Result 1 - 10 of total 27
Int J Gynecol Cancer
| Keywords | covid19 |
|---|---|
| Publisher | WHO |
| Document type | Article |
| Note | WHO #Covidence: #839757 |
| Database | COVID19 |
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2023 Volume 173, Page(s) 58–67
Abstract: Background: Despite evidence supporting its use, many Enhanced Recovery After Surgery (ERAS) recommendations remain poorly adhered to and barriers to ERAS implementation persist. In this second updated ERAS® Society guideline, a consensus for optimal ... ...
| Abstract | Background: Despite evidence supporting its use, many Enhanced Recovery After Surgery (ERAS) recommendations remain poorly adhered to and barriers to ERAS implementation persist. In this second updated ERAS® Society guideline, a consensus for optimal perioperative care in gynecologic oncology surgery is presented, with a specific emphasis on implementation challenges. Methods: Based on the gaps identified by clinician stakeholder groups, nine implementation challenge topics were prioritized for review. A database search of publications using Embase and PubMed was performed (2018-2023). Studies on each topic were selected with emphasis on meta-analyses, randomized controlled trials, and large prospective cohort studies. These studies were then reviewed and graded by an international panel according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Results: All recommendations on ERAS implementation challenge topics are based on best available evidence. The level of evidence for each item is presented accordingly. Conclusions: The updated evidence base and recommendations for stakeholder derived ERAS implementation challenges in gynecologic oncology are presented by the ERAS® Society in this consensus review. |
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| MeSH term(s) | Female ; Humans ; Enhanced Recovery After Surgery ; Genital Neoplasms, Female/surgery ; Prospective Studies ; Perioperative Care ; Gynecologic Surgical Procedures |
| Language | English |
| Publishing date | 2023-04-21 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 801461-9 |
| ISSN | 1095-6859 ; 0090-8258 |
| ISSN (online) | 1095-6859 |
| ISSN | 0090-8258 |
| DOI | 10.1016/j.ygyno.2023.04.009 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 885: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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2020 Volume 161, Issue 1, Page(s) 46–55
Abstract: Objective: To assess the benefit of Enhanced Recovery After Surgery (ERAS) on length of stay (LOS), postoperative complications, 30-day readmission, and cost in gynecologic oncology.: Methods: A systematic literature search was performed in MEDLINE, ... ...
| Abstract | Objective: To assess the benefit of Enhanced Recovery After Surgery (ERAS) on length of stay (LOS), postoperative complications, 30-day readmission, and cost in gynecologic oncology. Methods: A systematic literature search was performed in MEDLINE, EMBASE, Cochrane Register of Controlled Trials, and Web of Science for all peer-reviewed cohort studies and controlled trials on ERAS involving gynecologic oncology patients. Abstracts, commentaries, non-controlled studies, and studies without specific data on gynecologic oncology patients were excluded. Meta-analysis was performed on the primary endpoint of LOS. Subgroup analyses were performed based on risk of bias of the studies included, number of ERAS elements, and ERAS compliance. Secondary endpoints were readmission rate, complications, and cost. Results: A total of 31 studies (6703 patients) were included: 5 randomized controlled trials, and 26 cohort studies. Meta-analysis of 27 studies (6345 patients) demonstrated a decrease in LOS of 1.6 days (95% confidence interval, CI 1.2-2.1) with ERAS implementation. Meta-analysis of 21 studies (4974 patients) demonstrated a 32% reduction in complications (OR 0.68, 95% CI 0.55-0.83) and a 20% reduction in readmission (OR 0.80, 95% CI 0.64-0.99) for ERAS patients. There was no difference in 30-day postoperative mortality (OR 0.61, 95% CI 0.23-1.6) for ERAS patients compared to controls. No difference in the odds of complications or reduction in LOS was observed based on number of included ERAS elements or reported compliance with ERAS interventions. The mean cost savings for ERAS patients was $2129 USD (95% CI $712 - $3544). Conclusions: ERAS protocols decrease LOS, complications, and cost without increasing rates of readmission or mortality in gynecologic oncology surgery. This evidence supports implementation of ERAS as standard of care in gynecologic oncology. |
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| Language | English |
| Publishing date | 2020-12-30 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 801461-9 |
| ISSN | 1095-6859 ; 0090-8258 |
| ISSN (online) | 1095-6859 |
| ISSN | 0090-8258 |
| DOI | 10.1016/j.ygyno.2020.12.035 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 885: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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2017 Volume 147, Issue 3, Page(s) 617–620
| MeSH term(s) | Female ; Genital Neoplasms, Female/surgery ; Gynecologic Surgical Procedures/methods ; Gynecology/organization & administration ; Humans ; Perioperative Care/methods ; Perioperative Care/standards ; Practice Guidelines as Topic ; Program Development ; Surgical Oncology/organization & administration |
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| Language | English |
| Publishing date | 2017-09-23 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 801461-9 |
| ISSN | 1095-6859 ; 0090-8258 |
| ISSN (online) | 1095-6859 |
| ISSN | 0090-8258 |
| DOI | 10.1016/j.ygyno.2017.09.023 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 885: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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2009 Volume 61, Issue 4, Page(s) 339–346
Abstract: Advanced laparoscopic procedures are increasingly being used as an alternative to laparotomy in gynecologic surgery. Several reviews have been completed that examine the advantages and drawbacks of this technique. Robotic technology offers the promise of ...
