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  1. Article: Terminalia arjuna

    Ramesh, Purnimajayasree / Palaniappan, Arunkumar

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 1

    Abstract: Herbal medicines were the main source of therapeutic agents in the ancestral era. ...

    Abstract Herbal medicines were the main source of therapeutic agents in the ancestral era.
    Language English
    Publishing date 2023-01-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16010126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Molecularly Imprinted Polymer-Based Biomimetic Systems for Sensing Environmental Contaminants, Biomarkers, and Bioimaging Applications.

    Ramajayam, Kalaipriya / Ganesan, Selvaganapathy / Ramesh, Purnimajayasree / Beena, Maya / Kokulnathan, Thangavelu / Palaniappan, Arunkumar

    Biomimetics (Basel, Switzerland)

    2023  Volume 8, Issue 2

    Abstract: Molecularly imprinted polymers (MIPs), a biomimetic artificial receptor system inspired by the human body's antibody-antigen reactions, have gained significant attraction in the area of sensor development applications, especially in the areas of medical, ...

    Abstract Molecularly imprinted polymers (MIPs), a biomimetic artificial receptor system inspired by the human body's antibody-antigen reactions, have gained significant attraction in the area of sensor development applications, especially in the areas of medical, pharmaceutical, food quality control, and the environment. MIPs are found to enhance the sensitivity and specificity of typical optical and electrochemical sensors severalfold with their precise binding to the analytes of choice. In this review, different polymerization chemistries, strategies used in the synthesis of MIPs, and various factors influencing the imprinting parameters to achieve high-performing MIPs are explained in depth. This review also highlights the recent developments in the field, such as MIP-based nanocomposites through nanoscale imprinting, MIP-based thin layers through surface imprinting, and other latest advancements in the sensor field. Furthermore, the role of MIPs in enhancing the sensitivity and specificity of sensors, especially optical and electrochemical sensors, is elaborated. In the later part of the review, applications of MIP-based optical and electrochemical sensors for the detection of biomarkers, enzymes, bacteria, viruses, and various emerging micropollutants like pharmaceutical drugs, pesticides, and heavy metal ions are discussed in detail. Finally, MIP's role in bioimaging applications is elucidated with a critical assessment of the future research directions for MIP-based biomimetic systems.
    Language English
    Publishing date 2023-06-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics8020245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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