made up of inclined and winglet ribs and serves as an artificial roughness generator. Air stream of 0.01, 0.02, and 0.03 kg/s are used in the experiment. To determine the improvement in the proposed work, these experimental results are compared with flat plate SAH. This proposed work offers a greater efficiency, useful energy gain, and lower top heat loss than a conventional SAH. At 0.03 kg/s system efficiency and useful energy gain reach their peak. Experimental day's average efficiency of a SAH with inclined and winglet baffles is 30.8%, 52.7%, and 72.9%, respectively, for the examined cases, and it is 11%, 13.8%, and 22.2% more effective than a flat surface SAH. For the investigated air flow rates, the proposed system gains 36.2%, 24.2%, and 28.9% more energy than flat plate SAH. Substantial reductions in top losses of up to 8.48%, 7.28%, and 7.27% have been reported at the specified flow rates, respectively. Energy metrics and economic study performed show the payback time, production factor, life cycle conversion efficiency, and economic values of the proposed SAH are optimum.
MeSH term(s)	Sunlight ; Solar Energy
Language	English
Publishing date	2022-09-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-23213-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Experimental study on the thermal performance of a solar air heater integrated with multi-geometry arrangements over the absorber plate.

Rajendran, Vijayakumar / Ramasubbu, Harichandran / Rajarathinam, Jaya Venkatesh / Pichandi, Ramanan

Environmental science and pollution research international

2022 Volume 29, Issue 25, Page(s) 38331–38345

Abstract: A solar air heater (SAH) is investigated experimentally by employing multi-geometry arrangements over the absorber plate. In the current work, the absorber plate is designed with rectangular ribs, slits, and cylinders. For the proposed system, this multi- ...

Abstract	A solar air heater (SAH) is investigated experimentally by employing multi-geometry arrangements over the absorber plate. In the current work, the absorber plate is designed with rectangular ribs, slits, and cylinders. For the proposed system, this multi-geometry arrangement serves as an artificial roughness (baffles). Different airflow rates of 0.01, 0.02, 0.03, and 0.04 kg/s are used in the experiment. The results of this experiment are compared to those of a conventional SAH to assess the improvement. Compared to a conventional SAH, the proposed system has higher thermal efficiency, energy gain, and minimal top loss. The highest thermal efficiency and energy gain are observed at a mass flow rate of 0.04 kg/s. Increasing the mass flow rate increases the system's performance. For the analyzed flow rates, the average thermal efficiency of a SAH with multi-geometry baffle is 40.8%, 58.2%, 68.2%, and 77.4%. For the same flow rates, it is 12.8%, 10.2%, 12.3%, and 13.5% higher than a conventional SAH. For the same examined air flow rates, the suggested air heater gains 31.9%, 21%, 19.2%, and 20.8% more energy than conventional SAH. Significant decreases in top losses are reported up to 8.1%, 7.3%, 7.2%, and 6.5%, respectively for the specified flow rates.
Language	English
Publishing date	2022-01-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-18830-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Experimental study on the thermal performance of a solar air heater integrated with multi-geometry arrangements over the absorber plate

Rajendran, Vijayakumar / Ramasubbu, Harichandran / Rajarathinam, Jaya Venkatesh / Pichandi, Ramanan

Environ Sci Pollut Res. 2022 May, v. 29, no. 25 p.38331-38345

2022

Abstract	A solar air heater (SAH) is investigated experimentally by employing multi-geometry arrangements over the absorber plate. In the current work, the absorber plate is designed with rectangular ribs, slits, and cylinders. For the proposed system, this multi-geometry arrangement serves as an artificial roughness (baffles). Different airflow rates of 0.01, 0.02, 0.03, and 0.04 kg/s are used in the experiment. The results of this experiment are compared to those of a conventional SAH to assess the improvement. Compared to a conventional SAH, the proposed system has higher thermal efficiency, energy gain, and minimal top loss. The highest thermal efficiency and energy gain are observed at a mass flow rate of 0.04 kg/s. Increasing the mass flow rate increases the system’s performance. For the analyzed flow rates, the average thermal efficiency of a SAH with multi-geometry baffle is 40.8%, 58.2%, 68.2%, and 77.4%. For the same flow rates, it is 12.8%, 10.2%, 12.3%, and 13.5% higher than a conventional SAH. For the same examined air flow rates, the suggested air heater gains 31.9%, 21%, 19.2%, and 20.8% more energy than conventional SAH. Significant decreases in top losses are reported up to 8.1%, 7.3%, 7.2%, and 6.5%, respectively for the specified flow rates.
Keywords	air ; air flow ; energy ; mass flow ; roughness ; solar heaters
Language	English
Dates of publication	2022-05
Size	p. 38331-38345.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-18830-x
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Article ; Online: Assessment of airborne endotoxin in sandstorm dust and indoor environments using a novel passive sampling device in Al Zulfi city, Saudi Arabia – Establishing threshold exposure levels

Rajendran Vijayakumar / Faiz Abdulaziz Alfaiz / Esam S. Al-Malki / Tim Sandle

Saudi Journal of Biological Sciences, Vol 28, Iss 2, Pp 1257-

2021 Volume 1266

Abstract: The impact of sandstorm dust events affects local air quality and public health. These issues are becoming of greater concern in Saudi Arabia. There is a significant lack of research on airborne endotoxin exposure and analysis in the Middle East ... ...