| Abstract | Advanced laparoscopic procedures are increasingly being used as an alternative to laparotomy in gynecologic surgery. Several reviews have been completed that examine the advantages and drawbacks of this technique. Robotic technology offers the promise of overcoming many of the shortcomings of laparoscopy, while preserving classic operative techniques. This review article summarizes some of the most recent literature provided in the arena of robotic assisted radical hysterectomy for the treatment of cervical or endometrial cancer. |
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| MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Case-Control Studies ; Clinical Trials as Topic ; Endometrial Neoplasms/surgery ; Female ; Humans ; Hysterectomy/methods ; Laparoscopy ; Laparotomy ; Length of Stay ; Middle Aged ; Minimally Invasive Surgical Procedures ; Postoperative Complications ; Robotics/utilization ; Treatment Outcome ; Uterine Cervical Neoplasms/surgery ; Video-Assisted Surgery |
| Language | English |
| Publishing date | 2009-08 |
| Publishing country | Italy |
| Document type | Comparative Study ; Evaluation Studies ; Journal Article ; Review |
| ZDB-ID | 80159-8 |
| ISSN | 0026-4784 ; 0325-8793 |
| ISSN | 0026-4784 ; 0325-8793 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Um I Zs.245: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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Annals of oncology : official journal of the European Society for Medical Oncology
2024 Volume 35, Issue 3, Page(s) 248–266
Abstract: The European Society of Gynaecological Oncology, the European Society for Medical Oncology (ESMO) and the European Society of Pathology held a consensus conference (CC) on ovarian cancer on 15-16 June 2022 in Valencia, Spain. The CC panel included 44 ... ...
| Abstract | The European Society of Gynaecological Oncology, the European Society for Medical Oncology (ESMO) and the European Society of Pathology held a consensus conference (CC) on ovarian cancer on 15-16 June 2022 in Valencia, Spain. The CC panel included 44 experts in the management of ovarian cancer and pathology, an ESMO scientific advisor and a methodologist. The aim was to discuss new or contentious topics and develop recommendations to improve and harmonise the management of patients with ovarian cancer. Eighteen questions were identified for discussion under four main topics: (i) pathology and molecular biology, (ii) early-stage disease and pelvic mass in pregnancy, (iii) advanced stage (including older/frail patients) and (iv) recurrent disease. The panel was divided into four working groups (WGs) to each address questions relating to one of the four topics outlined above, based on their expertise. Relevant scientific literature was reviewed in advance. Recommendations were developed by the WGs and then presented to the entire panel for further discussion and amendment before voting. This manuscript focuses on the recommendation statements that reached a consensus, their voting results and a summary of evidence supporting each recommendation. |
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| MeSH term(s) | Humans ; Female ; Medical Oncology ; Societies, Medical ; Spain ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/therapy ; Molecular Biology |
| Language | English |
| Publishing date | 2024-02-01 |
| Publishing country | England |
| Document type | Practice Guideline |
| ZDB-ID | 1025984-3 |
| ISSN | 1569-8041 ; 0923-7534 |
| ISSN (online) | 1569-8041 |
| ISSN | 0923-7534 |
| DOI | 10.1016/j.annonc.2023.11.015 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2862: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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2019 Volume 22, Issue 8, Page(s) 1272–1279
Abstract: Purpose: There is a gap in knowledge regarding the impact of micrometastases (MIC) and isolated tumor cells (ITCs) found in the sentinel lymph nodes of patients with endometrial cancer. Here, we present a meta-analysis of the published literature on the ...
