LIVIVO - Search results -

Search results

Result 1 - 10 of total 15

Search options

Article ; Online: Protective role of N-acetylcysteine and Sulodexide on endothelial cells exposed on patients' serum after SARS-CoV-2 infection.

Rajewska-Tabor, Justyna / Sosińska-Zawierucha, Patrycja / Pyda, Malgorzata / Lesiak, Maciej / Bręborowicz, Andrzej

Frontiers in cellular and infection microbiology

2023 Volume 13, Page(s) 1268016

Abstract: Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage. The ... ...

Abstract	Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage. The influence on coronary artery endothelial cells of serum collected after 4 ± 1 months from coronavirus infection was studied. The concentrations of serum samples of interleukin 6, von Willebrand Factor, tissue Plasminogen Activator, and Plasminogen Activator Inhibitor-1 were studied. The cultures with serum of patients after coronavirus infection were incubated with N-acetylcysteine and Sulodexide to estimate their potential protective role. The blood inflammatory parameters were increased in the group of cultures incubated with serum from patients after coronavirus infection. Supplementation of the serum from patients after coronavirus infection with N-acetylcysteine or Sulodexide reduced the synthesis of interleukin 6 and von Willebrand Factor. No changes in the synthesis of tissue Plasminogen Activator were observed. N-acetylcysteine reduced the synthesis of Plasminogen Activator Inhibitor-1. N-acetylcysteine and Sulodexide increased the tPA/PAI-1 ratio. N-acetylcysteine may have a role in reducing the myocardial injury occurring in the post-COVID-19 syndrome. Sulodexide can also play a protective role in post-COVID-19 patients.
MeSH term(s)	Humans ; COVID-19 ; Endothelial Cells ; Tissue Plasminogen Activator ; Acetylcysteine/pharmacology ; Interleukin-6 ; Post-Acute COVID-19 Syndrome ; von Willebrand Factor ; SARS-CoV-2
Chemical Substances	Tissue Plasminogen Activator (EC 3.4.21.68) ; glucuronyl glucosamine glycan sulfate (75HGV0062C) ; Acetylcysteine (WYQ7N0BPYC) ; Interleukin-6 ; von Willebrand Factor
Language	English
Publishing date	2023-12-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2023.1268016
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Protective role of N-acetylcysteine and Sulodexide on endothelial cells after SARS-CoV-2 infection

Rajewska-Tabor, Justyna / Sosinska, Patrycja / Pyda, Malgorzata / Breborowicz, Andrzej

bioRxiv

Abstract: Objective: Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and in the result aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial ... ...

Abstract	Objective: Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and in the result aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage. Approach and Results: The influence on coronary artery endothelial cells of serum collected after 4+/-1 months from coronavirus infection was studied. The concentrations of serum samples of interleukin 6, von Willebrand Factor, tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 were studied. The cultures with serum of patients after coronavirus infection were incubated with N-acetylocysteine and Sulodexide to estimate their potential protective role. The blood inflammato-ry parameters were increased in the group of cultures incubated with serum from patients after coronavirus infection. Supplementation of the serum from patients after coronavirus infection with N-acetylcysteine or Sulodexide reduced the synthesis of interleukin 6, von Willebrand Fac-tor. No changes in the synthesis of tissue Plasminogen Activator were observed. N-acetylcysteine reduced the synthesis of Plasminogen Activator Inhibitor-1. N-acetylcysteine and Sulodexide increased the tPA/PAI-1 ratio. Conclusion: N-acetylcysteine may have a role in reducing the myocardial injury occurring in the post-COVID-19 syndrome. Sulodexide can also play a protective role in post-COVID-19 patients.
Keywords	covid19
Language	English
Publishing date	2023-07-24
Publisher	Cold Spring Harbor Laboratory
Document type	Article ; Online
DOI	10.1101/2023.07.19.549800
Database	COVID19

Full text online

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Massive atrial thrombus in sinus rhythm cardiac amyloidosis is not a wild goose chase?

