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  1. Article ; Online: Application of telemedicine in infectious diseases.

    Monfort-Vinuesa, Carlos / Gil-López, Pedro / Ramírez-Olivencia, Germán / Chivato-Pérez, Tomás / Coca-Benito, David / Mata-Forte, Tatiana

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2022  Volume 41, Issue 1, Page(s) 36–39

    Abstract: Introduction: Infectious pathologies can benefit from the application of Telemedicine (TM). This study provides a description of the infectious pathology treated by the Telemedicine Service of the Hospital Central de la Defensa Gómez Ulla (STM-HCDGU).!## ...

    Abstract Introduction: Infectious pathologies can benefit from the application of Telemedicine (TM). This study provides a description of the infectious pathology treated by the Telemedicine Service of the Hospital Central de la Defensa Gómez Ulla (STM-HCDGU).
    Methods: Analysis of the e-consultations made by members of the Armed Forces (FA) of Spain displaced to the area of ​​operations (ZO) in the period between 01/1/2015 and 31/12/2018 who developed infectious symptoms.
    Results: 127 infectious diseases were diagnosed, the most frequent being those of respiratory etiology and later malaria. Geographically Africa and embarked contingents were the most significant. It was necessary to evacuate 18 patients to the HCDGU, being the diagnosis of malaria the most frequent reason for evacuation, cause of the only fatal case.
    Conclusions: infectious diseases benefit from the application of TM, being an important tool for the diagnosis and treatment of these, constituting an opportunity to expand to other displaced or remote populations.
    MeSH term(s) Humans ; Communicable Diseases/diagnosis ; Communicable Diseases/therapy ; Telemedicine ; Malaria ; Hospitals ; Military Personnel
    Language English
    Publishing date 2022-07-07
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2022.06.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The Impact of Antibiotic Prophylaxis on a Retrospective Cohort of Hospitalized Patients with COVID-19 Treated with a Combination of Steroids and Tocilizumab.

    Membrillo de Novales, Francisco Javier / Ramírez-Olivencia, Germán / Mata Forte, Maj Tatiana / Zamora Cintas, María Isabel / Simón Sacristán, Maj María / Sánchez de Castro, María / Estébanez Muñoz, Miriam

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 10

    Abstract: Objectives: In the context of COVID-19, patients with a severe or critical illness may be more susceptible to developing secondary bacterial infections. This study aims to investigate the relationship between the use of prophylactic antibiotic therapy ... ...

    Abstract Objectives: In the context of COVID-19, patients with a severe or critical illness may be more susceptible to developing secondary bacterial infections. This study aims to investigate the relationship between the use of prophylactic antibiotic therapy and the occurrence of bacterial or fungal isolates following the administration of tocilizumab in hospitalized COVID-19 patients who had previously received steroids during the first and second waves of the pandemic in Spain.
    Methods: This retrospective observational study included 70 patients hospitalized with COVID-19 who received tocilizumab and steroids between January and December 2020. Data on demographics, comorbidities, laboratory tests, microbiologic results, treatment, and outcomes were collected from electronic health records. The patients were divided into two groups based on the use of antibiotic prophylaxis, and the incidence of bacterial and fungal colonizations/infections was analyzed.
    Results: Among the included patients, 45 patients received antibiotic prophylaxis. No significant clinical differences were observed between the patients based on prophylaxis use regarding the number of clinically diagnosed infections, ICU admissions, or mortality rates. However, the patients who received antibiotic prophylaxis showed a higher incidence of colonization by multidrug-resistant bacteria compared to that of the subgroup that did not receive prophylaxis. The most commonly isolated microorganisms were
    Language English
    Publishing date 2023-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12101515
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Application of telemedicine in infectious diseases.

    Monfort-Vinuesa, Carlos / Gil-López, Pedro / Ramírez-Olivencia, Germán / Chivato-Pérez, Tomás / Coca-Benito, David / Mata-Forte, Tatiana

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2021  

    Abstract: Introduction: Infectious pathologies can benefit from the application of Telemedicine (TM). This study provides a description of the infectious pathology treated by the Telemedicine Service of the Hospital Central de la Defensa Gómez Ulla (STM-HCDGU).!## ...

