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  1. Article ; Online: Detection of African Swine Fever Virus in

    Craig, Anthony F / Schade-Weskott, Mathilde L / Rametse, Thapelo / Heath, Livio / Kriel, Gideon J P / de Klerk-Lorist, Lin-Mari / van Schalkwyk, Louis / Trujillo, Jessie D / Crafford, Jan E / Richt, Juergen A / Swanepoel, Robert

    Viruses

    2022  Volume 14, Issue 8

    Abstract: We investigated the possibility that sylvatic circulation of African swine fever virus (ASFV) in warthogs ... ...

    Abstract We investigated the possibility that sylvatic circulation of African swine fever virus (ASFV) in warthogs and
    MeSH term(s) African Swine Fever/diagnosis ; African Swine Fever/epidemiology ; African Swine Fever Virus/genetics ; Animals ; Nucleic Acids ; Ornithodoros ; South Africa/epidemiology ; Swine
    Chemical Substances Nucleic Acids
    Language English
    Publishing date 2022-07-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14081617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Investigation of African swine fever outbreaks in pigs outside the controlled areas of South Africa, 2012-2017.

    Janse van Rensburg, Leana / Van Heerden, Juanita / Penrith, Mary-Louise / Heath, Livio E / Rametse, Thapelo / Etter, Eric M C

    Journal of the South African Veterinary Association

    2020  Volume 91, Page(s) e1–e9

    Abstract: South Africa historically experienced sporadic African swine fever (ASF) outbreaks in domestic pigs in the northern parts of the country. This was subsequently indicated to be because of spillover from the sylvatic cycle of ASF between warthog and ... ...

    Abstract South Africa historically experienced sporadic African swine fever (ASF) outbreaks in domestic pigs in the northern parts of the country. This was subsequently indicated to be because of spillover from the sylvatic cycle of ASF between warthog and tampans (soft ticks) in the area. South Africa declared this area an ASF-controlled area in 1935, and the area is still controlled in terms of the Animal Diseases Act, 1984 (Act 35 of 1984). Two main epidemics of ASF in domestic pigs were identified outside of the South African ASF-controlled area. The first occurred in 2012 with outbreaks in Gauteng and Mpumalanga provinces, and the second occurred in 2016-2017 with outbreaks in the North West, Free State and Northern Cape provinces. These were the first ASF epidemics in South Africa associated with transmission of the disease via a domestic cycle. This study found that the spread of ASF in these epidemics was mainly via auctions, swill feeding and scavenging. These three aspects need to be addressed in terms of awareness and education on the disease including implementation of biosecurity measures in order to prevent future ASF outbreaks in South Africa. Specific biosecurity measures should be implemented in the semi-commercial sector to prevent ASF-infected pigs and pig products from being moved to naïve pigs and therefore spreading the disease.
    MeSH term(s) African Swine Fever/epidemiology ; African Swine Fever/prevention & control ; African Swine Fever/psychology ; African Swine Fever/transmission ; Animals ; Disease Outbreaks/veterinary ; South Africa/epidemiology ; Swine
    Language English
    Publishing date 2020-07-16
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 188571-6
    ISSN 2224-9435 ; 1019-9128 ; 0301-0732 ; 0038-2809
    ISSN (online) 2224-9435
    ISSN 1019-9128 ; 0301-0732 ; 0038-2809
    DOI 10.4102/jsava.v91i0.1997
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2384: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Detection of African Swine Fever Virus in Ornithodoros Tick Species Associated with Indigenous and Extralimital Warthog Populations in South Africa

    Craig, Anthony F. / Schade-Weskott, Mathilde L. / Rametse, Thapelo / Heath, Livio / Kriel, Gideon J. P. / de Klerk-Lorist, Lin-Mari / van Schalkwyk, Louis / Trujillo, Jessie D. / Crafford, Jan E. / Richt, Juergen A. / Swanepoel, Robert

    Viruses. 2022 July 26, v. 14, no. 8

    2022  

    Abstract: We investigated the possibility that sylvatic circulation of African swine fever virus (ASFV) in warthogs and Ornithodoros ticks had extended beyond the historically affected northern part of South Africa that was declared a controlled area in 1935 to ... ...

