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Article ; Online: A Systematic Review of Studies Comparing Actigraphy Indices in Patients with Depression and Schizophrenia

Ramdas Ransing / Pradeep Patil / Anurag Khapri / Aditya Mahindru

Journal of Clinical and Diagnostic Research, Vol 15, Iss 8, Pp VE01-VE

2021 Volume 04

Abstract: Introduction: Abnormalities in sleep-wake activities are frequently observed among patients with depression and schizophrenia. These abnormalities are variable and may have discriminative, clinical, diagnostic, and therapeutic significance if measured ... ...

Abstract	Introduction: Abnormalities in sleep-wake activities are frequently observed among patients with depression and schizophrenia. These abnormalities are variable and may have discriminative, clinical, diagnostic, and therapeutic significance if measured objectively with actigraphy. Aim: To systematically review the published literature on actigraphy in depression and schizophrenia, particularly to identify areas of research that need to be addressed before their clinical application in practice. Materials and Methods: The electronic databases (PubMed and Google Scholar) were searched for studies using the the key terms ‘actigraphy’ OR ‘actigraphic recording’ OR ‘wrist actigraphy’ OR ‘actometer’ OR ‘actimeter’ OR ‘actical’ OR ‘actiwatch’ OR ‘sleep-watch’ AND ‘schizoaffective’ OR ‘schizophr*’ OR ‘psychosis’ AND ‘depression’ OR ‘depressive’ in title and abstract. The literature search was limited to articles published in English and until 31st December, 2020. Data were abstracted by two reviewers and presented as a narrative summary of the findings. A qualitative synthesis of the study designs, populations, and outcomes was conducted. The quantitative synthesis of the results was not possible to conduct due to the heterogeneity and scarcity of the included studies. Results: Out of 33 searched articles, a total of four studies (three observational and one case report) were included for the review. The included studies were heterogeneous, small in sample size, divergent in methods, inclusive of clinical population, having more than two groups (depression, schizophrenia, mania, or bipolar disorders), and with a low degree of evidence. Overall, the patients with schizophrenia have more structured and less complex activity pattern than those with depression. Furthermore, the patients with schizophrenia showed more irregular patterns in the morning period and increased fluctuations inactivity in the evening period than depression patients. Conclusion: Currently, available information is insufficient to draw firm ...
Keywords	accelerometry ; mental health ; psychosis ; sleep ; Medicine ; R
Subject code	150
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparison of actigraphy indices among patients with depression and schizophrenia

Ramdas Ransing / Pradeep Patil / Swaroopa Patil / Shruti Agrawal

Journal of Family Medicine and Primary Care, Vol 10, Iss 9, Pp 3406-

A preliminary study

2021 Volume 3410

Abstract: Background: Schizophrenia (SCZ) and depression (MDD) are associated with changes in sleep and activity patterns. However, because of a lack of objective evaluation, the diagnostic or clinical value of these sleep-activity patterns is unknown. In this ... ...

Abstract	Background: Schizophrenia (SCZ) and depression (MDD) are associated with changes in sleep and activity patterns. However, because of a lack of objective evaluation, the diagnostic or clinical value of these sleep-activity patterns is unknown. In this study, we attempted to assess and compare the sleep and activity patterns using actigraphy. Materials and Methods: We have recruited 35 patients with SCZ (mean age: 29.29 ± 7.54 years) and 42 patients with MDD (mean age: 27.5 ± 5.59 years) in this cross-sectional study. The actigraphy indices [Time in bed (minutes), Onset latency (minutes), Total sleep time (Minutes), Sleep efficiency (%), WASO (minutes), number of awakening, and activity duration (minutes) were compared among the two groups using unpaired t-test and Fisher exact test. Results: In the MDD group, the time in bed (minutes) was significantly higher than in the SCZ group (402.7 ± 41.97 vs. 379.1 ± 40.45, P = 0.01), while the sleep efficiency was lower in the SCZ group than in the MDD group (60.04 ± 9.25 vs. 65.05 ± 7.16, P = 0.0092). An increase in onset latency (minutes) was observed in the SCZ group compared to the MDD group (49.06 ± 16.09 vs. 43.6 ± 10.14, P = 0.074). The difference in WASO (minutes), the number of awakenings, and activity duration (minutes) among the two groups were insignificant. Conclusion: Actigraphy parameters such as sleep efficiency and time in bed may be a useful sleep process, etiological, and prognostic markers in patients with SCZ and MDD. The longitudinal studies are needed to estimate the predictive role of these parameters for therapeutic outcome in these patients.
Keywords	actigraphy ; actimeter ; depression ; schizophrenia ; Medicine ; R
Subject code	610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: COVID-19 Related Mental Health Issues among Patients with Cancer

Kumari Padma / Deepthi Saka / Sharol Fernandes / Sagar Nanaware / Ishwar Patil / Ramdas Ransing

Journal of Clinical and Diagnostic Research, Vol 16, Iss 7, Pp VC16-VC

A Pilot Study

2022 Volume 20

Abstract: Introduction: Coronavirus Disease-2019 (COVID-19) pandemic is associated with more psychological distress than its rampant spread, mortality, and morbidity. Cancer patients are at increased risk of mortality and morbidity than the general population. Due ...

Abstract	Introduction: Coronavirus Disease-2019 (COVID-19) pandemic is associated with more psychological distress than its rampant spread, mortality, and morbidity. Cancer patients are at increased risk of mortality and morbidity than the general population. Due to this, there is a possibility that cancer patients may be suffering from a higher level of COVID-19 related anxiety, fear, and obsession. Aim: To explore COVID-19 related mental health issues (anxiety, fear, and obsession) and its correlation in patients with cancer. Materials and Methods: The present study was a cross-sectional pilot study which was conducted in a tertiary care teaching hospital located in Ratnagiri, Maharashtra, India. Patients receiving treatment for cancer (n=55) consequently at tertiary care teaching hospital of India were recruited. The Corona Anxiety Scale (CAS), Obsession with COVID-19 Scale (OCS), Fear of COVID-19 Scale (FCV-19S), Patient Health Questionnaire-9 (PHQ-9), and Generalised Anxiety Disorder-7 Scale (GAD-7) were used to assess all eligible patients. Fisher’s-exact test, Spearman’s rank correlation, and logistic regression were used to analyse the data. Results: Among the 55 patients (mean age was 49.64±13.08 years) with cancer, 11 (20%) had Coronavirus related anxiety and 2 (3.6%) had obsession related COVID-19, 22 (40%) had depression and 18 (32.7%) had GAD. CAS score positively correlated with FCV-19S score {ρ=0.50 (p<0.001)}, PHQ-9 score {ρ=0.90 (p<0.001)} and GAD-7 score {ρ=0.74 (p<0.001)}. Conclusion: The COVID-19 related mental health issues (fear, anxiety), depression, and GAD were prevalent among patients with cancer. Further, COVID-19 specific issues may not be addressed in routine screening and evaluation in current practice. Therefore, there is an urgent need to develop systematic strategies to screen and develop specific mental health interventions for patients with cancer.
Keywords	anxiety ; consultation liaison psychiatry depression ; coronavirus disease-19 ; Medicine ; R
Subject code	150
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Second wave of COVID-19 pandemic in India

Sujita Kumar Kar / Ramdas Ransing / S.M.Yasir Arafat / Vikas Menon

EClinicalMedicine, Vol 36, Iss , Pp 100915- (2021)

Barriers to effective governmental response

2021

Keywords	Medicine (General) ; R5-920
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Perinatal mental health in India and Thailand

Chonnakarn Jatchavala, MD, MSc., FRCPsychTH / Sharad Philip, MBBS, MD / Himangshu Malakar, MBBS, MS / Lungan Rongmei, MBBS, MS / Nilesh Devraj, MBBS, MD / Ramdas Ransing, MBBS, MD

Journal of Taibah University Medical Sciences, Vol 18, Iss 6, Pp 1373-

A call for collaboration

2023 Volume 1375

Keywords	Medicine (General) ; R5-920
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Radiation-Induced neuropsychiatric manifestations in a patient with brain metastasis

Kumari Padma / Sagar Nanaware / Nikhil Pande / Ramdas Ransing / Krishnaji Kulkarni

Indian Journal of Palliative Care, Vol 24, Iss 3, Pp 369-

A diagnostic and therapeutic challenges for consultation-liaison psychiatrist

2018 Volume 371

Abstract: The aim of this case report is to highlight diagnostic and therapeutic challenges for consultation-liaison psychiatrist in the case of radiation-induced neuropsychiatric syndrome. We report the case of a 61-year-old man presented with neurological and ... ...

Abstract	The aim of this case report is to highlight diagnostic and therapeutic challenges for consultation-liaison psychiatrist in the case of radiation-induced neuropsychiatric syndrome. We report the case of a 61-year-old man presented with neurological and psychiatric manifestations following the radiation therapy for non-small cell lung carcinoma with brain metastasis. We have briefly reviewed and discussed the risk factors, clinical features, diagnostic, therapeutic, and preventive aspect of radiation-induced neuropsychiatric manifestations.
Keywords	Acute radiation syndrome ; acute stroke ; delirium ; non-small cell lung carcinoma ; Medicine (General) ; R5-920
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A mentored hands-on training model for scaling up implementation and intervention research in India

Ramdas Ransing / Mary Hawk / Margaret McDonald / Jacquelyn Jones / Triptish Bhatia / Vijay Verma / Gyan D. Shah / Jaspreet Brar / James Erin Egan / Prasad Konsale / Jasmine Kaur / Ravinder Singh / Harpreet Singh / R. S. Dhaliwal / Joel Wood / Vishwajit Nimgaonkar / Smita Deshpande / Soumya Swaminathan

Health Research Policy and Systems, Vol 21, Iss 1, Pp 1-

“connecting the dots”

2023 Volume 12

Abstract: Abstract Despite the high burden of mental disorders in low- and middle-income countries (LMICs), less than 25% of those in need have access to appropriate services, in part due to a scarcity of locally relevant, evidence-based interventions and models ... ...

Abstract	Abstract Despite the high burden of mental disorders in low- and middle-income countries (LMICs), less than 25% of those in need have access to appropriate services, in part due to a scarcity of locally relevant, evidence-based interventions and models of care. To address this gap, researchers from India and the United States and the Indian Council of Medical Research (ICMR) collaboratively developed a “Grantathon” model to provide mentored research training to 24 new principal investigators (PIs). This included a week-long didactic training, a customized web-based data entry/analysis system and a National Coordination Unit (NCU) to support PIs and track process objectives. Outcome objectives were assessed via scholarly output including publications, awards received and subsequent grants that were leveraged. Multiple mentorship strategies including collaborative problem-solving approaches were used to foster single-centre and multicentre research. Flexible, approachable and engaged support from mentors helped PIs overcome research barriers, and the NCU addressed local policy and day-to-day challenges through informal monthly review meetings. Bi-annual formal review presentations by all PIs continued through the COVID-19 pandemic, enabling interim results reporting and scientific review, also serving to reinforce accountability. To date, more than 33 publications, 47 scientific presentations, 12 awards, two measurement tools, five intervention manuals and eight research grants have been generated in an open-access environment. The Grantathon is a successful model for building research capacity and improving mental health research in India that could be adopted for use in other LMICs.
Keywords	Grantathon ; Mental health ; Research mentoring ; Capacity-building ; Public aspects of medicine ; RA1-1270
Subject code	306
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Responding to COVID-19

Florian Scheibein / M. J. Stowe / Sidharth Arya / Nirvana Morgan / Tomohiro Shirasaka / Paolo Grandinetti / Noha Ahmed Saad / Abhishek Ghosh / Ramyadarshni Vadivel / Woraphat Ratta-apha / Sagun Ballav Pant / Ramdas Ransing / Rodrigo Ramalho / Angelo Bruschi / Tanay Maiti / Anne Yee HA / Mirjana Delic / Shobhit Jain / Eric Peyron /

Kristiana Siste / Joy Onoria / Saïd Boujraf / Lisa Dannatt / Arnt Schellekens / Tanya Calvey