Gościniak, Piotr / Baumert, Bartłomiej / Rajewska-Tabor, Justyna / Jędrzychowska-Baraniak, Joanna / Pyda, Małgorzata / Machaliński, Bogusław

Kardiologia polska

2022 Volume 80, Issue 4, Page(s) 507–508

MeSH term(s)	Amyloidosis/complications ; Arrhythmias, Cardiac ; Atrial Fibrillation ; Heart Diseases/diagnostic imaging ; Heart Diseases/etiology ; Heart Diseases/surgery ; Humans ; Thrombosis/diagnostic imaging ; Thrombosis/etiology ; Thrombosis/surgery
Language	English
Publishing date	2022-05-10
Publishing country	Poland
Document type	Journal Article
ZDB-ID	411492-9
ISSN	1897-4279 ; 0022-9032
ISSN (online)	1897-4279
ISSN	0022-9032
DOI	10.33963/KP.a2022.0073
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 598: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 474: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Left, but not right, ventricular status determines heart failure in adults with Ebstein anomaly - A case-control study based on magnetic resonance.

Ciepłucha, Aleksandra / Trojnarska, Olga / Rajewska-Tabor, Justyna / Bartczak-Rutkowska, Agnieszka / Kramer, Lucyna / Pyda, Malgorzata

International journal of cardiology

2022 Volume 358, Page(s) 39–44

Abstract: Background: Ebstein anomaly (EA) is a congenital heart defect affecting the right heart. Heart failure (HF) is a significant complication in adults with EA. It may result not only from the right ventricle (RV), but also from the left ventricle (LV) ... ...

Abstract	Background: Ebstein anomaly (EA) is a congenital heart defect affecting the right heart. Heart failure (HF) is a significant complication in adults with EA. It may result not only from the right ventricle (RV), but also from the left ventricle (LV) abnormalities. We evaluate the size and function of both ventricles in patients with EA in cardiac magnetic resonance (CMR); to assess their association with the clinical markers of HF. Methods: Study group: 37 unoperated adults with EA (mean age 43.0 ± 14.4y, 21[56.8%] males). Controls: 25 volunteers (mean age 39.9 ± 10.9y, 15[60%] males). Study protocol included: CMR [ejection fraction (EF), end-diastolic (EDVind) and stroke volumes (SVind) indexed by body surface area]; cardiopulmonary test (peak VO2, %peak VO2, VE/VCO2 slope). Results: Size and systolic function of LV were reduced comparing to the controls [LVEDVind (ml/m2): 63.7(range 38.7-94.2) vs. 79.3(48.7-105.1), p < 0.001; LV SVind (ml/m2): 35.8(22.9-55.1) vs. 49.2(37.8-71.7), p < 0.0001; LVEF(%): 58.3(34-70.5) vs. 62.0(52.0-77.0), p = 0.009]. RV was enlarged comparing to the controls [RVEDVind (ml/m2): 124.3(52.8-378.9) vs. 83.0(64.0-102.0), p < 0.0001) with impaired systolic function (RV SVind (ml/m2): 22.7(11.1-74.1) vs. 48.0(37.8-71.7), p < 0.0001; RVEF(%): 38.0(21.0-66.1) vs. 59.0(49.0-69.0), p < 0.0001). A significant correlation was found between LVEDVind vs. peakVO2 (r = 0.52, p = 0.001); LV SVind vs. peakVO2 (r = 0.47,p = 0.005). There was no correlation between the right ventricular status and exercise capacity. Conclusions: In adults with Ebstein anomaly the size of left ventricle is reduced, right ventricle is enlarged; the function of both is impaired. Abnormal exercise capacity is associated with left ventricular status. Ventricular interdependence probably plays a role in heart failure pathomechanism.
MeSH term(s)	Adult ; Case-Control Studies ; Ebstein Anomaly/diagnostic imaging ; Female ; Heart Failure/complications ; Heart Failure/diagnostic imaging ; Heart Ventricles/diagnostic imaging ; Humans ; Magnetic Resonance Spectroscopy ; Male ; Middle Aged ; Stroke Volume ; Ventricular Function, Right
Language	English
Publishing date	2022-04-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2022.04.066
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1673: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: A Twenty-Year Follow-Up of Adults with Ebstein Anomaly with Special Focus on Supraventricular Arrhythmias, Supraventricular Arrhythmias and Effectiveness of Catheter Ablation in 20-Year Follow-Up of Adults with Ebstein Anomaly.

Nartowicz, Sonia Alicja / Ciepłucha, Aleksandra / Waśniewski, Michał / Miechowicz, Izabela / Rajewska-Tabor, Justyna / Bartczak-Rutkowska, Agnieszka / Lesiak, Maciej / Pyda, Małgorzata / Trojnarska, Olga

Journal of clinical medicine

2024 Volume 13, Issue 7

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2024-04-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13072039
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Changing appearance of lipomatous hypertrophy of the interatrial septum on positron emission tomography scan.