| Abstract | Purpose: There is a gap in knowledge regarding the impact of micrometastases (MIC) and isolated tumor cells (ITCs) found in the sentinel lymph nodes of patients with endometrial cancer. Here, we present a meta-analysis of the published literature on the rate of MIC and ITCs after lymphatic mapping and determine trends in postoperative management. Methods: Literature search of Medline and PubMed was done using the terms: micrometastases, isolated tumor cells, endometrial cancer, and sentinel lymph node. Inclusion criteria were: English-language manuscripts, retrospectives, or prospective studies published between January 1999 and June 2019. We removed manuscripts on sentinel node mapping that did not specify information on micrometastases or isolated tumor cells, non-English-language articles, no data about oncologic outcomes, and articles limited to ten cases or less. Results: A total of 45 manuscripts were reviewed, and 8 studies met inclusion criteria. We found that the total number of patients with MIC/ITCs was 286 (187 and 99, respectively). The 72% of patients detected with MIC/ITCs in sentinel nodes received adjuvant therapies. The MIC/ITCs group has a higher relative risk of recurrence of 1.34 (1.07, 1.67) than the negative group, even if the adjuvant therapy was given. Conclusion: We noted that there is an increased relative risk of recurrence in patients with low-volume metastases, even after receiving adjuvant therapy. Whether adjuvant therapy is indicated remains a topic of debate because there are other uterine factors implicated in the prognosis. Multi-institutional tumor registries may help shed light on this important question. |
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| MeSH term(s) | Endometrial Neoplasms/pathology ; Female ; Humans ; Neoplasm Micrometastasis/pathology ; Neoplasm Recurrence, Local ; Prospective Studies ; Retrospective Studies ; Sentinel Lymph Node/pathology ; Sentinel Lymph Node Biopsy/statistics & numerical data |
| Language | English |
| Publishing date | 2019-12-20 |
| Publishing country | Italy |
| Document type | Journal Article ; Meta-Analysis ; Systematic Review |
| ZDB-ID | 2397359-6 |
| ISSN | 1699-3055 ; 1699-048X |
| ISSN (online) | 1699-3055 |
| ISSN | 1699-048X |
| DOI | 10.1007/s12094-019-02249-x |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 6644: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2016 Volume 71, Issue 6, Page(s) 515–522
Abstract: Aim: To determine the ability of magnetic resonance imaging (MRI) in detecting tumour-free margins from the internal os (IO).: Materials and methods: A database search yielded 79 women with early-stage cervical cancer who underwent radical ... ...
| Abstract | Aim: To determine the ability of magnetic resonance imaging (MRI) in detecting tumour-free margins from the internal os (IO). Materials and methods: A database search yielded 79 women with early-stage cervical cancer who underwent radical hysterectomy and preoperative MRI. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI in assessment of ≤5 and >5 mm IO involvement were calculated with histopathological surgical specimen findings considered to be the reference standard. A main and subset analysis was performed. The subset analysis included only those patients who would have been considered for radical trachelectomy. Results: For predicting a distance between the tumour and the IO of ≤5 mm, MRI had a sensitivity of 73%, a specificity of 98.3%, a PPV of 95%, a NPV of 88.1%, and an accuracy of 89.8% for the main analysis, and sensitivity of 81.8%, a specificity of 93.2% a PPV of 69.2% a NPV of 96.5% and an accuracy of 91.4% for the subset analysis. Conclusion: MRI has high specificity, NPV, and accuracy in detecting tumour from the IO, making MRI suitable for treatment planning in patients desiring trachelectomy to preserve fertility. |
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| MeSH term(s) | Adult ; Cervix Uteri/diagnostic imaging ; Cervix Uteri/pathology ; Cervix Uteri/surgery ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Margins of Excision ; Neoplasm Grading ; Preoperative Care/methods ; Reproducibility of Results ; Sensitivity and Specificity ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/surgery ; Young Adult |
| Language | English |
| Publishing date | 2016-06 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 391227-9 |
| ISSN | 1365-229X ; 0009-9260 |
| ISSN (online) | 1365-229X |
| ISSN | 0009-9260 |
| DOI | 10.1016/j.crad.2016.02.009 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ue I Zs.201: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2016 Volume 143, Issue 3, Page(s) 596–603
Abstract: Objectives: To longitudinally assess quality of life (QOL) in women undergoing radical trachelectomy for early-stage cervical cancer.: Methods: We prospectively enrolled patients with stage IA1-IB1 cervical cancer prior to undergoing radical ... ...