Abstract	The impact of sandstorm dust events affects local air quality and public health. These issues are becoming of greater concern in Saudi Arabia. There is a significant lack of research on airborne endotoxin exposure and analysis in the Middle East countries and no coherent body of research exists focusing on sandstorm dust in worldwide. In this study, we used a novel design of an aluminum foil plate (AFP) electrostatic dust cloth (EDC) for the passive air sampling of sandstorm dust. A total of 38 sandstorm dust samples were collected during sandstorm episodes occurring between January and April 2020 in both indoor (7 days, n = 20) and outdoor environments (24 h, n = 18). After exposure, and following an extraction procedure, bacterial endotoxin levels were measured using the Limulus Amoebocyte Lysate (LAL) gel clot method. The study highlights that the airborne endotoxin level observed was between 10 and 200 EU/m2 in both indoor and outdoor environments, during a sandstorm event. Agricultural activities and farmhouses observed higher airborne endotoxin levels. In general, increased endotoxin levels were related to the severity of the sandstorms. Given that the observed values were high as per existing guidelines for respiratory health, we recommend the setting an occupational airborne exposure limit for bacterial endotoxin. This is the first report and further studies across various sandstorm-hit regions will need to be undertaken, together with various sampling methods, in order to assess for seasonal and geographic trends.
Keywords	Airborne endotoxin ; Bacterial endotoxin ; Dust storms ; Electrostatic dust cloth ; Indoor ; LAL test ; Biology (General) ; QH301-705.5
Subject code	333
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Enhancing the performance of a solar air heater by employing the broken V-shaped ribs.

Rajendran, Vijayakumar / Vikram, Muthuraman Ponrajan / Kim, Sung Chul / Gullo, Paride / Alodhayb, Abdullah / Pandiaraj, Saravanan / Prabakaran, Rajendran

Environmental science and pollution research international

2023 Volume 30, Issue 31, Page(s) 77807–77818

Abstract: This work aims to enhance the performance of a solar air heater (SAH) by introducing broken V-ribs as roughness elements on the absorber plate. The unit with a conventional flat absorber plate is referred to as the "FSAH," while the unit with a broken V- ... ...

Abstract	This work aims to enhance the performance of a solar air heater (SAH) by introducing broken V-ribs as roughness elements on the absorber plate. The unit with a conventional flat absorber plate is referred to as the "FSAH," while the unit with a broken V-rib-shaped absorber plate is called the "VSAH." The experiment was performed for three air velocities: 25 m/s, 20 m/s, and 15 m/s and the corresponding air flow rates were 0.037 kg/s, 0.031 kg/s, and 0.023 kg/s, respectively. The results showed that the maximum temperature was experienced on the absorber plate, followed by the glass plate for both SAHs. Overall, the average absorber and glass plate temperatures of the VSAH were 0.6-1.4 °C and 0.4-1.9 °C lower than those of the FSAH. Compared to the FSAH, the experimental results showed that the VSAH experienced useful power and thermal efficiency that were 16.6-19.8% and 15.7-20.4% higher, respectively, while the top surface heat losses were found to decrease by 2.1-8.1%. Due to the disrupted air paths in the VSAH, the observed pressure drop was 113.3-133.3% higher than that of the FSAH. More impotently, the thermo-hydraulic performance factor was always higher 1 and the observed values were 1.48, 1.39, and 1.24 at the v
MeSH term(s)	Sunlight ; Temperature ; Ribs ; Solar Energy
Language	English
Publishing date	2023-06-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-27814-4
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Article ; Online: Mutational signatures on ischemic stroke-associated genes in Saudi human genome

Rajendran Vijayakumar / Palanisamy Manikandan / Faiz Alfaiz / Mohammad Saleh Al Aboodi / Moorthy Kannaiyan / Suresh Mickymaray / Balaji Banoth / Alaguraj Veluchamy

Journal of King Saud University: Science, Vol 34, Iss 6, Pp 102151- (2022)

2022

Abstract: Stroke is a neurological syndrome, and it leads to 5.8 million mortalities worldwide annually. In the Kingdom of Saudi Arabia (KSA), stroke was predicted to have 57%-67% incidence rate against a population growth rate of 12.8%. Current state of the art ... ...

Abstract	Stroke is a neurological syndrome, and it leads to 5.8 million mortalities worldwide annually. In the Kingdom of Saudi Arabia (KSA), stroke was predicted to have 57%-67% incidence rate against a population growth rate of 12.8%. Current state of the art in stroke research in KSA is limited to epidemiological, prevalence data and there is a lack of genetic basis of stroke among Saudi individuals and their risk for disease traits. Despite the better health care services in KSA, a genetic approach is needed for stroke, as it is a manifestation of both monogenic Mendelian and polygenic disorder. Here, we propose to analyze and annotate Saudi specific genome variations associated with stroke. In this study, we explored the non-coding and genic regions using 28 whole genomes of individuals from Saudi population. We explored stroke susceptible genes for additional variation. Analysis of 49 genes which are stroke-associated for single nucleotide polymorphism (SNPs), obtained from whole genomes, reveals variations in atleast 13 candidate genes. In conclusion, whole genome sequencing and annotation of SNPs in the population of Saudi Arabia provide an insight into genetics of stroke. This analysis furnish a list of probable novel Saudi specific mutations that could be associated with stroke, once a cohort of disease data can beobtained. In addition, we conjecture that, by identifying these mutational signatures, stroke subtype and susceptibility to stroke can be uncovered in the future.
Keywords	Functional annotation ; Gene ontology ; Genome variation ; Ischemic stroke ; Single nucleotide polymorphism ; Science (General) ; Q1-390
Subject code	590
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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