Siminiak, Natalia / Rajewska-Tabor, Justyna / Pyda, Małgorzata / Czepczyński, Rafał / Ruchała, Marek

Kardiologia polska

2021 Volume 79, Issue 9, Page(s) 1032–1033

MeSH term(s)	Atrial Septum/diagnostic imaging ; Heart Neoplasms/diagnostic imaging ; Humans ; Hypertrophy/diagnostic imaging ; Lipomatosis/diagnostic imaging ; Positron-Emission Tomography
Language	English
Publishing date	2021-06-24
Publishing country	Poland
Document type	Journal Article
ZDB-ID	411492-9
ISSN	1897-4279 ; 0022-9032
ISSN (online)	1897-4279
ISSN	0022-9032
DOI	10.33963/KP.a2021.0046
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 598: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 474: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Myocarditis associated with COVID‑19 vaccination in three male teenagers.

Łaźniak-Pfajfer, Agata / Surmacz, Rafał / Rajewska-Tabor, Justyna / Pyda, Małgorzata / Lesiak, Maciej / Bobkowski, Waldemar

Polish archives of internal medicine

2021 Volume 132, Issue 2

MeSH term(s)	Adolescent ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Male ; Myocarditis/chemically induced ; SARS-CoV-2 ; Vaccination
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2021-12-01
Publishing country	Poland
Document type	Journal Article ; Comment
ZDB-ID	123500-x
ISSN	1897-9483 ; 0032-3772
ISSN (online)	1897-9483
ISSN	0032-3772
DOI	10.20452/pamw.16160
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A distinct septal pattern of late gadolinium enhancement specific for COVID-induced myocarditis: A multicenter cardiovascular magnetic resonance study.

Haberka, Maciej / Rajewska-Tabor, Justyna / Wojtowicz, Dagmara / Jankowska, Anna / Miszalski-Jamka, Karol / Janus, Magdalena / Dorniak, Karolina / Kulawiak-Gałąska, Dorota / Stasiow, Bartłomiej / Rozmiarek, Szymon / Fijałkowska, Jadwiga / Elikowski, Waldemar / Ławrynowicz, Marzena / Śpiewak, Mateusz / Koziński, Marek / Pyda, Małgorzata

Kardiologia polska

2023 Volume 81, Issue 5, Page(s) 463–471

Abstract: Background: COVID-19 is a great medical challenge as it provokes acute respiratory distress and has pulmonary manifestations and cardiovascular (CV) consequences.: Aims: This study compared cardiac injury in COVID-19 myocarditis patients with non- ... ...

Abstract	Background: COVID-19 is a great medical challenge as it provokes acute respiratory distress and has pulmonary manifestations and cardiovascular (CV) consequences. Aims: This study compared cardiac injury in COVID-19 myocarditis patients with non-COVID-19 myocarditis patients. Methods: Patients who recovered from COVID-19 were scheduled for cardiovascular magnetic resonance (CMR) owing to clinical myocarditis suspicion. The retrospective non-COVID-19 myocarditis (2018-2019) group was enrolled (n = 221 patients). All patients underwent contrast-enhanced CMR, the conventional myocarditis protocol, and late gadolinium enhancement (LGE). The COVID study group included 552 patients at a mean (standard deviation [SD]) age of 45.9 (12.6) years. Results: CMR assessment confirmed myocarditis-like LGE in 46% of the cases (68.5% of the segments with LGE <25% transmural extent), left ventricular (LV) dilatation in 10%, and systolic dysfunction in 16% of cases. The COVID-19 myocarditis group showed a smaller median (interquartile range [IQR]) LV LGE (4.4% [2.9%-8.1%] vs. 5.9% [4.4%-11.8%]; P <0.001), lower LV end-diastolic volume (144.6 [125.5-178] ml vs. 162.8 [136.6-194] ml; P <0.001), limited functional consequence (left ventricular ejection fraction, 59% [54.1%-65%] vs. 58% [52%-63%]; P = 0.01), and a higher rate of pericarditis (13.6% vs. 6%; P = 0.03) compared to non-COVID-19 myocarditis. The COVID-19-induced injury was more frequent in septal segments (2, 3, 14), and non-COVID-19 myocarditis showed higher affinity to lateral wall segments (P <0.01). Neither obesity nor age was associated with LV injury or remodeling in subjects with COVID-19 myocarditis. Conclusions: COVID-19-induced myocarditis is associated with minor LV injury with a significantly more frequent septal pattern and a higher pericarditis rate than non-COVID-19 myocarditis.
MeSH term(s)	Humans ; Middle Aged ; Myocarditis/etiology ; Myocarditis/complications ; Contrast Media ; Stroke Volume ; Gadolinium ; Ventricular Function, Left ; Retrospective Studies ; Magnetic Resonance Imaging, Cine/methods ; COVID-19/complications ; Myocardium/pathology ; Magnetic Resonance Spectroscopy ; Pericarditis ; Predictive Value of Tests
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2023-03-05
Publishing country	Poland
Document type	Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	411492-9
ISSN	1897-4279 ; 0022-9032
ISSN (online)	1897-4279
ISSN	0022-9032
DOI	10.33963/KP.a2023.0054
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 598: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 474: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Concomitance of COVID-19 and legionnaires' disease - a case series.

