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  1. Article ; Online: Le purpura fulminans de l’enfant.

    Rambaud, Jérôme

    La Revue du praticien

    2021  Volume 71, Issue 5, Page(s) 552

    Title translation Purpura fulminans in children.
    MeSH term(s) Child ; Humans ; Meningococcal Infections ; Purpura Fulminans ; Purpura, Schoenlein-Henoch
    Language French
    Publishing date 2021-09-28
    Publishing country France
    Document type Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sepsis et choc septique de l’enfant et de l’adulte and children.

    Rambaud, Jérôme

    La Revue du praticien

    2021  Volume 71, Issue 5, Page(s) 553–556

    Title translation Sepsis and septic shock in adults.
    MeSH term(s) Adult ; Humans ; Sepsis/diagnosis ; Shock, Septic/diagnosis
    Language French
    Publishing date 2021-09-28
    Publishing country France
    Document type Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Predictive value of microcirculation for pediatric extracorporeal membrane oxygenation weaning test: A monocentric prospective observational study.

    Suc, Violette / Starck, Julie / Levy, Yael / Soreze, Yohan / Rambaud, Jerome / Léger, Pierre-Louis

    Artificial organs

    2024  

    Abstract: Background: Extracorporeal membrane oxygenation (ECMO) is widely used for children treated for refractory respiratory failures or refractory cardiogenic shock. Its duration depends on organ functions recovery. Weaning is decided using macro-circulatory ... ...

    Abstract Background: Extracorporeal membrane oxygenation (ECMO) is widely used for children treated for refractory respiratory failures or refractory cardiogenic shock. Its duration depends on organ functions recovery. Weaning is decided using macro-circulatory tools, but microcirculation is not well evaluated. Sidestream dark-field video imaging is used to assess the perfusion of the sublingual microvascular vessels. The aim of this study was to assess the predictive value of microcirculatory indices in ECMO weaning.
    Methods: This prospective monocentric study examined pediatric patients at Trousseau Hospital between March 2017 and December 2020. The study included all patients from 35 weeks of gestational age to 18 years old who were treated with ECMO. Children were divided into two groups: one with stability after weaning and the other with instability after weaning. We collected clinical and biological data, ventilation parameters, extracorporeal membrane oxygenation parameters, and drugs used at admission and after the weaning test. Microcirculations videos were taken after weaning trials with echocardiography and blood gas monitoring.
    Results: The study included 30 patients with a median age of 29 days (range: 1-770 days) at admission, including 18 patients who received venoarterial ECMO (60%). There were 19 children in the stability group and 11 in the instability group. Macrocirculatory and microcirculatory indices showed no differences between groups. The microvascular flow index was subnormal in both groups (2.3 (1.8-2.4) and 2.3 (2.3-2.6), respectively; p = 0.24). The microvascular indices were similar between cases of venovenous and venoarterial ECMO and between age groups.
    Conclusion: Microcirculation monitoring at the weaning phase did not predict the failure of ECMO weaning.
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441812-8
    ISSN 1525-1594 ; 0160-564X
    ISSN (online) 1525-1594
    ISSN 0160-564X
    DOI 10.1111/aor.14754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Extracorporeal Membrane Oxygenation in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.

    Rambaud, Jérome / Barbaro, Ryan P / Macrae, Duncan J / Dalton, Heidi J

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2023  Volume 24, Issue 12 Suppl 2, Page(s) S124–S134

    Abstract: Objectives: To systematically review and assimilate literature on children receiving extracorporeal membrane oxygenation (ECMO) support in pediatric acute respiratory distress syndrome (PARDS) with the goal of developing an update to the Pediatric Acute ...

    Abstract Objectives: To systematically review and assimilate literature on children receiving extracorporeal membrane oxygenation (ECMO) support in pediatric acute respiratory distress syndrome (PARDS) with the goal of developing an update to the Pediatric Acute Lung Injury Consensus Conference recommendations and statements about clinical practice and research.
    Data sources: Electronic searches of MEDLINE (Ovid), Embase (Elsevier), and CINAHL Complete (EBSCOhost).
    Study selection: The search used a medical subject heading terms and text words to capture studies of ECMO in PARDS or acute respiratory failure. Studies using animal models and case reports were excluded from our review.
    Data extraction: Title/abstract review, full-text review, and data extraction using a standardized data collection form.
    Data synthesis: The Grading of Recommendations Assessment, Development, and Evaluation approach was used to identify and summarize evidence and develop recommendations. There were 18 studies identified for full-text extraction. When pediatric data was lacking, adult and neonatal data from randomized clinical trials and observational studies were considered. Six clinical recommendations were generated related to ECMO indications, initiation, and management in PARDS. There were three good practice statements generated related to ECMO indications, initiation, and follow-up in PARDS. Two policy statements were generated involving the impact of ECMO team organization and training in PARDS. Last, there was one research statement.
    Conclusions: Based on a systematic literature review, we propose clinical management, good practice and policy statements within the domains of ECMO indications, initiation, team organization, team training, management, and follow-up as they relate to PARDS.
    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation ; Respiratory Distress Syndrome/therapy ; Acute Lung Injury/therapy
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000003164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Severe bronchiolitis in infants less than 12 months old. Authors' reply.