| Abstract | Objectives: To longitudinally assess quality of life (QOL) in women undergoing radical trachelectomy for early-stage cervical cancer. Methods: We prospectively enrolled patients with stage IA1-IB1 cervical cancer prior to undergoing radical trachelectomy to complete validated QOL instruments. These instruments included the General Health-Related QOL (SF-12), Functional Assessment of Cancer Therapy-Cervix (FACT-Cx), MD Anderson Symptom Inventory (MDASI), Female Sexual Functioning Index (FSFI), and Satisfaction with Decision scale (SWD). Instruments were filled out at baseline, postoperatively at 6weeks, 6months, 1year, and annually thereafter for 4years. Results: Thirty-nine patients enrolled in the study, and 32 patients were evaluable. The scores for FSFI-arousal (p=0.0002), lubrication (p<0.0001), orgasm (p=0.006), pain (p=0.01), satisfaction (p=0.03) and total score (p=0.004) showed a significant decline at 6weeks then returned to baseline levels by 6 months. The scores for FACT-Cx functional well-being (p=0.02) and physical well-being (p<0.0001), SF-12 bodily pain (p<0.0001), physical functioning (p<0.0001), role physical (p<0.0001), role emotional (p=0.03), social functioning (p=0.002), and MDASI total (p=0.04) showed significantly worsened symptoms at 6weeks then returned to baseline by 6months. The scores for FACT-Cx emotional well-being showed significant worsening of symptoms that persisted at 6-weeks (p=0.004), 6months (p=0.007), 1year (p=0.001), 2years (p=0.002), and 4 years (p=0.03). There was no difference in SWD. Conclusions: Several quality of life assessments decline immediately postoperatively after radical trachelectomy, however, return to baseline thereafter. The long-term emotional impact of this surgery highlights a need for perioperative counseling in these patients. |
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| MeSH term(s) | Activities of Daily Living ; Adenocarcinoma/pathology ; Adenocarcinoma/psychology ; Adenocarcinoma/surgery ; Adult ; Carcinoma/pathology ; Carcinoma/psychology ; Carcinoma/surgery ; Carcinoma, Adenosquamous/pathology ; Carcinoma, Adenosquamous/psychology ; Carcinoma, Adenosquamous/surgery ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/psychology ; Carcinoma, Squamous Cell/surgery ; Female ; Humans ; Longitudinal Studies ; Neoplasm Staging ; Pain, Postoperative/epidemiology ; Patient Satisfaction ; Postoperative Complications/epidemiology ; Postoperative Complications/psychology ; Prospective Studies ; Quality of Life ; Role ; Sexual Dysfunction, Physiological/epidemiology ; Sexual Dysfunction, Physiological/psychology ; Sexual Dysfunctions, Psychological/epidemiology ; Sexual Dysfunctions, Psychological/psychology ; Social Participation ; Trachelectomy/methods ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/psychology ; Uterine Cervical Neoplasms/surgery ; Young Adult |
| Language | English |
| Publishing date | 2016-12 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 801461-9 |
| ISSN | 1095-6859 ; 0090-8258 |
| ISSN (online) | 1095-6859 |
| ISSN | 0090-8258 |
| DOI | 10.1016/j.ygyno.2016.10.012 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 885: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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2001 Volume 13, Issue 5, Page(s) 403–407
Abstract: The concept of sentinel node identification and lymphatic mapping is already established as part of standard practice in the surgical management of breast cancer and melanoma. To reduce extensive radical procedures and decrease morbidity in gynecologic ... ...
| Abstract | The concept of sentinel node identification and lymphatic mapping is already established as part of standard practice in the surgical management of breast cancer and melanoma. To reduce extensive radical procedures and decrease morbidity in gynecologic malignancies, much effort is being focused on implementing less aggressive interventions. By combining the use of radioactive tracers and blue dyes, investigators are identifying sentinel nodes. In vulvar and cervical carcinomas, sentinel node identification may significantly reduce the number of patients undergoing unnecessary, extensive lymphadenectomy in the absence of disease. The addition of novel techniques, such as histopathologic ultrastaging, immunohistochemistry staining, and reverse transcriptase polymerase chain reaction assays, will help increase the accuracy and rate of detection of disease. |
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| MeSH term(s) | Carcinoma/diagnosis ; Carcinoma/pathology ; Coloring Agents ; Female ; Humans ; Immunohistochemistry ; Lymph Node Excision ; Neoplasm Staging ; Radiopharmaceuticals ; Reverse Transcriptase Polymerase Chain Reaction ; Sensitivity and Specificity ; Sentinel Lymph Node Biopsy ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/pathology ; Vulvar Neoplasms/diagnosis ; Vulvar Neoplasms/pathology |
| Chemical Substances | Coloring Agents ; Radiopharmaceuticals |
| Language | English |
| Publishing date | 2001-09 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 1049384-0 |
| ISSN | 1531-703X ; 1040-8746 |
| ISSN (online) | 1531-703X |
| ISSN | 1040-8746 |
| DOI | 10.1097/00001622-200109000-00016 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 3046: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.