    Title translation Aplicación de la telemedicina en enfermedades infecciosas.
    Abstract Introduction: Infectious pathologies can benefit from the application of Telemedicine (TM). This study provides a description of the infectious pathology treated by the Telemedicine Service of the Hospital Central de la Defensa Gómez Ulla (STM-HCDGU).
    Methods: Analysis of the e-consultations made by members of the Armed Forces of Spain displaced to the area of operations in the period between 01/1/2015 and 31/12/2018 who developed symptoms of infectious diseases.
    Results: 127 infectious diseases were diagnosed, the most frequent being those of respiratory etiology and later malaria. Geographically Africa and embarked contingents were the most significant. It was necessary to evacuate 18 patients to the HCDGU, being the diagnosis of malaria the most frequent reason for evacuation, cause of the only fatal case.
    Conclusions: infectious diseases benefit from the application of TM, being an important tool for the diagnosis and treatment of these, constituting an opportunity to expand to other displaced or remote populations.
    Language Spanish
    Publishing date 2021-04-12
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2021.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incidence, Characteristics, Laboratory Findings and Outcomes in Acro-Ischemia in COVID-19 Patients.

    Alonso, María Noelia / Mata-Forte, Tatiana / García-León, Natalia / Vullo, Paula Agostina / Ramirez-Olivencia, Germán / Estébanez, Miriam / Álvarez-Marcos, Francisco

    Vascular health and risk management

    2020  Volume 16, Page(s) 467–478

    Abstract: Aim: In addition to its respiratory impact of SARS-CoV2, skin lesions of probable vascular origin have been described. This study intends to quantify the incidence of acro-ischemic lesions in COVID-19 infected adult subjects in our population, ... ...

    Abstract Aim: In addition to its respiratory impact of SARS-CoV2, skin lesions of probable vascular origin have been described. This study intends to quantify the incidence of acro-ischemic lesions in COVID-19 infected adult subjects in our population, describing clinical patterns and associated findings.
    Methods: All adult confirmed cases of COVID-19 infection who presented with acro-ischemic lesions and received care in our institution were prospectively enrolled up to May 15th, 2020. The variables included demographics, comorbidities, analytical parameters, clinical presentations and COVID-19 treatment.
    Results: We enrolled 24 patients. The overall rate of acro-ischemic findings in COVID-19 patients was 1.2% [0.6% for outpatients and 2.9% for hospitalized (ICU and non-ICU patients)], but the observed incidence for acro-ischemia in ICU patients was remarkably higher (23.0%, p<0.001). We have described four different clinical patterns of acroischemia: atypical Raynaud´s phenomenon (ARP), (4); pseudo-pernio (PP), (5); severe microcirculatory ischemia with preserved pulse (SMI), (6); and dry gangrene with arteriosclerosis obliterans (AO), (9). Kendall´s τ correlation with lung disease severity was 0.877 (95% CI, 0.756 to 0.968); p<0.01). ARP individuals were predominantly female, while SMI appeared lately in elderly hospitalized subjects with better prognosis. AO occurred in patients with more comorbidity and younger than those with SMI. We observed other associated lesions of suggestive ischemic nature in other organs in all groups (15 patients of total sample). Plasma procalcitonin was significantly higher in patients who developed SMI (median and interquartile range: 9.99 (4.2, 12.3) mg/mL vs 0.26 (0.11, 0.89) mg/mL; p<0.001), and D-dimer level at hospital admission was significantly higher in AO patients (median and interquartile range: 1166 (1050, 2111) mg/L vs 502 (448, 777) mg/L; p<0.001).
    Conclusion: The observed risk for acroischemia in COVID-19 is high in ICU patients (23%). We have described four different clinical patterns of acroischemia (ARP, PP, SMI and AO) associated with lung disease severity. Authors have communicated various lesions of suggestive ischemic nature in other organs. Raynaud-like pattern is reported as a "novelty".
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/diagnosis ; COVID-19/drug therapy ; COVID-19/epidemiology ; Chilblains/diagnosis ; Chilblains/drug therapy ; Chilblains/epidemiology ; Comorbidity ; Female ; Gangrene ; Humans ; Incidence ; Ischemia/diagnosis ; Ischemia/drug therapy ; Ischemia/epidemiology ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Raynaud Disease/diagnosis ; Raynaud Disease/drug therapy ; Raynaud Disease/epidemiology ; Risk Factors ; Skin/blood supply ; Skin/pathology ; Spain/epidemiology
    Language English
    Publishing date 2020-11-24
    Publishing country New Zealand
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2186568-1
    ISSN 1178-2048 ; 1176-6344
    ISSN (online) 1178-2048
    ISSN 1176-6344
    DOI 10.2147/VHRM.S276530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Use of ribavirin in viruses other than hepatitis C. A review of the evidence.