    Milesi, Christophe / Mortamet, Guillaume / Bordessoule, Alice / Rambaud, Jérôme / Emeriaud, Guillaume

    Intensive care medicine

    2023  Volume 49, Issue 7, Page(s) 888–889

    MeSH term(s) Infant ; Humans ; Bronchiolitis ; Respiratory Therapy ; Acute Disease
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-023-07093-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: French West Indies castaway children as a result of the COVID-19 outbreak.

    Rambaud, Jérôme / Flechelles, Olivier

    Acta paediatrica (Oslo, Norway : 1992)

    2020  Volume 109, Issue 9, Page(s) 1915

    MeSH term(s) Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections ; Disease Outbreaks ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Triage ; West Indies
    Keywords covid19
    Language English
    Publishing date 2020-06-18
    Publishing country Norway
    Document type Letter ; Comment
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.15387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adaptation of Autoencoder for Sparsity Reduction From Clinical Notes Representation Learning.

    Le, Thanh-Dung / Noumeir, Rita / Rambaud, Jerome / Sans, Guillaume / Jouvet, Philippe

    IEEE journal of translational engineering in health and medicine

    2023  Volume 11, Page(s) 469–478

    Abstract: When dealing with clinical text classification on a small dataset, recent studies have confirmed that a well-tuned multilayer perceptron outperforms other generative classifiers, including deep learning ones. To increase the performance of the neural ... ...

    Abstract When dealing with clinical text classification on a small dataset, recent studies have confirmed that a well-tuned multilayer perceptron outperforms other generative classifiers, including deep learning ones. To increase the performance of the neural network classifier, feature selection for the learning representation can effectively be used. However, most feature selection methods only estimate the degree of linear dependency between variables and select the best features based on univariate statistical tests. Furthermore, the sparsity of the feature space involved in the learning representation is ignored.
    Goal: Our aim is, therefore, to access an alternative approach to tackle the sparsity by compressing the clinical representation feature space, where limited French clinical notes can also be dealt with effectively.
    Methods: This study proposed an autoencoder learning algorithm to take advantage of sparsity reduction in clinical note representation. The motivation was to determine how to compress sparse, high-dimensional data by reducing the dimension of the clinical note representation feature space. The classification performance of the classifiers was then evaluated in the trained and compressed feature space.
    Results: The proposed approach provided overall performance gains of up to 3% for each test set evaluation. Finally, the classifier achieved 92% accuracy, 91% recall, 91% precision, and 91% f1-score in detecting the patient's condition. Furthermore, the compression working mechanism and the autoencoder prediction process were demonstrated by applying the theoretic information bottleneck framework. Clinical and Translational Impact Statement- An autoencoder learning algorithm effectively tackles the problem of sparsity in the representation feature space from a small clinical narrative dataset. Significantly, it can learn the best representation of the training data because of its lossless compression capacity compared to other approaches. Consequently, its downstream classification ability can be significantly improved, which cannot be done using deep learning models.
    MeSH term(s) Humans ; Algorithms ; Neural Networks, Computer ; Data Compression ; Correlation of Data
    Language English
    Publishing date 2023-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2696555-0
    ISSN 2168-2372 ; 2168-2372
    ISSN (online) 2168-2372
    ISSN 2168-2372
    DOI 10.1109/JTEHM.2023.3241635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: RE: 'Similar frequency of atrial perforation between atrial and bicaval dual lumen veno-venous ECMO cannulas in a pediatric population'.

    Rambaud, Jerome / Levy, Yael / Leger, Pierre Louis

    Perfusion

    2021  Volume 37, Issue 7, Page(s) 759–760

    MeSH term(s) Cannula ; Child ; Extracorporeal Membrane Oxygenation/adverse effects ; Heart Atria ; Heart Injuries ; Humans ; Respiratory Insufficiency
    Language English
    Publishing date 2021-09-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591211047769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: French West Indies castaway children as a result of the COVID‐19 outbreak

    Rambaud, Jérôme / Flechelles, Olivier

    Acta Paediatrica

    2020  Volume 109, Issue 9, Page(s) 1915–1915

    Keywords Pediatrics, Perinatology, and Child Health ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 0803-5253
    DOI 10.1111/apa.15387
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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