Frontiers in Psychiatry, Vol

Emerging Practices in Addiction Medicine in 17 Countries

2021 Volume 12

Keywords	COVID-19 ; drug policy ; addiction medicine ; substance use ; behaviourial addictions ; best practice ; Psychiatry ; RC435-571
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Telepsychiatry During the COVID-19 Pandemic

Rodrigo Ramalho / Frances Adiukwu / Drita Gashi Bytyçi / Samer El Hayek / Jairo M. Gonzalez-Diaz / Amine Larnaout / Paolo Grandinetti / Marwa Nofal / Victor Pereira-Sanchez / Mariana Pinto da Costa / Ramdas Ransing / Andre Luiz Schuh Teixeira / Mohammadreza Shalbafan / Joan Soler-Vidal / Zulvia Syarif / Laura Orsolini

Frontiers in Psychiatry, Vol

Development of a Protocol for Telemental Health Care

2020 Volume 11

Abstract: BackgroundThe rapid spread of the Coronavirus disease 2019 (COVID-19) has forced most countries to take drastic public health measures, including the closure of most mental health outpatient services and some inpatient units. This has suddenly created ... ...

Abstract	BackgroundThe rapid spread of the Coronavirus disease 2019 (COVID-19) has forced most countries to take drastic public health measures, including the closure of most mental health outpatient services and some inpatient units. This has suddenly created the need to adapt and expand telepsychiatry care across the world. However, not all health care services might be ready to cope with this public health demand. The present study was set to create a practical and clinically useful protocol for telemental health care to be applied in the context of the current COVID-19 pandemic.MethodsA panel of psychiatrists from 15 different countries [covering all World Health Organization (WHO) regions] was convened. The panel used a combination of reactive Delphi technique and consensus development conference strategies to develop a protocol for the provision of telemental health care during the COVID-19 pandemic.ResultsThe proposed protocol describes a semi-structured initial assessment and a series of potential interventions matching mild, moderate, or high-intensity needs of target populations.ConclusionsTelemedicine has become a pivotal tool in the task of ensuring the continuous provision of mental health care for the population, and the outlined protocol can assist with this task. The strength of this protocol lies in its practicality, clinical usefulness, and wide transferability, resulting from the diversity of the consensus group that developed it. Developed by psychiatrists from around the globe, the proposed protocol may prove helpful for many clinical and cultural contexts, assisting mental health care providers worldwide.
Keywords	COVID-19 ; Coronavirus disease ; mental health ; protocol ; psychiatry ; telemedicine ; RC435-571 ; covid19
Subject code	360
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: COVID-19 mental health care toolkit

Samer El Hayek / Frances Adiukwu / Laura Orsolini / Drita Gashi Bytyçi / Jairo M Gonzalez-Diaz / Amine Larnaout / Paolo Grandinetti / Marwa Nofal / Victor Pereira-Sanchez / Mariana Pinto da Costa / Ramdas Ransing / Andre Luiz Schuh Teixeira / Mohammadreza Shalbafan / Joan Soler-Vidal / Zulvia Syarif / Ganesh Kudva Kundadak / Rodrigo D Ramalho

General Psychiatry, Vol 33, Iss

an international collaborative effort by Early Career Psychiatrists section

2020 Volume 5

Abstract: The collaborative effort of an international research team from the Early Career Psychiatrists section of the World Psychiatry Association has brought about an easy-to-use, quick and stepwise mental health care toolkit for the identification and ... ...

Abstract	The collaborative effort of an international research team from the Early Career Psychiatrists section of the World Psychiatry Association has brought about an easy-to-use, quick and stepwise mental health care toolkit for the identification and appropriate referral of those in need of mental health care during the pandemic. This simple guide can be applied in the general outpatient setting and is catered for all healthcare professionals, regardless of their expertise within the mental health field with minimal training. It is our hope that by incorporating this toolkit into our daily clinical care during the pandemic for high-risk patients and patients with non-specific complaints, we will be able to bridge the mental health gap present in our society.
Keywords	Psychiatry ; RC435-571 ; covid19
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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