Elikowski, Waldemar / Fertała, Natalia / Zawodna-Marszałek, Magdalena / Chwiałkowska, Małgorzata / Połeć, Jakub / Lisiecka, Monika / Skrzywanek, Paweł / Rajewska-Tabor, Justyna / Zwoliński, Paweł / Drużdż, Artur / Pyda, Małgorzata / Żytkiewicz, Marcin

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

2022 Volume 50, Issue 295, Page(s) 30–36

Abstract: Coronavirus disease-2019 (COVID-19) and legionnaires disease (LD) caused by Gram-negative water-born bacteria Legionella pneumophila show certain similarities, including a predisposition to pulmonary involvement and extrapulmonary manifestations in some ... ...

Abstract	Coronavirus disease-2019 (COVID-19) and legionnaires disease (LD) caused by Gram-negative water-born bacteria Legionella pneumophila show certain similarities, including a predisposition to pulmonary involvement and extrapulmonary manifestations in some of the patients infected. One disease can mimic the other, both can rarely coexist. Case series report: The authors describe 7 such cases (5 females), aged 51-90 years (mean 69.7 years) detected while screening 133 subjects with moderate to severe pneumonia and confirmed COVID- 19, which constituted 5.3% of the patients in whom urinary antigen test (UAT) for L. pneumophila was performed. The patients had multiple concomitant disorders: hypertension (6), heart failure (4), diabetes (4), obesity (4), coronary heart disease (3), chronic kidney disease (3), chronic obstructive pulmonary disease (3), anemia (3). Positive UAT was obtained at admission in 4 patients, and on 3rd, 11th and 14th days of hospitalization in the remaining 3 patients. One patient also had positive UAT for Streptococcus pneumoniae. We analyzed: radiological imaging, laboratory data (CRP, interleukin-6, procalcitonin, troponin I, BNP), ECG, echocardiography, treatment and outcome. Three patients required a modification of initial antibiotic therapy, two developed Clostridioides difficile infection. The duration of hospitalization ranged from 13 to 59 days (mean 24.3 days); two patients died. Conclusions: The authors suggest that the coexistence of COVID- 19 and LD may result in prolonged hospitalization, in increased mortality risk and in subsequent cardiovascular complications, including takotsubo syndrome (TTS) which was found in 2 cases, both presented as focal TTS (fTTS).
MeSH term(s)	Aged ; Aged, 80 and over ; COVID-19/complications ; Female ; Humans ; Legionella pneumophila ; Legionnaires' Disease/complications ; Legionnaires' Disease/diagnosis ; Middle Aged ; Pneumonia/complications ; SARS-CoV-2
Language	English
Publishing date	2022-03-12
Publishing country	Poland
Document type	Journal Article
ZDB-ID	1388406-2
ISSN	1426-9686
ISSN	1426-9686
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4780: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Persistent ductus arteriosus in old patient with atrial fibrillation.

Rajewska-Tabor, Justyna / Zabicki, Bartosz / Hrycow, Michal / Rozmiarek, Szymon / Pyda, Malgorzata

Journal of geriatric cardiology : JGC

2018 Volume 15, Issue 5, Page(s) 372–375

Language	English
Publishing date	2018-07-25
Publishing country	China
Document type	Journal Article
ZDB-ID	2421391-3
ISSN	1671-5411
ISSN	1671-5411
DOI	10.11909/j.issn.1671-5411.2018.05.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Full text online

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito