Article ; Online: Mechanisms Underlying Vascular Endothelial Growth Factor Receptor Inhibition-Induced Hypertension: The HYPAZ Trial.
Hypertension (Dallas, Tex. : 1979)
2021 Volume 77, Issue 5, Page(s) 1591–1599
Abstract: Figure: see text]. ...
Abstract | [Figure: see text]. |
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MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/administration & dosage ; Angiogenesis Inhibitors/adverse effects ; Angiogenesis Inhibitors/therapeutic use ; Cardiac Output/drug effects ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiopathology ; Female ; Hemodynamics/drug effects ; Humans ; Hypertension/chemically induced ; Hypertension/physiopathology ; Indazoles/administration & dosage ; Indazoles/adverse effects ; Indazoles/therapeutic use ; Male ; Middle Aged ; Neoplasms/drug therapy ; Pyrimidines/administration & dosage ; Pyrimidines/adverse effects ; Pyrimidines/therapeutic use ; Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors ; Sulfonamides/administration & dosage ; Sulfonamides/adverse effects ; Sulfonamides/therapeutic use ; Vascular Resistance/drug effects ; Vascular Stiffness/drug effects |
Chemical Substances | Angiogenesis Inhibitors ; Indazoles ; Pyrimidines ; Sulfonamides ; pazopanib (7RN5DR86CK) ; Receptors, Vascular Endothelial Growth Factor (EC 2.7.10.1) |
Language | English |
Publishing date | 2021-03-29 |
Publishing country | United States |
Document type | Clinical Trial, Phase II ; Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 423736-5 |
ISSN | 1524-4563 ; 0194-911X ; 0362-4323 |
ISSN (online) | 1524-4563 |
ISSN | 0194-911X ; 0362-4323 |
DOI | 10.1161/HYPERTENSIONAHA.120.16454 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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