    Ramírez-Olivencia, German / Estébanez, Miriam / Membrillo, Francisco Javier / Ybarra, Maria Del Carmen

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2018  Volume 37, Issue 9, Page(s) 602–608

    Abstract: Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitisC virus. However, there are other diseases in which it could be of benefit and it ... ...

    Title translation Uso de ribavirina en virus distintos de la hepatitis C. Una revisión de la evidencia.
    Abstract Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitisC virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.
    MeSH term(s) Adenoviridae Infections/drug therapy ; Adenoviruses, Human/drug effects ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Arenaviruses, New World/drug effects ; Clinical Trials as Topic ; Coronavirus Infections/drug therapy ; Orthohantavirus/drug effects ; Hantavirus Infections/drug therapy ; Hemorrhagic Fever Virus, Crimean-Congo/drug effects ; Hemorrhagic Fever, American/drug therapy ; Hemorrhagic Fever, Crimean/drug therapy ; Humans ; Lassa Fever/drug therapy ; Lassa virus/drug effects ; Meta-Analysis as Topic ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Respiratory Syncytial Virus Infections/drug therapy ; Respiratory Syncytial Viruses/drug effects ; Ribavirin/therapeutic use ; Virus Diseases/drug therapy ; Viruses/drug effects
    Chemical Substances Antiviral Agents ; Ribavirin (49717AWG6K)
    Keywords covid19
    Language Spanish
    Publishing date 2018-06-12
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2018.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Blastocystis hominis y diarrea.

    Ramírez Olivencia, Germán

    Medicina clinica

    2007  Volume 129, Issue 15, Page(s) 598; author reply 598

    Title translation Blastocystis hominis and diarrhea.
    MeSH term(s) Animals ; Blastocystis Infections/complications ; Blastocystis hominis ; Diarrhea/parasitology ; Feces/parasitology ; Humans
    Language Spanish
    Publishing date 2007-01-11
    Publishing country Spain
    Document type Comment ; Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1157/13111717
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  7. Article ; Online: Uso de ribavirina en virus distintos de la hepatitis C. Una revisión de la evidencia.

    Ramírez-Olivencia, German / Estébanez, Miriam / Membrillo, Francisco Javier / Ybarra, Maria Del Carmen

    Enfermedades infecciosas y microbiologia clinica

    2018  Volume 37, Issue 9, Page(s) 602–608

    Abstract: Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of benefit and it ...

    Title translation Use of ribavirin in viruses other than hepatitis C. A review of the evidence.
    Abstract Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.
    Language Spanish
    Publishing date 2018-06-12
    Publishing country Spain
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2018.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Use of ribavirin in viruses other than hepatitis C. A review of the evidence

    Ramírez-Olivencia, German / Estébanez, Miriam / Membrillo, Francisco Javier / Ybarra, Maria del Carmen

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    Abstract: Abstract Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of ... ...

    Abstract Abstract Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/j.eimce.2018.05.018
    Database COVID19

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  9. Article ; Online: ¿Yo con sífilis y tú con sida?

    Valencia, Eulalia / Moreno, Victoria / Ramírez-Olivencia, Germán / Gutiérrez, Maite

    Enfermedades infecciosas y microbiologia clinica

    2011  Volume 29, Issue 2, Page(s) 160–161

    Title translation Me with syphilis and you with AIDS?.
    MeSH term(s) Adult ; Aged ; Comorbidity ; Emigrants and Immigrants/statistics & numerical data ; Equatorial Guinea/ethnology ; Female ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/psychology ; Humans ; Latin America/ethnology ; Male ; Middle Aged ; Sexual Partners/psychology ; Spain/epidemiology ; Syphilis/diagnosis ; Syphilis/epidemiology ; Syphilis/psychology ; Truth Disclosure ; Unsafe Sex/prevention & control ; Unsafe Sex/psychology ; Young Adult
    Language Spanish
    Publishing date 2011-02
    Publishing country Spain
    Document type Letter
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2010.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Loiasis in sub-Saharan migrants living in Spain with emphasis of cases from Equatorial Guinea.

    Puente, Sabino / Ramírez-Olivencia, German / Lago, Mar / Subirats, Mercedes / Bru, Francisco / Pérez-Blazquez, Eugenio / Arsuaga, Marta / de Guevara, Concepción Ladron / de la Calle-Prieto, Fernando / Vicente, Belén / Alonso-Sardón, Montserrat / Belhassen-Garcia, Moncef / Muro, Antonio

    Infectious diseases of poverty

    2020  Volume 9, Issue 1, Page(s) 16

    Abstract: Background: Loiasis is an uncommon and poorly understood parasitic disease outside endemic areas of Africa. The aim of this study was to describe the clinical and biological patterns and treatment of imported loiasis by sub-Saharan migrants diagnosed in ...

    Abstract Background: Loiasis is an uncommon and poorly understood parasitic disease outside endemic areas of Africa. The aim of this study was to describe the clinical and biological patterns and treatment of imported loiasis by sub-Saharan migrants diagnosed in Madrid, Spain.
    Methods: A retrospective study was conducted with sub-Saharan immigrants seen at the Tropical Medicine Unit of the Carlos III Hospital in Madrid, Spain, a reference center, over 19 years. Categorical variables were expressed as frequency counts and percentages. Continuous variables were expressed as the mean and standard deviation (SD) or median and interquartile range (IQR: Q3-Q1). Chi-square tests were used to assess the association between categorical variables. The measured outcomes were expressed as the odds ratio (OR) with a 95% confidential interval. Continuous variables were compared by Student's t-tests or Mann-Whitney U tests. Binary logistic regression models were used. P <  0.05 was considered a statistically significant difference.
    Results: One hundred thirty-one migrants from tropical and subtropical areas with loiasis were identified. Forty-nine patients were male (37.4%). The migrants' mean age (±SD) was 42.3 ± 17.3 years, and 124 (94.7%) were from Equatorial Guinea. The median time (IQR) between arrival in Spain and the first consultation was 2 (1-7) months. One hundred fifteen migrants had eosinophilia, and one hundred thirteen had hyper-IgE syndrome. Fifty-seven patients had pruritus (43.5%), and thirty patients had Calabar swelling (22.9%). Seventy-three patients had coinfections with other filarial nematodes (54.2%), and 58 migrants had only Loa loa infections (45.8%). One hundred two patients (77.9%) were treated; 45.1% (46/102) patients were treated with one drug, and 54.9% (56/102) patients were treated with combined therapy. Adverse reactions were described in 14 (10.7%) migrants.
    Conclusions: Our patients presented early clinical manifestations and few atypical features. Thus, physicians should systematically consider loiasis in migrants with a typical presentation. However, considering that 72.5% of the patients had only positive microfilaremia without any symptoms, we suggest searching for microfilaremia in every migrant from endemic countries for loiasis presenting with eosinophilia.
    MeSH term(s) Adult ; Aged ; Anthelmintics/therapeutic use ; Eosinophilia/diagnosis ; Eosinophilia/epidemiology ; Eosinophilia/etiology ; Equatorial Guinea/ethnology ; Female ; Humans ; Loiasis/diagnosis ; Loiasis/drug therapy ; Loiasis/epidemiology ; Male ; Middle Aged ; Retrospective Studies ; Spain/epidemiology ; Transients and Migrants ; Young Adult
    Chemical Substances Anthelmintics
    Language English
    Publishing date 2020-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2689396-4
    ISSN 2049-9957 ; 2049-9957
    ISSN (online) 2049-9957
    ISSN 2049-9957
    DOI 10.1186/s40249-020-0627-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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