    Abstract We investigated the possibility that sylvatic circulation of African swine fever virus (ASFV) in warthogs and Ornithodoros ticks had extended beyond the historically affected northern part of South Africa that was declared a controlled area in 1935 to prevent the spread of infection to the rest of the country. We recently reported finding antibody to the virus in extralimital warthogs in the south of the country, and now describe the detection of infected ticks outside the controlled area. A total of 5078 ticks was collected at 45 locations in 7/9 provinces during 2019–2021 and assayed as 711 pools for virus content by qPCR, while 221 pools were also analysed for tick phylogenetics. Viral nucleic acid was detected in 50 tick pools representing all four members of the Ornithodoros (Ornithodoros) moubata complex known to occur in South Africa: O. (O.) waterbergensis and O. (O.) phacochoerus species yielded ASFV genotypes XX, XXI, XXII at 4 locations and O. (O.) moubata yielded ASFV genotype I at two locations inside the controlled area. Outside the controlled area, O. (O.) moubata and O. (O.) compactus ticks yielded ASFV genotype I at 7 locations, while genotype III ASFV was identified in O. (O.) compactus ticks at a single location. Two of the three species of the O. (O.) savignyi complex ticks known to be present in the country, O. (O.) kalahariensis and O. (O.) noorsveldensis, were collected at single locations and found negative for virus. The only member of the Pavlovskyella subgenus of Ornithodoros ticks known to occur in South Africa, O. (P.) zumpti, was collected from warthog burrows for the first time, in Addo National Park in the Eastern Cape Province where ASFV had never been recorded, and it tested negative for the viral nucleic acid. While it is confirmed that there is sylvatic circulation of ASFV outside the controlled area in South Africa, there is a need for more extensive surveillance and for vector competence studies with various species of Ornithodoros ticks.
    Keywords African swine fever virus ; Ornithodoros ; Phacochoerus ; antibodies ; genotype ; monitoring ; national parks ; nucleic acids ; phylogeny ; ticks ; vector competence ; viruses ; South Africa
    Language English
    Dates of publication 2022-0726
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14081617
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Clinical presentation of FMD virus SAT1 infections in experimentally challenged indigenous South African goats

    Lazarus, David D / Burroughs, Richard E.J / Fosgate, Geoffrey T / Heath, Livio / Mutowembwa, Paidamoyo B / Opperman, Pamela A / Rametse, Thapelo M / Sirdar, Mohamed M

    Small ruminant research. 2019 Nov., v. 180

    2019  

    Abstract: Foot-and-mouth disease (FMD) is a transboundary animal disease that has a major impact on livestock production and trade. Foot-and-mouth disease virus (FMDV) is a single-stranded RNA virus that infects cloven-hoofed livestock and wildlife. The ... ...

    Abstract Foot-and-mouth disease (FMD) is a transboundary animal disease that has a major impact on livestock production and trade. Foot-and-mouth disease virus (FMDV) is a single-stranded RNA virus that infects cloven-hoofed livestock and wildlife. The susceptibility of South African indigenous goats to FMDV Southern African Territories 1 (SAT1) was investigated after experimental challenge with a mixed SAT1 virus pool. In this study, we present the clinical manifestation of FMDV in five naive goats challenged via the intra-dermolingual route with 104.57 50% tissue culture infective dose (TCID50) FMDV virus pool containing SAT1 SAR/8/10, SAR/10/10 and SAR/21/10. The clinical responses of two vaccinated unchallenged goats maintained as in-contacts are also presented. Clinical scoring of FMDV infection and daily rectal temperatures were recorded and temperatures ≥40 °C were defined as fever. All five challenged goats developed fever within 48 h post challenge with a median fever duration of 5 days. The two unchallenged goats developed fever at 5 and 9 days post-contact with FMD lesions appearing at 4 and 8 days post-contact. Additional clinical signs observed included nasal discharge, ulcerative oral mucosal lesions of the lip and ulcerative interdigital cleft lesions. The pooled FMDV SAT1 infection caused mild clinical signs and natural transmission to reduced-dose vaccinated in-contact indigenous South African goats occurred.
    Keywords fever ; foot-and-mouth disease ; Foot-and-mouth disease virus ; goats ; nose ; signs and symptoms (animals and humans) ; tissue culture ; viruses
    Language English
    Dates of publication 2019-11
    Size p. 15-20.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 286928-7
    ISSN 0921-4488
    ISSN 0921-4488
    DOI 10.1016/j.smallrumres.2019.09.014
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4801: Show issues

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